CN103479883B - Tissue regeneration promoting ulcer recovering oil used for treating diabetic foot ulcer - Google Patents
Tissue regeneration promoting ulcer recovering oil used for treating diabetic foot ulcer Download PDFInfo
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- CN103479883B CN103479883B CN201310427078.7A CN201310427078A CN103479883B CN 103479883 B CN103479883 B CN 103479883B CN 201310427078 A CN201310427078 A CN 201310427078A CN 103479883 B CN103479883 B CN 103479883B
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Abstract
The invention discloses tissue regeneration promoting ulcer recovering oil used for treating the diabetic foot ulcer. Dragon's blood, bletilla striata, frankincense, myrrh and catechu are used for invigorating blood circulation, removing blood stasis and promoting tissue regeneration and serve as monarch drugs. Chinese angelica, ligusticum wallichii, red paeony roots, savia miltiorrhiza, red flowers and caulis spatholobi are used for promoting blood circulation to remove meridian obstruction and serve as ministerial drugs. Ligusticum wallichii, rihizoma corydalis, borneol and radix aconite are used for promoting blood circulation to arrest pain and are in coordination with the monarch drugs and the ministerial drugs to strength the treatment effect. Lithospermum, cortex moutan, folium isatidis and dandelion are used for removing heat to cool blood, resolving toxin and dispersing swelling. Menthe haplocalyx and borneol are transdermal to be used for removing cool. Radix angelicae, golden cypress and radix sophorae flavescentis are used for clearing heat, drying dampness, dispersing swelling and discharging pus. Various components are reasonably prepared to jointly have the effects of promoting blood circulation to remove blood stasis, dispersing swelling to pomote tissue regeration and clearing heat and toxic materials to discharge pus are jointly achieved, therefore, stasis is removed, meridian obstruction is removed, acra vital energy and blood flow freely, muscle nutrition is sufficient, the ulcer is removed, the tissue is generated, and the foot ulcer caused by the diabetes is effectively cured. The tissue regeneration promoting ulcer recovering oil is high in cure rate and low in treatment cost.
Description
Technical field
the present invention relates to tcm field, be specifically related to a kind of granulation promoting being used for the treatment of diabetic foot ulcer and heal infections oil.
Background technology
Diabetes are one group take hyperglycemia as the metabolic disease of feature caused by defect of insulin secretion and/or insulin action obstacle.Persistent high blood sugar and long-term metabolic are disorderly etc. can cause the infringement of body tissue's organ and dysfunction thereof and exhaustion.Current maturity-onset diabetes patient populations is estimated to exceed 100,000,000, and China has become diabetes populous nation, forms challenge Chinese society and public health.Diabetic foot ulcer is one of complication of diabetes, the diabetes patient at main finger initial stage, there is not the crowd of peripheral neuropathy and peripheral angiopathy, but occurred foot infection as paronychia, beriberi infection etc. cause foot infection, suppurate, the symptom such as to fester.Can there is ulcer of foot at it in the diabetes patient of about 15%, be difficult to control in life during infection, and amputation rate is high, has a strong impact on the quality of life of diabetes patient, and diabetes patient's amputation of more than 80% results from ulcer of foot according to statistics.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of granulation promoting being used for the treatment of diabetic foot ulcer and heals infections oil, and pure Chinese drug preparation, ulcer surface external application, evident in efficacy, no pain, cure rate is high, and treatment cost is low.
The present invention is achieved through the following technical solutions:
A kind of granulation promoting being used for the treatment of diabetic foot ulcer heals infections oil, be dipped into jaundice Jiao by the component of following weight portion through 300 DEG C ~ 500 DEG C high temperature oil to make, Radix Angelicae Sinensis 15 ~ 25 parts, Rhizoma Chuanxiong 15 ~ 25 parts, Radix Paeoniae Rubra 15 ~ 25 parts, 15 ~ 25 parts, Flos Carthami, Caulis Spatholobi 15 ~ 25 parts, Radix Salviae Miltiorrhizae 15 ~ 25 parts, Caulis Sargentodoxae 15 ~ 25 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 ~ 25 parts, Olibanum 15 ~ 25 parts, Myrrha 15 ~ 25 parts, Sanguis Draxonis 15 ~ 25 parts, 15 ~ 25 parts, catechu, Cortex Moutan 25 ~ 35 parts, Radix Aconiti 10 ~ 20 parts, Rhizoma Corydalis 25 ~ 35 parts, Radix Arnebiae (Radix Lithospermi) 50 ~ 70 parts, Borneolum Syntheticum 10 ~ 20 parts, the Radix Angelicae Dahuricae 25 ~ 35 parts, Cortex Phellodendri 15 ~ 25 parts, Radix Sophorae Flavescentis 15 ~ 25 parts, Herba Menthae 15 ~ 25 parts, Herba Taraxaci 15 ~ 25 parts, Folium Isatidis 15 ~ 25 parts, 2000 ~ 4000 parts, Oleum Sesami.
The further improvement project of the present invention is, described Radix Angelicae Sinensis 20 parts, Rhizoma Chuanxiong 20 parts, Radix Paeoniae Rubra 20 parts, 20 parts, Flos Carthami, Caulis Spatholobi 20 parts, Radix Salviae Miltiorrhizae 20 parts, Caulis Sargentodoxae 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20 parts, Olibanum 20 parts, Myrrha 20 parts, Sanguis Draxonis 20 parts, 20 parts, catechu, Cortex Moutan 30 parts, Radix Aconiti 15 parts, Rhizoma Corydalis 30 parts, Radix Arnebiae (Radix Lithospermi) 60 parts, Borneolum Syntheticum 15 parts, the Radix Angelicae Dahuricae 30 parts, Cortex Phellodendri 20 parts, Radix Sophorae Flavescentis 20 parts, Herba Menthae 20 parts, Herba Taraxaci 20 parts, Folium Isatidis 20 parts, 3000 parts, Oleum Sesami.
Instant component is with Sanguis Draxonis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Olibanum, Myrrha, catechu blood circulation promoting and blood stasis dispelling granulation promoting is monarch drug, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Flos Carthami, Caulis Spatholobi promoting blood circulation to remove obstruction in the collateral is ministerial drug, Rhizoma Chuanxiong, Rhizoma Corydalis, Borneolum Syntheticum, Radix Aconiti promoting blood circulation and stopping pain, monarch-minister drug is coordinated to strengthen therapeutical effect, Radix Arnebiae (Radix Lithospermi), Cortex Moutan, Folium Isatidis, Herba Taraxaci clearing away heat,cooling blood and removing toxin is subsided a swelling, Herba Menthae, Borneolum Syntheticum transdermal is refrigerant, the Radix Angelicae Dahuricae, Cortex Phellodendri, Radix Sophorae Flavescentis heat clearing and damp drying, detumescence and apocenosis, each component reasonable preparation, play blood circulation promoting and blood stasis dispelling altogether, detumescence and promoting granulation, the merit of heat-clearing and toxic substances removing evacuation of pus, thus make stagnation resolvation ruton, acra normal circulation of qi and blood, muscle nutrition is sufficient, the skin ulcer meat that disappears is long, the ulcer of foot that effective healing diabetes cause.
Using method of the present invention: ulcer of foot wound surface povidone iodine cleans, remove slough and purulent secretion, each granulation promoting heal infections oil immersion bubble oil gauze external application wound surface, have chamber person can with granulation promoting heal infections oil gauze filling, then wrap up with sterile gauze, do not make foot pressurized, lifting affected limb, within 1 day, change dressings 1 time.
Beneficial effect of the present invention:
The present invention adopts pure Chinese drug preparation, for the external application of diabetic foot ulcer, evident in efficacy, no pain, and cure rate is high, and treatment cost is low.
Detailed description of the invention
Embodiment 1
Get Radix Angelicae Sinensis 20g, Rhizoma Chuanxiong 20g, Radix Paeoniae Rubra 20g, Flos Carthami 20g, Caulis Spatholobi 20g, Radix Salviae Miltiorrhizae 20g, Caulis Sargentodoxae 20g, Pseudobulbus Bletillae (Rhizoma Bletillae) 20g, Olibanum 20g, Myrrha 20g, Sanguis Draxonis 20g, catechu 20g, Cortex Moutan 30g, Radix Aconiti 15g, Rhizoma Corydalis 30g, Radix Arnebiae (Radix Lithospermi) 60g, Borneolum Syntheticum 15g, Radix Angelicae Dahuricae 30g, Cortex Phellodendri 20g, Radix Sophorae Flavescentis 20g, Herba Menthae 20g, Herba Taraxaci 20g, Folium Isatidis 20g, immerse in 3000g Oleum Sesami, temperature control 400 DEG C, oil immersion is sent out burnt to jaundice, and obtained granulation promoting heals infections oil.
Clinical treatment: ulcer of foot wound surface povidone iodine cleans, remove slough and purulent secretion, each granulation promoting heal infections oil immersion bubble oil gauze external application wound surface, have chamber person can with granulation promoting heal infections oil gauze filling, then with sterile gauze wrapping, lifting affected limb, does not make foot pressurized, within 1 day, changing dressings 1 time, 14 days is a course for the treatment of.
Bao, man, 45 years old, fasting glucose 7.9 mmol/L, early 2 hours blood glucose 11.2 mmol/L, glycolated hemoglobin 8.5 mg/dl after the meal, left sufficient diabetic foot ulcer one-level, ulcer area 121.4 mm
2, suppurating sore, cleans wound surface with povidone iodine, removes slough and purulent secretion, with the oil gauze external application wound surface that the present invention soaks, then with sterile gauze wrapping, lifting affected limb, does not make foot pressurized, within 1 day, change dressings 1 time, continuous smelting is treated 5 days local symptoms and is disappeared, and ulcer surface heals completely.
Week certain, female, 66 years old, fasting glucose 15.6 mmol/L, early 2 hours blood glucose 21.4mmol/L, glycolated hemoglobin 11.6 mg/dl after the meal, diabetic foot ulcer secondary, red swelling of the skin, festered, ulcer area 139.4 mm
2, clean wound surface with povidone iodine, remove slough and purulent secretion, the oil gauze external application wound surface soaked with the present invention, then with sterile gauze wrapping, lifting affected limb, does not make foot pressurized, within 1 day, change dressings 1 time, continuous smelting is treated 12 days local symptoms and is disappeared, and ulcer surface heals completely.
Hu, man, 72 years old, fasting glucose 14.5 mmol/L, early 2 hours blood glucose 19.5mmol/L, glycolated hemoglobin 11.5 mg/dl after the meal, diabetic foot ulcer three grades, red swelling of the skin, festered, and deep ulcer, forms ulcer chamber, ulcer area 145.5 mm
2, clean wound surface with povidone iodine, remove slough and purulent secretion, clog in intracavity and external application wound surface with the oil gauze that the present invention soaks, then with sterile gauze wrapping, lifting affected limb, does not make foot pressurized, within 1 day, change dressings 1 time, 14 days courses for the treatment of are treated in continuous smelting, and ulcer area reduces to 65.2 mm
2, continued treatment to 25 day, muscle groups tissue layer, fat deposit, skin corium, epidermal area recover original organizational structure, and complete smelting more.
Criterion of therapeutical effect: cure: local symptom disappears, and wound surface heals completely; Effective: local symptom obviously alleviates, wound surface more than 2/3 heals; Effective: local symptom alleviates, wound surface more than 1/2 heals; Invalid: local symptom and the equal inefficacy of wound surface.
With 14 days courses for the treatment of, clinical treatment 40 case, wherein: diabetic foot ulcer one-level 12 people, 5 ~ 6 days continuous treatment times, after treatment, 12 examples all transfer diabetic foot ulcer 0 grade to; Urine foot disease ulcer secondary 15 people, 6 ~ 14 days continuous treatment times, after treatment, 13 examples transfer diabetic foot ulcer 0 grade to, and 2 examples transfer diabetic foot ulcer 1 grade to; Diabetic foot ulcer secondary 15 people, 6 ~ 14 days continuous treatment times, after treatment, 13 examples transfer diabetic foot ulcer 0 grade to, and 2 examples transfer diabetic foot ulcer 1 grade to.Comprehensive therapeutic effect standard: 40 cases, cures 30 examples, effective 8, effective 2 examples, invalid 0 example, cure rate 75%.
Embodiment 2
Get Radix Angelicae Sinensis 15g, Rhizoma Chuanxiong 15g, Radix Paeoniae Rubra 15g, Flos Carthami 15g, Caulis Spatholobi 15g, Radix Salviae Miltiorrhizae 15g, Caulis Sargentodoxae 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Olibanum 15g, Myrrha 15g, Sanguis Draxonis 15g, catechu 15g, Cortex Moutan 30g, Radix Aconiti 15g, Rhizoma Corydalis 25g, Radix Arnebiae (Radix Lithospermi) 50g, Borneolum Syntheticum 10g, Radix Angelicae Dahuricae 25g, Cortex Phellodendri 15g, Radix Sophorae Flavescentis 15g, Herba Menthae 15g, Herba Taraxaci 15g, Folium Isatidis 15g, immerse in 2000g Oleum Sesami, temperature control 300 DEG C, oil immersion is sent out burnt to jaundice, and obtained granulation promoting heals infections oil.
Embodiment 3
Get Radix Angelicae Sinensis 25g, Rhizoma Chuanxiong 25g, Radix Paeoniae Rubra 25g, Flos Carthami 25g, Caulis Spatholobi 25g, Radix Salviae Miltiorrhizae 25g, Caulis Sargentodoxae 25g, Pseudobulbus Bletillae (Rhizoma Bletillae) 25g, Olibanum 25g, Myrrha 25g, Sanguis Draxonis 25g, catechu 25g, Cortex Moutan 35g, Radix Aconiti 20g, Rhizoma Corydalis 35g, Radix Arnebiae (Radix Lithospermi) 70g, Borneolum Syntheticum 20g, Radix Angelicae Dahuricae 35g, Cortex Phellodendri 25g, Radix Sophorae Flavescentis 25g, Herba Menthae 25g, Herba Taraxaci 25g, Folium Isatidis 25g, immerse in 4000g Oleum Sesami, temperature control 500 DEG C, oil immersion is sent out burnt to jaundice, and obtained granulation promoting heals infections oil.
Claims (2)
1. the granulation promoting being used for the treatment of diabetic foot ulcer heals infections oil, it is characterized in that: be dipped into jaundice Jiao by the component of following weight portion through 300 DEG C ~ 500 DEG C high temperature oil and make, Radix Angelicae Sinensis 15 ~ 25 parts, Rhizoma Chuanxiong 15 ~ 25 parts, Radix Paeoniae Rubra 15 ~ 25 parts, 15 ~ 25 parts, Flos Carthami, Caulis Spatholobi 15 ~ 25 parts, Radix Salviae Miltiorrhizae 15 ~ 25 parts, Caulis Sargentodoxae 15 ~ 25 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 ~ 25 parts, Olibanum 15 ~ 25 parts, Myrrha 15 ~ 25 parts, Sanguis Draxonis 15 ~ 25 parts, 15 ~ 25 parts, catechu, Cortex Moutan 25 ~ 35 parts, Radix Aconiti 10 ~ 20 parts, Rhizoma Corydalis 25 ~ 35 parts, Radix Arnebiae (Radix Lithospermi) 50 ~ 70 parts, Borneolum Syntheticum 10 ~ 20 parts, the Radix Angelicae Dahuricae 25 ~ 35 parts, Cortex Phellodendri 15 ~ 25 parts, Radix Sophorae Flavescentis 15 ~ 25 parts, Herba Menthae 15 ~ 25 parts, Herba Taraxaci 15 ~ 25 parts, Folium Isatidis 15 ~ 25 parts, 2000 ~ 4000 parts, Oleum Sesami.
2. the granulation promoting being used for the treatment of diabetic foot ulcer according to claim 1 heals infections oil, it is characterized in that: described Radix Angelicae Sinensis 20 parts, Rhizoma Chuanxiong 20 parts, Radix Paeoniae Rubra 20 parts, 20 parts, Flos Carthami, Caulis Spatholobi 20 parts, Radix Salviae Miltiorrhizae 20 parts, Caulis Sargentodoxae 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20 parts, Olibanum 20 parts, Myrrha 20 parts, Sanguis Draxonis 20 parts, 20 parts, catechu, Cortex Moutan 30 parts, Radix Aconiti 15 parts, Rhizoma Corydalis 30 parts, Radix Arnebiae (Radix Lithospermi) 60 parts, Borneolum Syntheticum 15 parts, the Radix Angelicae Dahuricae 30 parts, Cortex Phellodendri 20 parts, Radix Sophorae Flavescentis 20 parts, Herba Menthae 20 parts, Herba Taraxaci 20 parts, Folium Isatidis 20 parts, 3000 parts, Oleum Sesami.
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Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103784748B (en) * | 2014-03-11 | 2017-04-12 | 杨洪英 | Medicine for treating diabetic foot disease and preparing method thereof |
| CN104127804A (en) * | 2014-06-30 | 2014-11-05 | 华洪萍 | Traditional Chinese medicine capable of treating diabetic foot ulcer |
| CN104645230A (en) * | 2015-02-04 | 2015-05-27 | 郭敏 | Traditional Chinese medicine for assisting in treating diabetic foot and preparation method of foot soaking solution |
| CN104857200A (en) * | 2015-06-19 | 2015-08-26 | 济南邦文医药科技有限公司 | Traditional Chinese medicine for treating yin-damage by heat toxin type diabetic foot ulcer |
| CN105963474A (en) * | 2016-04-29 | 2016-09-28 | 于秀辰 | Traditional Chinese medicinal composition for treating diabetic foot ulcer, positive ulcer and positive sore and preparation method of traditional Chinese medicinal composition |
| CN106310143A (en) * | 2016-11-14 | 2017-01-11 | 河南中医药大学 | Foot bath drug for treating diabetic foot |
| CN110787281A (en) * | 2019-10-25 | 2020-02-14 | 运鸿集团股份有限公司 | Antibacterial peptide compound botanical drug gel for treating skin tissue ulcer infection and preparation method thereof |
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