CN103494988B - 一种治疗不孕症的中药组合物 - Google Patents
一种治疗不孕症的中药组合物 Download PDFInfo
- Publication number
- CN103494988B CN103494988B CN201210086439.1A CN201210086439A CN103494988B CN 103494988 B CN103494988 B CN 103494988B CN 201210086439 A CN201210086439 A CN 201210086439A CN 103494988 B CN103494988 B CN 103494988B
- Authority
- CN
- China
- Prior art keywords
- parts
- infertility
- radix
- powder
- chinese medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 208000000509 infertility Diseases 0.000 title claims abstract description 16
- 230000036512 infertility Effects 0.000 title claims abstract description 16
- 231100000535 infertility Toxicity 0.000 title claims abstract description 16
- 239000000203 mixture Substances 0.000 title claims abstract description 16
- 239000003814 drug Substances 0.000 title claims abstract description 14
- 239000000843 powder Substances 0.000 claims abstract description 18
- 241000628997 Flos Species 0.000 claims abstract description 13
- 241000283026 Cervus elaphus Species 0.000 claims abstract description 12
- 241000756943 Codonopsis Species 0.000 claims abstract description 11
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 11
- 210000000582 semen Anatomy 0.000 claims abstract description 11
- 239000002775 capsule Substances 0.000 claims abstract description 10
- 239000003826 tablet Substances 0.000 claims abstract description 10
- 239000008280 blood Substances 0.000 abstract description 16
- 210000004369 blood Anatomy 0.000 abstract description 15
- 230000007812 deficiency Effects 0.000 abstract description 10
- 230000006378 damage Effects 0.000 abstract description 5
- 230000000694 effects Effects 0.000 abstract description 4
- 238000004080 punching Methods 0.000 abstract description 4
- 210000003734 kidney Anatomy 0.000 abstract description 3
- 231100000957 no side effect Toxicity 0.000 abstract description 3
- 210000004291 uterus Anatomy 0.000 abstract description 3
- 208000024891 symptom Diseases 0.000 abstract description 2
- 208000002193 Pain Diseases 0.000 description 10
- 238000000034 method Methods 0.000 description 10
- 230000036407 pain Effects 0.000 description 10
- 208000021267 infertility disease Diseases 0.000 description 7
- 201000000736 Amenorrhea Diseases 0.000 description 5
- 206010001928 Amenorrhoea Diseases 0.000 description 5
- 210000001015 abdomen Anatomy 0.000 description 5
- 231100000540 amenorrhea Toxicity 0.000 description 5
- 210000000481 breast Anatomy 0.000 description 5
- 210000004185 liver Anatomy 0.000 description 5
- 208000004998 Abdominal Pain Diseases 0.000 description 4
- 208000005171 Dysmenorrhea Diseases 0.000 description 4
- 206010013935 Dysmenorrhoea Diseases 0.000 description 4
- 208000019255 Menstrual disease Diseases 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 239000012535 impurity Substances 0.000 description 4
- 206010037660 Pyrexia Diseases 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- 206010010774 Constipation Diseases 0.000 description 2
- 208000019802 Sexually transmitted disease Diseases 0.000 description 2
- 208000031971 Yin Deficiency Diseases 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 238000005202 decontamination Methods 0.000 description 2
- 230000003588 decontaminative effect Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 206010025482 malaise Diseases 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 230000035935 pregnancy Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 208000002881 Colic Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 208000010228 Erectile Dysfunction Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 208000031361 Hiccup Diseases 0.000 description 1
- 206010021118 Hypotonia Diseases 0.000 description 1
- 208000019914 Mental Fatigue Diseases 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 206010029240 Neuritis Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010041497 Spermatorrhoea Diseases 0.000 description 1
- 206010043458 Thirst Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 206010000210 abortion Diseases 0.000 description 1
- 231100000176 abortion Toxicity 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 230000001166 anti-perspirative effect Effects 0.000 description 1
- 239000003213 antiperspirant Substances 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 230000035606 childbirth Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 230000035558 fertility Effects 0.000 description 1
- 208000017561 flaccidity Diseases 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 208000023513 hiccough Diseases 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 210000004914 menses Anatomy 0.000 description 1
- 201000001119 neuropathy Diseases 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
一种治疗不孕症的中药组合物，其组合配方按照质量配比选用为：白芍7.3-8.8份、川穹2.3-3.6份、红花2.1-3.7份、桃仁2.7-4.2份、泽兰2.9-4.3份、生地7.8-9.8份、香附2.9-4.4份、马鹿茸0.42-0.55份、党参0.46-0.58份。将按此成分配比的粉状物制成散剂或片剂或胶囊，能够有效得治疗女子肾虚、精亏血少、胞宫虚寒、冲任不足等症状，疗效确切可靠，而且无毒副作用，成本低，制作简单，使用安全方便。
Description
所属领域
本发明涉及一种不孕症的组方，具体说是一种用中草药制配的治疗不孕症的组合物。
背景技术
不孕症是指婚后同居，有正常性生活，未避孕达1年以上而未能怀孕者。根据婚后是否受过孕又可分为原发性不孕和继发性不孕。原发性不孕指从未妊娠过；继发性不孕指曾有过妊娠，以后1年以上未避孕而未再妊娠。根据不孕的原因可分为相对不孕和绝对不孕：相对不孕是指夫妇一方因某种原因阻碍受孕或使生育力降低，导致暂时性不孕，如该因素得到纠正，仍有可能怀孕。
不孕症发病率呈明显上升趋势，全世界的不孕患者人数约为8000万～1.1亿。不孕症发病率的递增趋势可能与晚婚晚育、人工流产、性传播疾病、生活压力大、作息不规律等相关。
发明内容
本发明的目的在于，提供一种治疗不孕症的中药组合物，它疗效确切可靠，而且无毒副作用，制作简单，使用安全方便。
按照中医学理论，女子不孕多以肾虚、精亏血少、胞宫虚寒、冲任不足所致。本发明基于祖国医学对女性不孕症的认识和对多种中草药药性的认识，通过药物品种组配，使本发明具有良好的功效。
本发明的组合配方按照质量配比选用如下：
白芍7.3-8.8份、川穹2.3-3.6份、红花2.1-3.7份、桃仁2.7-4.2份、泽兰2.9-4.3份、生地7.8-9.8份、香附2.9-4.4份、马鹿茸0.42-0.55份、党参0.46-0.58份。
本发明中的技术方案是：对本发明中各味中药进行提取，浓缩成稠膏，干燥成提取物干粉后，通过分别放入不同辅料，可制成胶囊剂、片剂和颗粒剂。
最佳组配比(质量)：白芍7.8份、川穹3.2份、红花2.9份、桃仁3.3份、泽兰3.7份、生地9.3份、香附3.4份、马鹿茸0.48份、党参0.52份。
本发明不限制成药的型状；本发明的组合物是人体可以接受的口服剂量。
白芍：养血柔肝，缓中止痛，敛阴收汗。治胸腹胁肋疼痛，泻痢腹痛，自汗盗汗，阴虚发热，月经不调，崩漏，带下。
炮制方法：为原药去杂质，润透切片，生用入药。
川穹：归肝胆经，能够活血行气，治疗血瘀气滞诸痛证。可以治疗气滞血瘀之胸胁、腹部诸痛；肝郁气滞之胁痛；心脉瘀阻之胸痹心痛；肝血瘀阻，积聚痞块、胸胁刺痛；跌仆损伤，瘀肿疼痛；血瘀经闭，产后恶漏不下，月经不调，寒凝血滞，难产，胞衣不下。
炮制方法：除去杂质，分开大小，略泡，洗净，润透，切薄片，干燥。
红花：活血通径、散瘀止痛。用于经闭、痛经、恶露不行、症瘕痞块、跌打损伤。古人常有於血在体内时，常加红花一小把。纱布包煮开可用一天两次泡脚，适用各种静脉曲张，末梢神经炎，血液循环不好，腿脚麻木或青紫等淤血症。
炮制方法：采回的红花，放阴凉处阴干，也可用文火焙干，温度控制在45℃以下，未干时不能堆放，以免发霉变质。
桃仁：活血祛瘀，润肠通便，止咳平喘。用于经闭，痛经，癓瘕痞块，跌扑损伤，肠燥便秘。
炮制方法：除去杂质。用时捣碎。
泽兰：活血化瘀，行水消肿。用于月经不调，经闭，痛经，产后瘀血腹痛，水肿。炮制方法：除去杂质，略洗，润透，切段，干燥。
生地：清热凉血，养阴，生津。用于热病舌绛烦渴，阴虚内热，骨蒸劳热，内热消渴，吐血，衄血，发斑发疹。
炮制方法：将地黄切成小块或片干燥成生地。
香附：理气解郁，调经止痛。用于肝郁气滞，胸、胁、脘腹胀痛，消化不良，月经不调，经闭痛经，寒疝腹痛，乳房胀痛。
炮制方法：拣去杂质，碾成碎粒，簸去细毛及细末。
马鹿茸：壮肾阳，益精血，强筋骨，调冲任，托疮毒。用于阳痿滑精，宫冷不孕，赢瘦，神疲，畏寒，眩晕，耳鸣耳聋，腰脊冷痛，筋骨痿软，崩漏带下，阴疽不敛。
炮制方法：夏、秋几季锯取鹿茸，马鹿长茸起、至53天之内采茸为最佳，经加工后，阴干或烘干，最好的加工工艺是冻干。
党参：补中益气，健脾益肺。用于脾肺虚弱，气短心悸，食少便溏，虚喘咳嗽，内热消渴。
炮制方法：取原药材，除去杂质，洗净，润透，切厚片，干燥。
本发明的有益效果是，能够有效得治疗女子肾虚、精亏血少、胞宫虚寒、冲任不足等症状，疗效确切可靠，而且无毒副作用，成本低，制作简单，使用安全方便。
具体实施方式
本发明中的技术方案是：对本发明中各味中药进行提取，浓缩成稠膏，干燥成提取物干粉后，通过分别放入不同辅料，可制成胶囊剂、片剂和颗粒剂。
实施例一
本发明的组合配方按照质量配比为：白芍7.5份、川穹3.2份、红花2.8份、桃仁3.1份、泽兰3.7份、生地8.2份、香附3.3份、马鹿茸0.46份、党参0.52份。将按此成分配比的粉状物制成散剂或片剂或胶囊。
实施例二
本发明的组合配方按照质量配比为：白芍8.3份、川穹2.6份、红花2.6份、桃仁3.4份、泽兰3.7份、生地9.5份、香附3.9份、马鹿茸0.48份、党参0.56份。将按此成分配比的粉状物制成散剂或片剂或胶囊。
实施例三
本发明的组合配方按照质量配比为：白芍8.6份、川穹2.9份、红花2.7份、桃仁3.7份、泽兰3.8份、生地8.6份、香附3.7份、马鹿茸0.49份、党参0.53份。将按此成分配比的粉状物制成散剂或片剂或胶囊。
实施例四
本发明的组合配方按照质量配比为：白芍8.2份、川穹3.1份、红花2.9份、桃仁3.4份、泽兰3.7份、生地9.6份、香附4.2份、马鹿茸0.44份、党参0.49份。将按此成分配比的粉状物制成散剂或片剂或胶囊。
实施例五
本发明的组合配方按照质量配比为：白芍7.6份、川穹2.5份、红花2.8份、桃仁3.8份、泽兰3.6份、生地9.1份、香附4.2份、马鹿茸0.52份、党参0.47份。将按此成分配比的粉状物制成散剂或片剂或胶囊。
Claims (2)
1.一种治疗不孕症的中药组合物，其特征在于：组合配方按照质量配比选用为：白芍7.3-8.8份、川芎2.3-3.6份、红花2.1-3.7份、桃仁2.7-4.2份、泽兰2.9-4.3份、生地7.8-9.8份、香附2.9-4.4份、马鹿茸0.42-0.55份、党参0.46-0.58份；将按此成分配比的粉状物制成散剂或片剂或胶囊。
2.根据权利要求1所述的一种治疗不孕症的中药组合物，其特征在于：其最佳组配比按照质量配比选用为：白芍7.8份、川芎3.2份、红花2.9份、桃仁3.3份、泽兰3.7份、生地9.3份、香附3.4份、马鹿茸0.48份、党参0.52份；将按此成分配比的粉状物制成散剂或片剂或胶囊。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210086439.1A CN103494988B (zh) | 2012-03-29 | 2012-03-29 | 一种治疗不孕症的中药组合物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210086439.1A CN103494988B (zh) | 2012-03-29 | 2012-03-29 | 一种治疗不孕症的中药组合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103494988A CN103494988A (zh) | 2014-01-08 |
| CN103494988B true CN103494988B (zh) | 2015-11-25 |
Family
ID=49860311
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210086439.1A Expired - Fee Related CN103494988B (zh) | 2012-03-29 | 2012-03-29 | 一种治疗不孕症的中药组合物 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103494988B (zh) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1356139A (zh) * | 2001-09-27 | 2002-07-03 | 孔金立 | 一种主治女性不孕症及其性功能障碍的药物 |
| CN1449776A (zh) * | 2002-04-09 | 2003-10-22 | 王泽淇 | 一种治疗不孕症的中药配方 |
| CN1526439A (zh) * | 2003-09-23 | 2004-09-08 | 邢文照 | 治疗妇女不孕症的中药及其制备方法和用途 |
| CN101099811A (zh) * | 2007-07-12 | 2008-01-09 | 尹克华 | 治疗女性不孕症的中药 |
| CN101274051A (zh) * | 2007-03-27 | 2008-10-01 | 海丝克（河南）生物科技有限公司 | 一种治疗不孕症胶囊的组配方法及制作工艺 |
| CN101152392B (zh) * | 2007-09-24 | 2010-06-02 | 雷兴福 | 一种治疗妇女不孕症的中药组合物 |
-
2012
- 2012-03-29 CN CN201210086439.1A patent/CN103494988B/zh not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1356139A (zh) * | 2001-09-27 | 2002-07-03 | 孔金立 | 一种主治女性不孕症及其性功能障碍的药物 |
| CN1449776A (zh) * | 2002-04-09 | 2003-10-22 | 王泽淇 | 一种治疗不孕症的中药配方 |
| CN1526439A (zh) * | 2003-09-23 | 2004-09-08 | 邢文照 | 治疗妇女不孕症的中药及其制备方法和用途 |
| CN101274051A (zh) * | 2007-03-27 | 2008-10-01 | 海丝克（河南）生物科技有限公司 | 一种治疗不孕症胶囊的组配方法及制作工艺 |
| CN101099811A (zh) * | 2007-07-12 | 2008-01-09 | 尹克华 | 治疗女性不孕症的中药 |
| CN101152392B (zh) * | 2007-09-24 | 2010-06-02 | 雷兴福 | 一种治疗妇女不孕症的中药组合物 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103494988A (zh) | 2014-01-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103656041B (zh) | 一种治疗宫颈癌的中药 | |
| CN102772779B (zh) | 一种治疗痛经的药物及其制备方法 | |
| CN103251792A (zh) | 一种治疗缺乳肝气郁结症的药物及其制备方法 | |
| CN104069317A (zh) | 一种助孕汤 | |
| CN102935205B (zh) | 一种治疗乳腺增生的中药组合物 | |
| CN104491144A (zh) | 一种治疗不孕不育妇科疾病的中药组合物 | |
| CN103690900B (zh) | 一种治疗功能性子宫出血的中药 | |
| CN105012430A (zh) | 一种治疗坐骨神经病痛的药物及其制备方法 | |
| CN103494988B (zh) | 一种治疗不孕症的中药组合物 | |
| CN101703624B (zh) | 一种治疗强直性脊柱炎的中药组合物 | |
| CN103816238B (zh) | 治疗甲状腺肿的中药 | |
| CN105999110A (zh) | 一种用于治疗女性慢性盆腔疼痛的中药冲剂及制备方法 | |
| CN101947303B (zh) | 一种根治高血压的药物及其制备方法 | |
| CN104352709A (zh) | 一种治疗胃溃疡的药物及其制备方法 | |
| CN103690880A (zh) | 一种治疗痛经的中药配方 | |
| CN102688453A (zh) | 一种治疗乳腺癌的中药组合物 | |
| CN102327510A (zh) | 治疗肝肾阴亏便秘的中草药 | |
| CN104758598A (zh) | 一种治疗闭经症的中药 | |
| CN104922409A (zh) | 一种治疗慢性宫颈炎的中药 | |
| CN101199782B (zh) | 一种内服用于治疗月经不调的中药组合物 | |
| CN104840726A (zh) | 一种可有效治疗席汉氏综合征的汤剂药物及制备方法 | |
| CN104042844A (zh) | 一种补肾调气汤 | |
| CN104873935A (zh) | 温肾养肝中药酒 | |
| CN104491719A (zh) | 一种治疗宫颈癌的中药组合物 | |
| CN104623339A (zh) | 一种治疗女性更年期综合症的中药 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| DD01 | Delivery of document by public notice |
Addressee: Sun Xiaowei Document name: Notification that Application Deemed not to be Proposed |
|
| C56 | Change in the name or address of the patentee | ||
| CP03 | Change of name, title or address |
Address after: 471125 No. 158 Luo Chang Road, Henan, Luoyang Patentee after: Henan Health Care Biological Technology Co., Ltd. Address before: Henan province office building 471003 Luoyang Xigong Valley Road Lingyu 2 floor North Patentee before: Haisike (Henan) Biological Sci-Tech Co., Ltd. |
|
| PP01 | Preservation of patent right | ||
| PP01 | Preservation of patent right |
Effective date of registration: 20180425 Granted publication date: 20151125 |
|
| DD01 | Delivery of document by public notice |
Addressee: Henan Health Care Biological Technology Co., Ltd. Document name: Notification of Decision on Request for Restoration of Right |
|
| DD01 | Delivery of document by public notice | ||
| PD01 | Discharge of preservation of patent |
Date of cancellation: 20210425 Granted publication date: 20151125 |
|
| PD01 | Discharge of preservation of patent | ||
| DD01 | Delivery of document by public notice |
Addressee: Sun Xiaowei Document name: Notice of termination of proceedings Addressee: Sun Xiaowei Document name: Notice of termination of patent right |
|
| DD01 | Delivery of document by public notice | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20151125 Termination date: 20200329 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |