Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of bronchial asthma of child.The traditional Chinese medical science thinks, children's's lungs tissue development is perfect relatively not, and the spleen tending to insufficiency usually, the kidney being always deficient, cause spleen, lungs, renal function imbalance, thereby form phlegm retention in addition.When being invaded by exogenous pathogen, latent phlegm prolonged fluid-retention, phlegm rising following QI, obstruction of QI due to retention of phlegm, fights mutually sharp, obstructing airway, so that exhale inhale less, breath dyspnea with rapid and short breath, throat croup rale more.When outbreak, expectorant is with pneumatic, and obstruction of QI due to retention of phlegm, mutually wipes and hit, and obstructing airway, causes forming asthma.
The object of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment bronchial asthma of child is made by the Chinese medicine of following weight portion: Herba Seu Radix Peperomiae Tetraphyllae 3-6 part, Flos Fraxini Chinensis 2-4 part, Herba Thuniae Albae 4-6 part, Herb of Goering Lemongrass 7-9 part, Herba Cremanthodii plantaginei 7-9 part, Cortex Seu Radix Wikstroemiae Micranthae 5-7 part, Radix Delphinii Yunnanensis 4-6 part, Cortex Acanthopancis 7-9 part, Radix Fortunellae Margaritae 7-12 part, Herba Eragrostidis tenellae 4-7 part, Radix Inulae 6-10 part, Rhizoma Dioscoreae 9-12 part, Radix Glycyrrhizae 6-8 part.
Preferred: 4.5 parts of Herba Seu Radix Peperomiae Tetraphyllaes, 3 parts of Flos Fraxini Chinensiss, 5 parts of Herba Thuniae Albae, 8 parts of Herb of Goering Lemongrass, 8 parts of Herba Cremanthodii plantagineis, 6 parts of Cortex Seu Radix Wikstroemiae Micranthae, 5 parts, Radix Delphinii Yunnanensis, 8 parts of Cortex Acanthopanciss, 9.5 parts of Radix Fortunellae Margaritaes, 5.5 parts of Herba Eragrostidis tenellae, 8 parts of Radix Inulaes, 10.5 parts of Rhizoma Dioscoreaes, 7 parts, Radix Glycyrrhizae.
Preparation method: make decoction by traditional preparation method decocting.
In side: Herba Seu Radix Peperomiae Tetraphyllae: expelling wind and removing dampness, eliminating phlegm and stopping cough; Herb of Goering Lemongrass, Flos Fraxini Chinensis: cough-relieving, Dingchuan; Herba Thuniae Albae: relieving cough and asthma, blood circulation promoting and blood stasis dispelling; Herba Cremanthodii plantaginei: expelling phlegm for arresting cough, the chest stuffiness relieving promoting the circulation of QI; Cortex Seu Radix Wikstroemiae Micranthae: relieving cough and resolving phlegm; Radix Delphinii Yunnanensis, Cortex Acanthopancis: dispeiling pathogenic wind and removing dampness; Radix Fortunellae Margaritae: pleasant reducing phlegm; Herba Eragrostidis tenellae: moistening the lung and resolving phlegm, spleen invigorating QI invigorating; Radix Inulae: strengthening the spleen and nourishing the stomach, promoting the flow of QI for relieving the stagnancy; Rhizoma Dioscoreae: spleen reinforcing kidney, lung benefiting promotes the production of body fluid; Radix Glycyrrhizae: relieving cough and moistening lung, in QI invigorating benefit, coordinating the actions of various ingredients in a prescription
Clinical data
1. physical data is collected in January, the 2010~2,012 50 routine infants that year January, my institute accepted for medical treatment, is divided at random two groups, treatment group 25 examples, male 15 examples wherein, female's 10 examples, the infant age is at 3 years old~13 years old, average (8.57 ± 1.95) year; 9 routine parents of hospitalized children have allergies; Induced factor: 10 examples are respiratory tract infection, 5 examples are that cold air sucks, and 2 examples are dust contact, and 3 examples are pollen and seafood etc., and 5 routine infants are without obvious inducement.Matched group infant 25 examples, male 13 examples wherein, female's 12 examples, the infant age is at 4 years old~13 years old, average (8.84 ± 1.61) year; 11 routine parents of hospitalized children have allergies; Induced factor: 10 examples are respiratory tract infection, 6 examples are that cold air sucks, and 3 examples are dust contact, and 4 examples are pollen and seafood etc., and 3 routine infants are without obvious inducement.The no significant differences such as the sex of two groups of infants, age, family history and induced factor, P > 0.05, difference not statistically significant, has comparability.
2. diagnostic criteria: make a definite diagnosis according to " the Diagnosis of Children with Asthma standard " of national pediatric asthma cooperative groups formulation in 1993, and there is following characteristics: sudden onset, rapid breathing, gurgling with sputum, dysphoria, night are especially heavy, the fear of cold back of the body is cold, sneeze is frequent, watery nasal discharge is more than, clear and thin sputum or band foam, clear urine in large amounts, pale tongue with thin fur is white or greasy, stringy and thready pulse or slick and frivolous in vain, the visible short of breath of severe one, pale complexion, two bluish lip purples, dripping sweat.
3. all cases of Therapeutic Method all give the Comprehensive Treatments such as albuterol, hormone.On this basis, treatment group adds with prescription: take Herba Seu Radix Peperomiae Tetraphyllae 4.5g, Flos Fraxini Chinensis 3g, Herba Thuniae Albae 5g, Herb of Goering Lemongrass 8g, Herba Cremanthodii plantaginei 8g, Cortex Seu Radix Wikstroemiae Micranthae 6g, Radix Delphinii Yunnanensis 5g, Cortex Acanthopancis 8g, Radix Fortunellae Margaritae 9.5g, Herba Eragrostidis tenellae 5.5g, Radix Inulae 8g, Rhizoma Dioscoreae 10.5g, Radix Glycyrrhizae 7g, decocting becomes decoction, 50ml/ agent, each potion for oral administration of morning and evening, observe the curative effect after 3 weeks.
4. criterion of therapeutical effect is drafted with reference to Ministry of Public Health " new Chinese medicine guideline of clinical investigations ".Effective: asthma attack obviously alleviates before treating, pulmonary's wheezing sound disappears or before treatment, obviously alleviates.Effective: asthma attack alleviates before treating to some extent, two lung wheezing sounds are treated front obvious minimizing.Invalid: clinical symptoms sign, without improving or increasing the weight of.
5. curative effect comparison after two groups of treatments of therapeutic outcome, treatment group 25 examples: wherein effective: 15 examples, 60.0%; Effective: 8 examples, 32.0%; Invalid: 2 examples, 8.0%; Total effective rate: 92.0%; Matched group 25 examples: effective: 8 examples, 32.0%; Effective: 10 examples, 40.0%; Invalid: 7 examples, 28.0%; Total effective rate: 72.0%.
The specific embodiment
Embodiment mono-: Herba Seu Radix Peperomiae Tetraphyllae 4.5g, Flos Fraxini Chinensis 3g, Herba Thuniae Albae 5g, Herb of Goering Lemongrass 8g, Herba Cremanthodii plantaginei 8g, Cortex Seu Radix Wikstroemiae Micranthae 6g, Radix Delphinii Yunnanensis 5g, Cortex Acanthopancis 8g, Radix Fortunellae Margaritae 9.5g, Herba Eragrostidis tenellae 5.5g, Radix Inulae 8g, Rhizoma Dioscoreae 10.5g, Radix Glycyrrhizae 7g, make decoction by traditional preparation method decocting.
Embodiment bis-: Herba Seu Radix Peperomiae Tetraphyllae 3g, Flos Fraxini Chinensis 2g, Herba Thuniae Albae 4g, Herb of Goering Lemongrass 7g part, Herba Cremanthodii plantaginei 7g, Cortex Seu Radix Wikstroemiae Micranthae 5g, Radix Delphinii Yunnanensis 4g, Cortex Acanthopancis 7g, Radix Fortunellae Margaritae 7g, Herba Eragrostidis tenellae 4g, Radix Inulae 6g, Rhizoma Dioscoreae 9g, Radix Glycyrrhizae 6g, make decoction by traditional preparation method decocting.
Embodiment tri-: Herba Seu Radix Peperomiae Tetraphyllae 6g, Flos Fraxini Chinensis 4g, Herba Thuniae Albae 6g, Herb of Goering Lemongrass 9g, Herba Cremanthodii plantaginei 9g, Cortex Seu Radix Wikstroemiae Micranthae 7g, Radix Delphinii Yunnanensis 6g, Cortex Acanthopancis 9g, Radix Fortunellae Margaritae 12g, Herba Eragrostidis tenellae 7g, Radix Inulae 10g, Rhizoma Dioscoreae 12g, Radix Glycyrrhizae 8g, make decoction by traditional preparation method decocting.