CN103495077B - Chinese medicine composition for treating urinary calculus - Google Patents
Chinese medicine composition for treating urinary calculus Download PDFInfo
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- CN103495077B CN103495077B CN201310467185.2A CN201310467185A CN103495077B CN 103495077 B CN103495077 B CN 103495077B CN 201310467185 A CN201310467185 A CN 201310467185A CN 103495077 B CN103495077 B CN 103495077B
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Abstract
The invention discloses a Chinese medicine composition for treating urinary calculus. The Chinese medicine believes that the urinary calculus disease belongs to the domains of stranguria and lumbago; dampness, heat, stasis and calculus are main features of the disease; stasis and calculus also are pathological products. According to the Chinese medicine composition, the traditional Chinese medicines, such as spicate clerodendranthus herb, nervilia fordii schltr, coix lachryma-jobi, waternut herb, daghestan sweetclover herb, lygodium japonicum, siberian elm bark, caudate milkwort root, solanum xanthocarpum, ceratostigma willmottianum, securidaca inappendiculata hassk, saruma root and elecampane, with the effects of clearing heat and removing dampness, inducing diuresis for treating stranguria, dispersing blood stasis and removing urinary calculus, are selected to be decocted into decoction by water. The total effective rate of a treatment group is 97.8% and much better than 78.9% of a control group by a clinical test.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine composition for the treatment of urinary system calculus.
Background technology
Urinary system calculus is the commonly encountered diseases of urinary system.Calculus is found in any position of kidney, bladder, ureter and urethra.But be common with kidney and ureteral calculus.Clinical manifestation has different because position, calculus place is different.The Therapeutic Method of primary disease has multiple, but for calculus diameter <1.0cm person, evident in efficacy with Chinese medicine, low price, patient is easy to accept.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of urinary system calculus.Chinese medicine thinks that primary disease belongs to stranguria, lumbago category, the damp and hot sum eating and drinking without temperance of a specified duration of the multifactor body of primary disease, addicted to the product of the pungent savoury of food delicious food, subimbition in addition, damp-heat in lower-JIAO accumulates steaming, pent up bladder, make bladder qi dysfunction, disturbance in water passage, pyrogenicity is burnt wet poly-, and damp and hot accumulateing for a long time decocts urine, accumulate over a long period, accumulation of impurities Cheng Shi in urine.Wet, heat, the stasis of blood, stone are its principal characters, and the stasis of blood and stone are again its pathological product.Treatment is worked as with clearing away heat-damp and promoting diuresis, inducing diuresis for treating stranguria syndrome, blood stasis dispelling calculus for method.
The object of the invention is to be achieved through the following technical solutions, the Chinese medicine composition of this treatment urinary system calculus is made up of the Chinese medicine of following weight portion: Herba clerodendranthi spicati 30-35 part, Folium Nerviliae fordii 15-25 part, Radix Coicis 12-18 part, Herba Eleocharitis 14-22 part, Herba Meliloti Suaveolentis 18-24 part, Spora Lygodii 12-26 part, Cortex ulmi pumilae 5-15 part, Radix Polygalae Caudatae 15-20 part, Fructus solani xanthocarpi 15-18 part, Radix ceratostigmatis willemottiani 4-5 part, Radix securidacae 7-13 part, Radix Sarumatis henryi 5-10 part, Radix Inulae 5-14 part.
Preferred: Herba clerodendranthi spicati 33 parts, Folium Nerviliae fordii 20 parts, Radix Coicis 15 parts, Herba Eleocharitis 17 parts, Herba Meliloti Suaveolentis 21 parts, Spora Lygodii 19 parts, Cortex ulmi pumilae 10 parts, Radix Polygalae Caudatae 17 parts, Fructus solani xanthocarpi 16 parts, Radix ceratostigmatis willemottiani 4.5 parts, Radix securidacae 10 parts, Radix Sarumatis henryi 7.5 parts, Radix Inulae 9 parts.
Preparation method: above-mentioned Chinese medicine decocting is made decoction.
Fang Zhong: Herba clerodendranthi spicati, Herba Eleocharitis calculus diuretic, clearing away heat-damp and promoting diuresis; Folium Nerviliae fordii heat clearing away, dissipating blood stasis, removing toxic substances; Radix Coicis, Herba Meliloti Suaveolentis heat clearing away, removing toxic substances, removing dampness; Spora Lygodii, Cortex ulmi pumilae, Radix Polygalae Caudatae heat-clearing and toxic substances removing, relieving stranguria by diuresis; Fructus solani xanthocarpi clearing away heat-damp and promoting diuresis, repercussive pain relieving; Radix ceratostigmatis willemottiani promoting blood circulation and stopping pain, blood stasis dispersing and fresh blood promoting; Radix securidacae promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain, clearing away heat and promoting diuresis; Radix Sarumatis henryi, Radix Inulae regulating QI to relieve pain.
Clinical data
1. physical data case all derives from my Out-patient Department and inpatient totally 180 examples, wherein 150 examples have the symptom such as waist abdomen pain and paruria in various degree, waist stomachache show as paroxysmal aggravation and to lower abdomen and perineal position radiating pain, or with Nausea and vomiting, be in a cold sweat; 30 routine symptoms are not obvious, in health check-up, find lithangiuria.All cases is all taken the photograph sheet or intravenous urography or CT scan through B ultrasonic or abdominal X-ray and is diagnosed as urinary system calculus.Stone location: renal calculus 81 example, ureteral calculus 53 example, vesical calculus 6 example, calculus of urethra 10 example; Calculus transverse diameter is greater than 0.5cm and is less than 0.8cm, and vertical footpath is greater than 0.6cm and is less than 1.0cm.180 routine patients are divided into treatment group and matched group by complete randomized.Treatment group 90 example, man 60 example, female 30 example; 19 ~ 63 years old age, average 35.6 years old; Average 1.6 years of the course of disease.Matched group 90 example, man 61 example, female 29 example; 21 ~ 66 years old age, average 37.5 years old; Average 1.2 years of the course of disease.2 groups of sexes, age, courses of disease etc. compare, and difference there are no significant meaning (P>0.05), has comparability.
2. diagnostic criteria (1) clinical symptoms majority has side or bilateral waist and belly rest pain, paroxysmal colic, with or do not accompany the symptoms such as Nausea and vomiting, hematuria, frequent micturition, urgent micturition; (2) urine microscopy has erythrocyte or the occult blood positive; (3) ultrasonic and x-ray abdomen plain film or renal phlebography show calculus image or light, moderate hydronephrosis, without obvious renal function injury, without urinary tract deformity.
3. Therapeutic Method treatment group takes Chinese medicine preparation of the present invention, take Herba clerodendranthi spicati 33g, Folium Nerviliae fordii 20g, Radix Coicis 15g, Herba Eleocharitis 17g, Herba Meliloti Suaveolentis 21g, Spora Lygodii 19g, Cortex ulmi pumilae 10g, Radix Polygalae Caudatae 17g, Fructus solani xanthocarpi 16g, Radix ceratostigmatis willemottiani 4.5g, Radix securidacae 10g, Radix Sarumatis henryi 7.5g, Radix Inulae 9g, decocting becomes decoction, potion, divided and sooner or later took for 2 times every day.Matched group takes uralyt (German Warsaw pharmaceutical factory produces, and China imports and exports No. X960447, drug registration card, No. 1014886th, China trademark registration certificate), each 2, every day 2 times.Two groups equal 7 days be 1 course for the treatment of, serve on 3 courses for the treatment of.
4. criterion of therapeutical effect is with reference to efficacy assessment standard in " disease of tcm Standardization of diagnosis and curative effect ".Cure: calculus is discharged, clinical symptom disappearance, ultrasonic or x-ray check calculus disappears.Effective: clinical symptom disappearance, ultrasonic or x-ray check calculus reduces or moves down, or hydronephrosis disappears.Invalid: clinical symptoms is not improved, calculus quantity, size, position are without change, and hydronephrosis is without improvement.
5. cure 69 examples in therapeutic outcome treatment group 90 example, account for 76.7%, effective 19 examples, account for 21.1%, and invalid 2 examples, account for 2.2%, total effective rate 97.8%; Cure 25 examples in matched group 90 example, account for 27.8%, effective 46 examples, account for 51.1%, and invalid 19 examples, account for 21.1%, total effective rate 78.9%, treatment group curative effect is obviously better than matched group, two groups of difference significances.P<0.05。
Detailed description of the invention
Embodiment one: take Herba clerodendranthi spicati 33g, Folium Nerviliae fordii 20g, Radix Coicis 15g, Herba Eleocharitis 17g, Herba Meliloti Suaveolentis 21g, Spora Lygodii 19g, Cortex ulmi pumilae 10g, Radix Polygalae Caudatae 17g, Fructus solani xanthocarpi 16g, Radix ceratostigmatis willemottiani 4.5g, Radix securidacae 10g, Radix Sarumatis henryi 7.5g, Radix Inulae 9g, makes decoction by above-mentioned Chinese medicine decocting.
Embodiment two: take Herba clerodendranthi spicati 33g, Folium Nerviliae fordii 25g, Radix Coicis 18g, Herba Eleocharitis 22g, Herba Meliloti Suaveolentis 24g, Spora Lygodii 26g, Cortex ulmi pumilae 15g, Radix Polygalae Caudatae 20g, Fructus solani xanthocarpi 15g, Radix ceratostigmatis willemottiani 5g, Radix securidacae 13g, Radix Sarumatis henryi 10g, Radix Inulae 14g, makes decoction by above-mentioned Chinese medicine decocting.
Embodiment three: take Herba clerodendranthi spicati 35g, Folium Nerviliae fordii 15g, Radix Coicis 12g, Herba Eleocharitis 14g, Herba Meliloti Suaveolentis 18g, Spora Lygodii 12g, Cortex ulmi pumilae 5g, Radix Polygalae Caudatae 15g, Fructus solani xanthocarpi 18g, Radix ceratostigmatis willemottiani 4g, Radix securidacae 7g, Radix Sarumatis henryi 5g, Radix Inulae 5g, makes decoction by above-mentioned Chinese medicine decocting.
Claims (2)
1. treat a Chinese medicine composition for urinary system calculus, it is characterized in that this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Herba clerodendranthi spicati 30-35 part, Folium Nerviliae fordii 15-25 part, Radix Coicis 12-18 part, Herba Eleocharitis 14-22 part, Herba Meliloti Suaveolentis 18-24 part, Spora Lygodii 12-26 part, Cortex ulmi pumilae 5-15 part, Radix Polygalae Caudatae 15-20 part, Fructus solani xanthocarpi 15-18 part, Radix ceratostigmatis willemottiani 4-5 part, Radix securidacae 7-13 part, Radix Sarumatis henryi 5-10 part, Radix Inulae 5-14 part.
2. a kind of Chinese medicine composition for the treatment of urinary system calculus according to claim 1, is characterized in that this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Herba clerodendranthi spicati 33 parts, Folium Nerviliae fordii 20 parts, Radix Coicis 15 parts, Herba Eleocharitis 17 parts, Herba Meliloti Suaveolentis 21 parts, Spora Lygodii 19 parts, Cortex ulmi pumilae 10 parts, Radix Polygalae Caudatae 17 parts, Fructus solani xanthocarpi 16 parts, Radix ceratostigmatis willemottiani 4.5 parts, Radix securidacae 10 parts, Radix Sarumatis henryi 7.5 parts, Radix Inulae 9 parts.
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| CN104971221A (en) * | 2015-08-10 | 2015-10-14 | 孙霞 | Traditional Chinese medicine for treating lithiasis in urinary system |
| CN105434967A (en) * | 2016-01-13 | 2016-03-30 | 孟祥来 | Traditional Chinese medicine decoction for treating urethral calculus |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101590194A (en) * | 2008-05-26 | 2009-12-02 | 高庆保 | Traditional Chinese medicine for treating urinary calculus |
| CN102078527A (en) * | 2010-12-16 | 2011-06-01 | 江鹏 | Traditional Chinese medicine formula for treating urinary calculus |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101590194A (en) * | 2008-05-26 | 2009-12-02 | 高庆保 | Traditional Chinese medicine for treating urinary calculus |
| CN102078527A (en) * | 2010-12-16 | 2011-06-01 | 江鹏 | Traditional Chinese medicine formula for treating urinary calculus |
Non-Patent Citations (1)
| Title |
|---|
| 中医治疗尿石症概况;王贤;《中国实用医药》;20080610(第16期);188，189 * |
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