CN103520531A - Traditional Chinese medicinal composition for treating liver depression and qi stagnation type cholecystitis - Google Patents
Traditional Chinese medicinal composition for treating liver depression and qi stagnation type cholecystitis Download PDFInfo
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- CN103520531A CN103520531A CN201310464907.9A CN201310464907A CN103520531A CN 103520531 A CN103520531 A CN 103520531A CN 201310464907 A CN201310464907 A CN 201310464907A CN 103520531 A CN103520531 A CN 103520531A
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Abstract
A traditional Chinese medicinal composition for treating liver depression and qi stagnation type cholecystitis is prepared by using Celastrus aculeatus, Nauclea officinalis, Jasminum grandiflorum, all-grass of Chinese Aeluropus, orange peel, Ligusticum wallichii, mint, Oroxylum indicum, Rhizoma Cyperi and Holboellia latifolia, and can be used for treating the liver depression and qi stagnation type cholecystitis clinically.
Description
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of caused by hepatic stagnation qi stagnation cholecystitis.
Background technology
Chronic cholecystitis is common clinical, frequently-occurring disease, refers to the chronic inflammation pathological changes of gallbladder, how by chronic infection, calculus, chemical stimulation and acute cholecystitis, is repeatedly delayed due to outbreak, has that patient's condition is touching, easy feature repeatedly.In recent years, because work rhythm is accelerated, living standard improves constantly, and the picked-up of fats, high protein diet increases, and primary disease sickness rate is in rising trend.Through inventor's long-term practice, draw, the strongly fragrant qi stagnation cholecystitis of Chinese medicine treating the liver has better effect, obtains good effect.
Summary of the invention
The object of the present invention is to provide the Chinese medicine composition of the treatment caused by hepatic stagnation qi stagnation cholecystitis that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Celastrus aceleatus Merr, Lignum et Radix Naucleae, Flos jasmini, Herba Aeluropi sinensis, Pericarpium Citri junoris, Rhizoma Chuanxiong, Herba Menthae, Semen Oroxyli, Rhizoma Cyperi, Fructus Akebiae according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine composition of the present invention and make 40-60 parts of Celastrus aceleatus Merr, 20-40 parts of Lignum et Radix Naucleae, 20-40 parts of Flos jasmini, 20-40 parts of Herba Aeluropi sinensis, 10-30 parts of Pericarpium Citri junoriss, 10-30 parts of Rhizoma Chuanxiongs, Herba Menthae 10-30 part, 10-30 parts of Semen Oroxylis, 10-30 parts of Rhizoma Cyperis, 8-12 parts of Fructus Akebiaes by following raw material medicaments.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 50 parts of Celastrus aceleatus Merr, 30 parts of Lignum et Radix Naucleae, 30 parts of Flos jasmini, 30 parts of Herba Aeluropi sinensis, 20 parts of Pericarpium Citri junoriss, 20 parts of Rhizoma Chuanxiongs, 20 parts of Herba Menthaes, 20 parts of Semen Oroxylis, 20 parts of Rhizoma Cyperis, 10 parts of Fructus Akebiaes.The pharmacological action of Chinese medicine of the present invention is as follows:
Celastrus aceleatus Merr: bitter, pungent, cool.Return liver, gallbladder, kidney channel.Heat-clearing and toxic substances removing, expelling wind and removing dampness.Clinical in rheumatic arthralgia, gout, nephritis, cholecystitis, the diseases such as leukemia.
Lignum et Radix Naucleae: bitter, cold.Return lung, large intestine, gallbladder, urinary bladder channel.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.Clinical in cold, fever, bronchitis, pneumonia, acute tonsillitis, pharyngolaryngitis, mastitis, enteritis, urinary tract infection, cholecystitis, ulcer of the lower limb, the diseases such as dermatitis and eczema.
Flos jasmini: bitter, flat.Dispersing the stagnated live-QI to relieve the stagnation of QI, promoting the circulation of QI to relieve pain.For the side of body rib gastral cavity abdomen due to stagnation of QI due to depression of the liver, have a pain, the diseases such as dysentery stomachache.Herba Aeluropi sinensis: sweet, light, cool.Clearing away heat and promoting diuresis, jaundice eliminating.Clinical in icterohepatitis, liver cirrhosis, ascites, the diseases such as cholecystitis.Pericarpium Citri junoris: acrid, bitter, warm.Return spleen, lung meridian.Circulation of qi promoting spleen invigorating, lowering the adverse-rising QI and eliminating phlegm.The clinical distension and fullness in the abdomen for stagnation of QI in spleen and stomach, nausea and vomiting, inappetence, expectorant is stopped up the cough with copious phlegm of QI rising in reverse order, and septum pectorale is full vexed, the diseases such as globus hystericus.
Rhizoma Chuanxiong: pungent, warm, return liver, gallbladder, heart channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.For stagnation of QI and blood, rheumatic arthralgia.
Herba Menthae: pungent, cool, GUIXIN, lung, Liver Channel.Dispelling wind and heat pathogens, the clear sharp head, sore-throat relieving, rash, dispersing the stagnated live-QI to relieve the stagnation of QI.For anemopyretic cold, epidemic febrile disease from the beginning of, measles without adequate eruption, rubella pruritus, stagnation of QI due to depression of the liver, hypochondriac pain uncomfortable in chest etc.
Semen Oroxyli: micro-hardship, sweet, be slightly cold.Return lung, liver, stomach warp.Sore-throat relieving lung moistening, dispersing the stagnated liver-QI for regulating the stomach, expelling pus and promoting granulation.For pharyngalgia sore throat, hoarseness, cough, stomachache due to hyperactive liver-QI attacking the stomach, skin infection is burst for a long time and is not more waited disease.
Rhizoma Cyperi: pungent, sweet, micro-hardship, flat.Return liver, tri-jiao channel.Regulate the flow of vital energy resolving depression, regulating menstruation, antiabortive.For distending pain over the hypochondrium, gastral cavity abdomen feeling of fullness pain, abdominal pain during menstruation etc.
Fructus Akebiae: hardship, cool.Return bladder, the heart, Liver Channel.Clearing away heat-damp and promoting diuresis, blood circulation and channel invigorating, promoting the circulation of QI to relieve pain.For oliguria with reddish urine, stranguria with turbid discharge, edema, rheumatic arthralgia, traumatic injury, galactostasis, colicky, uterine prolapse, the diseases such as orchitis.
Caused by hepatic stagnation qi stagnation cholecystitis belongs to the categories such as the traditional Chinese medical science " hypochondriac pain ", " feeling of fullness ".Its cause of disease is many is become estranged by eating and drinking without temperance, the unsuccessful liver network that causes of feelings will.Its sick position is at gallbladder, but relevant with liver and taste.In the present invention, Celastrus aceleatus Merr has the effect of heat-clearing and toxic substances removing, expelling wind and removing dampness, is monarch drug, Lignum et Radix Naucleae heat-clearing and toxic substances removing, Flos jasmini dispersing the stagnated live-QI to relieve the stagnation of QI, promoting the circulation of QI to relieve pain, are ministerial drug, Herba Aeluropi sinensis clearing away heat and promoting diuresis, jaundice eliminating, Pericarpium Citri junoris circulation of qi promoting spleen invigorating, Rhizoma Chuanxiong blood-activating and qi-promoting, pain relieving, Herba Menthae dispersing the stagnated live-QI to relieve the stagnation of QI, Semen Oroxyli dispersing the stagnated liver-QI for regulating the stomach, the Rhizoma Cyperi resolving depression of regulating the flow of vital energy, Fructus Akebiae clearing away heat-damp and promoting diuresis, promoting the circulation of QI to relieve pain.Through clinical practice, find, caused by hepatic stagnation qi stagnation cholecystitis is had to unique curative effect, and all medicines are played the effect of heat-clearing and toxic substances removing, promoting the circulation of QI to relieve pain, soothing liver and strengthening spleen altogether, reach the object for the treatment of caused by hepatic stagnation qi stagnation cholecystitis.
Chinese medicine composition of the present invention was in 2008 to 2011 clinical observation caused by hepatic stagnation qi stagnation cholecystitis 42 routine patients, and clinical report is as follows:
1, physical data
In 42 routine patients, at 18-65 years old ages, the course of disease is many at 3 months to 8 years, 45 years old mean age.
2, diagnostic criteria
" traditional Chinese medical science disease Standardization of diagnosis and curative effect " that 2.1 diagnosis basis State Administration of Traditional Chinese Medicines issue:
1. persistence upper right abdomen dull pain or sense of discomfort ，Huo Banyou omoplate district pain; 2. there are the indigestion symptoms such as nauseating, belch, acid regurgitation, abdominal distention and scorching hot, the postemphasis of feed greasy food; 3. the course of disease is long, and the state of an illness has acute attack and alleviates feature alternately; 4. gallbladder area is carved with mild tenderness and is kowtowed pain; 5. in bile, mucus increases, and leukocyte is in heaps, positive bacterial culture; 6. the visible cholelithiasis of ultrasound diagnosis, thickening of capsule wall of gallbladder, gallbladder dwindles or is out of shape; 7. the visible cholelithiasis of cholecystography, gallbladder dwindles or is out of shape, and gallbladder contraction function is bad, or gallbladder develops thin.
Clinical symptoms: depressed emotion or susceptible to lose temper due to restlessness, side of body rib is altered pain, draws and upper abdomen or shoulder back, oppression sensation over the epigastrium, sighing frequently, belch is frequent, pale tongue with white fur or greasy in vain, stringy and tense pulse.
2.2 exclusion standards:
1. the age is under-18s or over-65s person; 2. acute gangrenous cholecystitis, the suppurative cholecystitis of acute obstruction, perforation of gallbladder peritonitis person; 3. gestation or women breast-feeding their children, be associated with the serious primary disease such as cardiovascular, liver, kidney and hemopoietic system, psychotic.
3, Therapeutic Method
3.1 prescriptions: Celastrus aceleatus Merr 50g, Lignum et Radix Naucleae 30g, Flos jasmini 30g, Herba Aeluropi sinensis 30g, Pericarpium Citri junoris 20g, Rhizoma Chuanxiong 20g, Herba Menthae 20g, Semen Oroxyli 20g, Rhizoma Cyperi 20g, Fructus Akebiae 10g.
3.2 methods of preparation and use: said medicine routinely technique is made decoction, every day 2 times, 15 days were 1 course for the treatment of at 1 dose of every day.
4, therapeutic outcome:
4.1 formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":
Recovery from illness: the primary and secondary syndrome of this syndrome disappears, ultrasound diagnosis gallbladder wall and contractile function recover normal ，Dan district pain and disappear, and diet, digestion recover normal.Drug withdrawal 3 months is unchanged, follows up a case by regular visits to half a year above without recurrence;
Take a turn for the better: this syndrome primary and secondary syndrome is improved and accounted for more than halfly, and ultrasound diagnosis gallbladder wall and the contractile function ，Dan district tenderness that has clear improvement is clearly better, and diet, digestion are clearly better;
Invalid: through treatment symptom, without alleviation, ultrasound diagnosis gallbladder wall and contractile function are without significant change, and every symptom is not improved.
4.2 results: in 42 routine patients, 20 examples of fully recovering (47.6%), 18 examples that take a turn for the better (42.8%), invalid 4 examples (9.6%), total effective rate is 90.4%.
Model case
1, Wang, man, 45 years old.Suffer from cholecystitis 5 years.When medical, hypochondriac pain is indistinctly walked to alter indefinite, connects and also pain of shoulder back, and hypochondriac pain is fixing at nightfall does not move, and xerostomia is bitter, purplish tongue gas, stringy and thready pulse.Ultrasound diagnosis, cyst wall thickens, and volume increases, and gallbladder wall is rough and coarse.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, through B ultrasonic check, and gallbladder clear-cut, smooth, size and form normal, continues to take 2 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after half a year without recurrence.
2, Zhang, female, 36 years old, suffer from cholecystitis 4 years, immediate cause house hold affairs, mind is irritated, side of body rib walks to alter pain, bitterly, and fixing pain at nightfall, during pain, to shoulder back, radiate delayed menstrual cycle, inappetence, appetite reduces, and body of the tongue has purple gas, and thin lingual fur is slightly yellow greasy, stringy and thready pulse, above symptom increases and decreases with feelings will quality.Take medicine of the present invention, 1 dose of every day, after 2 courses for the treatment of, symptom is clearly better, and continues to take 3 courses for the treatment of, through B ultrasonic check, and gallbladder clear-cut, smooth, size and form is normal, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.
3, Liu, man, 51 years old.Because upper right abdominal distention and pain once arrived certain hospital therapy, be diagnosed as acute cholecystitis, give intravenous drip levofloxacin, remission.After this often occur right Upper abdominal pain while not relaxing because of the greasy or feelings will of taking food, and to lower back radiation, companion feels sick, vomiting, reaches 2 years.Because occurring upper right abdomen dull pain after feed Carnis Sus domestica, abdominal distention, singultus, vomiting.The light tenderness of upper right abdomen, does not touch gallbladder, Murphy's sign (+).Ultrasound diagnosis: gallbladder wall hair, thicken, visit and 3.0mm * 5.0mm stone-echo in capsule.Be diagnosed as caused by hepatic stagnation qi stagnation cholecystitis, cholelithiasis.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, and continues to take 3 courses for the treatment of, and symptom and sign disappears, B ultrasonic check: gallbladder normal in size, wall is smooth, does not visit and stone-echo recovery from illness in capsule, follows up a case by regular visits to without recurrence after half a year.
The specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated, and following this embodiment does not only limit the present invention for the present invention is described.
Embodiment 1, and a kind of Chinese medicine composition for the treatment of caused by hepatic stagnation qi stagnation cholecystitis is to be made by Celastrus aceleatus Merr 40g, Lignum et Radix Naucleae 20g, Flos jasmini 20g, Herba Aeluropi sinensis 20g, Pericarpium Citri junoris 10g, Rhizoma Chuanxiong 10g, Herba Menthae 10g, Semen Oroxyli 10g, Rhizoma Cyperi 10g, Fructus Akebiae 8g.
Embodiment 2, and a kind of Chinese medicine composition for the treatment of caused by hepatic stagnation qi stagnation cholecystitis is to be made by Celastrus aceleatus Merr 50g, Lignum et Radix Naucleae 30g, Flos jasmini 30g, Herba Aeluropi sinensis 30g, Pericarpium Citri junoris 20g, Rhizoma Chuanxiong 20g, Herba Menthae 20g, Semen Oroxyli 20g, Rhizoma Cyperi 20g, Fructus Akebiae 10g.
Embodiment 3, and a kind of Chinese medicine composition for the treatment of caused by hepatic stagnation qi stagnation cholecystitis is that Celastrus aceleatus Merr 60g, Lignum et Radix Naucleae 40g, Flos jasmini 40g, Herba Aeluropi sinensis 40g, Pericarpium Citri junoris 30g, Rhizoma Chuanxiong 30g, Herba Menthae 30g, Semen Oroxyli 30g, Rhizoma Cyperi 30g, Fructus Akebiae 12g make.
Claims (2)
1. treat a Chinese medicine composition for caused by hepatic stagnation qi stagnation cholecystitis, it is characterized in that it is to be made by following raw material medicaments:
Celastrus aceleatus Merr 40-60 part, Lignum et Radix Naucleae 20-40 part, Flos jasmini 20-40 part, Herba Aeluropi sinensis 20-40 part, 10-30 parts of Pericarpium Citri junoriss, 10-30 parts of Rhizoma Chuanxiongs, 10-30 parts of Herba Menthaes, 10-30 parts of Semen Oroxylis, 10-30 parts of Rhizoma Cyperis, 8-12 parts of Fructus Akebiaes.
2. Chinese medicine composition according to claim 1, is characterized in that it is to be made by following raw material medicaments:
50 parts of Celastrus aceleatus Merr, 30 parts of Lignum et Radix Naucleae, 30 parts of Flos jasmini, 30 parts of Herba Aeluropi sinensis, 20 parts of Pericarpium Citri junoriss, 20 parts of Rhizoma Chuanxiongs, 20 parts of Herba Menthaes, 20 parts of Semen Oroxylis, 20 parts of Rhizoma Cyperis, 10 parts of Fructus Akebiaes.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104547721A (en) * | 2015-02-05 | 2015-04-29 | 王昌荣 | Traditional Chinese medicine for treating cholecystitis |
| CN104721407A (en) * | 2015-04-01 | 2015-06-24 | 宁宁 | Traditional Chinese medicine composition for treating liver-depression and qi-stagnation type cholecystitis |
| CN105194513A (en) * | 2015-10-26 | 2015-12-30 | 烟台瑞智生物医药科技有限公司 | Traditional Chinese medicinal composition for treating liver depression and qi stagnation type hypochondriac pain |
| CN106107036A (en) * | 2016-06-28 | 2016-11-16 | 宿松飞翔生态养殖有限公司 | A kind of livestock fodder additives with epidemic prevention function |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101843882A (en) * | 2009-11-05 | 2010-09-29 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating cholecystitis diseases and preparation method thereof |
| CN102872270A (en) * | 2012-09-25 | 2013-01-16 | 朱风文 | Traditional Chinese medicine for treating chronic cholecystitis |
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2013
- 2013-09-23 CN CN201310464907.9A patent/CN103520531B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101843882A (en) * | 2009-11-05 | 2010-09-29 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating cholecystitis diseases and preparation method thereof |
| CN102872270A (en) * | 2012-09-25 | 2013-01-16 | 朱风文 | Traditional Chinese medicine for treating chronic cholecystitis |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104547721A (en) * | 2015-02-05 | 2015-04-29 | 王昌荣 | Traditional Chinese medicine for treating cholecystitis |
| CN104721407A (en) * | 2015-04-01 | 2015-06-24 | 宁宁 | Traditional Chinese medicine composition for treating liver-depression and qi-stagnation type cholecystitis |
| CN105194513A (en) * | 2015-10-26 | 2015-12-30 | 烟台瑞智生物医药科技有限公司 | Traditional Chinese medicinal composition for treating liver depression and qi stagnation type hypochondriac pain |
| CN106107036A (en) * | 2016-06-28 | 2016-11-16 | 宿松飞翔生态养殖有限公司 | A kind of livestock fodder additives with epidemic prevention function |
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| CN103520531B (en) | 2015-04-08 |
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