CN103463542B - Application of edible vinegar as liquor for removing scars and changing skin, liquor for removing scars and changing skin and preparation method of liquor - Google Patents
Application of edible vinegar as liquor for removing scars and changing skin, liquor for removing scars and changing skin and preparation method of liquor Download PDFInfo
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- CN103463542B CN103463542B CN201310438275.9A CN201310438275A CN103463542B CN 103463542 B CN103463542 B CN 103463542B CN 201310438275 A CN201310438275 A CN 201310438275A CN 103463542 B CN103463542 B CN 103463542B
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Abstract
The invention discloses application of edible vinegar as a liquor for removing scars and changing skin, the liquor for removing scars and changing skin and the preparation method of the liquor. The liquor for removing scars and changing skin is prepared from the following raw materials by weight percent: 8-12% of salicylic acid, 18-22% of rhizoma galangae and 68-72% of edible vinegar. The preparation method of the liquor comprises the following steps: A, smashing, namely choosing out the rhizoma galangae according to the ratio and smashing into fine particles; B, soaking, namely weighing the salicylic acid according to the ratio, and then putting into the edible vinegar weighed according to the ratio to soak for 28-32 days together with the rhizoma galangae in the step A, and then filtering out residue to prepare the liquor, concentrating the liquor to 88-92%, so as to obtain the product liquor. According to the liquor, just a simple formula and available raw materials are selected. Compared with the prior art, the preparation method is easier to implement, low in cost, and easy to be accepted by a sufferer. The liquor has a function of removing the scars, and is fast to take effect, high in recovery rate, free of toxic and side effects and good in safety.
Description
Technical field
The invention belongs to tcm field, be specifically related to a kind of edible white vinegar and change the application of skin as scar of dispelling and scar of dispelling changes skin medicinal liquid.
Background technology
People in daily life, work because of scald, fire burn, scratch, explosive injury, get injured by a fall, the reasons such as wound, motor exhaust of performing the operation leave over lower various cicatrix on human body surface.Cicatrix be the detrimental effect of the factors such as physics, biology, chemistry in human body skin soft tissue, cause the major injury of skin soft tissue and can not normally repair completely voluntarily, turning the local symptom that stays after being repaired by fibrous tissue replacement.Cicatrix not only affects outward appearance but also affect function, and what bring to patient is the painful and psychic pain of the huge human body.
The mode of the main Applied Physics of current doctor trained in Western medicine, medicine, laser or operation removes cicatrix, conventional several treating acne methods are that excision cicatrix noinvasive is sewed up, cicatrix is repaired after soft tissue expander's expansion normal skin, drug injection in cicatrix, cicatrix attrition, the methods such as external mercurial, can improve outward appearance, alleviate scar hyperplasia.But above therapeutic scheme operating technology is complicated, and cost is higher, and too high medicine valency can make some patients because of financial insolvency expenses for medicine abandoning cure; Reagent combination is complicated, although consider the every aspect of hindering and should be noted, owing to not strengthening drug effect to the aspect needing most treatment, and make the recovery of wound, healing slows down, take effect slow; External mercurial has certain toxic and side effects, has certain harm to healthy.
According to theory of Chinese medical science, dispeling scar should with promoting blood circulation and breaking stagnation, softening the hard mass removing food stagnancy for the rule for the treatment of.Forefathers have also done a lot of research to traditional Chinese medical science dispeling scar.Patent documentation notification number CN101874863B discloses the invention of " external plaster of dispeling scar ", and it is made up of the raw material of following weight proportioning: Limonitum 10-150, Nodus Nelumbinis Rhizomatis 5-55, Rhizoma Pinelliae 15-200, egg albumen 50-250.This invention has blood stasis dispelling, the painful abdominal mass that disappears, eliminating stagnation, heat clearing away effect.Within about 5 weeks that cicatrix is light, can fully recover, cicatrix body can be almost recovered for darker 15 weeks.Its raw material cheaply and easily obtain, but the Rhizoma Pinelliae is poisonous plants, has certain toxic and side effects.
Patent documentation notification number CN100340275C discloses " liquid medicine for the treatment of cicatrix ", is soaked by Rhizoma Coptidis, Radix Scutellariae, Herba Cirsii, Radix Trichosanthis, the Radix Angelicae Dahuricae, Sanguis Draxonis, Radix Sanguisorbae, Rhizoma Paridis, Herba Artemisiae Anomalae, Bulbus Fritillariae Uninbracteatae, Radix Salviae Miltiorrhizae, Herba Menthae and forms for 2 to 4 months through the process of preparing Chinese medicine, rice wine.The cicatrix that this invention is applicable to burn and scald, operation wound and furuncle, innominate toxic swelling stays.But its Production Time is longer, pharmaceutical compositions is many, complicated, and cost compare is expensive.
Patent documentation notification number CN1931241B discloses " Chinese medicine reductant liquid for the treatment of cicatrix and preparation method thereof ", it is made up of the raw material of following weight proportioning: vinegar 85 parts, Mel 0.4 part, Radix Panacis Quinquefolii 2 parts, Rhizoma Chuanxiong 1.5 parts, Radix Saposhnikoviae 0.75 part, 1.5 parts, Flos Carthami, powder Radix Stephaniae Tetrandrae 2.75 parts, Radix Notoginseng 2 parts, Rhizoma Drynariae 0.5 part, Cortex Acanthopancis 0.6 part, Squama Manis 3 parts.Preparation method is that each raw material of Chinese medicine after pulverizing is put into vinegar and soaked 12-14 days, gets supernatant and filters, leave standstill and on little fire, decoct 4-5 days after 48 hours, adding Mel Homogeneous phase mixing, carrying out liquid subpackage, finished product.
From the above, some pharmaceutical compositions is many, complicated, and cost compare is expensive, increases financial burden to patient, therefore, needs the advantage playing Chinese medicine, for different symptoms, finds the Chinese patent medicine being more suitable for dispeling scar more.
Summary of the invention
Chinese medicine formula for prior art dispeling scar is complicated, cost is high, take effect the problem such as slow, the invention provides a kind of scar medicinal liquid changing skin and preparation method thereof of dispelling that a kind of toxic and side effects is little, evident in efficacy, cost is low, safe and reliable, the present invention also provides a kind of edible white vinegar to change the application of skin medicinal liquid as scar of dispelling.
For solving the problems of the technologies described above, technical scheme provided by the invention is: a kind of edible white vinegar changes the application of skin medicinal liquid as scar of dispelling.Scar of dispelling changes skin medicinal liquid, and the preparation of raw material formed by following weight percent forms: salicylic acid 8%-12%, Rhizoma Alpiniae Officinarum 18%-22%, edible white vinegar 68%-72%.
Further: to change in skin medicinal liquid in above-mentioned scar of dispelling, preferably, it is that the preparation of raw material formed by following weight percent forms: salicylic acid 10%, Rhizoma Alpiniae Officinarum 20%, edible white vinegar 70%.
Present invention also offers the preparation method that above-mentioned scar of dispelling changes skin medicinal liquid, comprise the following steps:
A, to smash: select Rhizoma Alpiniae Officinarum in proportion, be broken into particulate;
B, immersion: take salicylic acid in proportion, then be put into together with the Rhizoma Alpiniae Officinarum of steps A in the edible white vinegar that takes in proportion and soak 28 ~ 32 days, remove slag after filtration afterwards and can obtain medicinal liquid, then medicinal liquid is reduced to 88%-92% finished product medicinal liquid.
Using method of the present invention: spread upon affected part, medication 2-5 minute has pain, and namely medicine plays a role, and coating one time 5 minutes cicatrixes will be withered and be scabbed, and 7 to 10 days cicatrix meeting Automatic-fallings, skin just can recover as before.Due to medicinal liquid of the present invention, to be scabbed in the affected part of patient very fast, and in practical application, we also make this medicinal liquid be " 123 dispel scar change the medicinal liquid of skin ".
The edible white vinegar of medicine of the present invention is warm in nature, sour in the mouth, bitter in the mouth, returns liver, stomach warp.Have dissipating blood stasis, hemostasis, removing toxic substances, effect of parasite killing, and low price, be easy to get.The present invention only chooses the simple and raw material of formula and easily obtains, and preparation method is easier than prior art to be realized, and with low cost, patient easily accepts.In actual use, within 7 to 10 days, cicatrix gets final product Automatic-falling, instant effect, and effect is good.Therefore medicine of the present invention for scald, fire burn, scratch, explosive injury, get injured by a fall, function that old cicatrix that wound of performing the operation, motor exhaust are left over all has dispeling scar, instant effect, cure rate is high, has no side effect, and safety is good.
Detailed description of the invention
Purport of the present invention is the edible white vinegar selecting easily to obtain, and changes the application of skin medical fluid as scar of dispelling.Following embodiment illustrates to further illustrate the present invention, therefore, should not form limitation of the scope of the invention.
Embodiment 1
One scar of dispelling changes skin medicinal liquid, and the preparation of raw material formed by following weight percent forms: salicylic acid 8, Rhizoma Alpiniae Officinarum 22%, edible white vinegar 70%, and its preparation method comprises the following steps:
A, to smash: select Rhizoma Alpiniae Officinarum in proportion, be broken into particulate;
B, immersion: take salicylic acid in proportion, then be put into together with the Rhizoma Alpiniae Officinarum of steps A in the edible white vinegar that takes in proportion and soak 30 days, remove slag after filtration afterwards and can obtain medicinal liquid, then medicinal liquid is reduced to 90 finished product medicinal liquid.
Embodiment 2
One scar of dispelling changes skin medicinal liquid, and the preparation of raw material formed by following weight percent forms: salicylic acid 10, Rhizoma Alpiniae Officinarum 20%, edible white vinegar 70%, and its preparation method comprises the following steps:
A, to smash: select Rhizoma Alpiniae Officinarum in proportion, be broken into particulate;
B, immersion: take salicylic acid in proportion, then be put into together with the Rhizoma Alpiniae Officinarum of steps A in the edible white vinegar that takes in proportion and soak 31 days, remove slag after filtration afterwards and can obtain medicinal liquid, then medicinal liquid is reduced to 90 finished product medicinal liquid.
Embodiment 3
One scar of dispelling changes skin medicinal liquid, and the preparation of raw material formed by following weight percent forms: salicylic acid 12, Rhizoma Alpiniae Officinarum 18%, edible white vinegar 70%, and its preparation method comprises the following steps:
A, to smash: select Rhizoma Alpiniae Officinarum in proportion, be broken into particulate;
B, immersion: take salicylic acid in proportion, then be put into together with the Rhizoma Alpiniae Officinarum of steps A in the edible white vinegar that takes in proportion and soak 31 days, remove slag after filtration afterwards and can obtain medicinal liquid, then medicinal liquid is reduced to 90% finished product medicinal liquid.
Concentrated in above-described embodiment 1-3 refers to the method for concentration that this area is conventional, gets rid of moisture content, makes concentration of liquid medicine to the numerical value of setting.
Use procedure of the present invention: scar of dispelling is changed skin and changed skin medicinal liquid and be coated on cicatrix about 2 minutes and have and keenly feel.Patient generally uses scar of dispelling of the present invention to change skin and changes that skin medicinal liquid 2-3 days cicatrixes are just automatically withered to scab, and cicatrix light about 7 days cicatrixes can Automatic-falling, and after darker 10 days, cicatrix can Automatic-falling for cicatrix body, and skin just can recover as before.
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples include animal experiment and the clinical observation on the therapeutic effect test of medicine of the present invention.
One, the animal experiment of medicine
1. the present invention is to irritation test
Getting 3 body weight is the male rabbit of 2kg-3kg, tests first 24 hours, and remove the hair of back part of animal spinal column both sides by hair clipper for children, removal scope is 3cm × 3cm.Get tested material 0.5ml, smear the finished product medicinal liquid of above-described embodiment 1-3 in batches on the skin of unhairing of animal side, in contrast, application area is 2.5cm × 2.5cm to opposite side; Smear every day once, smear 10 days continuously.Smear cropping at every turn, remove residual tested material.Observed result after 1 hour, all animals of result 10 days smear in process, there is not erythema and edema phenomenon in tested skin.The present invention is to rabbit repeatedly irritation test result:
Animal subject repeatedly skin wound repair animal integral mean value average every day every is " 0 ".With reference to table 1 skin wound repair standards of grading scoring in " cosmetics health specification " (version in 2002) " skin irritation, corrosion test ", this sample is to animal skin nonirritant.
2. antiinflammatory action test of the present invention
Get the Male Wistar Rats of 16 body weight 170-200g, be divided into experimental group and matched group two groups.The each Mus back cropping of test proxima luce (prox. luc), area is 3cm × 3cm.Next day, in ether Qian Maxia sterile working, in the agar solution of dorsal midline subcutaneous injection 2%, point is sold experimental group wholesale and smears embodiment of the present invention 1-3 medicine, every day twice, continuous 10 days, within the 11st day, dissect animal, separate granuloma agar embryo, calculate weight in wet base by 100g body weight.The difference comparing two groups through statistical procedures finds, the granulomatous weight saving of agar of experimental group, illustrates that medicine of the present invention has the trend suppressing animal chronic nonspecific inflammation.
3. function of promoting blood circulation to disperse blood clots test of the present invention
Get the Male Wistar Rats of 16 170-200g, be divided into experimental group and matched group.Experimental group adopts the embodiment of the present invention 2 medicine, and matched group adopts glycerol.Test first 2 days, with 8% barium sulfide solution, auricle dorsal part hair on the right side of tested Mus is sloughed.Test was smeared by reagent 2 times by drafting dosage the morning on the same day, and midfeather 4 hours, after coating, half an hour carries out microcirculation detection.During detection with 0.3% Nembutal sodium solution 0.15ml/10g to Mus through intraperitoneal anesthesia.Supine is fixed on Mus plate, under the auricle of right side, places coverslip, and at its periphery dropstone wax oil, make auricle easily and slide be affixed, in horizontal level.Select Mus auricle line lateral border blood capillary, with the arteriole of caliber 6-8um and vein for the object of observation, observe the change of erythrocyte fluidised form and flow velocity in number that blood vessel opens a business, arteriole, the diameter change of venule and blood capillary respectively.More than observe and be use microscopic examination.Result experimental group blood capillary the first transaction of a day's business number is many compared with matched group, and microvascular diameter is larger than matched group, and blood vessel fluidised form and flow velocity comparatively matched group are fast, so medicine of the present invention has significant function of promoting blood circulation to disperse blood clots.
Two, clinical observation on the therapeutic effect test
1, physical data
Patient 110 example, male 48 example, women 62 example, the age, the course of disease was the shortest 2 months at 15 ~ 58 years old, the longest 10 years.There is cicatrix 189 place in 110 routine patients, its septum reset 99 place, trunk 23 place, extremity 67 place altogether.
2. diagnostic criteria
(1) there is scald, fire burn, scratch, explosive injury, get injured by a fall, wound of performing the operation, motor exhaust medical history person;
(2) wound surface convalescent period or repair after occur skin horizontal direction vertical direction infiltrate propagation the hard tuberosity exceeding skin or speckle.
3. Therapeutic Method
Select the medicinal liquid of above-described embodiment 2, spread upon affected part, twice on the one.Observe after 10 days.
4. criterion of therapeutical effect
Effective: cicatrix is thinning, the obvious deliquescing of quality.
Effective: cicatrix is slightly thinning, but gargalesthesia disappears, and pigment shoals.
Invalid: after treatment, symptom variation is little.
5. treat knot to look into
According to clinical efficacy standard, draw to draw a conclusion:
As can be seen from the above table, in above-mentioned treatment, treat after 7 ~ 15 days, this group 110 example, effective 56 examples, obvious effective rate 50.91%; Effective 47 examples, effective percentage 42.73%; Invalid 8 examples, inefficiency 6.36%; Total effective rate reaches 93.64%; Medicine instant effect of the present invention is described, cure rate is high, has no side effect, and safety is good.
6. model case:
Case 1: Chen, female, 30 years old
Medical history: patient on June 1st, 2010 because of caesarean operation after, lower abdomen leaves a cicatrix.
Analyze: because of Post operation blood stasis due to qi deficiency because of, make lower abdomen operative site leave a cicatrix, cicatrix body is lighter.
Treatment: eliminating stasis and resolving masses.
By being coated with the medicament 2 days of above-described embodiment 1, cicatrix is withered to scab, and about 7 days cicatrix Automatic-fallings, cure.
Case 2: Lee, female, 25 years old
Medical history: suffer from class and scalded women's head-ornaments, chest and back 12% in December, 2011 by radiator, scar after treatment.
Analyze: cause Accumulation of Dampness Heat and Blood Stasis owing to scalding.
Treatment: the medicament of painting above-described embodiment 32 days, cicatrix is withered to scab, and within about 10 days, cicatrix Automatic-falling disappears and fully recovers.
It should be noted that, these are only preferred embodiment of the present invention, do not departing under concept thereof of the present invention, any minor variations do the present invention and equivalent replacement, all belong to protection scope of the present invention.
Claims (3)
1. scar of dispelling changes a skin medicinal liquid, it is characterized in that the preparation of raw material formed by following weight percent forms: salicylic acid 8%-12%, Rhizoma Alpiniae Officinarum 18%-22%, edible white vinegar 68%-72%.
2. scar of dispelling according to claim 1 changes skin medicinal liquid, it is characterized in that the preparation of raw material formed by following weight percent forms: salicylic acid 10%, Rhizoma Alpiniae Officinarum 20%, edible white vinegar 70%.
3. prepare the method that scar of dispelling as claimed in claim 1 or 2 changes skin medicinal liquid, comprise the following steps:
A, to smash: select Rhizoma Alpiniae Officinarum in proportion, be broken into particulate;
B, immersion: take salicylic acid in proportion, then be put into together with the Rhizoma Alpiniae Officinarum of steps A in the edible white vinegar that takes in proportion and soak 28 ~ 32 days, remove slag after filtration afterwards and can obtain medicinal liquid, then medicinal liquid is reduced to 88%-92%, finished product medicinal liquid.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310438275.9A CN103463542B (en) | 2013-09-24 | 2013-09-24 | Application of edible vinegar as liquor for removing scars and changing skin, liquor for removing scars and changing skin and preparation method of liquor |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310438275.9A CN103463542B (en) | 2013-09-24 | 2013-09-24 | Application of edible vinegar as liquor for removing scars and changing skin, liquor for removing scars and changing skin and preparation method of liquor |
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| Publication Number | Publication Date |
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| CN103463542A CN103463542A (en) | 2013-12-25 |
| CN103463542B true CN103463542B (en) | 2015-04-15 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1377638A (en) * | 2002-04-18 | 2002-11-06 | 孙凤杰 | Foot tendering cream and preparation method thereof |
| CN1634389A (en) * | 2004-01-06 | 2005-07-06 | 吕德阗 | Scars reconditioning lotion containing linseed, hemp fimble seed and Java brucea fruit and preparing method thereof |
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- 2013-09-24 CN CN201310438275.9A patent/CN103463542B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1377638A (en) * | 2002-04-18 | 2002-11-06 | 孙凤杰 | Foot tendering cream and preparation method thereof |
| CN1634389A (en) * | 2004-01-06 | 2005-07-06 | 吕德阗 | Scars reconditioning lotion containing linseed, hemp fimble seed and Java brucea fruit and preparing method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 中兽医治疗烧伤;陈正迪等;《中兽医学杂志》;20090215(第01期);17 * |
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