CN103463313A - Traditional Chinese medicine for treating hemicrania and preparation method thereof - Google Patents
Traditional Chinese medicine for treating hemicrania and preparation method thereof Download PDFInfo
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- CN103463313A CN103463313A CN2013104135889A CN201310413588A CN103463313A CN 103463313 A CN103463313 A CN 103463313A CN 2013104135889 A CN2013104135889 A CN 2013104135889A CN 201310413588 A CN201310413588 A CN 201310413588A CN 103463313 A CN103463313 A CN 103463313A
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Abstract
The invention discloses a traditional Chinese medicine for treating hemicrania. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 10-15 parts of dried rhizome of rehmannia, 20-25 parts of angelica sinensis, 15-25 parts of peach kernel, 12-15 parts of flowers carthami, 15-20 parts of fructus aurantii, 20-25 parts of root of common peony, 15-20 parts of radix bupleuri, 25-30 parts of ligusticum wallichii, 15-20 parts of radix angelicae, 15-20 parts of chrysanthemum, 10-15 parts of notopterygium root, 20-25 parts of radices ligustici sinensis, 20-25 parts of fructus viticis, 10-15 parts of radices sileris, 18-20 parts of radix achyranthis bidentatae, 15-20 parts of platycodon grandiflorum and 10-15 parts of liquorice. By adopting the traditional Chinese medicine, the hemicrania, especially the hemicrania, headache, prosopalgia and neurasthenic syndrome caused by liver depression and qi stagnation, and obstruction of collaterals by blood stasis can be effectively treated; the traditional Chinese medicine is significant in curative effect, free of toxic and side effects, high in safety, convenient to take and low in price.
Description
Technical field
The present invention relates to a kind of migrainous Chinese medicine and preparation method thereof for the treatment of, belong to the field of Chinese medicines.
Background technology
Migraine starts from adolescence more or grows up in early days, is mainly in especially between twenty and fifty period, common with 20～45 years old.Developed country's average attack rate is 12%, and according to incompletely statistics, the migrainous prevalence of China adult reaches 7.7%～18.7%, and is ascendant trend year by year.The migraine frequency is indefinite, and wayward, annual one to for several times to per month one to not waiting for several times, sustainable 4～72 hours of headache outbreak, sustainable 2～3 weeks of outbreak persistent state.Severe headache during migraine, position is fixed, often with nauseating, vomiting, pale complexion, heart rate, tachypnea, the autonomic nerve symptoms such as gastrointestinal dysfunction, 85% women and 82% above male patient's ability to work forfeiture are arranged, having a strong impact on patient's live and work.
In migrainous treatment, doctor trained in Western medicine is commonly used the medicines such as pizotifen, amitriptyline and is treated, and some curative effects are all arranged basically, but can only take stopgap measures, can not effect a permanent cure, and the side effect of these medicines is a lot, especially very large to lesions of liver and kidney, be relief of symptoms, can't play the purpose of thorough healing.
Summary of the invention
The object of the present invention is to provide a kind of good effect, the migrainous Chinese medicine of the treatment had no side effect, the present invention simultaneously also provides a kind of preparation method of this Chinese medicine.
The technology used in the present invention solution is:
A kind ofly treat migrainous Chinese medicine, it is to be made by the raw material of following weight parts proportioning: 10～15 parts, the Radix Rehmanniae, 20～25 parts of Radix Angelicae Sinensis, 15～25 parts, Semen Persicae, 12～15 parts, Flos Carthami, 15～20 parts of Fructus Aurantiis, 20～25 parts of Radix Paeoniae Rubra, 15～20 parts of Radix Bupleuri, 25～30 parts of Rhizoma Chuanxiongs, 15～20 parts of the Radixs Angelicae Dahuricae, 15～20 parts of Flos Chrysanthemis, 10～15 parts of Rhizoma Et Radix Notopterygiis, 20～25 parts of Rhizoma Ligusticis, 20～25 parts of Fructus Viticises, 10～15 parts of Radix Saposhnikoviaes, 18～20 parts of Radix Achyranthis Bidentataes, 15～20 parts of Radix Platycodoniss, 10～15 parts, Radix Glycyrrhizae.
Preferably the weight portion proportioning of each raw material is: 15 parts, the Radix Rehmanniae, 20 parts of Radix Angelicae Sinensis, 15 parts, Semen Persicae, 15 parts, Flos Carthami, 20 parts of Fructus Aurantiis, 20 parts of Radix Paeoniae Rubra, 15 parts of Radix Bupleuri, 30 parts of Rhizoma Chuanxiongs, 20 parts of the Radixs Angelicae Dahuricae, 20 parts of Flos Chrysanthemis, 15 parts of Rhizoma Et Radix Notopterygiis, 20 parts of Rhizoma Ligusticis, 20 parts of Fructus Viticises, 15 parts of Radix Saposhnikoviaes, 20 parts of Radix Achyranthis Bidentataes, 20 parts of Radix Platycodoniss, 15 parts, Radix Glycyrrhizae.
The preparation method of above-mentioned Chinese medicine comprises the following steps:
Take above all medicines by above-mentioned weight portion proportioning and mix, add 8 times of water gagings, soak 2 hours, heating decocts 1.5 hours, gets decoction liquor; Residue adds 8 times of water gagings again, and heating decocts 1 hour, gets decoction liquor; Merge decoction liquor, be concentrated into 2/3rds amounts, standing 24 hours, get supernatant; Heating is concentrated into equivalent extract, and it is 1.25～1.3 that heat is surveyed proportion; Add dextrin, the agent of correctives granulation, meter, get 1 part of equivalent extract by weight ratio again, adds each 2.5 parts of dextrin, correctivess, dries, and gets product.
Above-mentioned Chinese medicine also can be made said peroral dosage form on any pharmaceutics according to conventional methods.
Pharmacology of the present invention and effect are as follows:
The present invention can effectively treat migraine, and the migraine especially caused because of stagnation of QI due to depression of the liver, obstruction of collaterals by blood stasis, headache, trigeminal neuralgia and neurasthenic syndrome are evident in efficacy, have no side effect, safe, taking convenience, and price is low.
Semen Persicae in side, the Flos Carthami removing blood stasis is monarch drug.Radix Angelicae Sinensis, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Rhizoma Chuanxiong helps the power of invigorating blood circulation, and the merit nourished blood is arranged simultaneously, is all ministerial drug.The Radix Achyranthis Bidentatae promoting blood circulation, draw congestion descending in addition; Radix Bupleuri, the Flos Chrysanthemi depressed liver-energy dispersing and QI regulating, rise and reach sun clearly; The up clear key in a mansion that reaches of Radix Platycodonis priming; Fructus Aurantii Immaturus is opened the breast sending down the abnormal ascending QI, the capable blood of gas; Radix Rehmanniae heat clearing and blood cooling, except stagnant heat, is all adjuvant drug.The Radix Angelicae Dahuricae, Rhizoma Et Radix Notopterygii, Rhizoma Ligustici, Fructus Viticis, Radix Saposhnikoviae is guiding drug (priming arrives the medicine of head meridians), with stopping head pain; The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, it is for making medicine.Therefore our nourshing blood and promoting blood circulation, heat clearing away is soothing the liver, and the harmonizing the liver and spleen effect is arranged, and all medicine compatibilities, become blood circulation and removing stasis altogether, regulates the flow of vital energy soothing the liver.We take blood circulation promoting and blood stasis dispelling and just do not hinder, depressed liver-energy dispersing and QI regulating and do not consume gas as characteristics, reach use invigorate blood circulation, the effect of stasis-dispelling and pain-killing.
Above-mentioned all medicine combinations, also have blood circulation promoting and blood stasis dispelling in addition, improves microcirculation, increases the effect of histoorgan blood perfusion amount.Make the release balanced action of endotheliocyte ET/NO and reduce its impact on anticoagulant, fibrinolytic function, Human Umbilical Vein Endothelial Cells plays certain protective effect.
Clinical observation:
(1) clinical data
200 routine migraineurs are carried out to clinical observation treatment, male 85 examples wherein, female's 115 examples, the age is between 14～75 years old.
(2) Therapeutic Method
The Chinese medicine granules of the present invention of taking after mixing it with water, sooner or later each once, each 40g, one after each meal.Patients with mild was taken about 60 days, and the severe case took about 100 days.
(3) curative effect determinate standard
Cure: migraine and related symptoms all disappear, and do not affect activity and work, follow up a case by regular visits to 3 months without recurrence.
Produce effects: migraine and related symptoms disappear substantially, and after treatment, symptom obviously alleviates, and does not affect daily life and work.
Effectively: related symptoms and sign are improved, but unstable condition has recurrence after drug withdrawal.
Invalid: unchanged or counter the increasing the weight of of clinical symptoms and sign.
(4) clinical effectiveness
Clinical cure 173 examples (86.5%), produce effects 17 examples (8.5%), effective 9 examples (4.5%), invalid 1 example (0.5%), total effective rate is 99.5%.
Model case
Zhang, the female, 47 years old, the workman, because of overworked burst migraine, with singultus uncomfortable in chest, the insomnia symptom such as be insomnia, the dark violet spottiness of body of the tongue or ecchymosis, stringy and hesitant pulse.Through taking granule of the present invention 30, sx↓, take again recovery from illness on the 30th.Follow up a case by regular visits to after 1 year, have no recurrence.
The specific embodiment
Embodiment 1
Take each raw material of Chinese medicine by following proportioning:
Radix Rehmanniae 15g, Radix Angelicae Sinensis 20g, Semen Persicae 15g, Flos Carthami 15g, Fructus Aurantii 20g, Radix Paeoniae Rubra 20g, Radix Bupleuri 15g, Rhizoma Chuanxiong 30g, Radix Angelicae Dahuricae 20g, Flos Chrysanthemi 20g, Rhizoma Et Radix Notopterygii 15g, Rhizoma Ligustici 20g, Fructus Viticis 20g, Radix Saposhnikoviae 15g, Radix Achyranthis Bidentatae 20g, Radix Platycodonis 20g, Radix Glycyrrhizae 15g.
Preparation method is as follows:
All medicines after above weighing are mixed, and meter adds 8 times of water gagings by weight ratio, soaks 2 hours, and heating decocts 1.5 hours, gets decoction liquor.Residue adds 8 times of water gagings again, and heating decocts 1 hour, gets decoction liquor.Merge decoction liquor, be concentrated into 2/3rds amounts, standing 24 hours, get supernatant.Heating is concentrated into equivalent extract, and it is 1.25 that heat is surveyed proportion.Add dextrin, the agent of correctives granulation, meter, get 1 part of equivalent extract by weight ratio again, adds each 2.5 parts of dextrin, correctivess, dries, and gets product.
Embodiment 2
Take each raw material of Chinese medicine by following proportioning:
Radix Rehmanniae 15g, Radix Angelicae Sinensis 25g, Semen Persicae 20g, Flos Carthami 12g, Fructus Aurantii 20g, Radix Paeoniae Rubra 25g, Radix Bupleuri 18g, Rhizoma Chuanxiong 30g, Radix Angelicae Dahuricae 15g, Flos Chrysanthemi 20g, Rhizoma Et Radix Notopterygii 12g, Rhizoma Ligustici 20g, Fructus Viticis 25g, Radix Saposhnikoviae 15g, Radix Achyranthis Bidentatae 20g, Radix Platycodonis 15g, Radix Glycyrrhizae 10g.
Preparation method is with embodiment 1.
Embodiment 3
Take each raw material of Chinese medicine by following proportioning:
Radix Rehmanniae 10g, Radix Angelicae Sinensis 20g, Semen Persicae 25g, Flos Carthami 15g, Fructus Aurantii 15g, Radix Paeoniae Rubra 20g, Radix Bupleuri 15g, Rhizoma Chuanxiong 25g, Radix Angelicae Dahuricae 20g, Flos Chrysanthemi 15g, Rhizoma Et Radix Notopterygii 10g, Rhizoma Ligustici 25g, Fructus Viticis 20g, Radix Saposhnikoviae 10g, Radix Achyranthis Bidentatae 20g, Radix Platycodonis 15g, Radix Glycyrrhizae 15g.
Preparation method is with embodiment 1.
Claims (4)
1. the migrainous Chinese medicine for the treatment of, is characterized in that it is to be made by the raw material of following weight parts proportioning: 10～15 parts, the Radix Rehmanniae, 20～25 parts of Radix Angelicae Sinensis, 15～25 parts, Semen Persicae, 12～15 parts, Flos Carthami, 15～20 parts of Fructus Aurantiis, 20～25 parts of Radix Paeoniae Rubra, 15～20 parts of Radix Bupleuri, 25～30 parts of Rhizoma Chuanxiongs, 15～20 parts of the Radixs Angelicae Dahuricae, 15～20 parts of Flos Chrysanthemis, 10～15 parts of Rhizoma Et Radix Notopterygiis, 20～25 parts of Rhizoma Ligusticis, 20～25 parts of Fructus Viticises, 10～15 parts of Radix Saposhnikoviaes, 18～20 parts of Radix Achyranthis Bidentataes, 15～20 parts of Radix Platycodoniss, 10～15 parts, Radix Glycyrrhizae.
2. a kind of migrainous Chinese medicine for the treatment of according to claim 1, wherein the weight portion proportioning of each raw material is: 15 parts, the Radix Rehmanniae, 20 parts of Radix Angelicae Sinensis, 15 parts, Semen Persicae, 15 parts, Flos Carthami, 20 parts of Fructus Aurantiis, 20 parts of Radix Paeoniae Rubra, 15 parts of Radix Bupleuri, 30 parts of Rhizoma Chuanxiongs, 20 parts of the Radixs Angelicae Dahuricae, 20 parts of Flos Chrysanthemis, 15 parts of Rhizoma Et Radix Notopterygiis, 20 parts of Rhizoma Ligusticis, 20 parts of Fructus Viticises, 15 parts of Radix Saposhnikoviaes, 20 parts of Radix Achyranthis Bidentataes, 20 parts of Radix Platycodoniss, 15 parts, Radix Glycyrrhizae.
3. the preparation method of Chinese medicine as claimed in claim 1 or 2 is characterized in that comprising the following steps:
Take above all medicines by above-mentioned weight portion proportioning and mix, add 8 times of water gagings, soak 2 hours, heating decocts 1.5 hours, gets decoction liquor; Residue adds 8 times of water gagings again, and heating decocts 1 hour, gets decoction liquor; Merge decoction liquor, be concentrated into 2/3rds amounts, standing 24 hours, get supernatant; Heating is concentrated into equivalent extract, and it is 1.25～1.3 that heat is surveyed proportion; Add again dextrin, the agent of correctives granulation, dry, get product.
4. the preparation method of Chinese medicine according to claim 3 is characterized in that: meter by weight ratio, get 1 part of equivalent extract, and add each 2.5 parts of dextrin, correctivess.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104383167A (en) * | 2014-10-24 | 2015-03-04 | 辛海滨 | Chinese and western compound medicinal tablet for treating migraine |
| CN106943490A (en) * | 2017-04-28 | 2017-07-14 | 董早霞 | Wind-expelling pain-stopping Huayu Tang |
Citations (2)
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|---|---|---|---|---|
| CN1267523A (en) * | 2000-02-17 | 2000-09-27 | 贾太平 | Chinese medicine composition for treating intractable headache |
| CN101099763A (en) * | 2006-07-07 | 2008-01-09 | 张仁久 | Traditional Chinese medicine for treating headache |
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2013
- 2013-09-12 CN CN201310413588.9A patent/CN103463313B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1267523A (en) * | 2000-02-17 | 2000-09-27 | 贾太平 | Chinese medicine composition for treating intractable headache |
| CN101099763A (en) * | 2006-07-07 | 2008-01-09 | 张仁久 | Traditional Chinese medicine for treating headache |
Non-Patent Citations (2)
| Title |
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| 孙炳华等: "川芎无愧头痛圣药", 《中国医药指南》 * |
| 邓占会: "血府逐瘀汤加减治疗偏头痛68例", 《中国药物经济学》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104383167A (en) * | 2014-10-24 | 2015-03-04 | 辛海滨 | Chinese and western compound medicinal tablet for treating migraine |
| CN106943490A (en) * | 2017-04-28 | 2017-07-14 | 董早霞 | Wind-expelling pain-stopping Huayu Tang |
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| CN103463313B (en) | 2015-12-09 |
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Inventor after: Luan Fuqi Inventor after: Chen Xiaolu Inventor after: Zhang Yonglei Inventor before: Luan Fuqi Inventor before: Zhang Yonglei |
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