CN103478820A - Eucommia male flower beverage - Google Patents

Eucommia male flower beverage Download PDF

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Publication number
CN103478820A
CN103478820A CN201310468954.0A CN201310468954A CN103478820A CN 103478820 A CN103478820 A CN 103478820A CN 201310468954 A CN201310468954 A CN 201310468954A CN 103478820 A CN103478820 A CN 103478820A
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male flower
eucommia bark
bark male
mulberry leaf
hawthorn
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郝玉东
高瑞文
陈之东
韦科
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SHANDONG BEILONG DUZHONG BIOLOGICAL ENGINEERING Co Ltd
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SHANDONG BEILONG DUZHONG BIOLOGICAL ENGINEERING Co Ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/60—Sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

An eucommia male flower beverage comprises the following raw materials by weight: 4-6 parts of eucommia male flower, 6-8 parts of honeysuckle, 6-8 parts of mulberry leaves and 3-5 parts of hawthorn; the eucommia flower drink is added with 0.3-0.4 part of stevioside, so as to prepare a sugar-free eucommia male flower beverage, or the eucommia flower drink is added with white granulated sugar accounting for 5-7 wt% of the total weight of eucommia male, honeysuckle, mulberry leaf and hawthorn, so as to obtain sugar-containing eucommia male flower beverage. Combination of the four components in the eucommia male flower beverage provided by the invention realizes compound synergism; liver and kidney nourishing efficacy of eucommia male flower, food retention removing, stagnation transforming, spleen invigorating and stomach strengthening efficacies of hawthorn, and the wind dispelling, heat clearing, liver clearing and eyesight improving efficacies of mulberry leaf are complementary, so as to realize more outstanding health care functions.

Description

A kind of eucommia Bark male flower beverage
Technical field
The present invention relates to beverage, be specifically related to a kind of eucommia Bark male flower beverage anti-ageing, fatigue-resisting function that has.
Background technology
Along with developing rapidly of modern society, people not only will bear the multiple pressure of the each side such as study, work, life, and, because environmental pollution is day by day serious, many people are in " inferior health " state, and main manifestations is that immunity of organisms descends, susceptible fatigue etc.Medical research shows, the mankind 99% disease is all relevant with immune system, therefore, wants prophylactic generation, the physique of keeping fit, and it is crucial improving immunity.Often the crowd's body immune system function under fatigue state can constantly go down simultaneously, and how alleviating and eliminating fatigue also becomes the major issue that improves immunity.
Modern immunology thinks, immunity is body identification and removes nonself macromolecular complex, and the physiological reaction of holder internal and external equilibrium, i.e. a kind of process of body to the identification of " non-oneself " material, eliminating, elimination.The immunologic function of human body is one defence line, is escorting health; Be again a kind of ability of getting rid of illness, after the people is ill, can promote rehabilitation, this just becomes human body and keeps fit disease-resistant basic place.Yet, in daily life, have many factors body immunity is descended or immunologic derangement occurs.Such as, meals are unreasonable, protein, vitamin, micro-insufficiency of intake; Live irregular, do not have enough sleep; The exercise that lacks exercise, poor to the adaptive capacity of environment; Stress, overworked; Use the bad reaction of hormone, antibiotic etc, suppressed immunity; Temporarily reduced immunity while suffering from acute disease, while suffering from chronic diseases for a long time in hypoimmunity state etc.
Fatigue is also one of the principal element of 21 century harm humans health.At society, because rhythm of life is accelerated, a lot of people are bearing larger psychological pressure or for a long time in overtime excess load work state, as unreasonable rest, adjusting, if things go on like this, the vitals function of health will be lacked of proper care, thereby causes the generation of a series of fatigue symptoms such as burnout, giddy, headache, limbs fatigue, listless, failure of memory.Fatigue can cause that oxygen radical gathers, immunologic hypofunction etc., if eliminate not in time, disease will be comed one after another in the course of time, has a strong impact on people's work and life.According to World Health Organization investigation, approximately there is people more than 35% in the whole world in fatigue state, and especially middle-aged male crowd fatigue state person is up to 60%-75%.The medical expert points out, continues overtiredly can cause a series of ill symptomses, produces " burnout syndrome ".
If long-time hypoimmunity or, in fatigue state, human body just there will be the intermediateness-sub-health state of healthy and disease.And sub-health state is continuous Change and Development, as do not improved in time, probably to morbid state, transform.So, improve human body autoimmune function, alleviating physical fatigue, be away from inferior health, move towards healthy basic method.The relevant survey data of China shows, crowd more than 60% arranged in sub-health status, only relies on the medicine symptomatic treatment to be difficult to return to the normal health state.And the center of gravity of modern medicine turns to the intervention of state before sick and effective strick precaution of disease, traditional Chinese medicine shows unique characteristics in the adjustment to the animal economy functional status, take to have the health food that the Chinese medicine that improves immunity and alleviating physical fatigue function is raw material potential advantage is arranged.
The health food with enhancing immunity and alleviating physical fatigue of selling in the market is more, mainly with individual event enhancing immunity or individual event alleviating physical fatigue, be main, but hypoimmunity and fatiguability interknits.The imbalance of human body autoimmune function, immunity degradation there will be the sub-health states such as physical fatigue, and can cause immunity degradation in fatigue state for a long time.
Although some folium cortex eucommiaes, bark of eucommia jasmine tea etc. have occurred at present, its component is too simple, poor effect, and adopt the form of tealeaves to exist, when soaking, active ingredient can not be soaked out fully, causes the waste of active ingredient.Therefore a kind of antifatigue of necessary exploitation, to strengthen the immunity effect more outstanding, and the beneficiating ingredient of the bark of eucommia is utilized to health products more fully.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of eucommia Bark male flower beverage, and it has the immunity of enhancing and alleviating physical fatigue double action, thereby eliminates defect in the above-mentioned background technology.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of eucommia Bark male flower beverage comprises the raw material of following weight portion:
Figure BDA0000392349500000021
As a kind of improvement, add steviol glycoside 0.3～0.4 weight portion in described eucommia Bark male flower beverage, thereby prepare Sugarless type eucommia Bark male flower beverage.
As a kind of improvement, add white granulated sugar in described eucommia Bark male flower beverage, 5wt%～7wt% that described white sugar content is eucommia Bark male flower, honeysuckle, mulberry leaf and hawthorn gross weight, thus make sugar-containing type eucommia Bark male flower beverage.
As a kind of improvement, described eucommia Bark male flower beverage is preferably the raw material of following weight portion:
Figure BDA0000392349500000031
The preparation method of Sugarless type eucommia Bark male flower beverage of the present invention is as follows:
S1, weighing 4～6 weight portion eucommia Bark male flowers, and utilize ultrasonic wave to extract, obtain the ultrasonic wave extract;
S2, weighing 6～8 weight portion honeysuckles, 6～8 weight portion mulberry leaf and 3～5 weight portion hawthorn, boiling twice adds the water of honeysuckle, mulberry leaf and 14 times of amounts of hawthorn gross weight at every turn, and each decocts 1 hour, extracts filtrate filtration, merging filtrate;
S3, the liquid in step S1 and S2 is merged, then add wherein steviol glycoside 0.3～0.4 weight portion to stir evenly, add purified water to gross weight 1000 weight portions.
Of the present invention have the preparation method of sugared type eucommia Bark male flower beverage as follows:
S1, weighing 4～6 weight portion eucommia Bark male flowers, and utilize ultrasonic wave to extract, obtain the ultrasonic wave extract;
S2, weighing 6～8 weight portion honeysuckles, 6～8 weight portion mulberry leaf and 3～5 weight portion hawthorn, boiling twice adds the water of honeysuckle, mulberry leaf and 14 times of amounts of hawthorn gross weight at every turn, and each decocts 1 hour, extracts filtrate filtration, merging filtrate;
S3, the liquid in step S1 and S2 is merged, then adds wherein 5wt%～7wt% that white granulated sugar, described white sugar content are eucommia Bark male flower, honeysuckle, mulberry leaf and hawthorn gross weight,, add purified water to gross weight 1000 weight portions.
Then beverage is filtered, embedding, sterilizing, check, packing, obtain the eucommia Bark male flower beverage.
In the present invention, the male flower pistil that eucommia Bark male flower is the bark of eucommia (the male tree of bark of eucommia genitals).The bark of eucommia is Chinese famous and precious tonic herb.Tool filling liver kidney, strengthening the bones and muscles, many effects such as hypotensive, antiabortive.Shennong's Herbal is classified as top grade.And eucommia Bark male flower, contain lignin, iridoids, Phenylpropanoid Glycosides class active skull cap components (as Geniposidic acid, chlorogenic acid, Aucubin), rosin spirit disaccharide glucoside, flavones (Quercetin), amino acid, polysaccharide and mineral element Zn, Mn, Cu, Fe, Ca, P, B, Mg, K etc.Wherein amino acid content reaches 21.47%, and the content of calcium reaches 0.92%, and zinc content reaches 51mg/100g.General flavone content in eucommia Bark male flower is 5-7.3 times of Bark of Eucommia Ulmoides, and chlorogenic acid content is 2.7-4 times of Bark of Eucommia Ulmoides; Several Major constituent contents such as calcium, phosphorus, potassium, sodium, magnesium are 2.3 times of Bark of Eucommia Ulmoides, and iron, zinc, copper, manganese, selenium and other trace elements content are 7.1 times of Bark of Eucommia Ulmoides; 10 seed amino acid content of needed by human reach 9.69g/100g, are 4.82 times of Bark of Eucommia Ulmoides, and in eucommia Bark male flower, the essential amino acid proportioning almost approaches or exceeds the mode standard value that FAO/WHO recommends, and is rare healthy treasure.Scientific research is found: " eucommia Bark male flower " is special containing the effective plant component of kind more than 60, as lignin, iridoids, Phenylpropanoid Glycosides class active material is (as Geniposidic acid, chlorogenic acid, Aucubin), rosin spirit disaccharide glucoside, flavones, alkaloid, amino acid, polysaccharide and mineral element Zn, Mn, Cu, Fe, Ca, P, B, Mg, K etc., wherein amino acid content reaches 21.47%, the content of calcium reaches 0.92%, zinc content reaches 51mg/100g, respectively 1.8 times and 5.2 times of folium cortex eucommiae, active ingredient is the most comprehensive, and content is higher, eucommia Bark male flower, the elite of having collected all barks of eucommia, can say that eucommia Bark male flower possesses all health-care efficacies of the plant bark of eucommia, and for " strong liver, kidney tonifying, defaecation, sleep peacefully, three height fall " effect particularly remarkable.Modern pharmacological research shows, the water decoction increase phagocyte activity of eucommia Bark male flower, and the non-specific immune function of enhancing body, have dual regulation to cellular immune function.
Mulberry leaf in the present invention are one of China's conventional medicaments, belong to the medicine-food two-purpose article.In recent years, the various countries scholar has carried out large quantity research to mulberry leaf, and especially Japan, from nineteen ninety, has started " exploitation does not utilize food material " research project, and mulberry leaf function and process technology thereof are conducted in-depth research.The a lot of experts of China have also carried out the research of chemical composition and pharmacologically active aspect, find that mulberry leaf nutrient is worth very high, contain various bioactivators.In recent years, mulberry leaf exploitation heat has been risen in Japan, Korea S, and its people have been risen the upsurge of one edible mulberry leaf.China has also started the exploitation of mulberry leaf products, utilize at present the food of mulberry leaf development a lot, comprise bread and cheese, health food, beverage, flavouring etc., the product of having developed has Mulberry-leaf Tea (6g/ day), mulberry leaf powder, and (a kind of is that former mulberry leaf are pulverized for end, by 200 mesh sieves; Another kind is the mulberry leaf extracts) and mulberry leaf juice beverage, mulberry leaf ice cream, mulberry leaf instant tea, mulberry leaf cola, mulberry leaf carbonated drink, mulberry leaf mixed congee, mulberry leaf are brilliant, mulberry leaf can take liquid, mulberry leaf pearl powder honey, mulberry leaf pollen honey, mulberry leaf dried noodles, mulberry leaf bean curd, mulberry leaf biscuit, mulberry leaf bean powder, mulberry leaf wine, mulberry leaf ham sausage, mulberry leaf vinegar, mulberry leaf sauce etc.; Also rise at present with mulberry leaf as animal feed or feed addictive, rear cattle (improving the cow milk yield), exempt from, deer, fish etc., effect is fine.Rutin sophorin in mulberry leaf, Quercetin, quercitin can increase convergent force and the output quantity of in vitro and the frog heart in place, and reduce heart rate.Rutin sophorin makes toad lower limb and rabbit ear vessel retraction, and the expansible coronary vasodilator of Quercetin improves the cardiac muscle circulation.GABA, rutin sophorin, quercitrin have hypotensive effect.Wherein alpha-aminobutyric acid content is very high, up to 226mg/100g, noticeable.GABA is the neural material of passing on, and can promote the metabolism of brain tissue and recover function of brain cell, simultaneously, can improve brain blood and flow, and strengthens the activity of Angiotensin-Converting I, impels blood pressure drops.Rutin sophorin in mulberry leaf, Quercetin, quercitin can increase convergent force and the output quantity of in vitro and the frog heart in place, and bibliographical information is arranged, and isolate the various active composition as flavones and derivative thereof from mulberry leaf, confirm the step-down of mulberry leaf energy.Mulberry leaf have the formation that suppresses fatty liver, the effect that reduces serum fat and inhibition atherogenesis.Active component comprises DNJ, phytosterol, flavonoids etc.Hyperlipidemia patient's blood viscosity is high, flowing in capillary is very not smooth, capillary very easily stops up, low-density lipoprotein (LDL-C) oxidation is the major reason that causes circulation system disease, oxidation lipoprotein is deposited on blood vessel can make lumen of vessels narrow down, even stop up, myocardial infarction and cerebral hemorrhage are all the results that capillary stops up.Contain the strengthening capillary in mulberry leaf, reduce the flavones ingredient of blood viscosity, another Mulberry-leaf Tea contains the composition of LDL-lipoprotein oxidation in antibody, so mulberry leaf have again the effect of prevention myocardial infarction and cerebral hemorrhage when fat-reducing, improving hyperlipidemia.The good generation confirmation of Japan expert soil well, the hyperlipidemia serum lipids is raise mulberry-leaf extract and atherosclerotic has inhibitory action.High ridge report, Mulberry-leaf Tea makes hyperlipidemia rats serum high-density LP (HDL-C), HDL-C/TC obviously raise (p<0.05), T-CHOL (TC), LDL-C, triacylglycerol (TG) obviously reduce (p<0.05), lipid peroxide (LPO) significantly reduces (p<0.001), illustrate that Mulberry-leaf Tea can reduce blood fat, softening blood vessel, removing body endoperoxide, thereby the rising of hyperlipidemia serum lipids and atherosclerotic are had to inhibitory action.Since ancient times, the traditional Chinese medical science just is applied to clinical using mulberry leaf as the Chinese medicine for the treatment of diabete (being the diabetes of modern medicine), and Japanese ancient book " eating tea health note " is also put down in writing the effect that mulberry leaf are improved " drinking-water is sick " (being the diabetes of modern medicine).The studying data at home and abroad confirmation, alkaloid and polysaccharide are blood sugar reducing components main in mulberry leaf.In recent years, large quantity research shows that the hypoglycemic activity of mulberry leaf realizes by two approach: the one, by alkaloid DNJ(1-DNJ) to the active generation of disaccharides catabolic enzyme inhibitory action, thereby suppress the absorption of small intestine to disaccharide, reduce the peak value of the rear blood sugar of food; The 2nd, Folium Mori alkaloid fagomine and mulberry leaf polysaccharide promote that the β cell divides must insulin, and insulin can promote cell to close sugared utilization, hepatic glycogen or and improve glycometabolism, finally reach hypoglycemic effect.Asano etc. have compared isolated 7 kinds of alkaloidal hypoglycemic activities from mulberry leaf, find that the polyhydroxy norhyoscyamine has very strong glycosidase inhibiting function; Kimura M etc. has observed the diabetic mice hypoglycemic activity that above 7 kinds of alkaloids cause STZ, experimental result shows, N-Me-DNJ, GAL-DNJ and fagomine can reduce blood sugar level significantly, wherein GAL-DNJ and fagomine hypoglycemic activity are the strongest, in plant only mulberry leaf contain this alkaloid of GAL-DNJ (this be the advantageous natural active matters of mulberry leaf, other plant is not all containing this class material in the world), it is a kind of inhibitor of glycosidase, and soluble in water, easily be absorbed by the body.Fan Lisheng found through experiments white mulberry vein-juice has good inhibition growth to most of gram positive bacterias and gram-negative bacteria and part saccharomycete.And required Mlc is low, pH value scope is 4～9, heat endurance is strong.Rutin sophorin can significantly suppress the Rat Models of Traumatic edema, and can stop the development of conjunctivitis, auricle inflammation, pulmonary edema.Mulberry leaf can prevent cancer cell to generate, and improve body immunity, and the major function composition comprises it being DNJ, flavonoids, Sang Su, SOD, GABA and vitamin, can suppress chromosome mutation and gene mutation.1-DNJ (DNJ) is a kind of alkaloid in mulberry leaf, and clinical testing proof DNJ has the effect of significant anti-reverse transcription enzymophathy cytotoxic activity, and its IG30 is 1.2-2.5 μ g/mL, and, with the increase of DNJ dosage, its restraint strengthens.Mouse β-16 lung black cell the tumour of take is model, the derivative relevant to 1-nojirimycin A and the activity of resisting tumor metastasis of analog thereof have been studied, point out that DNJ is the analogue of nojirimycin, it is 80.5% to the inhibiting rate of metastases, it suppresses mechanism: DNI produces immature carbohydrate chain by the activity that suppresses glycosidase at tumor cell surface, has weakened the transfer ability of tumour.Two kinds of flavonoids of separation and purification in the discovery mulberry leaf such as Korea scholar Kim-food in one's mouth bucket skin element-3-β-D glucopyranoside and Quercetin-3-7-dioxy-β-D-glucopyranoside reveal significant depression effect to the growth table of human promyelocytic leukemia cell (HL-60), and its latter has also induced the differentiation of HL-60 cytokine.Sang Su in mulberry leaf has active anticancer, and the vitamin in mulberry leaf has the other mutagen effect of pressing down.In mulberry leaf, the compositions such as contained Quercetin, phenolic compound, vitamin C can be by suppressing or remove free radical to prevent oxidative damage.The reports such as Huang Dong, mulberry leaf have help and the effect anti-ageing, that stablize nervous function of similar ginseng, can alleviate excited that physiological change causes, improve the activity of superoxide dismutase in body, stop the generation of harmful substance in body, reduce or eliminate the lipofuscin that produces and stagnate in body.Tang Fadi etc. adopt anti-stress, anti-fatigue test, aged rats SOD and lipofuscin are measured, and the life span of drosophila melanogaster test confirms that mulberry leaf can improve mouse to the tolerance of high temperature stimulation and prevent that the Rat Adrenal Cortex distributed function caused due to stress stimulation is low, and, when adrenal function is low, it is normal that mulberry leaf can make it to recover.With dexamethasone, make mouse produce " exhaustion ", mulberry leaf can alleviate the generation of this phenomenon.Mulberry leaf can extend mouse swimming and transfer rod time, have the body of enhancing Endurence.Mulberry leaf can extend the life-span of fruit bat, can improve SOD content in the senile rat red blood cell, thereby can effectively remove the superoxide anion that biological oxidation produces, and can reduce senile rat brain, myeloid tissue's content, show to have the effect delayed senility.DNJ. after in mineral matter and small intestine, unabsorbed carbohydrate enters large intestine, by the intestinal flora effect, cause fermentation; produce the organic acids such as butyric acid, propionic acid, lactic acid, acetic acid; make environment in intestines become acidity; intestinal contents acidity increases; the propagation that can suppress harmful bacteria; play regulating intestinal canal, improve constipation, improve the effect of belly sensation of fullness, therefore there is the catharsis defaecation, reduce the generation of some acute abdomen, the effects such as protection intestinal mucosa and fat-reducing.
Honeysuckle in the present invention is cold in nature, distinguishes the flavor of sweet, enters lung, the heart, stomach warp, has the effect that clearing heat and detoxicating, anti-inflammatory, qi-restoratives are treated wind, cures mainly disease under turgor, warm disease heating, the diseases such as hot malicious large carbuncle and tumour.It is dizzy for giddy, dry is done yearningly, the illnesss such as hidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis, epidemic meningitis, acute mastitis, septicemia, appendicitis, skin infection, ulcer furunculosis, erysipelas, mumps, suppurative tonsillitis all have certain curative effect.Lonicera flower tea has unique weight losing function simultaneously, can also suppress and the pathogen of killing bottleneck throat, and old man and children are had to anti-infective effect.So, often take honeysuckle immersion or decoction and be conducive to wind fire hot eyes, abscess of throat, obesity, liver heat symptom-complex and the hypertensive treatment of liver pattern of fever and rehabilitation.Honeysuckle is containing inositol, flavonoids, inositol, saponin and tannin etc., there is broad-spectrum antibacterial action, the various pathogens such as staphylococcus aureus, shigella dysenteriae are all had to stronger inhibitory action, the multiple pathogenic microorganisms such as Leptospira, influenza virus and pathogenic moulds are also had to inhibitory action.In addition, honeysuckle also has obvious anti-inflammatory and refrigeration function, and honeysuckle water and steeping in wine liquid have obvious lethal effect to tentative tumour cell.
In the present invention, hawthorn is fruit, is again medicine, belongs to the medicine-food two-purpose article.Its main active substances has flavonoids (Quercetin, hyperin etc.), triterpenes (ursolic acid, oleanolic acid, crataegolic acid), chlorogenic acid, OPC (Procyanidins, be called for short PC, and two～tetramer is called for short OPC) etc.Hawthorn energy prevention and cure of cardiovascular disease, have hemangiectasis, increase CF, improve the heart vigor, the stimulating central nervous system system, reduce blood pressure and cholesterol, softening blood vessel and diuresis and sedation; Crataegolic acid also has cardiotonic, also helpful to senile heart disease; Hawthorn contains the fatty lipolytic enzyme of a kind of energy digestion, and more tartaric acid, contributes to food digestion, helps lend some impetus to especially the digestion of meat food; Hawthorn has inhibitory action to shigella dysenteriae, staphylococcus aureus, Pseudomonas aeruginosa; Hawthorn energy appetite-stimulating indigestion-relieving, offset carnivorous stagnant effect better especially, has the slimming and removing fat effect.Hawthorn has the effect activated blood circulation and dispersed blood clots, and contributes to remove local extravasated blood state, and traumatic injury is had to auxiliary curative effect.In addition, hawthorn has contraction to uterus, and the effect expedited the emergence of is arranged just before giving birth the time the pregnant woman.And can promote the uterine involution in postpartum.The generation of free radical is blocked and reduced to the flavonoids that hawthorn is contained and the substances such as vitamin C, carrotene, can strengthen the immunity of body, and anti-aging, anticancer effect is arranged.In hawthorn, having relievings asthma reduces phlegm, the composition of anti-bacteria, treatment abdominal pain diarrhea.The Tianjin IEM is measured the antioxidation activity of domestic common 30 kinds of fruit, and result shows the taking the first place of hawthorn anti-aging effects.Hawthorn has the merit of relieving the effect of alcohol and reducing phlegm, and pharmacological research proves, hawthorn can increase the gastric juice digestive ferment, promotes ethanol decomposition.The Vit C contents of hawthorn very high (89mg/100g) is 10 times of apple.Because hawthorn is rich in multiple organic acid, it can keep the vitamin C in hawthorn, even heating is also unlikely destroyed.The carotene carotene content of hawthorn is 9 times of apple, and vitamin B2 is 5 times of apple, and the content of calcium also comes out at the top in fresh fruit, also contains the nutriments such as a large amount of crataegolic acids, tartaric acid, malic acid, citric acid and protein, fat, starch.In hawthorn, the pectin content shelter has first of fruit, reaches 6.4%, and it has the effect of radio-opaque substance, in body, can be with the radioactive element (strontium, cobalt, palladium etc.) of walking half.Be rich in OPC in hawthorn, OPC has extremely strong antioxidation activity, is a kind of good free radical scavenger and lipid peroxidation inhibitor; And can harmful enzyme produce powerful inhibitory action, and there is antimutagenicity and anti-inflammatory activity, can treat the SH of rat and be dose-effect relationship, suppress platelet aggregation, reducing blood lipid, the effect such as antiviral, anticancer.
In sum, eucommia Bark male flower, mulberry leaf, honeysuckle, hawthorn have the functions such as hypotensive, reducing blood lipid, prevention cerebral thrombus and miocardial infarction that the effect direction is consistent, hypoglycemic, anti-ageing, antifatigue, enhancing immunity of organism.Therefore the stack of four flavor effects, have the compound synergistic effect; And long-pendingization that disappear of the filling liver kidney of eucommia Bark male flower and hawthorn is stagnant, tonifying spleen stomach strengthening function and the wind and heat dispersing of mulberry leaf, the function of clearing liver and improving vision reach again complementation, causes health care more outstanding.
The present invention adopts specific preparation method to be prepared into the form of beverage, and its characteristics have: 1. beverage is easy to absorption of human body, and drinks conveniently; 2. the amount of drinking is large, in its peculiar function of performance, also can supplement the moisture that human body needs; 3. the simple easy operating of technique, be beneficial to suitability for industrialized production, and can retain preferably the active ingredient in medicinal material; 4. it is drunk pattern and is easily accepted by the consumer, and compliance is good; 5. adopt the can packing, seal degree is good, and can adopt the sterilizing measure, is difficult for polluting again, is conducive to preserve.
Owing to having adopted technique scheme, the invention has the beneficial effects as follows:
Eucommia Bark male flower beverage provided by the invention, adopt eucommia Bark male flower, mulberry leaf, honeysuckle, four kinds of components of hawthorn, and there is the functions such as hypotensive, reducing blood lipid, prevention cerebral thrombus and miocardial infarction that the effect direction is consistent, hypoglycemic, anti-ageing, antifatigue, enhancing immunity of organism.Therefore the stack of four flavor effects, have the compound synergistic effect; And long-pendingization that disappear of the filling liver kidney of eucommia Bark male flower and hawthorn is stagnant, tonifying spleen stomach strengthening function and the wind and heat dispersing of mulberry leaf, the function of clearing liver and improving vision reach again complementation, cause antifatigue and strengthen the health care of immunity more outstanding.
And the inventor finds in experiment, when adopting eucommia Bark male flower, mulberry leaf, honeysuckle, hawthorn composition reasonably to arrange in pairs or groups, not only have antifatigue concurrently, strengthen the function such as immunity of organism, and two kinds of functions have obtained reinforcement to a certain degree, this is that inventor institute is not foresighted.This also illustrates, when eucommia Bark male flower, mulberry leaf, honeysuckle, hawthorn composition are reasonably arranged in pairs or groups, is not only the simple superposition of function, but has played joint action of potentiation, has each other complementation.
The specific embodiment
For technological means, creation characteristic that the present invention is realized, reach purpose and effect is easy to understand, below in conjunction with specific embodiment, further set forth the present invention.
Embodiment 1
A kind of eucommia Bark male flower beverage comprises following raw material:
Figure BDA0000392349500000091
And adding man-hour, add steviol glycoside 0.3g, thereby prepare Sugarless type eucommia Bark male flower beverage.
The detailed step of preparation is as follows:
S1, weighing 4g eucommia Bark male flower, and utilize ultrasonic wave to extract, obtain the ultrasonic wave extract;
S2, weighing 6g honeysuckle, 8g mulberry leaf and 5g hawthorn, boiling twice adds the water of honeysuckle, mulberry leaf and 14 times of amounts of hawthorn gross weight at every turn, and each decocts 1 hour, extracts filtrate filtration, merging filtrate;
S3, the liquid in step S1 and S2 is merged, then add wherein steviol glycoside 0.3g, stir evenly, add purified water to gross weight 1000g.
Then beverage is filtered, embedding, sterilizing, check, packing, obtain Sugarless type eucommia Bark male flower beverage.
Embodiment 2
A kind of eucommia Bark male flower beverage comprises following raw material:
And adding man-hour, add steviol glycoside 0.4g, thereby prepare Sugarless type eucommia Bark male flower beverage.
The detailed step of preparation is as follows:
S1, weighing 6g eucommia Bark male flower, and utilize ultrasonic wave to extract, obtain the ultrasonic wave extract;
S2, weighing 8g honeysuckle, 6g mulberry leaf and 3g hawthorn, boiling twice adds the water of honeysuckle, mulberry leaf and 14 times of amounts of hawthorn gross weight at every turn, and each decocts 1 hour, extracts filtrate filtration, merging filtrate;
S3, the liquid in step S1 and S2 is merged, then add wherein steviol glycoside 0.5g, stir evenly, add purified water to gross weight 1000g.
Then beverage is filtered, embedding, sterilizing, check, packing, obtain the eucommia Bark male flower beverage.
Embodiment 3
A kind of eucommia Bark male flower beverage comprises following raw material:
Figure BDA0000392349500000101
And adding man-hour, add steviol glycoside 0.3g, thereby prepare Sugarless type eucommia Bark male flower beverage.
Detailed preparation process is as follows:
S1, weighing 5g eucommia Bark male flower, and utilize ultrasonic wave to extract, obtain the ultrasonic wave extract;
S2, weighing 7g honeysuckle, 7g mulberry leaf and 4g hawthorn, boiling twice adds the water of honeysuckle, mulberry leaf and 14 times of amounts of hawthorn gross weight at every turn, and each decocts 1 hour, extracts filtrate filtration, merging filtrate;
S3, the liquid in step S1 and S2 is merged, then add wherein steviol glycoside 0.4g, stir evenly, add purified water to gross weight 1000g.
Then beverage is filtered, embedding, sterilizing, check, packing, obtain the eucommia Bark male flower beverage.
Embodiment 4
A kind of eucommia Bark male flower beverage comprises following raw material:
Figure BDA0000392349500000102
And, adding man-hour, add white granulated sugar, and the 7wt% that described white sugar content is eucommia Bark male flower, honeysuckle, mulberry leaf and hawthorn gross weight, thus make sugar-containing type eucommia Bark male flower beverage.
Detailed preparation method is as follows:
S1, weighing 6g eucommia Bark male flower, and utilize ultrasonic wave to extract, obtain the ultrasonic wave extract;
S2, weighing 8g honeysuckle, 8g mulberry leaf and 5g hawthorn, boiling twice adds the water of honeysuckle, mulberry leaf and 14 times of amounts of hawthorn gross weight at every turn, and each decocts 1 hour, extracts filtrate filtration, merging filtrate;
S3, the liquid in step S1 and S2 is merged, then add wherein the 7wt% that white granulated sugar, described white sugar content are eucommia Bark male flower, honeysuckle, mulberry leaf and hawthorn gross weight, stir evenly, add purified water to gross weight 1000g.
Then beverage is filtered, embedding, sterilizing, check, packing, obtain the eucommia Bark male flower beverage.
Embodiment 5
A kind of eucommia Bark male flower beverage comprises following raw material:
Figure BDA0000392349500000111
And work in-process, add white granulated sugar, the 5wt% that described white sugar content is eucommia Bark male flower, honeysuckle, mulberry leaf and hawthorn gross weight, thus make sugar-containing type eucommia Bark male flower beverage.
Detailed preparation method is as follows:
S1, weighing 4g eucommia Bark male flower, and utilize ultrasonic wave to extract, obtain the ultrasonic wave extract;
S2, weighing 6g honeysuckle, 6g mulberry leaf and 3g hawthorn, boiling twice adds the water of honeysuckle, mulberry leaf and 14 times of amounts of hawthorn gross weight at every turn, and each decocts 1 hour, extracts filtrate filtration, merging filtrate;
S3, the liquid in step S1 and S2 is merged, then add wherein the 5wt% that white granulated sugar, described white sugar content are eucommia Bark male flower, honeysuckle, mulberry leaf and hawthorn gross weight, stir evenly, add purified water to gross weight 1000g.
Then beverage is filtered, embedding, sterilizing, check, packing, obtain the eucommia Bark male flower beverage.
Embodiment 6
A kind of eucommia Bark male flower beverage comprises following raw material:
Figure BDA0000392349500000112
And, adding man-hour, add white granulated sugar, and the 6wt% that described white sugar content is eucommia Bark male flower, honeysuckle, mulberry leaf and hawthorn gross weight, thus make sugar-containing type eucommia Bark male flower beverage.
The preparation method is as follows in detail:
S1, weighing 5g eucommia Bark male flower, and utilize ultrasonic wave to extract, obtain the ultrasonic wave extract;
S2, weighing 7g honeysuckle, 7g mulberry leaf and 4g hawthorn, boiling twice adds the water of honeysuckle, mulberry leaf and 14 times of amounts of hawthorn gross weight at every turn, and each decocts 1 hour, extracts filtrate filtration, merging filtrate;
S3, the liquid in step S1 and S2 is merged, then add wherein the 6wt% that white granulated sugar, described white sugar content are eucommia Bark male flower, honeysuckle, mulberry leaf and hawthorn gross weight, stir evenly, add purified water to gross weight 1000g.
Then beverage is filtered, embedding, sterilizing, check, packing, obtain the eucommia Bark male flower beverage.
Embodiment 7
The selection of flavouring.In order to make product there is good mouthfeel when drinking, improve the drinking person compliance, therefore add flavouring, improved.Consider that the consumer groups such as diabetes, obesity also can drink this product, therefore Sugarless type eucommia Bark male flower beverage selects steviol glycoside to regulate mouthfeel.
Method:
Weighing 25g eucommia Bark male flower, and utilize ultrasonic wave to extract, obtain the ultrasonic wave extract; Weighing 35g honeysuckle, 35g mulberry leaf and 20g hawthorn, boiling twice adds the water of honeysuckle, mulberry leaf and 14 times of amounts of hawthorn gross weight at every turn, and each decocts 1 hour, extracts filtrate filtration, merging filtrate; Above-mentioned liquid is merged, be divided into 5 parts, add respectively the steviol glycoside of different proportion, and add purified water to gross weight 1000g.
Mouthfeel is investigated, be the results are shown in Table 1.
Table 1: flavouring is investigated situation
Figure BDA0000392349500000121
While as can be seen from Table 1, in 1000g solution, containing the 0.3-0.4g steviol glycoside, sugariness is moderate.0.5g if, mouthfeel is sweeter greasy, is not suitable as the Sugarless type beverage.
Embodiment 8
Eucommia Bark male flower beverage provided by the invention strengthens the research to immunity, anti-fatigue performance
Method:
By a mouse, random even minute in blank group, eucommia Bark male flower folk prescription group, honeysuckle folk prescription group, mulberry leaf folk prescription group, hawthorn folk prescription group and eucommia Bark male flower beverage group.
Eucommia Bark male flower folk prescription group: weighing 5g eucommia Bark male flower, ultrasonic wave extracts, then adds purified water to gross weight 1000g.
Honeysuckle folk prescription group: weighing 7g honeysuckle, boiling twice adds the water of 14 times of amounts of honeysuckle at every turn, and each decocts 1 hour, extracts filtrate filtration, then adds purified water to gross weight 1000g.
Mulberry leaf folk prescription group: weighing 7g mulberry leaf, boiling twice, the water of each 14 times of amounts of mulberry leaf weight, each decocts 1 hour, extracts filtrate filtration, then adds purified water to gross weight 1000g.
Hawthorn folk prescription group: weighing 4g hawthorn, boiling twice adds the water of 14 times of amounts of hawthorn weight at every turn, and each decocts 1 hour, extracts filtrate filtration, then adds purified water to gross weight 1000g.
Eucommia Bark male flower beverage group: the beverage that adopts embodiment 2 preparations.
The grouping of table 2 experimental animal
Sequence number Group Quantity Dosage
1 The blank group 20 Physiological saline, every day, gavage 500g, divided 2 times
2 Eucommia Bark male flower folk prescription group 20 Every day, gavage 250g, divided 2 times
3 Honeysuckle folk prescription group 20 Every day, gavage 250g, divided 2 times
4 Mulberry leaf folk prescription group 20 Every day, gavage 250g, divided 2 times
5 Hawthorn folk prescription group 20 Every day, gavage 250g, divided 2 times
6 Eucommia Bark male flower beverage group 20 Every day, gavage 250g, divided 2 times
According to the dosed administration in table 2.Then every group mouse is divided at random to 2 groups (10 one groups) and carries out respectively immunity mensuration and anti-fatigue test.
Immunity is measured:
The t lymphocyte subset group is the important cells that forms the immunity of organism system of defense.Modern immunology viewpoint is thought, the number of T cell subsets and CD4 in peripheral blood +/ CD8 +ratio is one of parameter of estimating the optimum meaning of Organism immunoregulation poised state, and therefore, the present embodiment selects this index as immunity is measured.
After successive administration 7 days, get peripheral blood and detected with flow cytometer, statistics is as table 2, and in table 2, numerical value is mean value.
Table 2
Sequence number Group CD4 +（%） CD8 +（%） CD4 +/CD8 +
1 The blank group 44.95 20.43 2.20
2 Eucommia Bark male flower folk prescription group 56.86 15.38 3.70
3 Honeysuckle folk prescription group 51.91 19.87 2.61
4 Mulberry leaf folk prescription group 49.12 19.91 2.47
5 Hawthorn folk prescription group 45.24 20.33 2.23
6 Eucommia Bark male flower beverage group 64.57 13.10 4.93
From table 2, with the blank group, to compare, all the other experimental group all can improve CD4 +/ CD8 +ratio.Wherein, eucommia Bark male flower folk prescription group, honeysuckle folk prescription group promote larger, although and mulberry leaf folk prescription group, hawthorn folk prescription group are improved, amplitude is little.And eucommia Bark male flower beverage group provided by the invention can greatly improve CD4 +/ CD8 +ratio.
After successive administration 20 days, measure antibody-producting cell number in spleen.Statistics is as table 3, and in table 3, numerical value is mean value.
Table 3
Sequence number Group Antibody-producting cell number/10 6
1 The blank group 195.07
2 Eucommia Bark male flower folk prescription group 208.41
3 Honeysuckle folk prescription group 212.53
4 Mulberry leaf folk prescription group 198.37
5 Hawthorn folk prescription group 196.01
6 Eucommia Bark male flower beverage group 381.43
From table 3, with the blank group, compare, except mulberry leaf folk prescription group, hawthorn folk prescription group antagonist cellulation number improve not quite, eucommia Bark male flower folk prescription group, honeysuckle folk prescription group and eucommia Bark male flower beverage group antagonist cellulation number have obvious raising, and the raising of eucommia Bark male flower beverage group antagonist cellulation number especially provided by the invention has very significant effect.
Therefore, eucommia Bark male flower beverage composition minute provided by the invention plays good joint action of potentiation, has greatly improved CD4 +/ CD8 +ratio and antibody-producting cell number, can improve immunity of organisms.
Anti-fatigue test
Successive administration 5 days, after last administration 1 hour, after bearing a heavy burden (body weight 10%), mouse tail drops into the water went swimming of 25 ℃, observe and record mouse and within 7 seconds, can not swim out of the time of the water surface as the swimming exhaustion time from dropping in water to the head submerged, statistics is as table 4, and the data in table 4 are mean value.
Table 4
Sequence number Group The swimming exhaustion time (min)
1 The blank group 15.24
2 Eucommia Bark male flower folk prescription group 23.43
3 Honeysuckle folk prescription group 17.30
4 Mulberry leaf folk prescription group 24.51
5 Hawthorn folk prescription group 15.74
6 Eucommia Bark male flower beverage group 28.76
From table 3, with the blank group, compare, except hawthorn folk prescription group is little to the raising of swimming exhaustion time, eucommia Bark male flower folk prescription group, honeysuckle folk prescription group, mulberry leaf folk prescription group, eucommia Bark male flower beverage group all have raising in various degree to the swimming exhaustion time.Especially eucommia Bark male flower beverage group provided by the invention has very significant effect to the raising of swimming exhaustion time.
Therefore, eucommia Bark male flower beverage composition minute provided by the invention plays good joint action of potentiation, and the time is exhausted in the swimming that has greatly extended mouse, can improve the anti-fatigue performance of body.
The present invention is not limited to the above-mentioned specific embodiment, and all are based on technical conceive of the present invention, and the structural improvement of having done, all fall among protection scope of the present invention.

Claims (6)

1. an eucommia Bark male flower beverage is characterized in that: the raw material that comprises following weight portion:
Figure FDA0000392349490000011
2. a kind of eucommia Bark male flower beverage as claimed in claim 1 is characterized in that: the raw material that comprises following weight portion:
Figure FDA0000392349490000012
3. a kind of eucommia Bark male flower beverage as claimed in claim 1 or 2, is characterized in that: add steviol glycoside 0.3～0.4 weight portion in described eucommia Bark male flower beverage, thereby prepare Sugarless type eucommia Bark male flower beverage.
4. a kind of eucommia Bark male flower beverage as claimed in claim 1 or 2, it is characterized in that: in described eucommia Bark male flower beverage, add white granulated sugar, 5wt%～7wt% that described white sugar content is eucommia Bark male flower, honeysuckle, mulberry leaf and hawthorn gross weight, thus make sugar-containing type eucommia Bark male flower beverage.
5. a kind of eucommia Bark male flower beverage as claimed in claim 3, it is characterized in that: the preparation method is as follows:
S1, weighing 4～6 weight portion eucommia Bark male flowers, and utilize ultrasonic wave to extract, obtain the ultrasonic wave extract;
S2, weighing 6～8 weight portion honeysuckles, 6～8 weight portion mulberry leaf and 3～5 weight portion hawthorn, boiling twice adds the water of honeysuckle, mulberry leaf and 14 times of amounts of hawthorn gross weight at every turn, and each decocts 1 hour, extracts filtrate filtration, merging filtrate;
S3, the liquid in step S1 and S2 is merged, then add wherein steviol glycoside 0.3～0.4 weight portion to stir evenly, add purified water to gross weight 1000 weight portions.
6. a kind of eucommia Bark male flower beverage as claimed in claim 4, it is characterized in that: the preparation method is as follows:
S1, weighing 4～6 weight portion eucommia Bark male flowers, and utilize ultrasonic wave to extract, obtain the ultrasonic wave extract;
S2, weighing 6～8 weight portion honeysuckles, 6～8 weight portion mulberry leaf and 3～5 weight portion hawthorn, boiling twice adds the water of honeysuckle, mulberry leaf and 14 times of amounts of hawthorn gross weight at every turn, and each decocts 1 hour, extracts filtrate filtration, merging filtrate;
S3, the liquid in step S1 and S2 is merged, then adds wherein 5wt%～7wt% that white granulated sugar, described white sugar content are eucommia Bark male flower, honeysuckle, mulberry leaf and hawthorn gross weight,, add purified water to gross weight 1000 weight portions.
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Publication number Priority date Publication date Assignee Title
CN105614800A (en) * 2015-12-22 2016-06-01 陕西今正蜂业有限公司 Eucommia ulmoides male flower honey and preparation technology thereof
CN105961962A (en) * 2016-03-22 2016-09-28 安徽培林食品科技有限公司 Honey peach sports drink
CN108324746A (en) * 2018-05-02 2018-07-27 冯显春 A kind of medicine materical crude slice and preparation method thereof that preventives treatment of disease made of Cordyceps militaris and eucommia Bark male flower
CN108713746A (en) * 2018-05-31 2018-10-30 南京中生生物科技有限公司 A kind of integration of drinking and medicinal herbs composition and its preparation method and application
CN110150389A (en) * 2019-05-30 2019-08-23 成都中医药大学 A kind of eucommia Bark male flower Manufacture of Walnut Milk and its preparation method and application
CN110680850A (en) * 2019-12-02 2020-01-14 黑龙江中医药大学 Traditional Chinese medicine health product for reducing blood fat
CN112205559A (en) * 2020-10-20 2021-01-12 山东贝隆杜仲生物工程有限公司 Composition containing eucommia ulmoides and mulberry leaves and application

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