CN103536810B - Medicament for treating breast hyperplasia - Google Patents
Medicament for treating breast hyperplasia Download PDFInfo
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- CN103536810B CN103536810B CN201310559979.1A CN201310559979A CN103536810B CN 103536810 B CN103536810 B CN 103536810B CN 201310559979 A CN201310559979 A CN 201310559979A CN 103536810 B CN103536810 B CN 103536810B
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Abstract
The invention relates to a medicament for treating breast hyperplasia, which is prepared from the following raw medicinal materials in parts by weight: plum blossom, Symplocos leaves, fruit of manglietia fordiana, Cleisostoma williamsonii, green tea, Pteris multifda poir, Cratoxylon ligustrinum tea, mung bean, rhizome of purple bergenia, Herb of Longseed Willowweed, azuki bean, Paphiopedilum parishii, manatee, peanut, stigma of corn, Angelica dahurica, Tinospora sinensis Merr, Agrimonia pilosa Ledeb, Chinese Ladiestresses Root or Herb, Leucosceptrum canum, field bindweed, Nanocnide pilosa Migo and Veronicastrum caulopterum. The medicament for treating breast hyperplasia has the advantages of taking effect quickly, having good curative effect and having no toxic or side effect.
Description
Technical field
The present invention relates to Gynecology, specifically, relate to a kind of medicament for the treatment of cyclomastopathy.
Background technology
Cyclomastopathy refers to the benign proliferative diseases of breast duct epithelium and surrounding connective tissue and lobules of mammary gland, clinical with mastalgia companion lump in breast for principal character, the visible nipple discharge of small number of patients or hemorrhage sexual secretion.Be more common in 25-45 year women, be one of women's commonly encountered diseases, frequently-occurring disease, sickness rate is 30% ~ 40%.The danger that the women's compared with normal crowd suffering from cyclomastopathy suffers from breast cancer obviously increases, and wherein atypical hyperplasia and Breast Cancer closely, are the emphasis of breast carcinoma primary prevention.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of cyclomastopathy.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of cyclomastopathy, it is made up by weight of following bulk drugs: 9 parts, Flos Mume, Folium Symplocoris Caudatae 6 parts, Fructus Manglietiae fordianae 3 parts, Cornu Draconis Fossilia grass 7 parts, green tea 9 parts, Herba Cheilanthes chusane 3 parts, Folium cratoxyli ligustrini 5 parts, 9 parts, Semen phaseoli radiati, 3 parts, Rhizoma Bergeniae scopulosae, Herba Epilobii Pyrricholophi 8 parts, 7 parts, Semen Phaseoli, Philippine Paphiopedilum (Concolor Paphiopedilum) 6 parts, Doris 2 parts, Semen arachidis hypogaeae 3 parts, Stigma Maydis 7 parts, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 3 parts, Herba Lycopodii 2 parts, 5 parts, HUANGLONG tail, Radix seu Herba Spiranthis Lanceae 3 parts, meter Tuan Hua 2 parts, Herba seu Flos Convolvuli arvensis 6 parts, snow medicine 7 parts and Herba Veronicastri caulopteri 6 parts.
Preferably, described medicament is tablet, dispersible tablet, rapidly dissolving tablet, powder or granule.
In the present compositions, Flos Mume, Folium Symplocoris Caudatae, Fructus Manglietiae fordianae, Cornu Draconis Fossilia grass are for being monarch drug; Green tea, Herba Cheilanthes chusane, Folium cratoxyli ligustrini, Semen phaseoli radiati, Rhizoma Bergeniae scopulosae, Herba Epilobii Pyrricholophi are ministerial drug; Semen Phaseoli, Philippine Paphiopedilum (Concolor Paphiopedilum), Doris, Semen arachidis hypogaeae, Stigma Maydis, Radix Angelicae Dahuricae (Radix Heraclei Scabridi), Herba Lycopodii are adjuvant drug; HUANGLONG tail, Radix seu Herba Spiranthis Lanceae, meter Tuan Hua, Herba seu Flos Convolvuli arvensis, snow medicine and Herba Veronicastri caulopteri are for making medicine; Compositions of the present invention plays drug effect best by monarch synergism.
In order to understand the present invention better, with reference to " Chinese medicine voluminous dictionary " second edition, being described as follows of some crude drug used in the present invention:
The medicament for the treatment of cyclomastopathy of the present invention has instant effect, good effect, the advantage that has no side effect.
Detailed description of the invention
Below by way of the description of detailed description of the invention, the invention will be further described, but this is not limitation of the present invention, those skilled in the art are according to basic thought of the present invention, various amendment or improvement can be made, but only otherwise depart from basic thought of the present invention, all within the scope of the present invention.
The preparation of embodiment 1 powder of the present invention
Get 90 grams, Flos Mume, Folium Symplocoris Caudatae 60 grams, Fructus Manglietiae fordianae 30 grams, Cornu Draconis Fossilia grass 70 grams, green tea 90 grams, Herba Cheilanthes chusane 30 grams, Folium cratoxyli ligustrini 50 grams, 90 grams, Semen phaseoli radiati, 30 grams, Rhizoma Bergeniae scopulosae, Herba Epilobii Pyrricholophi 80 grams, 70 grams, Semen Phaseoli, Philippine Paphiopedilum (Concolor Paphiopedilum) 60 grams, Doris 20 grams, Semen arachidis hypogaeae 30 grams, Stigma Maydis 70 grams, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 30 grams, Herba Lycopodii 20 grams, 50 grams, HUANGLONG tail, Radix seu Herba Spiranthis Lanceae 30 grams, meter Tuan Hua 20 grams, Herba seu Flos Convolvuli arvensis 60 grams, snow medicine 70 grams and Herba Veronicastri caulopteri 60 grams, pulverize, cross 100 mesh sieves, then sucrose 250 grams and 150 grams, mannitol is added, mixing, in loading 100 bags and get final product.
Experimental example
Choose patient 60 example, 20 ~ 51 years old age, average 32 years old; The course of disease 2 months ~ 10 years, average 8.5 years; All patients all have breast diffusivity dull pain in various degree or distending pain symptom, have obvious periodicity, how exacerbation of symptoms before menstrual onset, and pain relief or disappearance after menstruation, pain can emit to armpit, the shoulder foot even upper arm of Ipsilateral.Have a medical check-up can touch in Ipsilateral breast and have graininess, lamellar or streak material, most blur margin, have the caking of tenderness.The visible cyclomastopathy in various degree of ultrasound diagnosis, quality is medium, obscure boundary; Noctovisor scan inspection display breast local transparent degree is low, and vascular lake increases, and in netted change, blood vessel is fuzzy.All cases all meet the diagnostic criteria of " new Chinese medicine guideline of clinical investigations " (Ministry of Health of the People's Republic of China, new Chinese medicine guideline of clinical investigations .3 collects [S] .1997:50.).
Use powder obtained in embodiment 1 to treat, wherein one day 1 time, each one bag, treating 10 days is a course for the treatment of.3 courses for the treatment of of continuous treatment.
Criterion of therapeutical effect
The criterion of therapeutical effect of " People's Republic of China's traditional Chinese medicine industry standard " nodules of the breast issued with reference to State Administration of Traditional Chinese Medicine is formulated (ten thousand virtues. hard masses softening and resolving Tonga subtract the routine observation of curative effect for the treatment of cyclomastopathy 600 [[J]. clinical rational drug use, 2011,4 (2A): 62-63.).Effective: in breast, lump disappears, quality deliquescing, pain disappears, and ultrasonic examination prompting shadow disappears, and near infrared ray inspection is normal breast image; Effective: the deliquescing of breast quality, swollen thing reduces 2/3, and premenstrual symptom is obviously alleviated, and ultrasonic examination prompting shadow slightly reduces, and near infrared ray inspection takes a turn for the better than before treatment; Invalid: lump does not reduce, breast pain does not subtract, and near infrared ray inspection is not improved.
Through the treatment of 3 courses for the treatment of, in the breast of discovery all patients, lump disappears, quality deliquescing, and pain disappears, and ultrasonic examination prompting shadow disappears, and near infrared ray inspection is normal breast image, all meets effective criterion of therapeutical effect.
Untoward reaction and toxic and side effects monitoring
By detect patient blood pressure, pulse, whether there is Nausea and vomiting, dizzy clinical symptoms judges untoward reaction.Setting human normal systolic pressure is between 90-140mmHg, diastolic pressure is between 60-90mmHg, human normal pulse is 60-100 beat/min, blood pressure, the pulse of patient is measured at treatments period, find that the blood pressure and pulse recorded is all within normal range, the phenomenon not exceeding normal interval occurs, and does not occur Nausea and vomiting, dizzy clinical symptoms.This illustrates that pharmaceutical composition of the present invention does not have obvious untoward reaction, and then proves that this medicine does not have obvious toxic and side effects for human body.
Claims (1)
1. treat the medicament of cyclomastopathy for one kind, it is characterized in that, it is made up by weight of following bulk drugs: 9 parts, Flos Mume, Folium Symplocoris Caudatae 6 parts, Fructus Manglietiae fordianae 3 parts, Cornu Draconis Fossilia grass 7 parts, green tea 9 parts, Herba Cheilanthes chusane 3 parts, Folium cratoxyli ligustrini 5 parts, 9 parts, Semen phaseoli radiati, 3 parts, Rhizoma Bergeniae scopulosae, Herba Epilobii Pyrricholophi 8 parts, 7 parts, Semen Phaseoli, Philippine Paphiopedilum (Concolor Paphiopedilum) 6 parts, Doris 2 parts, Semen arachidis hypogaeae 3 parts, Stigma Maydis 7 parts, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 3 parts, Herba Lycopodii 2 parts, 5 parts, HUANGLONG tail, Radix seu Herba Spiranthis Lanceae 3 parts, meter Tuan Hua 2 parts, Herba seu Flos Convolvuli arvensis 6 parts, snow medicine 7 parts and Herba Veronicastri caulopteri 6 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310559979.1A CN103536810B (en) | 2013-11-12 | 2013-11-12 | Medicament for treating breast hyperplasia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310559979.1A CN103536810B (en) | 2013-11-12 | 2013-11-12 | Medicament for treating breast hyperplasia |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410614275.4A Division CN104306778A (en) | 2013-11-12 | 2013-11-12 | Agentia for treating hyperplasia of mammary glands |
| CN201410617263.7A Division CN104398876A (en) | 2013-11-12 | 2013-11-12 | Preparation method of medicament for treating mammary gland hyperplasia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103536810A CN103536810A (en) | 2014-01-29 |
| CN103536810B true CN103536810B (en) | 2015-04-01 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310559979.1A Expired - Fee Related CN103536810B (en) | 2013-11-12 | 2013-11-12 | Medicament for treating breast hyperplasia |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579912A (en) * | 2012-04-01 | 2012-07-18 | 李佃场 | Chinese medicinal capsules special for treating acute mastitis and preparation method thereof |
| CN102824458A (en) * | 2012-07-28 | 2012-12-19 | 陈双玲 | Traditional Chinese medicine for qi deficiency and blood stasis type dysmenorrhea |
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2013
- 2013-11-12 CN CN201310559979.1A patent/CN103536810B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579912A (en) * | 2012-04-01 | 2012-07-18 | 李佃场 | Chinese medicinal capsules special for treating acute mastitis and preparation method thereof |
| CN102824458A (en) * | 2012-07-28 | 2012-12-19 | 陈双玲 | Traditional Chinese medicine for qi deficiency and blood stasis type dysmenorrhea |
Non-Patent Citations (1)
| Title |
|---|
| 乳痈的辨证治疗及护理;陈文莉;《河北中医》;20110228;第33卷(第2期);第295-296页 * |
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| CN103536810A (en) | 2014-01-29 |
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