CN103479912B - A kind of Chinese medicinal ointment with wrinkle removal repair function - Google Patents

A kind of Chinese medicinal ointment with wrinkle removal repair function Download PDF

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Publication number
CN103479912B
CN103479912B CN201310412834.9A CN201310412834A CN103479912B CN 103479912 B CN103479912 B CN 103479912B CN 201310412834 A CN201310412834 A CN 201310412834A CN 103479912 B CN103479912 B CN 103479912B
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China
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extract
chinese medicinal
medicinal ointment
repair function
wrinkle removal
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Expired - Fee Related
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CN201310412834.9A
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Chinese (zh)
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CN103479912A (en
Inventor
吴红霞
武文婕
张钟文
韩梅
梁永娟
张军
张红
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Shandong Qianfoshan Hospital
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Shandong Qianfoshan Hospital
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Abstract

The invention discloses a kind of Chinese medicinal ointment with wrinkle removal repair function, composed of the following components: earth-worm extractive as raw material 0.5 ~ 1.5g, Cortex Moutan extract 0.5 ~ 1.5g, Herba portulacae extract 1.5 ~ 2.5g, Herba Lophatheri extract 0.5 ~ 1.5g, trehalose 4g, glycerol 5 ~ 10g, allantoin 1g, MEIGUI CHUNLU 200ml.The Chinese medicinal ointment with wrinkle removal repair function of the present invention, has and makes the skin obviously effect such as delicacy, elasticity obviously increases, wrinkle obviously shoals, moisture content of skin increase, can be used as moisturizing elite, be directly used in skin, to play the effect of crease-resistant reparation.The Chinese medicinal ointment with wrinkle removal repair function of the present invention, has the advantages such as activity is high, good biocompatibility, safety have no side effect.

Description

A kind of Chinese medicinal ointment with wrinkle removal repair function
Technical field
The present invention relates to a kind of Chinese medicinal ointment with wrinkle removal repair function.
Background technology
Skin aging is a kind of lasting gradual physiological process, direct cutaneous outward appearance and function.Wrinkle is then the one mark of skin aging performance, is referred to as " annual ring of life ".Along with the raising of people's quality of life, anti-aging, remove wrinkle, return to the topic that the youth become consumers in general to pay close attention to.
At present, along with the development of biochemical technology, people open the physiological mechanism of wrinkle just gradually, use biological active substances to improve skin and occur that the probability of wrinkle is increasing because of lax, centered by cosmetics producer, allow the research of the tip of perpetual youth on the face especially noticeable in recent years.Thus, anti-aging anti-wrinkle cosmetic is more and more valued by the people.
Skin aging is a part for body aging, and with age, skin there will be following outward manifestation: cutis laxa, thinning, and the water content of skin declines, and often seems dry, has squama, tarnish; Elasticity and consolidation also decline thereupon; Wrinkle is formed, and increases gradually, deepens.In addition, the sensitivity of skin increases, and pigment also increases.Hyperpigmentation is mainly seen in sun exposure position, as face, the back of the hand and forearm.Skin aging inherence shows as skin cell proliferation ability and declines, and epidermal renewal speed slows down, epidermal renewal reduced capability, and dermal collagen synthesis is slowed down, and skin immunization power declines, and Magnifying chromoscopy is unequal.
In prior art, for wrinkle formation basic theory and process, the anti-aging antiwrinkle active principle developed mainly comprises: the composition affecting tissue cell growth metabolism, as cell growth factor, some animals and plants extract, fruit acid, sheep placental extract etc.; Promote skin moisture-keeping and the active component repairing skin barrier function, as ceramide, hyaluronic acid, pyrrolidone sodium carboxylate etc.; The composition of anti-oxidative damage, as superoxide dismutase, glutathione peroxidase, vitamin E and vitamin C, coenzyme Q10 etc.
Summary of the invention
For above-mentioned prior art, the invention provides a kind of Chinese medicinal ointment with wrinkle removal repair function of better effects if.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicinal ointment with wrinkle removal repair function, composed of the following components: earth-worm extractive as raw material 0.5 ~ 1.5g, Cortex Moutan extract 0.5 ~ 1.5g, Herba portulacae extract 1.5 ~ 2.5g, Herba Lophatheri extract 0.5 ~ 1.5g, trehalose 4g, glycerol 5 ~ 10g, allantoin 1g, MEIGUI CHUNLU 200ml.
Preferably, be composed of the following components: earth-worm extractive as raw material 1g, Cortex Moutan extract 1g, Herba portulacae extract 2g, Herba Lophatheri extract 1g, trehalose 4g, glycerol 8g, allantoin 1g, MEIGUI CHUNLU 200ml.
Described earth-worm extractive as raw material obtains by the following method: get Lumbricus 100g, adds 800 ~ 1200ml, 60 ~ 80%(volume fraction) ethanol, extract 3 ~ 8h, filter to get filtrate, filtrate reduced in volume, lyophilization obtain powder, to obtain final product.
Described Cortex Moutan extract obtains by the following method: get Cortex Moutan 100g, adds 800 ~ 1200ml, 80 ~ 95%(volume fraction) ethanol, extract 3 ~ 5h, filter to get filtrate, filtrate reduced in volume, lyophilization obtain powder, to obtain final product.
Described Herba portulacae extract obtains by the following method: get Herba Portulacae 100g, adds 800 ~ 1200ml water, decocts 2 ~ 4h, filters to obtain decocting liquid, and decocting liquid is concentrated, dry obtains powder, to obtain final product.
Described Herba Lophatheri extract obtains by the following method: get Herba Lophatheri 100g, adds 800 ~ 1200ml water, decocts 2 ~ 4h, filters to obtain decocting liquid, and decocting liquid is concentrated, dry obtains powder, to obtain final product.
The described preparation method with the Chinese medicinal ointment of wrinkle removal repair function, for: get each component, mixing mixing, to obtain final product.
Described MEIGUI CHUNLU is existing conventional products in prior art, does not repeat them here.
The Chinese medicinal ointment with wrinkle removal repair function of the present invention, has and makes the skin obviously effect such as delicacy, elasticity obviously increases, wrinkle obviously shoals, moisture content of skin increase, can be used as moisturizing elite, be directly used in skin, to play the effect of crease-resistant reparation.The Chinese medicinal ointment with wrinkle removal repair function of the present invention, has the advantages such as activity is high, good biocompatibility, safety have no side effect.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment 1: preparation has the Chinese medicinal ointment of wrinkle removal repair function
Formula is: earth-worm extractive as raw material 1g, Cortex Moutan extract 1g, Herba portulacae extract 2g, Herba Lophatheri extract 1g, trehalose 4g, glycerol 8g, allantoin 1g, MEIGUI CHUNLU 200ml.
Preparation method is: get each component, and mixing mixing, to obtain final product.
Described earth-worm extractive as raw material obtains by the following method: get Lumbricus 100g, adds 1000ml 70%(volume fraction) ethanol, extract 5h, filter to get filtrate, filtrate reduced in volume, lyophilization obtain powder, to obtain final product.
Described Cortex Moutan extract obtains by the following method: get Cortex Moutan 100g, adds 1000ml 90%(volume fraction) ethanol, extract 4h, filter to get filtrate, filtrate reduced in volume, lyophilization obtain powder, to obtain final product.
Described Herba portulacae extract obtains by the following method: get Herba Portulacae 100g, adds 1000ml water, decocts 3h, filters to obtain decocting liquid, and decocting liquid is concentrated, dry obtains powder, to obtain final product.
Described Herba Lophatheri extract obtains by the following method: get Herba Lophatheri 100g, adds 1000ml water, decocts 3h, filters to obtain decocting liquid, and decocting liquid is concentrated, dry obtains powder, to obtain final product.
Embodiment 2: preparation has the Chinese medicinal ointment of wrinkle removal repair function
Formula is: earth-worm extractive as raw material 0.5g, Cortex Moutan extract 1.5g, Herba portulacae extract 1.5g, Herba Lophatheri extract 1.5g, trehalose 4g, glycerol 5g, allantoin 1g, MEIGUI CHUNLU 200ml.
Preparation method is: get each component, and mixing mixing, to obtain final product.
Described earth-worm extractive as raw material obtains by the following method: get Lumbricus 100g, adds 800ml 80%(volume fraction) ethanol, extract 3h, filter to get filtrate, filtrate reduced in volume, lyophilization obtain powder, to obtain final product.
Described Cortex Moutan extract obtains by the following method: get Cortex Moutan 100g, adds 800ml 95%(volume fraction) ethanol, extract 5h, filter to get filtrate, filtrate reduced in volume, lyophilization obtain powder, to obtain final product.
Described Herba portulacae extract obtains by the following method: get Herba Portulacae 100g, adds 1200ml water, decocts 4h, filters to obtain decocting liquid, and decocting liquid is concentrated, dry obtains powder, to obtain final product.
Described Herba Lophatheri extract obtains by the following method: get Herba Lophatheri 100g, adds 1200ml water, decocts 4h, filters to obtain decocting liquid, and decocting liquid is concentrated, dry obtains powder, to obtain final product.
Embodiment 3: preparation has the Chinese medicinal ointment of wrinkle removal repair function
Formula is: earth-worm extractive as raw material 1.5g, Cortex Moutan extract 0.5g, Herba portulacae extract 2.5g, Herba Lophatheri extract 0.5g, trehalose 4g, glycerol 10g, allantoin 1g, MEIGUI CHUNLU 200ml.
Preparation method is: get each component, and mixing mixing, to obtain final product.
Described earth-worm extractive as raw material obtains by the following method: get Lumbricus 100g, adds 1200ml 60%(volume fraction) ethanol, extract 8h, filter to get filtrate, filtrate reduced in volume, lyophilization obtain powder, to obtain final product.
Described Cortex Moutan extract obtains by the following method: get Cortex Moutan 100g, adds 1200ml 80%(volume fraction) ethanol, extract 3h, filter to get filtrate, filtrate reduced in volume, lyophilization obtain powder, to obtain final product.
Described Herba portulacae extract obtains by the following method: get Herba Portulacae 100g, adds 800ml water, decocts 2h, filters to obtain decocting liquid, and decocting liquid is concentrated, dry obtains powder, to obtain final product.
Described Herba Lophatheri extract obtains by the following method: get Herba Lophatheri 100g, adds 800ml water, decocts 2h, filters to obtain decocting liquid, and decocting liquid is concentrated, dry obtains powder, to obtain final product.
Embodiment 4: the use sense evaluation in embodiment 1 with the Chinese medicinal ointment of wrinkle removal repair function
For the Chinese medicinal ointment with wrinkle removal repair function of preparation in embodiment 1,1ml Chinese medicinal ointment is spread evenly across 120 volunteers (28 years old to 45 years old volunteer's age, wherein male volunteer 40, female volunteer 80 at every turn; Face has microgroove, and some position wrinkle is obvious) face, with do not add earth-worm extractive as raw material and, the Chinese medicinal ointment (consumption of all the other components is with embodiment 1) of Cortex Moutan extract, Herba portulacae extract and Herba Lophatheri extract contrasts, and uses 30 days continuously.30 days its use senses of post-evaluation, skin texture situations.
Evaluation criterion: use sense is experienced by volunteer's readme; Skin texture situation, by naked eyes direct vision and skin texture experiment, wherein, is effectively: skin texture obviously attenuate greasy, perusal face microgroove obviously reduces, dark stricture of vagina shoals; Be generally: skin texture slightly shoals, perusal reduces than wrinkle before experiment, but reduces not obvious; Invalid: not to be any change before skin texture and experiment.
The results are shown in Table 1:
Table 1 has the Chinese medicinal ointment of wrinkle removal repair function table on probation
As seen from the above table, after wrinkle removal reparation astringent uses 30 days, most people's use sense is good, has obvious wrinkle removal repairing effect, especially remarkably productive with wrinkle removal.

Claims (3)

1. one kind has the Chinese medicinal ointment of wrinkle removal repair function, it is characterized in that: be composed of the following components: earth-worm extractive as raw material 0.5 ~ 1.5g, Cortex Moutan extract 0.5 ~ 1.5g, Herba portulacae extract 1.5 ~ 2.5g, Herba Lophatheri extract 0.5 ~ 1.5g, trehalose 4g, glycerol 5 ~ 10g, allantoin 1g, MEIGUI CHUNLU 200ml;
Described earth-worm extractive as raw material obtains by the following method: get Lumbricus 100g, adds the ethanol of 800 ~ 1200ml 60 ~ 80%, and extract 3 ~ 8h, filter to get filtrate, filtrate reduced in volume, lyophilization obtain powder, to obtain final product;
Described Cortex Moutan extract obtains by the following method: get Cortex Moutan 100g, adds the ethanol of 800 ~ 1200ml 80 ~ 95%, and extract 3 ~ 5h, filter to get filtrate, filtrate reduced in volume, lyophilization obtain powder, to obtain final product;
Described Herba portulacae extract obtains by the following method: get Herba Portulacae 100g, adds 800 ~ 1200ml water, decocts 2 ~ 4h, filters to obtain decocting liquid, and decocting liquid is concentrated, dry obtains powder, to obtain final product;
Described Herba Lophatheri extract obtains by the following method: get Herba Lophatheri 100g, adds 800 ~ 1200ml water, decocts 2 ~ 4h, filters to obtain decocting liquid, and decocting liquid is concentrated, dry obtains powder, to obtain final product.
2. the Chinese medicinal ointment with wrinkle removal repair function according to claim 1, is characterized in that: be composed of the following components: earth-worm extractive as raw material 1g, Cortex Moutan extract 1g, Herba portulacae extract 2g, Herba Lophatheri extract 1g, trehalose 4g, glycerol 8g, allantoin 1g, MEIGUI CHUNLU 200ml.
3. the preparation method with the Chinese medicinal ointment of wrinkle removal repair function described in claim 1 or 2, is characterized in that: get each component, and mixing mixing, to obtain final product.
CN201310412834.9A 2013-09-12 2013-09-12 A kind of Chinese medicinal ointment with wrinkle removal repair function Expired - Fee Related CN103479912B (en)

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EP3721944A1 (en) * 2013-09-22 2020-10-14 Cutech S.R.L. Extracts of halimione portulacoides and their application
CN105326691B (en) * 2015-11-11 2018-05-08 广州暨南生物医药研究开发基地有限公司 A kind of spray of the hydrosol containing wormwood and preparation method thereof
CN106344484A (en) * 2016-09-13 2017-01-25 广西顺帆投资有限公司 Whitening and freckle removing sleeping mask and method for preparing same

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CN1485024A (en) * 2002-09-28 2004-03-31 戚海波 Bee honey and its use in beautifying cosmetics
CN100546562C (en) * 2007-08-24 2009-10-07 杨凌无为制药有限公司 A kind of Chinese medicine essence cream for dispelling speckle and whitening
CN101444475B (en) * 2008-12-26 2010-12-22 北京工商大学 Traditional Chinese medicine extract with all-purpose free radical removal efficacy and preparation method thereof
CN101444474A (en) * 2008-12-26 2009-06-03 北京工商大学 Rhodiola root extract with senile-resistant efficacy and preparation method thereof
CN101953762A (en) * 2009-07-16 2011-01-26 王庆才 Rose wrinkle resistant skin lotion and preparation method thereof
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Inventor after: Wu Hongxia

Inventor after: Wu Wenjie

Inventor after: Zhang Zhongwen

Inventor after: Han Mei

Inventor after: Liang Yongjuan

Inventor after: Zhang Jun

Inventor after: Zhang Hong

Inventor before: Wu Hongxia

Inventor before: Hou Jun

Inventor before: Zhang Zhongwen

Inventor before: Han Mei

Inventor before: Liang Yongjuan

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Free format text: CORRECT: INVENTOR; FROM: WU HONGXIA HOU JUN ZHANG ZHONGWEN HAN MEI LIANG YONGJUAN TO: WU HONGXIA WU WENJIE ZHANG ZHONGWEN HAN MEI LIANG YONGJUAN ZHANG JUN ZHANG HONG

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