CN103520617B - Chinese medicine enema for treating pediatric mould enteritis - Google Patents

Abstract

The invention discloses a Chinese medicine enema for treating pediatric mould enteritis. The Chinese medicine doctor thinks that the mould enteritis mostly occurs based on the deficiency of qi and yin of the spleen and the stomach; when the vital energy is deficient, the push action is powerless when the yin is deficient, the stomach and intestine is lost of moisturizing and the level declines so as to result in that dampness-heat toxin is happened and stayed for a long time because the operation of intestinal tract qi is unstable and the turbid pathogenic factor is cohered without being dispersed. According to the Chinese medicine enema, the Chinese medicines including fructus alpiniae oxyphyllae, radix cynanchi bungei, light snow ginseng, randia, narrow-leaved oleaster bark, crimson meconopsis, dry beans, chinese toona root-bark, Shen mahonia, ciliatenerve knotweed roots and radices hemerocallis, which have the functions of invigorating spleen and supplementing qi, stopping diarrhoea by activating the energy and clearing away heat and eliminating dampeness, are prepared to be enema. The clinical test shows that the total effective rate is up to 97.5 percent, and the Chinese medicine enema is obviously superior to the contrast group; the Chinese medicine enema has no side effects and the treatment method is simple and convenient.

Description

A kind of Chinese medicinal enema for the treatment of infantile mycotic enteritis

Technical field

The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicinal enema for the treatment of infantile mycotic enteritis.

Background technology

Fungal enteritis is the exedens pseudomembranous enteritis of one caused by fungus attack intestinal mucosa.Mould Pseudomonas fungus scope, the kind of disease cause fungi generally lower more than 20 is not planted, and causing fungal enteritis modal is a kind of fungus being Candida albicans.This Pseudomonas conditioned pathogen, be mainly in the children's of premature infant, malnutrition, weak body that chronic diarrhea is not healed or prolonged application broad ectrum antibiotic, infant times of defecation increases, and every day 3 ~ 5 times, minority can reach 10 times, for yellow loose stool, foam is more, with mucus, and the visible thin block of bean curd slag specimen sometimes, the visible fungus of stool microscopy embraces son and mycelia, and coproculture can have conk.The many delays of the course of disease, treat also cumbersome.Traditional antifungal drug treatment also can bring negative effect to the health of infant.Applicant proves through clinical trial, and utilize herbal drug enema in treatment infantile mycotic enteritis not only to have good curative effect, and method is easy, side effect is little.

Summary of the invention

The object of the invention is to provide a kind of Chinese medicinal enema for the treatment of infantile mycotic enteritis.The traditional Chinese medical science is thought, fungal enteritis is many to be occurred on the basis of taste deficiency of qi and yin, and the deficiency of vital energy then promotes unable, and the cloudy then gastrointestinal that loses loses in the decline that makes moist, and finally cause intestinal mechanism of qi to run not smooth, turbid pathogen is cohesion not to fall apart, and accumulates into Shi Re Bing Pian for a long time, stays for a long time and do not go.Treatment primary disease should with invigorating the spleen and benefiting QI, help fortune antidiarrheal, clearing away heat and eliminating dampness is main principle.

The object of the invention is to be achieved through the following technical solutions, the Chinese medicinal enema of this infantile mycotic enteritis is made up of the Chinese medicine of following weight portion: Fructus Alpiniae Oxyphyllae 10-20 part, Radix Cynanchi Auriculati 10-15 part, Radix Lespedezae Tomentosae 15-25 part, Radix Randiae Sinensis 15-25 part, Cortex Elaeagni Angustifoliae 15-25 part, Scapus et Fructus Meconopsis Puniceae 3-5 part, mountain Shen 15-20 part, Cortex toonae sinensis radicis 10-20 part, Mahonia shenii Chun 15-18 part, Radix Aristolochiae Kaempferi 3-5 part, Radix Hemerocallis 5-15 part.

Preferably, Fructus Alpiniae Oxyphyllae 15 parts, Radix Cynanchi Auriculati 12 parts, Radix Lespedezae Tomentosae 20 parts, Radix Randiae Sinensis 20 parts, Cortex Elaeagni Angustifoliae 20 parts, Scapus et Fructus Meconopsis Puniceae 4 parts, mountain spill 18 parts, Cortex toonae sinensis radicis 15 parts, Mahonia shenii Chun 17 parts, Radix Aristolochiae Kaempferi 4 parts, Radix Hemerocallis 10 parts.

Preparation method by medicinal decocting in above-mentioned, then by the retention enema of decocting liquid filtering residue.

Fang Zhong: Fructus Alpiniae Oxyphyllae strengthening the spleen stomach, reason vigour; Radix Cynanchi Auriculati, Radix Lespedezae Tomentosae yin nourishing tonify deficiency, spleen invigorating is pleasant; Radix Randiae Sinensis eliminating blood stasis to promote regeneration of blood, convergence; Cortex Elaeagni Angustifoliae convergence pain relieving, clearing away heat and cooling blood; Scapus et Fructus Meconopsis Puniceae is astringent or styptic treatment for spontaneous sweating, antibacterial; Mountain Shen enriches blood convergence; Cortex toonae sinensis radicis heat extraction dampness, astringing intestine to stop diarrhea stops blooding; Mahonia shenii Chun clears away heart-fire stomach-fire, removing toxic substances; Radix Aristolochiae Kaempferi relieves inflammation or internal heat detumescence, loose blood and relieving pain; Radix Hemerocallis diuretic removing heat from blood.

Clinical data

1. physical data select year January in January, 2009 to 2012 my Out-patient Department clarify a diagnosis into fungal enteritis infant totally 80 example, be divided into treatment group and matched group at random.Treatment group 40 example, wherein man 25 example, female 15 example; At 2 months-3 years old age, be less than 2 years old person and account for 80%; Acute infant 30 example, unresolved infant 5 example, chronic infant 5 example; Companion dietetic patient 5 example, occur together hot person 20 example, companion's dehydration, acidosis, electrolyte disturbance person 9 example, companion thrush person 31 example, companion's crissum mycotic dermatitis 4 example.Matched group 40 example, wherein man 24 example, female 16 example; At 3 months-3 years old age, be less than 2 years old person and account for 82%; Acute infant 29 example, unresolved infant 6 example, chronic infant 5 example; Companion dietetic patient 4 example, occur together hot person 18 example, companion's dehydration, acidosis, electrolyte disturbance 7 example, companion thrush person 30 example, companion's crissum mycotic dermatitis 4 example.Two groups of infants compare in sex, age, the state of an illness, the course of disease, and no significant difference (P > 0.05), has comparability.

2. diagnostic criteria is with reference to " Chinese diarrhoeal diseases diagnoses and treatment scheme " and subproposal, and drafts in conjunction with clinical: (1) defecates rare Huang, and foam is more, or in bean curd slag specimen, or band mucus.The course of disease was acute within 1 week, and 2 thoughtful February were unresolved, more than February was chronic.(2) accompany low grade fever, yellowish complexion, dehydration and other position fungal infections of whole body, or concurrent malnutrition, digestive tract infect outward.(3) useful hormone, antibiotic history, this uses hormone, antibiotic therapy invalid, and gets rid of bacterial enteritis.(4) microscopy of defecating is shown in fungal spore and false silk, and stool cultivation has fungus growth.

3. Therapeutic Method treatment group adopts herbal drug enema in treatment.Take Fructus Alpiniae Oxyphyllae 15g, Radix Cynanchi Auriculati 12g, Radix Lespedezae Tomentosae 20g, Radix Randiae Sinensis 20g, Cortex Elaeagni Angustifoliae 20g, Scapus et Fructus Meconopsis Puniceae 4g, mountain Shen 18g, Cortex toonae sinensis radicis 15g, Mahonia shenii Chun 17g, Radix Aristolochiae Kaempferi 4g, Radix Hemerocallis 10g, the 500ml that added water top decocts to 100ml, and filtering residue is for subsequent use.After disposable silicone catheter is coated with a small amount of liquid paraffin outward, connects the syringe sucking Chinese herbs decoction, slowly insert 10-15cm from anus, inject medicinal liquid, raise slightly infant buttocks after tube drawing, retain medicinal liquid as far as possible for a long time.Every day 1 time, every 7d is 1 course for the treatment of.Person below June, each 10ml; June above person, each 20ml.Matched group takes antifungal medicine, nystatin 5 ~ 100,000/kg body weight every day, point 3 clothes; Clotrimazole mg/kg body weight every day 20 ~ 60, point 3 clothes, 7d is 1 course for the treatment of.Treat 2 courses for the treatment of all continuously for two groups.

4. criterion of therapeutical effect is drafted with reference to " Chinese diarrhoeal diseases diagnoses and treatment scheme ".Cure: times of defecation, character recover normal, and General Symptoms obviously improves.Effective: times of defecation obviously reduces, stool and General Symptoms make moderate progress.Invalid: times of defecation, character and General Symptoms even worsen without improvement.

5. after therapeutic outcome two groups treats 2 courses for the treatment of, treatment group 40 example, cure 32 examples (80%), effective 7 examples (17.5%), invalid 1 example (2.5%), total effective rate is 97.5%; Matched group 40 example, cure 23 examples (57.5%), effective 10 examples (25%), invalid 7 examples (17.5%), total effective rate is 82.5%; Two groups of cure rates, through statistical procedures, have significant differences (P < 0.01).Treatment group does not have obvious adverse reaction after treatment; Matched group has gastrointestinal upset to react through treatment 70% infant, as diarrhoea, Nausea and vomiting and Upper abdominal pain etc.; 20% infant has the untoward reaction such as numb hand and foot, leukopenia;

6. Typical Case Wang, man, 11 months.More than recurrent diarrhea March.Infant generates heat in 2 wheat harvesting period causes, suffer from diarrhoea, vomit to move back in local hospital treatment after heat and tell only, but diarrhoea does not heal.After this defecating every day 3 ~ 4 times, in scattered paste shape, be water sample sometimes, and amount is lacked, with a small amount of mucus.Once Multiple Classes of Antibiotics treatment was taken, heavy time light during the state of an illness.Then to our hospital, stool microscopy finds mycete (++), is diagnosed as fungal enteritis.Take traditional Chinese medical science enema treatment, take Fructus Alpiniae Oxyphyllae 15g, Radix Cynanchi Auriculati 12g, Radix Lespedezae Tomentosae 20g, Radix Randiae Sinensis 20g, Cortex Elaeagni Angustifoliae 20g, Scapus et Fructus Meconopsis Puniceae 4g, mountain Shen 18g, Cortex toonae sinensis radicis 15g, Mahonia shenii Chun 17g, Radix Aristolochiae Kaempferi 4g, Radix Hemerocallis 10g, the 500ml that added water top decocts to 100ml, and filtering residue is for subsequent use.After disposable silicone catheter is coated with a small amount of liquid paraffin outward, connects the syringe sucking Chinese herbs decoction, slowly insert 10-15cm from anus, inject medicinal liquid, raise slightly infant buttocks after tube drawing, retain medicinal liquid as far as possible for a long time.Every day 1 time, each 20ml.After 5 days, stool examination does not find mycete, treats 3 days above following the service, and stool is shaped, and check stool routine examination is normal.After follow up a case by regular visits to and do not recur half a year.

Detailed description of the invention

Embodiment one: take Fructus Alpiniae Oxyphyllae 15g, Radix Cynanchi Auriculati 12g, Radix Lespedezae Tomentosae 20g, Radix Randiae Sinensis 20g, Cortex Elaeagni Angustifoliae 20g, Scapus et Fructus Meconopsis Puniceae 4g, mountain Shen 18g, Cortex toonae sinensis radicis 15g, Mahonia shenii Chun 17g, Radix Aristolochiae Kaempferi 4g, Radix Hemerocallis 10g, the 500ml that added water top decocts to 100ml, and filtering residue is for subsequent use.

Embodiment two: take Fructus Alpiniae Oxyphyllae 10g, Radix Cynanchi Auriculati 15g, Radix Lespedezae Tomentosae 15g, Radix Randiae Sinensis 25g, Cortex Elaeagni Angustifoliae 15g, Scapus et Fructus Meconopsis Puniceae 5g, mountain Shen 20g, Cortex toonae sinensis radicis 20g, Mahonia shenii Chun 18g, Radix Aristolochiae Kaempferi 5g, Radix Hemerocallis 5g, the 500ml that added water top decocts to 100ml, and filtering residue is for subsequent use.

Embodiment three: take Fructus Alpiniae Oxyphyllae 20g, Radix Cynanchi Auriculati 10g, Radix Lespedezae Tomentosae 25g, Radix Randiae Sinensis 15g, Cortex Elaeagni Angustifoliae 25g, Scapus et Fructus Meconopsis Puniceae 3g, mountain spill 15g, Cortex toonae sinensis radicis 10g, Mahonia shenii Chun 15g, Radix Aristolochiae Kaempferi 3g, Radix Hemerocallis 15g, the 500ml that added water top decocts to 100ml, and filtering residue is for subsequent use.

Claims (2)

1. treat a Chinese medicinal enema for infantile mycotic enteritis, it is characterized in that this Chinese medicinal enema is made up of the Chinese medicine of following weight portion: Fructus Alpiniae Oxyphyllae 10-20 part, Radix Cynanchi Auriculati 10-15 part, Radix Lespedezae Tomentosae 15-25 part, Radix Randiae Sinensis 15-25 part, Cortex Elaeagni Angustifoliae 15-25 part, Scapus et Fructus Meconopsis Puniceae 3-5 part, mountain Shen 15-20 part, Cortex toonae sinensis radicis 10-20 part, Mahonia shenii Chun 15-18 part, Radix Aristolochiae Kaempferi 3-5 part, Radix Hemerocallis 5-15 part.

2. a kind of Chinese medicinal enema for the treatment of infantile mycotic enteritis according to claim 1, is characterized in that this Chinese medicinal enema is made up of the Chinese medicine of following weight portion: Fructus Alpiniae Oxyphyllae 15 parts, Radix Cynanchi Auriculati 12 parts, Radix Lespedezae Tomentosae 20 parts, Radix Randiae Sinensis 20 parts, Cortex Elaeagni Angustifoliae 20 parts, Scapus et Fructus Meconopsis Puniceae 4 parts, mountain Shen 18 parts, Cortex toonae sinensis radicis 15 parts, Mahonia shenii Chun 17 parts, Radix Aristolochiae Kaempferi 4 parts, Radix Hemerocallis 10 parts.