CN103484233A - Method and device for preparing garlic oil with racemate alliin as raw materials - Google Patents
Method and device for preparing garlic oil with racemate alliin as raw materials Download PDFInfo
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- CN103484233A CN103484233A CN201310426154.2A CN201310426154A CN103484233A CN 103484233 A CN103484233 A CN 103484233A CN 201310426154 A CN201310426154 A CN 201310426154A CN 103484233 A CN103484233 A CN 103484233A
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Abstract
The invention discloses a method and device for preparing garlic oil with racemate alliin as raw materials. The method includes the following steps: (1) loading garlic, green onion, onion or allium chinensis into a reactor after the garlic, the green onion, the onion or the allium chinensis is washed, peeled and triturated, then adding an alliin solution, meanwhile, leading in air, and stirring and/or carrying out the reaction under the ultrasound condition, and (2) adding organic solvents into a reaction system after the reaction begins to carry out continuous extraction, obtaining extracted liquor, then adding edible fat and oil, water, ethyl alcohol or acetic acid into the extracted liquor, enabling the extracted liquor to be concentrated and separated in a vacuum mode at the temperature of 30-100DEG C, and obtaining the garlic oil. According to the method for preparing the garlic oil, the racemate alliin is added in the garlic, alliinase contained in the garlic is used for enabling the alliin to be converted into the garlic oil, the natural attribute of the garlic oil is kept, the yield of the garlic oil can be greatly improved, the method is simple and easy to achieve, and quite remarkable economic benefits are achieved.
Description
Technical field
The invention belongs to the bio-transformation field, be specifically related to a kind ofly take the raceme alliin and prepare method and the device thereof of Oleum Bulbus Allii as raw material.
Background technology
Oleum Bulbus Allii is the liquid mixture with important biomolecule activity, there is antibiotic, antiviral, anti-aging, anti-metal poisoning widely, cancer-resisting, the effect such as anti-oxidant, can be used for treating infectious diseases, digestive system, oral disease, cardiovascular and cerebrovascular diseases etc.Simultaneously, Oleum Bulbus Allii is also a kind of important fodder additives, can improve the surviving rate of food consumption, feed conversion rate and the animal of animal, reduces animal disease, and can improve animal product meat etc.Be not difficult to find out, Oleum Bulbus Allii is of many uses, and market demand is very huge.
At present, the source of Oleum Bulbus Allii and preparation mainly contain two kinds of modes: first kind of way is directly from garlic, to extract, and extracting method comprises supercritical methanol technology, steam method, solvent method, and because of the extracting method difference, there is significant difference in the yield of Oleum Bulbus Allii.The maximum characteristics of the method are that the product obtained is all-natural product, shortcoming is that in garlic, the content of amounting to of Oleum Bulbus Allii only has 0.3%, thereby being subject to the restriction, particularly recent years of garlic resource, skyrocket and make the production cost of Oleum Bulbus Allii climb up and up in garlic price one tunnel.The second way is chemical synthesis, the product that this method obtains and natural garlic main body of oil are basically identical, synthetic efficiency and yield are all very high, but because the chemical feedstocks used in chemical synthesis may be difficult to thoroughly except clean, so can cause unavoidably the worry of people to security, therefore at present synthetic Oleum Bulbus Allii mainly is used as the additive of feed.
Summary of the invention
For solving the shortcoming and defect part of prior art, primary and foremost purpose of the present invention is to provide a kind of and take the raceme alliin and prepare the method for Oleum Bulbus Allii as raw material, this preparation method be take the raceme alliin as raw material, under the condition of not separating the purifying allinase, join garlic after directly above-mentioned raw materials being made into to the aqueous solution, green onion, in an onion or Onion mud, then use the organic solvent continuous extraction, add water in extraction liquid, food oils, ethanol or acetic acid, induce garlicin to decompose, then reclaim solvent, obtain Oleum Bulbus Allii, simple, cost is low, productive rate is high, economic benefit with highly significant.
Another object of the present invention is to provide a kind of take the raceme alliin and prepares the device of Oleum Bulbus Allii as raw material.
For achieving the above object, the present invention adopts following technical scheme:
A kind ofly take the raceme alliin as raw material prepares the method for Oleum Bulbus Allii, comprise the following steps:
Step 1, by more than one in garlic, green onion, onion or Onion head, through cleaning, peeling and smash to pieces after pack in reactor, then add raceme alliin solution, flow velocity with 10～2000mL/min passes into air simultaneously, then under stirring and/or ultrasound condition, reacts;
Step 2, reaction started after 10～60 minutes, to the flow velocity with 50～1000mL/h in reaction system, added organic solvent, carried out continuous extraction in raw material reaction, was extracted liquid; Extraction liquid, in 30～100 ℃ of vacuum concentration, separation, is obtained to described Oleum Bulbus Allii.
Raceme alliin of the present invention (having another name called SACS) according to: build Liu Wenying; Three kinds of main alliins synthetic and characterizing in garlic, Chinese seasonings, 2011,36(9) 37-40, in synthetic the obtaining of method.
Preferably, the raceme alliin in the alliin of raceme described in step 1 solution, with the mass ratio of garlic, green onion, onion or Onion head be 5:1000～5:100.
Preferably, the concentration of the alliin of raceme described in step 1 solution is 0.0001～0.1mol/L.
Preferably, air flow quantity described in step 1 is 100～1000 (mL/min)/kg with the quality ratio of the garlic of throwing, green onion, onion or Onion head.
Preferably, described in step 1, garlic, green onion, onion or Onion head are cleaned, peeling and the service temperature of smashing process to pieces be 2～35 ℃; Stirring velocity described in step 1 is 100～1000r/min; Described ultrasonic frequency is 10～100kHz; Described temperature of reaction is 20～40 ℃.
Preferably, first add a kind of mixing in water, food oils, acetic acid or ethanol after being extracted liquid in step 2, then extraction liquid is carried out to vacuum concentration; 0～5 times of raceme alliin quality in the raceme alliin solution that the quality of described water, food oils, acetic acid or ethanol is step 1.
Preferred, 0.25～5 times of the raceme alliin quality in the raceme alliin solution that the amount of described water, food oils, acetic acid or ethanol is step 1.
Preferably, organic solvent described in step 2 comprises a kind of in sherwood oil, Skellysolve A, normal hexane, isohexane or ethyl acetate.
After organic solvent extraction in the present invention, recyclable after cooling.Room temperature of the present invention refers to 20～35 ℃.
Preferably, start to add the time of organic solvent in step 2, for reacting beginning after 10～30 minutes; The flow velocity of organic solvent is 50～600mL/h.
A kind ofly take the raceme alliin as raw material prepares the device of Oleum Bulbus Allii, comprise reaction system and vacuum concentration system; Described reaction system comprises the reactor with stirring rake, and described reactor head is connected with material feeding tube and solvent feed pipe, and reactor bottom is connected with air feed pipe, and reactor top is connected with the extraction phase discharge nozzle;
Described vacuum concentration system comprises extraction liquid storage tank, vaporizer, cyclonic separator, condenser, solvent tank, Oleum Bulbus Allii storage tank and valve tube; Extraction liquid storage tank, vaporizer and cyclonic separator are connected successively, and solvent tank all is connected with cyclonic separator with the Oleum Bulbus Allii storage tank; Described valve tube is connected with condenser;
Described vacuum concentration system, by solvent feed pipe and extraction phase discharge nozzle, is connected with reaction system; Extraction phase discharge nozzle two ends are ligation device and extraction liquid storage tank respectively, and solvent feed pipe two ends are ligation device and solvent tank respectively.
Preferably, described extraction liquid storage tank is provided with feed-pipe.
Low for alliin content in garlic, cause directly extracting the yield problem on the low side of Oleum Bulbus Allii from garlic, the present invention adopts to the raceme alliin that adds synthetic in garlic, that utilize in garlic that itself contains and without the allinase of separation and purification, alliin is changed into to Oleum Bulbus Allii.Described vacuum concentration system realizes vacuum concentration by valve tube.
Comparatively speaking the present invention and current technology, have the following advantages and beneficial effect:
1) to utilize the mechanism of garlicin different decomposition in different solvents (be the solvent effect in the present invention, as water, there are hydrogen bond action in acetic acid and garlicin, and only there are Van der Waals force in the organic solvent of food oils or extraction and garlicin) carry out the product regulation and control, by solvent effect and temperature level, change the decomposition approach of garlicin, obtain the Oleum Bulbus Allii of heterogeneity: need to have better nutritivity to be worth, and in the time of can tolerating relatively heavier foul smell, can select water or acetic acid to be added drop-wise in extraction liquid, then concentrated at 60～100 ℃ of temperature, can obtain mainly with diallyl disulphide, the product that Diallytrisin is main component (these two kinds of material total contents account for gross weight more than 55%), otherwise, very sensitive to stink, and when biological activity is not taken notice of very much (being mainly used in seasoning), can select food oils or ethanol to mix with extraction liquid, concentrate and can obtain 3-vinyl-1 at 30～60 ℃ of temperature, 2-bis-sulphur hexamethylenes-5-alkene and 3-vinyl-1,2-bis-product (total amount of these two kinds of materials accounts for gross weight more than 60%) that the sulphur hexamethylene-4-alkene is main component.
2) the present invention has overcome the problem of allinase easy inactivation in reaction, the work-ing life of significantly improving enzyme.From the alliin to the Oleum Bulbus Allii, pilot process has an important intermediate garlicin, garlicin is monomeric compound, this compound is very unstable, in the process of extracting, be very easy to resolve into a series of sulfocompound, and garlicin can react with sulfydryl in allinase, cause the too early inactivation of allinase.The present invention, by the method for limit coronite extraction, is conducive in time reaction product be shifted out to system, and garlicin is shifted out outside system, makes allinase have the longer life-span, prevents that product from causing the inactivation of enzyme, improves the work-ing life of enzyme, improves reaction efficiency.
3) cost advantage.The alliin of using in a, prior art is all the optical activity alliin, chemical name: (S)-3-(allyl group sulfinyl)-ALANINE, and theoretical specific rotation light value is+63.5; And the alliin raw material that the present invention uses is raceme, specific rotation is 0, the cost of raceme alliin greatly about 1/100～1/1000 left and right of natural alliin (in garlic, alliin is the optical activity alliin, content in garlic only 1%, and the leaching process complexity, so price is high).The present invention adopts the raceme alliin to make raw material, and raw materials cost significantly lowers; B, the present invention do not need allinase is carried out to separation and purification, utilize in garlic that itself contains and carry out catalyzed conversion without the allinase of separation and purification, alliin is changed into to Oleum Bulbus Allii, can save a large amount of production costs.
4) security is good.Oleum Bulbus Allii prepared with the raceme alliin of chemosynthesis by the present invention, it forms and the Oleum Bulbus Allii directly extracted from garlic, no matter composition is basically identical (take raceme alliin and optical activity alliin as raw material or directly from garlic, extracts Oleum Bulbus Allii, all to utilize allinase first alliin to be changed into to garlicin, the unstable decomposition of garlicin produces Oleum Bulbus Allii), there is higher security and nutritive property; And in prior art with the Oleum Bulbus Allii of chemosynthesis because chemical feedstocks may be difficult to thoroughly, except clean, to have food safety risk, thus at present its for feed.
The accompanying drawing explanation
Fig. 1 is that the present invention be take the raceme alliin and prepared the setting drawing of Oleum Bulbus Allii as raw material.
Embodiment
Below in conjunction with embodiment and accompanying drawing, the present invention is described in further detail, but embodiments of the present invention are not limited to this.
As shown in Figure 1, a kind ofly take the raceme alliin as raw material prepares the device of Oleum Bulbus Allii, comprise reaction system I and vacuum concentration system II; Described reaction system I comprises the reactor 7 with stirring rake 3, and described reactor 7 tops are connected with material feeding tube 1 and solvent feed pipe 6, and reactor bottom is connected with air feed pipe 2, and reactor 7 tops are connected with extraction phase discharge nozzle 8;
Described vacuum concentration system II comprises extraction liquid storage tank 9, vaporizer 12, cyclonic separator 14, condenser 10, solvent tank 11, Oleum Bulbus Allii storage tank 15 and valve tube 13; Extraction liquid storage tank 9, vaporizer 12 and cyclonic separator 14 are connected successively, extraction liquid in extraction liquid storage tank 9 is after vaporizer 12 vacuum concentration, enter cyclonic separator 14 separation and obtain organic solvent and Oleum Bulbus Allii, organic solvent enters solvent tank 11 after by condenser 10 condensations, and Oleum Bulbus Allii enters Oleum Bulbus Allii storage tank 15; Described valve tube 13 is connected with condenser 10, and described vacuum concentration system II realizes vacuum concentration by valve tube 13;
Described vacuum concentration system II, by solvent feed pipe 6 and extraction phase discharge nozzle 8, is connected with the reaction system I, and extraction phase discharge nozzle 8 two ends are ligation device 7 and extraction liquid storage tank 9 respectively, and solvent feed pipe 6 two ends are ligation device 7 and solvent tank 11 respectively.
Described extraction liquid storage tank 9 is provided with feed-pipe 16.
The present invention is a kind of take the raceme alliin and prepares the method for Oleum Bulbus Allii as raw material, clean, peeling and smash to pieces after garlic, green onion, an onion or Onion raw material, add reactor 7 with raceme alliin solution from material feeding tube 1, pass into air from air feed pipe 2, then under the stirring of stirring rake 3, start reaction simultaneously; Reaction starts, after 10～60 minutes, from solvent feed pipe 6, to add organic solvent to carry out continuous extraction, is extracted liquid 4 and reacting phase 5; Extraction liquid 4 enters extraction liquid storage tank 9 from extraction phase discharge nozzle 8, then enter vaporizer 12 and carry out vacuum concentration under 30～100 ℃, concentrated solution separates and obtains Oleum Bulbus Allii product and organic solvent by cyclonic separator 14, Oleum Bulbus Allii product introduction Oleum Bulbus Allii storage tank 15 is preserved, organic solvent reclaims by condenser 10 condensations, and the organic solvent after recovery enters solvent tank 11 recycles.
In the process extracted, reacting phase 5 keeps reaction, thereby has realized reaction and extracted carrying out simultaneously, enhances productivity and product purity.
Extraction liquid 4 can first drip water, food oils, acetic acid or ethanol by feed-pipe 16 and be allocated, and then enters vaporizer 12 vacuum concentration.
Comparative Examples:
Step 1, take 1 kilogram of garlic, peeling, cleans, after 30 ℃ are smashed to pieces, joins reactor, pumps into the alliin solution 1500mL of 0.06mol/L, passes into air (flow is 300mL/min) simultaneously, then starts Vltrasonic device, and frequency is 40kHz; 20 ℃ of temperature of reaction;
Step 2, reaction starts, after 30 minutes, in reaction system, to add the 1000mL ethyl acetate at room temperature to carry out continuous extraction; Extraction liquid, at 30 ℃ of lower vacuum concentration, after separation and recovery solvent, obtains described Oleum Bulbus Allii 4.3 grams.
The alliin transformation efficiency is 55%.Adopt gas chromatographic detection, Oleum Bulbus Allii consists of 3-vinyl-1,2-bis-sulphur hexamethylenes-5-alkene accounts for the relative percentage composition of 69.481%() and 3-vinyl-1,2-bis-sulphur hexamethylenes-4-alkene accounts for 11.043%, and diallyl disulphide and Diallytrisin and diallyl thioether do not detect substantially.
Embodiment 1:
Step 1, take 1 kilogram of garlic, peeling, cleans, after 30 ℃ are smashed to pieces, joins reactor, and pump into the alliin solution 1500mL of 0.06mol/L, passes into air (flow is 300mL/min) simultaneously, then starts Vltrasonic device, and frequency is 40kHz; 20 ℃ of temperature of reaction;
Step 2, reaction starts, after 20 minutes, to add the ethyl acetate that flow velocity is 100mL/h at room temperature to carry out continuous extraction, is extracted liquid and reacting phase; Extraction liquid is at 30 ℃ of lower vacuum concentration, and the concentrated solution separation obtains Oleum Bulbus Allii product 7.1 grams and organic solvent.The organic solvent recycle.
The alliin transformation efficiency is 85%.Adopt gas chromatographic detection, Oleum Bulbus Allii consists of 3-vinyl-1,2-bis-sulphur hexamethylenes-5-alkene accounts for the relative percentage composition of 70.40%() and 3-vinyl-1,2-bis-sulphur hexamethylenes-4-alkene accounts for 12.01%, and diallyl disulphide and Diallytrisin and diallyl thioether do not detect substantially.
Embodiment 2:
Step 1, take 1 kilogram of garlic, peeling, clean, join reactor 7 from material feeding tube 1 after 25 ℃ are smashed to pieces, and pump into the raceme alliin solution 2000mL of 0.01mol/L from material feeding tube 1, pass into air (flow is 200mL/min) from air feed pipe 2, then start stirring rake 3, rotating speed is 100r/min; 20 ℃ of temperature of reaction;
Step 2, reaction starts, after 10 minutes, from solvent feed pipe 6, to add the normal hexane that flow velocity is 50mL/h at room temperature to carry out continuous extraction, is extracted liquid 4 and reacting phase 5; Dripping 2mL water from feed-pipe 16 makes it simply mix (not exclusively mixing) with extraction liquid, extraction liquid 4 enters extraction liquid storage tank 9 from extraction phase discharge nozzle 8, then enter vaporizer 12 and at 100 ℃ of lower vacuum concentration, concentrated solution separates and obtains Oleum Bulbus Allii product 3.9 grams and organic solvent by cyclonic separator 14, Oleum Bulbus Allii product introduction Oleum Bulbus Allii storage tank 15 is preserved, organic solvent reclaims by condenser 10 condensations, organic solvent after recovery and separate a small amount of water after, enter solvent tank 11 recycles.
The alliin transformation efficiency is 93%.Adopt gas chromatographic detection, Oleum Bulbus Allii consists of 3-vinyl-1,2-bis-sulphur hexamethylenes-5-alkene accounts for the relative percentage composition of 20.88%() and 3-vinyl-1,2-bis-sulphur hexamethylenes-4-alkene accounts for 2.22%, diallyl disulphide accounts for 17.34%, and Diallytrisin accounts for 40.21%, and diallyl thioether accounts for 3.11%.
Embodiment 3:
Step 1, take 1 kilogram of garlic, peeling, cleans, after 2 ℃ are smashed to pieces, joins reactor, and pump into the raceme alliin solution 2000mL of 0.02mol/L, pass into air (flow is 500mL/min), then start the stirring rake stirring reaction, rotating speed is 500r/min; 30 ℃ of temperature of reaction;
Step 2, reaction starts, after 30 minutes, to add the Skellysolve A that flow velocity is 100mL/h at room temperature to carry out continuous extraction, is extracted liquid and reacting phase; Add 3mL acetic acid to mix with extraction liquid, then by extraction liquid at 60 ℃ of lower vacuum concentration, obtain Oleum Bulbus Allii product 5.6 grams and organic solvent after concentrated solution separates.Organic solvent is recycle after alkali cleaning.
The alliin transformation efficiency is 90%.Adopt gas chromatographic detection, Oleum Bulbus Allii consists of 3-vinyl-1,2-bis-sulphur hexamethylenes-5-alkene accounts for the relative percentage composition of 26.23%() and 3-vinyl-1,2-bis-sulphur hexamethylenes-4-alkene accounts for 3.22%, diallyl disulphide accounts for 18.34%, and Diallytrisin accounts for 37.22%, and diallyl thioether accounts for 2.01%.
Embodiment 4:
Step 1, take 1 kilogram of garlic, peeling, joins reactor after cleaning, smashing to pieces under 10 ℃, and pump into the raceme alliin solution 1000mL of 0.1mol/L, pass into air (flow is 1000mL/min), then start the stirring rake stirring reaction, rotating speed is 1000r/min; 40 ℃ of temperature of reaction;
Step 2, reaction starts, after 30 minutes, to add the isohexane that flow velocity is 100mL/h at room temperature to carry out continuous extraction, is extracted liquid and reacting phase; Add the 5mL food oils to mix with extraction liquid, then by extraction liquid at 50 ℃ of lower vacuum concentration, obtain Oleum Bulbus Allii product 6.5 grams and organic solvent after concentrated solution separates.The organic solvent recycle and reuse.
The alliin transformation efficiency is 65%.Adopt gas chromatographic detection, Oleum Bulbus Allii consists of 3-vinyl-1, and 2-bis-sulphur hexamethylenes-5-alkene accounts for the relative percentage composition of 14.45%() and 3-vinyl-1,2-bis-sulphur hexamethylenes-4-alkene accounts for 49.31%,, Diallytrisin accounts for 2.97%, and diallyl thioether and diallyl disulphide do not detect.
Embodiment 5:
Step 1, take 1 kilogram of Onion head, peeling, cleans, after 35 ℃ are smashed to pieces, joins reactor 7, and pump into the alliin solution 1400mL of 0.10mol/L, passes into air (flow is 500mL/min) simultaneously, then starts Vltrasonic device, and frequency is 100kHz; 40 ℃ of temperature of reaction;
Step 2, reaction starts, after 60 minutes, to add the sherwood oil that flow velocity is 1000mL/h at room temperature to carry out continuous extraction, is extracted liquid and reacting phase; Drip 10mL ethanol and mix with extraction liquid, then by extraction liquid at 40 ℃ of lower vacuum concentration, obtain Oleum Bulbus Allii product 5.2 grams and organic solvent after the concentrated solution separation.The organic solvent recycle and reuse.
The alliin transformation efficiency is 56%.Adopt gas chromatographic detection, Oleum Bulbus Allii consists of 3-vinyl-1, and 2-bis-sulphur hexamethylenes-5-alkene accounts for the relative percentage composition of 44.45%() and 3-vinyl-1,2-bis-sulphur hexamethylenes-4-alkene accounts for 28.31%,, Diallytrisin accounts for 5.77%, and diallyl thioether and diallyl disulphide do not detect.
Above-described embodiment is preferably embodiment of the present invention; but embodiments of the present invention are not restricted to the described embodiments; other any do not deviate from change, the modification done under spirit of the present invention and principle, substitutes, combination, simplify; all should be equivalent substitute mode, within being included in protection scope of the present invention.
Claims (10)
1. take the raceme alliin as raw material prepares the method for Oleum Bulbus Allii for one kind, it is characterized in that, comprise the following steps:
Step 1, by more than one in garlic, green onion, onion or Onion head, through cleaning, peeling and smash to pieces after pack in reactor, then add raceme alliin solution, flow velocity with 10～2000mL/min passes into air simultaneously, then under stirring and/or ultrasound condition, reacts;
Step 2, reaction started after 10～60 minutes, to the flow velocity with 50～1000mL/h in reaction system, added organic solvent, carried out continuous extraction in raw material reaction, was extracted liquid; Extraction liquid, in 30～100 ℃ of vacuum concentration, separation, is obtained to described Oleum Bulbus Allii.
2. preparation method according to claim 1, is characterized in that, the raceme alliin in the alliin of raceme described in step 1 solution, with the mass ratio of garlic, green onion, onion or Onion head be 1:100～5:100.
3. preparation method according to claim 1, is characterized in that, the concentration of the alliin of raceme described in step 1 solution is 0.0001～0.1mol/L.
4. preparation method according to claim 1, is characterized in that, air flow quantity described in step 1 is 100～1000 (mL/min)/kg with the quality ratio of the garlic of throwing, green onion, onion or Onion head.
5. preparation method according to claim 1, is characterized in that, described in step 1, by garlic, green onion, onion or Onion head, cleans, peeling and the service temperature of smashing process to pieces be 2～35 ℃; Stirring velocity described in step 1 is 100～1000r/min; Described ultrasonic frequency is 10～100kHz; Described temperature of reaction is 20～40 ℃.
6. preparation method according to claim 1, is characterized in that, organic solvent described in step 2 comprises a kind of in sherwood oil, Skellysolve A, normal hexane, isohexane or ethyl acetate.
7. preparation method according to claim 1, is characterized in that, first adds a kind of mixing in water, food oils, acetic acid or ethanol after being extracted liquid in step 2, then extraction liquid is carried out to vacuum concentration; 0～5 times of raceme alliin quality in the raceme alliin solution that the quality of described water, food oils, acetic acid or ethanol is step 1.
8. preparation method according to claim 1, is characterized in that, starts to add the time of organic solvent in step 2, for reacting beginning after 10～30 minutes; The flow velocity of organic solvent is 50～600mL/h.
9. take the raceme alliin as raw material prepares the device of Oleum Bulbus Allii for one kind, it is characterized in that, reaction unit comprises reaction system and vacuum concentration system; Described reaction system comprises the reactor with stirring rake, and described reactor head is connected with material feeding tube and solvent feed pipe, and reactor bottom is connected with air feed pipe, and reactor top is connected with the extraction phase discharge nozzle;
Described vacuum concentration system comprises extraction liquid storage tank, vaporizer, cyclonic separator, condenser, solvent tank, Oleum Bulbus Allii storage tank and valve tube; Extraction liquid storage tank, vaporizer and cyclonic separator are connected successively, and solvent tank all is connected with cyclonic separator with the Oleum Bulbus Allii storage tank; Described valve tube is connected with condenser;
Described vacuum concentration system, by solvent feed pipe and extraction phase discharge nozzle, is connected with reaction system; Extraction phase discharge nozzle two ends are ligation device and extraction liquid storage tank respectively, and solvent feed pipe two ends are ligation device and solvent tank respectively.
10. device according to claim 9, is characterized in that, described extraction liquid storage tank is provided with feed-pipe.
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Cited By (4)
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| CN104087627A (en) * | 2014-07-29 | 2014-10-08 | 江南大学 | Method for preparing gram-level high-purity natural thiosulfinate |
| CN108254460A (en) * | 2017-12-28 | 2018-07-06 | 云南农业大学 | A kind of method for detecting thio-ether type compounds in garlic root secretion |
| CN111796036A (en) * | 2020-07-07 | 2020-10-20 | 清远市食品检验中心 | Detection method for identifying natural garlic oil adulterated with synthetic garlic oil |
| CN114703239A (en) * | 2022-03-22 | 2022-07-05 | 辰欣药业股份有限公司 | Production method of allicin |
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| 祝晓凤: "蒜氨酸合成及相关分子印迹聚合物微球的制备", 《中国优秀硕士学位论文全文数据库 工程科技 I辑》 * |
| 黄雪松等: "利用新鲜大蒜生产结晶蒜氨酸", 《食品科学》 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104087627A (en) * | 2014-07-29 | 2014-10-08 | 江南大学 | Method for preparing gram-level high-purity natural thiosulfinate |
| CN108254460A (en) * | 2017-12-28 | 2018-07-06 | 云南农业大学 | A kind of method for detecting thio-ether type compounds in garlic root secretion |
| CN111796036A (en) * | 2020-07-07 | 2020-10-20 | 清远市食品检验中心 | Detection method for identifying natural garlic oil adulterated with synthetic garlic oil |
| CN114703239A (en) * | 2022-03-22 | 2022-07-05 | 辰欣药业股份有限公司 | Production method of allicin |
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