CN103768366B - Traditional Chinese medicine preparation for treating proliferation of mammary gland - Google Patents

Traditional Chinese medicine preparation for treating proliferation of mammary gland Download PDF

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Publication number
CN103768366B
CN103768366B CN201410007274.3A CN201410007274A CN103768366B CN 103768366 B CN103768366 B CN 103768366B CN 201410007274 A CN201410007274 A CN 201410007274A CN 103768366 B CN103768366 B CN 103768366B
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chinese medicine
medicine preparation
traditional chinese
radix
mammary gland
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Expired - Fee Related
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CN201410007274.3A
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CN103768366A (en
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栾晓东
盖延红
王炳高
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Qingdao Central Hospital
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Qingdao Central Hospital
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Abstract

The invention relates to a traditional Chinese medicine preparation, and particularly relates to a traditional Chinese medicine preparation for treating proliferation of mammary gland. The traditional Chinese medicine preparation is prepared from the following components: 12g of radix bupleuri, 10g of radix paeoniae alba, 12g of fructus aurantii, 10g of angelica sinensis, 10g of poria cocos, 12g of bighead atractylodes rhizome, 15g of prepared rhizoma cyperi with vinegar, 12g of pericarpium citri reticulatae viride, 20g of salvia miltiorrhiza, 15g of lumbricus, 12g of bulbus fritilariae, 30g of oyster, 15g of endothelium corneum gigeriae galli, 12g of szechwan chinaberry fruit, 20g of snakegourd fruit and 6g of licorice. The traditional Chinese medicine preparation is simple in process, convenient for treatment and low in cost, has the effects of soothing liver for smoothing Qi, regulating the function of the liver and stomach, invigorating the spleen, nourishing blood, softening hardness and dissipating binds and no toxic or side effects and can be used for effectively healing the proliferation of mammary gland.

Description

A kind of Chinese medicine preparation for the treatment of cyclomastopathy
Technical field
The present invention relates to Chinese medicine preparation, particularly a kind of Chinese medicine preparation for the treatment of cyclomastopathy.
Background technology
Cyclomastopathy refers to breast epithelium and proliferation of fibrous tissue, mammary gland tissue conduit and newborn lobule degeneration structurally and the growth of carrying out property connective tissue, and its pathogenic factor is mainly due to endocrine hormone imbalance.
Cyclomastopathy is middle-aged women common disease, and this disease is because of female in body, progesterone level imbalance, causes mammary gland essence hypertrophy and subinvolution in various degree.Clinical manifestation is distending pain of the breast and lump, often relevant with menstrual cycle, before menstrual period, increases the weight of, and a few patients can canceration.
Summary of the invention
For the defect existing in prior art, the object of the present invention is to provide a kind of treat curing mammary gland hyperplasia obtain effective, instant effect, the Chinese medicine preparation that cure rate is high.
For reaching above object, the technical scheme that the present invention takes is:
Treat a Chinese medicine preparation for cyclomastopathy, composed of the following components: Radix Bupleuri 12g, Radix Paeoniae Alba 10g, Fructus Aurantii 12g, Radix Angelicae Sinensis 10g, Poria 10g, Rhizoma Atractylodis Macrocephalae 12g, Rhizoma Cyperi (processed with vinegar) 15g, Pericarpium Citri Reticulatae Viride 12g, Radix Salviae Miltiorrhizae 20g, Pheretima 15g, Bulbus Fritillariae Cirrhosae 12g, Concha Ostreae 30g, Endothelium Corneum Gigeriae Galli 15g, Fructus Toosendan 12g, Fructus Trichosanthis 20g, Radix Glycyrrhizae 6g.
Preparation method: take mixing according to said ratio, soak 2 hours post-heating, heat is opened rear decoction 20 minutes, leaches medicine juice, then decocts with water 20 minutes, leaches medicine juice, leaches medicine juice for twice and mixes.
Radix Bupleuri: dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.Distending pain in the chest and hypochondrium due to treatment depression of liver-QI.
The Radix Paeoniae Alba: nourishing blood for regulating menstruation, easing the affected liver to relieve pain, yin nourishing suppressing the hyperactive liver.The breast side of body gastralgia for the treatment of disharmony in liver-QI.
Fructus Aurantii: dispelling the stagnated QI removing food stagnancy, dissipating phlegm and resolving masses.The internal resistance for the treatment of cold-phlegm, hypofunction of YANG QI in chest, expectorant accumulation of heat in chest, breast gastral cavity painful abdominal mass pain.
Radix Angelicae Sinensis: tonifying blood and regulating menstruation, promoting blood circulation and stopping pain.Treatment blood deficiency, congestion is had a pain.
Poria: promoting diuresis to eliminate damp pathogen, spleen invigorating and in.Treat insufficiency of the spleen asthenia.
The Rhizoma Atractylodis Macrocephalae: invigorating the spleen and benefiting QI, dampness diuretic.Treatment weakness of the spleen and stomach, insufficiency of the spleen leading to overabundance of dampness, phlegm retention edema.
Rhizoma Cyperi (processed with vinegar): the resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving.Treatment stagnation of QI due to depression of the liver, chest and hypochondrium, abdominal distention.
Pericarpium Citri Reticulatae Viride: soothing the liver dispelling the stagnated QI, removing food stagnancyization is stagnant.Treatment distending pain in the chest and hypochondrium, distending pain of the breast.
Radix Salviae Miltiorrhizae: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow.Be used for the treatment of blood stasis amenorrhea, trusted subordinate's twinge.
Pheretima: suppressing the hyperactive liver dredging collateral.Treatment blood stagnancy due to deficiency of QI, dredge the meridian passage.
Bulbus Fritillariae Cirrhosae: preventing phlegm from forming and stopping coughing.Treatment scrofula carbuncle.
Concha Ostreae: hard masses softening and resolving.Treatment scrofula goiter.
Endothelium Corneum Gigeriae Galli: strengthening the spleen to promote digestion.Treatment dyspepsia.
Fructus Toosendan: soothing the liver promoting the circulation of QI to relieve pain.The treatment breast side of body is had a pain, abdominal distention, stagnation of liver-QI and stomach-QI.
Fructus Trichosanthis: clearing away heat and eliminating phlegm, promoting the circulation of QI the chest stuffiness relieving, dispersing swelling and dissipating binds.The treatment treatment thoracic obstruction, blocked-up chest, acute mastitis swells and ache.
Radix Glycyrrhizae: invigorating the spleen and replenishing QI relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Treatment deficiency of spleen-QI and stomach-QI, relaxes the property of medicine, coordinating the actions of various ingredients in a prescription.
Chinese medicine thinks, primary disease is due to Chong and Ren channel disorder, incoordination between the liver and stomach, and stagnation of QI due to depression of the liver, qi stagnation blood stasis expectorant is solidifying and fall ill.
The Chinese medicine preparation for the treatment of cyclomastopathy of the present invention, adopts the method treatment of dispersing the stagnated live-QI to relieve the stagnation of QI, nourish blood spleen invigorating regulating menstruation, dissipating phlegm and resolving masses, Chong and Ren Meridians regulating.Selecting Radix Bupleuri, Fructus Aurantii, Rhizoma Cyperi (processed with vinegar) is monarch drug, depressed liver-energy dispersing and QI regulating resolving depression; Minister is with Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae promoting blood circulation to remove blood stasis, and minister is with the soothing the liver dispelling the stagnated QI removing food stagnancy of Pericarpium Citri Reticulatae Viride, and minister is with Concha Ostreae hard masses softening and resolving, and assistant wets with the Rhizoma Atractylodis Macrocephalae, Poria, Endothelium Corneum Gigeriae Galli invigorating the spleen for dissipating phlegm; Assistant is reduced phlegm wet with Bulbus Fritillariae Cirrhosae, assistant is with Pheretima dredge the meridian passage, and assistant is with Fructus Toosendan, Fructus Trichosanthis pain relieving; Make with Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.All medicines share, and play the effect of depressed liver-energy dispersing and QI regulating, harmonizing the liver and stomach, strengthening spleen and nourishing blood, hard masses softening and resolving.
With the party, treat cyclomastopathy patient 385 examples clinically, effective percentage is 85.5%.Technique of the present invention is simple, and treatment is convenient, has no side effect, and cost is low.
The specific embodiment
Treat a Chinese medicine preparation for cyclomastopathy, composed of the following components: Radix Bupleuri 12g, Radix Paeoniae Alba 10g, Fructus Aurantii 12g, Radix Angelicae Sinensis 10g, Poria 10g, Rhizoma Atractylodis Macrocephalae 12g, Rhizoma Cyperi (processed with vinegar) 15g, Pericarpium Citri Reticulatae Viride 12g, Radix Salviae Miltiorrhizae 20g, Pheretima 15g, Bulbus Fritillariae Cirrhosae 12g, Concha Ostreae 30g, Endothelium Corneum Gigeriae Galli 15g, Fructus Toosendan 12g, Fructus Trichosanthis 20g, Radix Glycyrrhizae 6g.
Preparation method: take mixing according to said ratio, soak 2 hours post-heating, heat is opened rear decoction 20 minutes, leaches medicine juice, then decocts with water 20 minutes, leaches medicine juice, leaches medicine juice for twice and mixes.
Usage and dosage: 1 week after menstruation starts to take medicine, every day potion, decoction being taken warmly at twice, serveing on 14 days is 1 course for the treatment of, meets menstrual onset and cuts out.
As follows to pharmacodynamic analysis of the present invention:
1, criterion of therapeutical effect:
Cure: lump and pain symptom all disappear.
Alleviate: lump partly disappears or pain relief.
Effective: to cure+alleviate.
Invalid: lump and pain symptom are not improved.
2, therapeutic outcome:
Instructions of taking: every day potion, warm use at twice, medication 30 days.
With the party, treat cyclomastopathy patient 385 examples clinically, at 26-57 years old ages, 43 years old mean age, total effective rate is 85.5%.
Total number of cases Cure (%) Alleviate (%) Total effectively (%)
385 82(21.3) 247(64.2) 329(85.5%)
Model case:
1, Lee, female, 48 years old, bilateral distending pain of the breast 1 year, before increase the weight of nearly January.Look into dark tongue quality, yellow and greasy fur, stringy pulse, two newborn diffusivity lumps, touch a tender spot.Breast molybdenum target checks: bilateral breast hypertrophy.Diagnosis: cyclomastopathy.Chinese medical discrimination is qi depression to blood stasis, combination of phlegm and heat.With after 7 doses of the party, two mammary swelling alleviation of pain are light, and two swelling of the breast pieces dwindle, and continue with 21 doses of the party, and two newborn pain, two swelling of the breast piece all disappear, and body of the tongue is light red, white and thin fur, stringy pulse, breast molybdenum target inspection: two newborn no abnormality seens.Follow up a case by regular visits to and do not recur half a year.
2, Wang, female, 42 years old, bilateral distending pain of the breast June, companion's susceptible to lose temper due to restlessness, when angry, two mammary swellings increase the weight of bitterly.Purplish tongue, yellow and thin fur, stringy pulse, the outside upper lump of two breasts is touched a tender spot obviously, and mammary gland B ultrasonic, molybdenum target inspection are bilateral breast hypertrophy.Diagnosis: cyclomastopathy.Chinese medical discrimination stagnation of QI due to depression of the liver blood stasis, Chong and Ren channel disorder.With after 5 doses of the party, two mammary swelling alleviation of pain are light, continue with 9 doses of the party, and two newborn pain, two swelling of the breast piece all disappear, light red tongue, white and thin fur, normal pulse, mammary gland B ultrasonic, molybdenum target inspection: two newborn no abnormality seens.Follow up a case by regular visits to and do not recur half a year.
3, thank certain, female, 36 years old, bilateral distending pain of the breast March, month premenstrual increasing the weight of.Purplish tongue has ecchymosis, yellow and thin fur, and deep pulse, two breasts are touched a tender spot obviously, and mammary gland B ultrasonic, molybdenum target inspection are bilateral breast hypertrophy.Diagnosis: cyclomastopathy.Chinese medical discrimination stagnation of QI due to depression of the liver, incoordination between the liver and stomach, blood stasis expectorant are solidifying, and with after 10 doses of the party, two mammary swelling alleviation of pain are light, continue with 18 doses of the party, and two newborn pain disappears, light red tongue, white and thin fur, normal pulse, mammary gland B ultrasonic, molybdenum target inspection: two newborn no abnormality seens.Follow up a case by regular visits to not recurrence in 1 year.

Claims (1)

1. treat a Chinese medicine preparation for cyclomastopathy, composed of the following components: Radix Bupleuri 12g, Radix Paeoniae Alba 10g, Fructus Aurantii 12g, Radix Angelicae Sinensis 10g, Poria 10g, Rhizoma Atractylodis Macrocephalae 12g, Rhizoma Cyperi (processed with vinegar) 15g, Pericarpium Citri Reticulatae Viride 12g, Radix Salviae Miltiorrhizae 20g, Pheretima 15g, Bulbus Fritillariae Cirrhosae 12g, Concha Ostreae 30g, Endothelium Corneum Gigeriae Galli 15g, Fructus Toosendan 12g, Fructus Trichosanthis 20g, Radix Glycyrrhizae 6g.
CN201410007274.3A 2014-01-08 2014-01-08 Traditional Chinese medicine preparation for treating proliferation of mammary gland Expired - Fee Related CN103768366B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1220163A (en) * 1998-11-12 1999-06-23 东莞市亚洲制药有限公司 Drug for curing premenstrual tension
CN101085303A (en) * 2007-06-29 2007-12-12 牟培锐 Oral administration traditional Chinese medicine composition for treating hyperplasia of mammary glands
CN101559204A (en) * 2009-05-22 2009-10-21 邓丽菊 Traditional Chinese medicine compound treating irregular menstruation and dysmenorrheal and application thereof in preparing hygienic products of women

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1220163A (en) * 1998-11-12 1999-06-23 东莞市亚洲制药有限公司 Drug for curing premenstrual tension
CN101085303A (en) * 2007-06-29 2007-12-12 牟培锐 Oral administration traditional Chinese medicine composition for treating hyperplasia of mammary glands
CN101559204A (en) * 2009-05-22 2009-10-21 邓丽菊 Traditional Chinese medicine compound treating irregular menstruation and dysmenorrheal and application thereof in preparing hygienic products of women

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
对乳腺癌西医治疗过程中不良反应的中药治验;郭海涛等;《光明中医》;20130120;第28卷(第1期);101 *
郭海涛等.对乳腺癌西医治疗过程中不良反应的中药治验.《光明中医》.2013,第28卷(第1期),101.

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