CN103463398A - Traditional Chinese medicine composition, plaster and using method of plaster - Google Patents
Traditional Chinese medicine composition, plaster and using method of plaster Download PDFInfo
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- CN103463398A CN103463398A CN2013104203706A CN201310420370A CN103463398A CN 103463398 A CN103463398 A CN 103463398A CN 2013104203706 A CN2013104203706 A CN 2013104203706A CN 201310420370 A CN201310420370 A CN 201310420370A CN 103463398 A CN103463398 A CN 103463398A
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Abstract
The invention provides a traditional Chinese medicine composition, a plaster and a using method of the plaster, wherein the traditional Chinese medicine composition is prepared from the following effective components in parts by weight: 17-19 parts of astragalus, 5-7 parts of asarum, 8-10 parts of radix saposhnikoviae, 8-10 parts of cortex mori, 8-10 parts of fritillaria pallidiflora schrenk, 8-10 parts of bitter apricot seeds and 8-10 parts of herba ephedrae. The traditional Chinese medicine composition provided by the invention is in a form of the plaster for external application to realize transdermal drug delivery; a heating device is additionally provided to promote the absorption of a drug and achieve the effects of promoting blood circulation to remove meridian obstruction and strengthening the drug effect; the traditional Chinese medicine composition is safe, free of toxic or side effect, simple and convenient in operation, free of operation by professional staff and good in compliance of patients.
Description
Technical field
The present invention relates to field of medicaments, in particular to the using method of Chinese medicine composition and application plaster and application plaster.
Background technology
Chronic obstructive pulmonary disease (chronic obstructive pulmonary disease; COPD) be can prevent and treatable common disease; it is characterized in that the flow limitation of sustainable existence and be carrying out sexual development the increase with air flue and lung to deleterious particle or induced gas chronic inflammatory reaction.The COPD course of disease can be divided into Acute Exacerbation Period and stable phase.Therapeutic purposes are mainly mitigation symptoms, stop PD.Patient's the state of an illness is in stable phase mostly at present, and the treatment patient of stable phase can be by keeping good living habit, and ancillary drug treats to reach the purpose of mitigate the disease simultaneously.
The problem existed is; current must have the patient of inferior symptom in therapeutic process; often can occur that possessiveness is weak, life is disorderly, the unsound situation of living habit; so usually need drug administration to carry out emergent control; but the duration of efficacy of the medicine of most auxiliary treatment of using at present is short, more weak for alleviating of patient's symptom.
Summary of the invention
The object of the present invention is to provide Chinese medicine composition, to solve the above problems.
Another object of the present invention is to provide application plaster and the using method of being made by this Chinese medicine composition.
The Chinese medicine composition provided in an embodiment of the present invention, by following effective ingredient by weight component be prepared from:
Radix Astragali 17-19 part, Herba Asari 5-7 part, Radix Saposhnikoviae 8-10 part, Cortex Mori 8-10 part, Bulbus Fritillariae Pallidiflorae 8-10 part, Semen Armeniacae Amarum 8-10 part, sweet Herba Ephedrae 8-10 part.
Application plaster also is provided in an embodiment of the present invention, has comprised: electro-heat equipment and medicated bag;
The packaging bag that described medicated bag is breathability, inside be equipped with the Radix Astragali of above-mentioned components by weight percent, Herba Asari, Radix Saposhnikoviae, Cortex Mori, Bulbus Fritillariae Pallidiflorae, Semen Armeniacae Amarum, the mixed-powder of sweet Herba Ephedrae;
Described medicated bag is arranged on described electro-heat equipment.
Electro-heat equipment wherein can commercially availablely obtain.
The using method of application plaster also is provided in an embodiment of the present invention, has comprised the following steps:
Medicated bag is arranged on electro-heat equipment;
A side by medicated bag away from described electro-heat equipment is attached on the acupuncture point of user;
The electro-heat equipment heating.
Chinese medicine composition provided by the invention is formed in conjunction with clinical experience prescription for many years by famous Traditional Chinese Medicine experts, and through clinical application for many years checking, determined curative effect.Wherein Radix Astragali tonifying Qi and lifting yang, benefiting QI for strengthening the superficies; The pain relieving of Herba Asari expelling wind and cold; Radix Saposhnikoviae expelling pathogenic wind from the body surface, removing dampness to relieve pain; The Cortex Mori eliminating pathogen from the lung for relieving asthma; The Bulbus Fritillariae Pallidiflorae lung moistening, reduce phlegm, eliminating stagnation; Semen Armeniacae Amarum (parched) relieving cough and asthma, loosening bowel to relieve constipation; Honey Herba Ephedrae nourishing the lung to arrest cough, depressed lung-energy dispersing.Benefiting QI for strengthening the superficies, antiasthmatic-antitussive effect are played by full side.For sweating, carry on the back the symptoms such as cool, susceptible, cough, asthma curative effect preferably arranged, respiratory system disease patient CAT scoring, MMRC scoring and tcm symptom scoring are improved significantly.
The application plaster property of medicine of being made by Chinese medicine composition provided by the invention is good, adopt the external use plaster form, percutaneous dosing, additional heater, promote drug absorption, to reach promoting blood circulation to remove obstruction in the collateral, and the reinforcement drug effect, safe without toxic side effect, simple to operation, do not need the professional to operate, patient compliance is good.
The accompanying drawing explanation
The structural representation that Fig. 1 is application plaster provided by the invention;
The preparation method flow chart of the application plaster that Fig. 2 provides for the embodiment of the present invention 1;
The using method flow chart of the application plaster that Fig. 3 provides for the embodiment of the present invention 1;
1. tincture layer, 2. medicated bag, 3. electro-heat equipment.
The specific embodiment
Below by specific embodiment, also by reference to the accompanying drawings the present invention is described in further detail.
Embodiment 1:
Chinese medicine composition, by following effective ingredient by weight component be prepared from:
Radix Astragali 17-19 part, Herba Asari 5-7 part, Radix Saposhnikoviae 8-10 part, Cortex Mori 8-10 part, Bulbus Fritillariae Pallidiflorae 8-10 part, Semen Armeniacae Amarum 8-10 part, sweet Herba Ephedrae 8-10 part.
Application plaster also is provided in an embodiment of the present invention, as shown in Figure 1, has comprised: electro-heat equipment 3 and medicated bag 2;
The packaging bag that described medicated bag 2 is breathability, the in-built Radix Astragali that described components by weight percent is arranged, Herba Asari, Radix Saposhnikoviae, Cortex Mori, Bulbus Fritillariae Pallidiflorae, Semen Armeniacae Amarum, the mixed-powder of sweet Herba Ephedrae;
Described medicated bag 2 is arranged on described electro-heat equipment 3.
Electro-heat equipment 3 wherein can commercially availablely obtain.
The using method of application plaster as shown in Figure 2 also is provided in an embodiment of the present invention, has comprised the following steps:
101. medicated bag 2 is arranged on electro-heat equipment 3;
102. the side by medicated bag 2 away from described electro-heat equipment 3 is attached on the acupuncture point of user;
103. electro-heat equipment 3 heating.
Chinese medicine composition provided by the invention is formed in conjunction with clinical experience prescription for many years by famous Traditional Chinese Medicine experts, and through clinical application for many years checking, determined curative effect.Wherein Radix Astragali tonifying Qi and lifting yang, benefiting QI for strengthening the superficies; The pain relieving of Herba Asari expelling wind and cold; Radix Saposhnikoviae expelling pathogenic wind from the body surface, removing dampness to relieve pain; The Cortex Mori eliminating pathogen from the lung for relieving asthma; The Bulbus Fritillariae Pallidiflorae lung moistening, reduce phlegm, eliminating stagnation; Semen Armeniacae Amarum (parched) relieving cough and asthma, loosening bowel to relieve constipation; Honey Herba Ephedrae nourishing the lung to arrest cough, depressed lung-energy dispersing.Benefiting QI for strengthening the superficies, antiasthmatic-antitussive effect are played by full side.For sweating, carry on the back the symptoms such as cool, susceptible, cough, asthma curative effect preferably arranged, respiratory system disease patient CAT scoring, MMRC scoring and tcm symptom scoring are improved significantly.
The application plaster property of medicine of being made by Chinese medicine composition provided by the invention is good, adopt the external use plaster form, percutaneous dosing, additional heater, promote drug absorption, to reach promoting blood circulation to remove obstruction in the collateral, and the reinforcement drug effect, safe without toxic side effect, simple to operation, do not need the professional to operate, patient compliance is good.
Embodiment 2:
Chinese medicine composition, by following effective ingredient by weight component be prepared from:
18 parts of the Radixs Astragali, 6 parts of Herba Asaris, 9 parts of Radix Saposhnikoviaes, 9 parts of Cortex Mori, 9 parts of Bulbus Fritillariae Pallidifloraes, 9 parts of Semen Armeniacae Amarums, 9 parts, sweet Herba Ephedrae.
Application plaster also is provided in an embodiment of the present invention, has comprised: electro-heat equipment 3 and medicated bag 2;
Described medicated bag 2 is the in-built Radix Astragali that described components by weight percent is arranged of packaging bag of breathability, Herba Asari, Radix Saposhnikoviae, Cortex Mori, Bulbus Fritillariae Pallidiflorae, Semen Armeniacae Amarum, the mixed-powder of sweet Herba Ephedrae;
Described medicated bag 2 is arranged on described electro-heat equipment 3.
Electro-heat equipment 3 wherein can commercially availablely obtain.
Wherein packaging bag can be nonwoven fabrics package bag.
Come out better for the ease of drug effect, mixed-powder can be pulverized, preferably, the particle diameter after mixed-powder is pulverized is the 80-100 order.
In order to improve the stable connection of medicated bag 2 and electro-heat equipment 3, can on electro-heat equipment 3, tack coat be set, by the described medicated bag 2 of this tack coat and described electro-heat equipment 3 bondings.
The speed that sheds of drug effect in order to promote just to bring into use application plaster, can on medicated bag 2, apply tincture layer 1, particularly, this tincture layer 1 is the Radix Astragali by the constant weight component, Herba Asari, Radix Saposhnikoviae, Cortex Mori, Bulbus Fritillariae Pallidiflorae, Semen Armeniacae Amarum, in the mixed-powder 2000g of honey Herba Ephedrae, adding ethanol that 10kg concentration is 75% to mix tincture that sealing is brewed to is coated in and forms on described medicated bag 2, this tincture layer 1 is coated in the side of described medicated bag 2 away from described electro-heat equipment 3, by by this tincture layer 1, promoting the absorption of human body to medicine, additional heater, can reach promoting blood circulation to remove obstruction in the collateral, and reinforcement drug effect.
The using method of application plaster as shown in Figure 3 comprises the following steps:
201. the side coating tincture formation tincture layer 1 at medicated bag 2 away from electro-heat equipment 3,
202. the opposite side of medicated bag 2 is bonded on electro-heat equipment 3;
203. a side that is coated with tincture on medicated bag 2 is attached on the acupuncture point of user;
204. electro-heat equipment 3 heating.
The preparation method of wherein said tincture is specially the Radix Astragali by aforementioned components by weight percent, Herba Asari, Radix Saposhnikoviae, Cortex Mori, Bulbus Fritillariae Pallidiflorae, Semen Armeniacae Amarum, add the ethanol that 10kg concentration is 75% to mix brewed the making of sealing in the mixed-powder 2000g of sweet Herba Ephedrae, get its supernatant after 3 days and be coated in the surface of medicated bag 2 and tincture layer 1 sticked on patient's acupuncture point.Note sealing in brew process, in order to avoid the ethanol volatilization.
Chinese medicine composition provided by the invention is formed in conjunction with clinical experience prescription for many years by famous Traditional Chinese Medicine experts, and through clinical application for many years checking, determined curative effect.Wherein Radix Astragali tonifying Qi and lifting yang, benefiting QI for strengthening the superficies; The pain relieving of Herba Asari expelling wind and cold; Radix Saposhnikoviae expelling pathogenic wind from the body surface, removing dampness to relieve pain; The Cortex Mori eliminating pathogen from the lung for relieving asthma; The Bulbus Fritillariae Pallidiflorae lung moistening, reduce phlegm, eliminating stagnation; Semen Armeniacae Amarum (parched) relieving cough and asthma, loosening bowel to relieve constipation; Honey Herba Ephedrae nourishing the lung to arrest cough, depressed lung-energy dispersing.Benefiting QI for strengthening the superficies, antiasthmatic-antitussive effect are played by full side.For sweating, carry on the back the symptoms such as cool, susceptible, cough, asthma curative effect preferably arranged, respiratory system disease patient CAT scoring, MMRC scoring and tcm symptom scoring are improved significantly.
The application plaster property of medicine of being made by Chinese medicine composition provided by the invention is good, adopt the external use plaster form, percutaneous dosing, additional heater, promote drug absorption, to reach promoting blood circulation to remove obstruction in the collateral, and the reinforcement drug effect, safe without toxic side effect, simple to operation, do not need the professional to operate, patient compliance is good.
Heater is applied to tincture on medicated bag 2 while using, after making medicated bag 2 interior mixed-powders fully absorb tincture, medicated bag 2 is affixed on the face of heater with viscose glue, the area of medicated bag 2 is less than the area of heater, more whole heater is affixed on the skin at corresponding acupuncture point again.Between electro-heat equipment 3 and skin, there is medicine to intercept, can not produce skin low temperature and scald.Medicine can be by after the tincture solution absorption, infiltrating skin, then promote the absorption of skin to medicine by the heating functioin that adds hot charging, strengthens therapeutic effect.
Clinical trial proves:
Clinically include 30 routine stable phase chronic obstructive pulmonary disease patients patients in.
Applying method: at 11 o'clock in the morning, with the application plaster of relievining asthma, spread on two fei shus, Pishu acupuncture point outward, keep 6h, one week 2 times, continue 6 weeks.
This test amounts to into group patients with chronic obstructive pulmonary diseases 30 examples, relatively discovery before treatment, after treatment:
1. relievining asthma applies ointment or plaster can significantly improve patient B ODE index (P<0.05),
BODE index methods of marking:
0 minute: FEV1% >=65%, 6 minute walking > 350 meters, breathe limited scoring 0～1 minute, Body Mass Index > 21;
1 minute: FEV1% was 250 meters～349 meters of walkings in 50%～64%, 6 minutes, breathes limited scoring 2 minutes, Body Mass Index≤21;
2 minutes: FEV1% was 150 meters～249 meters of walkings in 36%～49%, 6 minutes, breathes limited scoring 3 minutes;
3 minutes: FEV1% was≤35%, 6 minutes walking≤149 meter, breathes limited scoring 4 minutes.
Each component value addition obtains BODE index score value.
2. relievining asthma applies ointment or plaster can significantly improve the every symptom of patient: cough, expectoration, pant, breathe hard, abdominal distention, spontaneous perspiration, the back of the body are cool, easy catching a cold.
By above test, can be found out, the application plaster that uses Chinese medicine composition provided by the invention and use this Chinese medicine composition to make is evident in efficacy.
Result shows by treatment, apply ointment or plaster add thermotherapy group BODE index by 4.27 before treating be down to treat after 2.93, statistical significance is interpreted as before 6 minutes walking distances are treated on average having increased 23.67m, CAT scoring treat before decreased average 3.46, the tcm symptom scoring treat before decreased average 5.46.
Wherein to cough, expectoration, pant, breathe hard, abdominal distention, spontaneous perspiration, doing well,improving that the back of the body is cool be the most remarkable.
The curative effect that the traditional Chinese medical science sticks the stack thermotherapy more is embodied in the aspect of improving of patient's subjective symptom, take and improves subjective symptom as main, and application therapy is easy and simple to handle in clinical, and the patient is easy to accept, and compliance is good, safe.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (10)
1. Chinese medicine composition, is characterized in that, by following effective ingredient by weight component be prepared from:
Radix Astragali 17-19 part, Herba Asari 5-7 part, Radix Saposhnikoviae 8-10 part, Cortex Mori 8-10 part, Bulbus Fritillariae Pallidiflorae 8-10 part, Semen Armeniacae Amarum 8-10 part, sweet Herba Ephedrae 8-10 part.
2. Chinese medicine composition according to claim 1, is characterized in that, by following effective ingredient by weight component be prepared from:
18 parts of the Radixs Astragali, 6 parts of Herba Asaris, 9 parts of Radix Saposhnikoviaes, 9 parts of Cortex Mori, 9 parts of Bulbus Fritillariae Pallidifloraes, 9 parts of Semen Armeniacae Amarums, 9 parts, sweet Herba Ephedrae.
3. application plaster, is characterized in that, comprising: electro-heat equipment and medicated bag;
The packaging bag that described medicated bag is breathability, the Radix Astragali of in-built the requirement 1 or 2 described components by weight percent of having the right, Herba Asari, Radix Saposhnikoviae, Cortex Mori, Bulbus Fritillariae Pallidiflorae, Semen Armeniacae Amarum, the mixed-powder of sweet Herba Ephedrae;
Described medicated bag is arranged on described electro-heat equipment.
4. application plaster according to claim 3, is characterized in that,
Described packaging bag is nonwoven fabrics package bag.
5. application plaster according to claim 3, is characterized in that,
The particle diameter of described mixed-powder is the 80-100 order.
6. application plaster according to claim 3, is characterized in that,
Described electro-heat equipment is provided with tack coat, by the described medicated bag of described tack coat and described electro-heat equipment bonding.
7. application plaster according to claim 3, it is characterized in that, also comprise the Radix Astragali by claim 1 or 2 described components by weight percent, Herba Asari, Radix Saposhnikoviae, Cortex Mori, Bulbus Fritillariae Pallidiflorae, Semen Armeniacae Amarum, add ethanol that 10kg concentration is 75% to mix the tincture that sealing is brewed to and be coated in the tincture layer formed on described medicated bag in the mixed-powder 2000g of sweet Herba Ephedrae;
Described tincture layer is coated in the side of described medicated bag away from described electro-heat equipment.
8. the using method of application plaster, is characterized in that, comprises the following steps:
Medicated bag is arranged on electro-heat equipment;
A side by medicated bag away from described electro-heat equipment is attached on the acupuncture point of user;
The electro-heat equipment heating.
9. the using method of application plaster according to claim 8, is characterized in that,
Described medicated bag is arranged on to the step on electro-heat equipment after, before the step on the described acupuncture point that medicated bag is attached to user away from a side of described electro-heat equipment, also comprise:
A side coating tincture at described medicated bag away from described electro-heat equipment.
10. the using method of application plaster according to claim 8, is characterized in that, the preparation method of described tincture is:
By the Radix Astragali of claim 1 or 2 described components by weight percent, Herba Asari, Radix Saposhnikoviae, Cortex Mori, Bulbus Fritillariae Pallidiflorae, Semen Armeniacae Amarum, add the ethanol mixing sealing that 10kg concentration is 75% brewed in the mixed-powder 2000g of sweet Herba Ephedrae, after 3 days, get its supernatant.
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| CN201310420370.6A CN103463398B (en) | 2013-09-13 | 2013-09-13 | Traditional Chinese medicine composition, plaster and using method of plaster |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110613790A (en) * | 2019-11-12 | 2019-12-27 | 广东食品药品职业学院 | Cough relieving plaster and preparation method thereof |
Citations (3)
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| CN1193535A (en) * | 1998-03-21 | 1998-09-23 | 朱殿文 | Capsule against cough |
| CN1544071A (en) * | 2003-05-21 | 2004-11-10 | 西安碑林药业股份有限公司 | Children cough and asthma treating Chinese traditional medicine and its preparation |
| CN101254296A (en) * | 2008-03-25 | 2008-09-03 | 深圳力瑞医药科技有限公司 | Pharmaceutical combination with relieving cough, curing asthma and throat-moistening resolve phlegm effect and method of preparing the same |
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2013
- 2013-09-13 CN CN201310420370.6A patent/CN103463398B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1193535A (en) * | 1998-03-21 | 1998-09-23 | 朱殿文 | Capsule against cough |
| CN1544071A (en) * | 2003-05-21 | 2004-11-10 | 西安碑林药业股份有限公司 | Children cough and asthma treating Chinese traditional medicine and its preparation |
| CN101254296A (en) * | 2008-03-25 | 2008-09-03 | 深圳力瑞医药科技有限公司 | Pharmaceutical combination with relieving cough, curing asthma and throat-moistening resolve phlegm effect and method of preparing the same |
Non-Patent Citations (2)
| Title |
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| 张伟等: "五种不同中药经典方剂影响各型慢性阻塞性肺疾病大鼠气道病理改变的特点", 《中国临床康复》, vol. 10, no. 47, 21 December 2006 (2006-12-21) * |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110613790A (en) * | 2019-11-12 | 2019-12-27 | 广东食品药品职业学院 | Cough relieving plaster and preparation method thereof |
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Inventor after: Li Fengsen Inventor after: Li Zheng Inventor after: Wang Xin Inventor after: Gao Zhen Inventor after: Jing Jing Inventor after: Xu Dan Inventor after: Wang Jing Inventor before: Li Fengsen |
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