CN103463398B - Traditional Chinese medicine composition, plaster and using method of plaster - Google Patents
Traditional Chinese medicine composition, plaster and using method of plaster Download PDFInfo
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- CN103463398B CN103463398B CN201310420370.6A CN201310420370A CN103463398B CN 103463398 B CN103463398 B CN 103463398B CN 201310420370 A CN201310420370 A CN 201310420370A CN 103463398 B CN103463398 B CN 103463398B
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Abstract
The invention provides a traditional Chinese medicine composition, a plaster and a using method of the plaster, wherein the traditional Chinese medicine composition is prepared from the following effective components in parts by weight: 17-19 parts of astragalus, 5-7 parts of asarum, 8-10 parts of radix saposhnikoviae, 8-10 parts of cortex mori, 8-10 parts of fritillaria pallidiflora schrenk, 8-10 parts of bitter apricot seeds and 8-10 parts of herba ephedrae. The traditional Chinese medicine composition provided by the invention is in a form of the plaster for external application to realize transdermal drug delivery; a heating device is additionally provided to promote the absorption of a drug and achieve the effects of promoting blood circulation to remove meridian obstruction and strengthening the drug effect; the traditional Chinese medicine composition is safe, free of toxic or side effect, simple and convenient in operation, free of operation by professional staff and good in compliance of patients.
Description
Technical field
The present invention relates to field of medicaments, in particular to the using method of Chinese medicine composition and application plaster and application plaster.
Background technology
Chronic obstructive pulmonary disease (chronic obstructive pulmonary disease; COPD) be can prevent and treatable common disease; it is characterized in that the flow limitation of sustainable existence and the development in Progressive symmetric erythrokeratodermia, with the increase to deleterious particle or induced gas chronic inflammatory reaction of air flue and lung.The COPD course of disease can be divided into Acute Exacerbation Period and stable phase.Therapeutic purposes are mitigation symptoms mainly, stops PD.The state of an illness of patient is in stable phase mostly at present, and the treatment patient of stable phase can by keeping good living habit, and ancillary drug treatment simultaneously reaches the object of mitigate the disease.
Problems existing is; current must have the patient of secondary symptom over the course for the treatment of; often can occur that possessiveness is more weak, life is disorderly, the unsound situation of living habit; so usually need drug administration to carry out emergent control; but the duration of efficacy of the medicine of the most auxiliary treatment used at present is short, more weak for alleviating of patients symptomatic.
Summary of the invention
The object of the present invention is to provide Chinese medicine composition, to solve the above problems.
Another object of the present invention is to provide the application plaster and using method be made up of this Chinese medicine composition.
The Chinese medicine composition provided in an embodiment of the present invention, by following effective ingredient by weight component be prepared from:
Radix Astragali 17-19 part, Herba Asari 5-7 part, Radix Saposhnikoviae 8-10 part, Cortex Mori 8-10 part, Bulbus Fritillariae Pallidiflorae 8-10 part, Semen Armeniacae Amarum 8-10 part, Herba ephedrae 8-10 part.
Additionally provide application plaster in an embodiment of the present invention, comprising: electro-heat equipment and medicated bag;
Described medicated bag is the packaging bag of breathability, built with the Radix Astragali of above-mentioned components by weight percent, and Herba Asari, Radix Saposhnikoviae, Cortex Mori, Bulbus Fritillariae Pallidiflorae, Semen Armeniacae Amarum, the mixed-powder of Herba ephedrae;
Described medicated bag is arranged on described electro-heat equipment.
Electro-heat equipment wherein can commercially availablely obtain.
Additionally provide the using method of application plaster in an embodiment of the present invention, comprise the following steps:
Medicated bag is arranged on electro-heat equipment;
Medicated bag is attached on the acupuncture point of user away from the side of described electro-heat equipment;
Electro-heat equipment heats.
Chinese medicine composition provided by the invention combines clinical experience prescription for many years by famous Traditional Chinese Medicine experts and forms, and through clinical application for many years checking, determined curative effect.Wherein Radix Astragali tonifying Qi and lifting yang, benefiting QI for strengthening the superficies; The pain relieving of Herba Asari expelling wind and cold; Radix Saposhnikoviae expelling pathogenic wind from the body surface, removing dampness to relieve pain; Cortex Mori eliminating pathogen from the lung for relieving asthma; Bulbus Fritillariae Pallidiflorae lung moistening, reduce phlegm, eliminating stagnation; Semen Armeniacae Amarum (parched) relieving cough and asthma, loosening bowel to relieve constipation; Herba ephedrae nourishing the lung to arrest cough, depressed lung-energy dispersing.Full side plays benefiting QI for strengthening the superficies, antiasthmatic-antitussive effect.For sweating, carry on the back the symptoms such as cool, susceptible, cough, asthma and have good curative effect, respiratory system disease patient CAT is marked, MMRC scoring and tcm symptom scoring improve significantly.
The application plaster property of medicine be made up of Chinese medicine composition provided by the invention is good, adopt external use plaster form, percutaneous dosing, additional heater, promotes drug absorption, to reach promoting blood circulation to remove obstruction in the collateral, and strengthen drug effect, safe without toxic side effect, simple to operation, do not need professional to operate, patient compliance is good.
Accompanying drawing explanation
Fig. 1 is the structural representation of application plaster provided by the invention;
The preparation method flow chart of the application plaster that Fig. 2 provides for the embodiment of the present invention 1;
The using method flow chart of the application plaster that Fig. 3 provides for the embodiment of the present invention 1;
1. tincture layer, 2. medicated bag, 3. electro-heat equipment.
Detailed description of the invention
Also by reference to the accompanying drawings the present invention is described in further detail below by specific embodiment.
Embodiment 1:
Chinese medicine composition, by following effective ingredient by weight component be prepared from:
Radix Astragali 17-19 part, Herba Asari 5-7 part, Radix Saposhnikoviae 8-10 part, Cortex Mori 8-10 part, Bulbus Fritillariae Pallidiflorae 8-10 part, Semen Armeniacae Amarum 8-10 part, Herba ephedrae 8-10 part.
Additionally provide application plaster in an embodiment of the present invention, as shown in Figure 1, comprising: electro-heat equipment 3 and medicated bag 2;
Described medicated bag 2 is the packaging bag of breathability, built with the Radix Astragali of described components by weight percent, and Herba Asari, Radix Saposhnikoviae, Cortex Mori, Bulbus Fritillariae Pallidiflorae, Semen Armeniacae Amarum, the mixed-powder of Herba ephedrae;
Described medicated bag 2 is arranged on described electro-heat equipment 3.
Electro-heat equipment 3 wherein can commercially availablely obtain.
Additionally provide the using method of application plaster as shown in Figure 2 in an embodiment of the present invention, comprise the following steps:
Medicated bag 2 is arranged on electro-heat equipment 3 by 101.;
Medicated bag 2 is attached on the acupuncture point of user away from the side of described electro-heat equipment 3 by 102.;
103. electro-heat equipments 3 heat.
Chinese medicine composition provided by the invention combines clinical experience prescription for many years by famous Traditional Chinese Medicine experts and forms, and through clinical application for many years checking, determined curative effect.Wherein Radix Astragali tonifying Qi and lifting yang, benefiting QI for strengthening the superficies; The pain relieving of Herba Asari expelling wind and cold; Radix Saposhnikoviae expelling pathogenic wind from the body surface, removing dampness to relieve pain; Cortex Mori eliminating pathogen from the lung for relieving asthma; Bulbus Fritillariae Pallidiflorae lung moistening, reduce phlegm, eliminating stagnation; Semen Armeniacae Amarum (parched) relieving cough and asthma, loosening bowel to relieve constipation; Herba ephedrae nourishing the lung to arrest cough, depressed lung-energy dispersing.Full side plays benefiting QI for strengthening the superficies, antiasthmatic-antitussive effect.For sweating, carry on the back the symptoms such as cool, susceptible, cough, asthma and have good curative effect, respiratory system disease patient CAT is marked, MMRC scoring and tcm symptom scoring improve significantly.
The application plaster property of medicine be made up of Chinese medicine composition provided by the invention is good, adopt external use plaster form, percutaneous dosing, additional heater, promotes drug absorption, to reach promoting blood circulation to remove obstruction in the collateral, and strengthen drug effect, safe without toxic side effect, simple to operation, do not need professional to operate, patient compliance is good.
Embodiment 2:
Chinese medicine composition, by following effective ingredient by weight component be prepared from:
The Radix Astragali 18 parts, Herba Asari 6 parts, Radix Saposhnikoviae 9 parts, Cortex Mori 9 parts, Bulbus Fritillariae Pallidiflorae 9 parts, Semen Armeniacae Amarum 9 parts, Herba ephedrae 9 parts.
Additionally provide application plaster in an embodiment of the present invention, comprising: electro-heat equipment 3 and medicated bag 2;
Described medicated bag 2 is the Radix Astragali of packaging bag built with described components by weight percent of breathability, Herba Asari, Radix Saposhnikoviae, Cortex Mori, Bulbus Fritillariae Pallidiflorae, Semen Armeniacae Amarum, the mixed-powder of Herba ephedrae;
Described medicated bag 2 is arranged on described electro-heat equipment 3.
Electro-heat equipment 3 wherein can commercially availablely obtain.
Wherein packaging bag can be nonwoven fabrics package bag.
Come out better for the ease of drug effect, mixed-powder can be pulverized, preferably, the particle diameter after mixed-powder pulverizing is 80-100 order.
In order to improve the stable connection of medicated bag 2 and electro-heat equipment 3, tack coat can be set on electro-heat equipment 3, be bondd by medicated bag 2 described in this tack coat and described electro-heat equipment 3.
The speed that sheds of drug effect during in order to promote just to bring into use application plaster, tincture layer 1 can be applied on medicated bag 2, particularly, this tincture layer 1 is by the Radix Astragali of constant weight component, Herba Asari, Radix Saposhnikoviae, Cortex Mori, Bulbus Fritillariae Pallidiflorae, Semen Armeniacae Amarum, add in the mixed-powder 2000g of Herba ephedrae 10kg concentration be 75% ethanol mixing seal the tincture that is brewed to and be coated on described medicated bag 2 and formed, this tincture layer 1 is coated in the side of described medicated bag 2 away from described electro-heat equipment 3, by promoting that human body is to the absorption of medicine by this tincture layer 1, additional heater, promoting blood circulation to remove obstruction in the collateral can be reached, and strengthen drug effect.
The using method of application plaster as shown in Figure 3, comprises the following steps:
201. at the side coating tincture formation tincture layer 1 of medicated bag 2 away from electro-heat equipment 3,
The opposite side of medicated bag 2 is bonded on electro-heat equipment 3 by 202.;
Side medicated bag 2 being coated with tincture is attached on the acupuncture point of user by 203.;
204. electro-heat equipments 3 heat.
The preparation method of wherein said tincture is specially by the Radix Astragali of aforementioned weight component, Herba Asari, Radix Saposhnikoviae, Cortex Mori, Bulbus Fritillariae Pallidiflorae, Semen Armeniacae Amarum, add in the mixed-powder 2000g of Herba ephedrae 10kg concentration be 75% ethanol mixing sealing brewedly to make, get its supernatant after 3 days and be coated in the surface of medicated bag 2 and tincture layer 1 is sticked on the acupuncture point of patient.Sealing is noted, in order to avoid ethanol volatilization in brew process.
Chinese medicine composition provided by the invention combines clinical experience prescription for many years by famous Traditional Chinese Medicine experts and forms, and through clinical application for many years checking, determined curative effect.Wherein Radix Astragali tonifying Qi and lifting yang, benefiting QI for strengthening the superficies; The pain relieving of Herba Asari expelling wind and cold; Radix Saposhnikoviae expelling pathogenic wind from the body surface, removing dampness to relieve pain; Cortex Mori eliminating pathogen from the lung for relieving asthma; Bulbus Fritillariae Pallidiflorae lung moistening, reduce phlegm, eliminating stagnation; Semen Armeniacae Amarum (parched) relieving cough and asthma, loosening bowel to relieve constipation; Herba ephedrae nourishing the lung to arrest cough, depressed lung-energy dispersing.Full side plays benefiting QI for strengthening the superficies, antiasthmatic-antitussive effect.For sweating, carry on the back the symptoms such as cool, susceptible, cough, asthma and have good curative effect, respiratory system disease patient CAT is marked, MMRC scoring and tcm symptom scoring improve significantly.
The application plaster property of medicine be made up of Chinese medicine composition provided by the invention is good, adopt external use plaster form, percutaneous dosing, additional heater, promotes drug absorption, to reach promoting blood circulation to remove obstruction in the collateral, and strengthen drug effect, safe without toxic side effect, simple to operation, do not need professional to operate, patient compliance is good.
Tincture is applied on medicated bag 2 when using by heater, after making the mixed-powder in medicated bag 2 fully absorb tincture, medicated bag 2 is affixed on heater with on the face of viscose glue, the area of medicated bag 2 is less than the area of heater, then is affixed on by whole heater on the skin at corresponding acupuncture point again.There is medicine to intercept between electro-heat equipment 3 and skin, skin low temperature can not be produced and scald.By the heating functioin adding hot charging, medicine by infiltrating skin after tincture solution absorption, then can promote that skin is to the absorption of medicine, strengthens therapeutic effect.
Clinical trial proves:
Clinically include 30 routine stable phase chronic obstructive pulmonary disease patients patients in.
Applying method: in the morning 11 time, with spreading on two fei shu, Pishu acupuncture point outside application plaster of relievining asthma, keeping 6h, one week 2 times, continuing 6 weeks.
This test amounts to into group patients with chronic obstructive pulmonary diseases 30 example, compares discovery before treatment, after treatment:
1. relievining asthma applies ointment or plaster significantly can improve patient B ODE index (P<0.05),
BODE index score method:
0 point: FEV1% >=65%, 6 minutes walking >350 rice, breathes limited scoring 0 ~ 1 point, Body Mass Index >21;
1 point: FEV1% is walking in 50% ~ 64%, 6 minutes 250 meters ~ 349 meters, breathes limited scoring 2 points, Body Mass Index≤21;
2 points: FEV1% is walking in 36% ~ 49%, 6 minutes 150 meters ~ 249 meters, breathes limited scoring 3 points;
3 points: FEV1% is≤35%, 6 minutes walking≤149 meter, breathes limited scoring 4 points.
Each component value is added and obtains BODE index score.
2. relievining asthma applies ointment or plaster significantly can improve the every symptom of patient: cough, expectoration, pant, breathe hard, abdominal distention, spontaneous perspiration, the back of the body are cool, easy catching a cold.
As can be seen from above test, use Chinese medicine composition provided by the invention and the application plaster that uses this Chinese medicine composition to make evident in efficacy.
Result display is by treatment, apply ointment or plaster add thermotherapy group BODE index by 4.27 before treating be down to treat after 2.93, statistical significance is interpreted as on average adding 23.67m before 6 minutes walking distances are comparatively treated, and CAT marks and comparatively treats front decreased average 3.46, and front decreased average 5.46 is comparatively treated in tcm symptom scoring.
Wherein to cough, expectoration, pant, breathe hard, symptom that abdominal distention, spontaneous perspiration, the back of the body are cool improves the most remarkable.
The curative effect that the traditional Chinese medical science sticks superposition thermotherapy is more embodied in the improvement aspect of patient's subjective symptom, and namely to improve subjective symptom, application therapy is easy and simple to handle in clinical, and patient is easy to accept, and compliance is good, and safety is high.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (6)
1. application plaster, is characterized in that, comprising: electro-heat equipment and medicated bag;
Described medicated bag is the packaging bag of breathability, built with the Radix Astragali, and Herba Asari, Radix Saposhnikoviae, Cortex Mori, Bulbus Fritillariae Pallidiflorae, Semen Armeniacae Amarum, the mixed-powder of Herba ephedrae; The component proportion of described mixed-powder is: Radix Astragali 17-19 part, Herba Asari 5-7 part, Radix Saposhnikoviae 8-10 part, Cortex Mori 8-10 part, Bulbus Fritillariae Pallidiflorae 8-10 part, Semen Armeniacae Amarum 8-10 part, Herba ephedrae 8-10 part;
Described medicated bag is arranged on described electro-heat equipment.
2. application plaster according to claim 1, is characterized in that,
Described packaging bag is nonwoven fabrics package bag.
3. application plaster according to claim 1, is characterized in that,
The particle diameter of described mixed-powder is 80-100 order.
4. application plaster according to claim 1, is characterized in that,
Described electro-heat equipment is provided with tack coat, by medicated bag described in described tack coat and described electro-heat equipment bonding.
5. application plaster according to claim 1, it is characterized in that, also comprise by the Radix Astragali of the components by weight percent described in claim 1 or 2, Herba Asari, Radix Saposhnikoviae, Cortex Mori, Bulbus Fritillariae Pallidiflorae, Semen Armeniacae Amarum, add in the mixed-powder 2000g of Herba ephedrae 10kg concentration be 75% ethanol mixing seal the tincture that is brewed to and be coated in the tincture layer that described medicated bag is formed;
Described tincture layer is coated in the side of described medicated bag away from described electro-heat equipment;
The preparation method of described tincture is:
By the Radix Astragali of the components by weight percent described in claim 1 or 2, Herba Asari, Radix Saposhnikoviae, Cortex Mori, Bulbus Fritillariae Pallidiflorae, Semen Armeniacae Amarum, add in the mixed-powder 2000g of Herba ephedrae 10kg concentration be 75% ethanol mixing sealing brewed, get its supernatant after 3 days.
6. application plaster according to claim 1, is characterized in that, the component proportion of described mixed-powder is: the Radix Astragali 18 parts, Herba Asari 6 parts, Radix Saposhnikoviae 9 parts, Cortex Mori 9 parts, Bulbus Fritillariae Pallidiflorae 9 parts, Semen Armeniacae Amarum 9 parts, Herba ephedrae 9 parts.
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| CN201310420370.6A CN103463398B (en) | 2013-09-13 | 2013-09-13 | Traditional Chinese medicine composition, plaster and using method of plaster |
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| CN201310420370.6A CN103463398B (en) | 2013-09-13 | 2013-09-13 | Traditional Chinese medicine composition, plaster and using method of plaster |
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| CN103463398B true CN103463398B (en) | 2015-01-21 |
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| CN1314387C (en) * | 2003-05-21 | 2007-05-09 | 西安碑林药业股份有限公司 | Children cough and asthma treating Chinese traditional medicine and its preparation |
| CN101254296B (en) * | 2008-03-25 | 2011-06-22 | 深圳力瑞医药科技有限公司 | Pharmaceutical combination with relieving cough, curing asthma and throat-moistening resolve phlegm effect and method of preparing the same |
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Inventor after: Li Fengsen Inventor after: Li Zheng Inventor after: Wang Xin Inventor after: Gao Zhen Inventor after: Jing Jing Inventor after: Xu Dan Inventor after: Wang Jing Inventor before: Li Fengsen |
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