CN103492588A - 用于单体型测定的方法和系统 - Google Patents

用于单体型测定的方法和系统 Download PDF

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Publication number
CN103492588A
CN103492588A CN201280010224.XA CN201280010224A CN103492588A CN 103492588 A CN103492588 A CN 103492588A CN 201280010224 A CN201280010224 A CN 201280010224A CN 103492588 A CN103492588 A CN 103492588A
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nucleic acid
alleles
interest
haplotype
sequences
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J-B.范
J.S.费希尔
F.凯珀
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Illumina Inc
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Illumina Inc
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/50—Detection characterised by immobilisation to a surface
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Microbiology (AREA)
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  • Molecular Biology (AREA)
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  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201280010224.XA 2011-02-25 2012-02-24 用于单体型测定的方法和系统 Pending CN103492588A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161446890P 2011-02-25 2011-02-25
US61/446,890 2011-02-25
US201161509960P 2011-07-20 2011-07-20
US61/509,960 2011-07-20
PCT/US2012/026623 WO2012116331A2 (en) 2011-02-25 2012-02-24 Methods and systems for haplotype determination

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CN103492588A true CN103492588A (zh) 2014-01-01

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US (1) US20140045706A1 (https=)
EP (1) EP2678449A4 (https=)
JP (1) JP2014507164A (https=)
CN (1) CN103492588A (https=)
AU (1) AU2012222108A1 (https=)
CA (1) CA2824431A1 (https=)
WO (1) WO2012116331A2 (https=)

Cited By (3)

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CN105046105A (zh) * 2015-07-09 2015-11-11 天津诺禾医学检验所有限公司 染色体跨度的单体型图及其构建方法
CN105385755A (zh) * 2015-11-05 2016-03-09 上海序康医疗科技有限公司 一种利用多重pcr技术进行snp-单体型分析的方法
CN112795563A (zh) * 2021-03-23 2021-05-14 上海欣百诺生物科技有限公司 生物素化的转座体在回收CUT&Tag或ATAC-seq产物中的用途及方法

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105046105A (zh) * 2015-07-09 2015-11-11 天津诺禾医学检验所有限公司 染色体跨度的单体型图及其构建方法
CN105046105B (zh) * 2015-07-09 2018-02-02 天津诺禾医学检验所有限公司 染色体跨度的单体型图及其构建方法
CN105385755A (zh) * 2015-11-05 2016-03-09 上海序康医疗科技有限公司 一种利用多重pcr技术进行snp-单体型分析的方法
CN112795563A (zh) * 2021-03-23 2021-05-14 上海欣百诺生物科技有限公司 生物素化的转座体在回收CUT&Tag或ATAC-seq产物中的用途及方法

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WO2012116331A2 (en) 2012-08-30
AU2012222108A1 (en) 2013-07-18
EP2678449A2 (en) 2014-01-01
JP2014507164A (ja) 2014-03-27
CA2824431A1 (en) 2012-08-30
EP2678449A4 (en) 2015-06-24
US20140045706A1 (en) 2014-02-13
WO2012116331A3 (en) 2013-03-07

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