CN103550510A - Lotion for treating various vaginitis - Google Patents

Lotion for treating various vaginitis Download PDF

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Publication number
CN103550510A
CN103550510A CN201310593972.1A CN201310593972A CN103550510A CN 103550510 A CN103550510 A CN 103550510A CN 201310593972 A CN201310593972 A CN 201310593972A CN 103550510 A CN103550510 A CN 103550510A
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China
Prior art keywords
lotion
vaginitis
parts
treatment
colpitic
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CN201310593972.1A
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Inventor
张晓甦
朱英
陈霞
于红娟
谈瑄忠
王莉
张艳
许妍妍
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Nanjing Hospital of TCM
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Nanjing Hospital of TCM
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Abstract

The invention discloses a lotion for treating various vaginitis. The lotion is prepared by soaking and boiling the following raw materials in percentage by weight for 3-10min: 15-20 parts of common cnidium fruit, 15-18 parts of amur cork tree bark, 10-13 parts of radix sophorae flavescentis, 12-15 parts of cortex dictamni, 10-12 parts of rhizoma polygonati and 6-9 parts of pepper. The lotion can effectively improve clinical symptoms and signs of patients of vaginitis, and is good in safety; the lotion provides an effective way for treating vaginitis clinically, and is worthy of promotion.

Description

A kind ofly be used for the treatment of all kinds of colpitic lotions
Technical field
The present invention relates to a kind of lotion for the treatment of gynecological inflammation, specifically treat all kinds of colpitic lotions.
Background technology
Vaginitis is common gynecological disease, in TCM Gynecology, without the name of disease of " vaginitis ", records, and because of its clinical manifestation profuse leukorrhea, color, matter, abnormal smells from the patient is abnormal and pudendum, pruritus of vagina, therefore belong to the category of " leukorrheal diseases ", " pudendal pruritus ".Motherland's medical science thinks that its main pathogenesis is damp invasion of lower energizer, and treatment be take clearing heat, detoxicating, dispelling dampness as main.
CN201110002918.6 relates to a kind of colpitic preparation for the treatment of, and ornidazole 1~20 mass parts and chlorhexidine acetate 1~10 mass parts and pharmaceutic adjuvant, consists of.Be a kind of inhibiting-bacteria preparation of Western medicine compound, unsuitable wide spectrum is used, and also should not be prepared into lotion.
CN201210013747 relates to a kind of colpitic lotion for the treatment of, and it is to be made by the material of following weight proportioning and pharmaceutically acceptable carrier: Herba Lophatheri 3-7 part, Radix Gentianae 5-10 part, Radix Stemonae 1-5 part, Cortex Magnoliae Officinalis 5-15 part, Flos Lonicerae 1-5 part, Rhizoma Polygoni Cuspidati 1-5 part, Fructus Cnidii 5-10 part, Cortex Dictamni 3-8 part, Fructus Forsythiae 5-10 part, Indigo Naturalis 3-8 part.Relate to a kind of colpitic lotion for the treatment of with CN201010146995, it is made by weight by following bulk drugs: 1~10 part of Fructus Cnidii, 1~10 part of Galla Chinensis, 1~10 part of Flos Lonicerae, 1~5 part of Radix Angelicae Sinensis, 1~10 part of Herba Asari, 1~5 part of Folium Isatidis, 1~5 part of Radix Sophorae Flavescentis, 1~10 part of Radix Saposhnikoviae, 1~10 part of Fructus Gardeniae, 1~10 part of the Radix Stemonae.
The effect such as Fructus Cnidii warming the kidney to activate YANG, parasite killing, rheumatism, scabies eczema wherein, utilize Fructus Cnidii to have the effect of anti-trichomonal disease, < < prescriptions worth thousand gold > > records, " Semen Cuscutae, Fructus Cnidii, each decile of Fructus Schisandrae Chinensis.Upper three tastes, end, honeyed pill is as Firmiana simplex seed.Drink-service 30 balls, day three." above prescription also take dispel the wind, pudendal pruritus etc. is as main under parasite killing, treatment belt, without compound compatibility effect, unsuitable wide spectrum is used the lotion of bacterial vaginitis as treatment function.
Summary of the invention
The present invention seeks to, propose a kind of all kinds of colpitic lotions for the treatment of, a kind of Chinese medicine lotion is provided, by vagina lavation and local application's treatment vaginitis; Especially the vaginitis of broad spectrum activity.
Technical scheme of the present invention is: a kind ofly treat all kinds of colpitic lotions, made: Fructus Cnidii 15-20 part, Cortex Phellodendri 15-18 part by the raw material of following weight proportioning and pharmaceutically acceptable carrier, Radix Sophorae Flavescentis 10-13 part, Cortex Dictamni 12-15 part, SHENGHUANG essence 10-12 part, Pericarpium Zanthoxyli 6-9 part; Above-mentioned raw materials generally boils 3-10 minute through soaking.
Further, separately add Radix Gentianae 6-9 part.
Beneficial effect of the present invention, through clinical practice, bacterial vaginosis 68 examples wherein, sick 56 examples of pudendum candidiasis, trichomonal vaginitis 54 examples, senile vaginitis 49 examples.7 was 1 course for the treatment of, observed clinical efficacy after treating for 2 courses for the treatment of.Result: bacterial vaginosis group total cure rate 88.2%, total effective rate 100%, the sick group of pudendum candidiasis total cure rate 85.7%, total effective rate 100%, trichomonal vaginitis group total cure rate 96.3%, total effective rate 100%, senile vaginitis group total cure rate 81.6%, total effective rate 98%.Lotion can effectively improve vaginitis patient clinical sings and symptoms, and safety is good, for the colpitic effective way of clinical treatment, is worthy to be popularized.
Lotion of the present invention is on the basis of differentiation of tcm, in conjunction with Chinese medicine modern pharmacological research, forms, and square medicine forms scientific and reasonable.Cortex Phellodendri heat clearing and damp drying wherein, eliminating fire and detoxication, clear part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels noxious dampness.Radix Sophorae Flavescentis heat clearing and damp drying, wind dispelling insecticide, diuresis, better to damp-heat vaginal discharge, pudendal pruritus effect.< < Compendium of Materia Medica > > says: " bitter cold of Radix Sophorae Flavescentis, Cortex Phellodendri, all can the kidney invigorating.Lid is got its bitter dampness, and tremble with fear and remove thermal balance also, hot air wind producing, humidogene worm, therefore can control wind parasite killing again." making damp and hot sick must removing, modern study shows that Cortex Phellodendri, Radix Sophorae Flavescentis have inhibitory action to multiple pathogenic microorganisms.Cortex Dictamni heat clearing and damp drying, the removing toxic substances of dispeling the wind, studies have shown that it has inhibitory action in various degree to multiple pathomycete.SHENGHUANG essence is the product of reinforcing both QI and YIN, and nature and flavor are sweet flat, and modern study shows that it can improve body's immunity, and multiple pathomycete and staphylococcus aureus are had to inhibitory action, reaches strengthening vital QI to eliminate pathogenic factors object.Fructus Cnidii warming the kidney to invigorate YANG, cold expelling dispels the wind, removing dampness and killing parasites, < < Bencao Congxin > > records Fructus Cnidii, and " removing dampness and killing parasites is controlled impotence capsule wet, woman's pain over the perineum pudendal pruritus." modern pharmacological research confirmation, Fructus Cnidii has directly kills infusorian effect.Pericarpium Zanthoxyli distributes drug effect, warming middle-JIAO, pain relieving, parasite killing.Radix Gentianae is apt to clear damp-heat in lower-JIAO.All medicines share, and play altogether heat-clearing and toxic substances removing, dampness leukorrhagia stopping, sterilizing and itch-relieving effect.The lavation of lotion vagina can make the medicine sick institute that goes directly, determined curative effect, and cure rate is high, without wound, have no side effect, and easy and simple to handle.
The specific embodiment
1) the present invention fills a prescription as follows:
Figure BDA0000418733350000021
Figure BDA0000418733350000031
The unit gram of more than filling a prescription, formula 1-10 adopts and extracts solvent is water, through soaking to boil, within 5 minutes, drains as vagina lavation.During use, dilute again 5-15 water doubly.
2) this lotion effect:
Cortex Phellodendri heat clearing and damp drying, eliminating fire and detoxication, except hectic fever due to YIN-deficiency clearind deficient heat; Cortex Dictamni is most commonly used to treat skin itching sore due to damp and hot stasis, eczema, eczema scrotum, scabies, wind skin ulcer etc., and Pericarpium Zanthoxyli distends the blood vessels, thereby plays the effect reducing blood pressure; Pepper water can be removed parasite; Warming spleen and stomach for dispelling cold, removing damp and stopping pain, parasite killing removing toxic substances, antipruritic.Radix Gentianae nature and flavor are sweet, cold, the special heat clearing and damp drying of merit, and its eliminating pathogen in the liver gallbladder excess-fire effect is very strong, and can the pain relieving of endogenous wind stopping relieving convulsion.Lotion can effectively improve vaginitis patient clinical sings and symptoms, and safety is good, is the colpitic effective way of clinical treatment.
The applicant uses in the 227 routine clinical observations of the yellow lotion vagina of described Serpentis Lavage for Treatment vaginitis, and the equal indistinction of each effect of filling a prescription, observes and inquire into the colpitic clinical efficacy of lotion for treatment of the present invention.Method: with the yellow lotion vagina of Serpentis Lavage for Treatment 227 routine vaginitis patients, bacterial vaginosis 68 examples wherein, sick 56 examples of pudendum candidiasis, trichomonal vaginitis 54 examples, senile vaginitis 49 examples.7 was 1 course for the treatment of, observed clinical efficacy after treating for 2 courses for the treatment of.Result: bacterial vaginosis group total cure rate 88.2%, total effective rate 100%, the sick group of pudendum candidiasis total cure rate 85.7%, total effective rate 100%, trichomonal vaginitis group total cure rate 96.3%, total effective rate 100%, senile vaginitis group total cure rate 81.6%, total effective rate 98%.Conclusion: lotion of the present invention can effectively improve vaginitis patient clinical sings and symptoms, and safety is good, for the colpitic effective way of clinical treatment, is worthy to be popularized.
227 routine patients are the applicant's outpatients of gynecology, patient all has the symptoms such as leucorrhoea grow in quantity, abnormal flavour or pudendum, pruritus of vagina in various degree, bacterial vaginosis 68 examples wherein, sick 56 examples of pudendum candidiasis, trichomonal vaginitis 54 examples, senile vaginitis 49 examples.Patient all belongs to the women who does not wait in age 20-65 year.
Diagnostic criteria, with reference to < < obstetrics and gynecology > > [1]clinical manifestation and the lab testing of the 7th edition textbook.
Fructus Cnidii, Cortex Phellodendri, Radix Sophorae Flavescentis, Cortex Dictamni, SHENGHUANG essence, Pericarpium Zanthoxyli, Radix Gentianae 250ml/ bottle, is diluted to concentration and is 10% irrigating solution, each capable vagina lavation of 150ml, every day 2 times, 7 was 1 course for the treatment of, treated for 2 courses for the treatment of.
Observation of curative effect: criterion of therapeutical effect is drafted with reference to < < new Chinese medicine guideline of clinical investigations > >, recovery from illness: after treatment, clinical symptoms disappears completely, vaginal secretions plate coating checking is negative, the congested petechia for the treatment of provagina or shallow table ulcer transfer to normally, and after continuous 4 menstruations, check is all negative.Effective: treat rear clinical symptom disappearance or be clearly better, accidental infusorian or mycete under vaginal secretions high power lens, check 3 times feminine gender after 4 menstruations.Effective: after treatment, clinical symptoms substantially disappears or takes a turn for the better, accidental under vaginal secretions low power lens, under high power lens, can see infusorian or mycete, checks 2 times feminine gender after 4 menstruations.Invalid: symptom, sign and vaginal secretions inspection are all with before medication.
Efficacy result (in Table 1)
The routine vaginitis treatment result of table 1227 categorised statistical form (example, %)
Safety monitoring, in therapeutic process, does not have patient to tell irritated and special discomfort.
Above-described embodiment is not limitation of the present invention, and lotion itself has certain formula range.Those of ordinary skill in the art, in the situation that not departing from the present invention's spirit and protection domain, can also make various variations and modification, and therefore all technical schemes that are equal to do not exceed protection scope of the present invention yet.

Claims (3)

1. all kinds of colpitic lotions for the treatment of, is characterized in that being boiled and being made for 3-10 minute by the raw material soaking of following weight proportioning: Fructus Cnidii 15-20 part, Cortex Phellodendri 15-18 part, Radix Sophorae Flavescentis 10-13 part, Cortex Dictamni 12-15 part, SHENGHUANG essence 10-12 part, Pericarpium Zanthoxyli 6-9 part.
2. all kinds of colpitic lotions for the treatment of according to claim 1, is characterized in that separately adding Radix Gentianae 6-9 part.
3. all kinds of colpitic lotions for the treatment of according to claim 1, is characterized in that soaking to boil within 5 minutes, draining as vagina lavation lotion.
CN201310593972.1A 2013-11-20 2013-11-20 Lotion for treating various vaginitis Pending CN103550510A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106511568A (en) * 2016-12-21 2017-03-22 南通华津医药保健品有限公司 Antibacterial lotion achieving skin and vagina cleanliness and preparation method and application thereof
CN110974866A (en) * 2019-12-31 2020-04-10 青岛德瑞骏发生物科技股份有限公司 Mare vagina cleaning fluid formula

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
柏敏: "阴痒的治疗和护理", 《医药前沿》 *
黄海梅: "蛇黄洗剂坐浴治疗前庭大腺脓肿初期28例临床观察", 《中医药学报》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106511568A (en) * 2016-12-21 2017-03-22 南通华津医药保健品有限公司 Antibacterial lotion achieving skin and vagina cleanliness and preparation method and application thereof
CN110974866A (en) * 2019-12-31 2020-04-10 青岛德瑞骏发生物科技股份有限公司 Mare vagina cleaning fluid formula

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Application publication date: 20140205