CN103495078A - Traditional Chinese medicine for treating hyperplastic gonarthritis - Google Patents

Abstract

The invention relates to the field of pharmaceutical formulation, and particularly relates to a traditional Chinese medicine for treating hyperplastic gonarthritis. The traditional Chinese medicine is characterized by comprising the following raw materials by weight percent: 15-18% of rhizoma arisaematis, 10-13% of pericarpium zanthoxyli, 7-10% of kadsura pepper stem, 7-9% of cortex acanthopanacis, 6-9% of herba epimedii, 1-2% of semen coicis, 1-2 parts of eucommia ulmoides, 4-7% of large-leaved gentian, 5-8% of ground beeltle, 2-5% of spina gleditsiae, 3-5% of herba pyrolae, 4-6% of radices sileris, 4-6% of notopterygium root, 5-7% of fructus evodiae, 1-3% of radix paeoniae rubra, and 3-6% of myrrh; the 16 raw medicinal materials are baked and grinded into fine powder, and filtered by a 100-mesh sieve. The traditional Chinese medicine has the beneficial effects of being low in cost, especially significant in effect on the symptoms such as arthrocele, hydrops articuli and limitation of motion in hypertrophic arthritis, and free of toxic and side effects, and has the effects of promoting the circulation of qi, removing stasis, clearing and activating the channels and collaterals, dispelling wind, eliminating dampness, permeating bones, relieving muscles, relieving convulsion and easing pain.

Description

The Chinese medicine for the treatment of Knee Arthritis

Technical field

The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine for the treatment of Knee Arthritis.

Background technology

As everyone knows, kneed loosening of articular capsule weakness, the stability in joint mainly relies on ligament and muscle.The most important with medial collateral ligament, it has the two-layer fiber of the depth between internal epicondyle of femur and tuberosity of tibia,internal.Shallow-layer becomes trigonum, very tough and tensile, and deep layer fiber and joint capsule merge, and part also is connected with medial meniscus.Knee Arthritis is a kind of chronic joint disease that articular cartilage degeneration and Secondary cases hyperosteogeny be feature of take, and is more common in middle-aged and elderly people, and the women is more than the male.Be apt to occur in the positions such as knee joint that burden is larger.Its genesis is a kind of long-term, chronic, progressive pathological process, all if any cartilage nutrition, Developmental and Metabolic Disorder; The stress equilibrium imbalance of biomechanics aspect; Biochemical change; The abnormal Degradation of enzyme to cartilage matrix; The cumulative bad microtrauma; The factors such as obesity, joint load increase.Clinical cardinal symptom is pain, and the initial stage is slight dull pain, later progressively aggravation.When movable many, the pain increased, after having a rest, takes a turn for the better.Some patients feel pain to alleviate a little after activity when sitting quietly or while rising morning, are referred to as " rest pain ", but movable when excessive, because the articular surface friction also can produce pain.The pain factor such as can suffer from cold with Changes in weather, humidity is relevant.Patients with terminal is many with obvious synovial membrane inflammation, shows as that the pain increased, arthroncus, hydrarthrosis, limitation of activity.Physical examination, when hydrops is arranged, the floating patella test positive can appear in knee joint; Joint deformity appears in severe patient, as genu varum.X-ray checks: soft tissue swelling, and joint space narrows down in various degree, and the edge, joint has hyperosteogeny to form.Epiphysis distortion in late period, the articular surface out-of-flatness, the edge hyperosteogeny is obvious, under cartilage, has sclerosis and blister cavities to form, the fuzzy or disappearance of fat pad under kneecap during companion's synovitis.At present the medicine of clinical treatment Knee Arthritis is a lot of, but can only treat its disease, refractory its because of.Use anesthetis partial closure, pain can disappear in a short time, but easily outbreak repeatedly, prolonged application antipyretic-antalgic and hormone medicine are large and side effect is many to actual bodily harm.

Summary of the invention

Technical problem to be solved by this invention is in order to overcome the deficiencies in the prior art, a kind of Chinese medicine for the treatment of Knee Arthritis is provided, cost is low, especially to symptom successfuls such as the arthroncus in proliferative arthritis, hydrarthrosis, limitation of activity and have no side effect, there is the circulation of qi promoting silt that disappears, dredge the meridian passage, expelling wind and removing dampness, deep expelling pathogenic factors from muscles, relieving convulsion analgesia effect.

The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine for the treatment of Knee Arthritis, it is characterized in that, raw material forms, Rhizoma Arisaematis 15～18%, Fructus Zanthoxyli 10～13%, Caulis Piperis Kadsurae 7～10%, Cortex Acanthopancis 7～9%, Herba Epimedii 6～9%, Semen Coicis 1～2%, the Cortex Eucommiae 1～2%, Radix Gentianae Macrophyllae 4～7%, Eupolyphaga Seu Steleophaga 5～8%, Spina Gleditsiae 2～5%, Herba Pyrolae 3～5%, Radix Saposhnikoviae 4～6%, Rhizoma Et Radix Notopterygii 4～6%, Fructus Evodiae 5～7%, Radix Paeoniae Rubra 1～3%, Myrrha 3～6%, by above-mentioned 16 flavor crude drug, oven dry is ground and is ground into fine powder, cross 100 mesh sieves.

The invention has the beneficial effects as follows, cost is low, especially to the symptom successful such as the arthroncus in proliferative arthritis, hydrarthrosis, limitation of activity and have no side effect, has the circulation of qi promoting silt that disappears, dredge the meridian passage, expelling wind and removing dampness, deep expelling pathogenic factors from muscles, relieving convulsion analgesia effect.

The specific embodiment

Below in conjunction with embodiment, the invention will be further described:

Embodiment 1:

Adopting Rhizoma Arisaematis, Fructus Zanthoxyli, Caulis Piperis Kadsurae, Cortex Acanthopancis, Herba Epimedii, Semen Coicis, the Cortex Eucommiae, Radix Gentianae Macrophyllae, Eupolyphaga Seu Steleophaga, Spina Gleditsiae, Herba Pyrolae, Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, Fructus Evodiae, Radix Paeoniae Rubra, Myrrha is that raw material is prepared from.Every pair of its ingredient (% by weight) is Rhizoma Arisaematis 16.8, Fructus Zanthoxyli 12.6, Caulis Piperis Kadsurae 8.9, Cortex Acanthopancis 8.6, Herba Epimedii 7.5, Semen Coicis 1.4, the Cortex Eucommiae 1.5, Radix Gentianae Macrophyllae 4.8, Eupolyphaga Seu Steleophaga 7.2, Spina Gleditsiae 4.3, Herba Pyrolae 4.8, Radix Saposhnikoviae 4.8, Rhizoma Et Radix Notopterygii 4.8, Fructus Evodiae 5.8, Radix Paeoniae Rubra 1.9, Myrrha 4.3.Get above-mentioned 16 flavor Chinese herbal medicine gross weight 208 grams and dry, grind and be ground into fine powder, cross 100 mesh sieves, in the freshness protection package of packing into, put into the sterilization wide mouthed bottle, tighten bottleneck standby.Thin medicated powder end is poured in aseptic kidney basin, add the rice vinegar furnishing shape that falls apart, with having held, loose fist scatters, pack in the thin cotton thread cloth bag of good permeability, tie bag mouth, spread in the knee joint swelling, hydrops, surface, tenderness position of hypertrophy and pave and scatter, thick about 1cm left and right, then pack in the cotton thread cloth bag with the granule Sal of making popular, tie bag mouth, be pressed on medicated bag and pave, the pressure heat-preserving medicated bag, increase the osmosis of medicine, impel the space between skin and muscles dredging, venation is in harmonious proportion, and the QI and blood smoothness reaches the effect of circulation of qi promoting repercussive, expelling wind and removing dampness, deep expelling pathogenic factors from muscles, relieving convulsion analgesia.About 1 hour, each hot-wet compress medicated powder end, every day 2 times, after current fomentation medicine, can take off the Sal bag every night, and by the fixing wrapping of applying ointment or plaster for the medicine pockets of powder, take off inferior morning, 1 dose of every day.After applying 3 weeks, then use instead 1 time every night, apply 3 weeks, share about 6 weeks.

Rhizoma Arisaematis drying dampness to eliminate phlegm of the present invention, expelling wind and relieving convulsion, mass dissipating and swelling eliminating.For the pertinacious phlegm cough, dizziness due to wind-phlegm, middle wind-phlegm is stopped up, facial hemiparalysis, hemiplegia, epilepsy, infantile convulsion, tetanus.Give birth to and use external treatment carbuncle, snake bite and insect sting; Fructus Zanthoxyli acrid in the mouth, hot in nature, return spleen, stomach warp, and fragrant stomach invigorating is arranged, warming spleen and stomach for dispelling cold, removing damp and stopping pain, parasite killing removing toxic substances, the effect of antipruritic solution raw meat; The Caulis Piperis Kadsurae wind-damp dispelling, the meridian dredging, stopping numbness pain.For anemofrigid-damp arthralgia, arthrodynia of extremities, the contracture of muscle arteries and veins, joint stuffiness; Cortex Acanthopancis expelling wind and removing dampness, strong muscles and bones, liver and kidney tonifying, promoting blood circulation to remove obstruction in the collateral.Control the diseases such as arthralgia, soreness of waist and knee joint, physical weakness, traumatic injury; The Herba Epimedii acrid, sweet, warm.Return liver, kidney channel, kidney-replenishing is arranged, bone and muscle strengthening, the effect of wind-damp dispelling.Can be used for impotence and seminal emission, the muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture, climacteric hypertension; Semen Coicis is partially cold and cool, and promoting diuresis to eliminate damp pathogen is expert at most, can dry except wind, clearing away heat and discharging pus, eliminating impediment pain relieving, remarkable to dysuria, edema, beriberi and rheumatalgia texts; Cortex Eucommiae sweet in the mouth, warm in nature.Return liver, kidney, stomach warp.Liver and kidney tonifying, bone and muscle strengthening, Chong and Ren Meridians regulating, solid through antiabortive.The lumbago and skelalgia that the treatment insufficiency of kidney-YANG causes or aching and limp unable.Born of the same parents' tire that deficiency of liver-QI causes is not solid, the scrotum pruritus due to damp pathogen; Radix Gentianae Macrophyllae energy wind-damp dispelling, reducing the asthenic fever, pain relieving, cure mainly rheumatic arthritis, low grade fever, infantile malnutrition heating; Eupolyphaga Seu Steleophaga is cold in nature, salty in the mouth, poisonous, can enter conscience spleen three warps, has removing blood stasis, removing mass, dredging collateral, reason wound and reunion of bone, reducing swelling and alleviating pain, stimulating milk secretion is stimulated the menstrual flow etc.; Spina Gleditsiae is thought suffering by the traditional Chinese medical science, Wen De, and main effect is to draw out pus by applying a plaster to the affected part to dispel the wind, detumescence and apocenosis is mainly used on the dermatosis of health; The Herba Pyrolae tonify deficiency, kidney tonifying, expelling wind and removing dampness, promoting blood flow to regulate menstruation, for weakness cough, over-strained hemoptysis, rheumatic arthritis, metrorrhagia, leucorrhea, the cards such as traumatic hemorrhage; The Radix Saposhnikoviae expelling wind and cold, removing damp and stopping pain, the treatment headache, arthralgia, treatment tetanus, dispelling wind for relieving itching, separate the arsenic poison; The Rhizoma Et Radix Notopterygii cold expelling, dispel the wind, dehumidifying, pain relieving.For anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back; The contrary acid regurgitation of Fructus Evodiae stopping vomiting, headache due to JUE YIN disorder, the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, abdominal pain during menstruation, Diarrhoea, vascular hypertension, beriberi, hernia, aphthous ulcer, toothache, eczema; Radix Paeoniae Rubra has the functions such as clots absorbing, pain relieving, removing heat from blood, detumescence, controls that the stagnant amenorrhea of the stasis of blood, hernia abdominal mass gather, stomachache, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle, injury from falling down; Myrrha blood blood stasis removing, subduing swelling and relieving pain.Control traumatic injury, incised wound, muscles and bones, all pains of trusted subordinate, lump in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.The ingenious prescription of 16 flavor Chinese herbal medicine, the science compatibility: mutual reinforcement between, the mutual-assistance can be played synergism, can improve drug effect; Mutual restraint between two drugs, the mutual-detoxication can alleviate or eliminate toxic and side effects, the mutual coordinative role of medicine, the specially good effect of playing altogether " Knee Arthritis ".

Each raw material of the present invention embodiment that also but the listed ratio of according to the form below (percentage by weight) is mixed realizes.Its processing technique is identical with embodiment 1.

Below in conjunction with my institute, the clinical preliminary test that Hospital of Bone Setting, Wendeng City, Shandong Prov. carries out is done further, is described in detail the present invention:

1, case is selected: selected case is patient to our hospital in year February in June, 2006 to 2013.According to symptoms such as the gonalgia, swelling, hydrops, limitation of activity, in conjunction with physical examination and x ray examinations such as the floating patella test positive, genu varums, be diagnosed as hypertrophy knee joint patient's 63 examples altogether, male 29 examples, female's 34 examples; Age 47-72 is between year, course of disease 3-9.

2, diagnostic criteria: " the disease of tcm Standardization of diagnosis and curative effect " promulgated according to State Administration of Traditional Chinese Medicine.

3, Therapeutic Method: powder of the present invention is poured in aseptic kidney basin, add meter misadjustment to become a loose shape, with having held, loose fist scatters and is advisable, in the thin cotton thread cloth bag of the good permeability of packing into, tie bag mouth, spread in the knee joint swelling, hydrops, surface, tenderness position of hypertrophy, pave and scatter, thick about 1cm left and right, test in the cotton thread cloth bag of packing into and tie bag mouth with the granule of making popular again, be pressed on medicated bag and pave, the pressure heat-preserving medicated bag, increase the osmosis of medicine.Each hot compress medicated powder, about 1 hour, every day twice, can take off after salt bag pressurization hot compress every night, the medicine pockets of powder is fixed to wrapping with applying ointment or plaster, and take off morning next day, every day potion.After applying three weeks, then use instead every night once, apply three weeks, totally six weeks.

4, the standard of curative effect evaluation: it is effectively total effective rate that produce effects adds.

Produce effects: the clinical symptoms sign disappears, straight-leg raising test > 85 °, can recover normally on foot.

Effectively: the most of disappearance of clinical symptoms sign, straight-leg raising test > 60 ° of activities are slightly limited, substantially can adhere to normal walking.

Invalid: the clinical symptoms sign is not improved, and normal walking can not be adhered in straight-leg raising test<50 °.

5, therapeutic effect: use the present invention's 63 examples " hypertrophy knee joint " patient, apply 6 weeks and carry out therapeutic evaluation: produce effects 27 examples, effective 29 examples, invalid 7 examples, total effective rate is 88.9%.

Claims (1)

1. a Chinese medicine for the treatment of Knee Arthritis, it is characterized in that: the raw material composition is by weight percentage, Rhizoma Arisaematis 15～18%, Fructus Zanthoxyli 10～13%, Caulis Piperis Kadsurae 7～10%, Cortex Acanthopancis 7～9%, Herba Epimedii 6～9%, Semen Coicis 1～2%, the Cortex Eucommiae 1～2%, Radix Gentianae Macrophyllae 4～7%, Eupolyphaga Seu Steleophaga 5～8%, Spina Gleditsiae 2～5%, Herba Pyrolae 3～5%, Radix Saposhnikoviae 4～6%, Rhizoma Et Radix Notopterygii 4～6%, Fructus Evodiae 5～7%, Radix Paeoniae Rubra 1～3%, Myrrha 3～6%, by above-mentioned 16 flavor crude drug, oven dry is ground and is ground into fine powder, crosses 100 mesh sieves.