CN103446335A - Conidial powder tablet with lucid ganoderma extract - Google Patents

Conidial powder tablet with lucid ganoderma extract Download PDF

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Publication number
CN103446335A
CN103446335A CN2013103185397A CN201310318539A CN103446335A CN 103446335 A CN103446335 A CN 103446335A CN 2013103185397 A CN2013103185397 A CN 2013103185397A CN 201310318539 A CN201310318539 A CN 201310318539A CN 103446335 A CN103446335 A CN 103446335A
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China
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parts
ganoderma extract
ganoderma
tablet
mentioned
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CN2013103185397A
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Chinese (zh)
Inventor
柳艳
王其初
贾虎
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ANHUI HARBAUGH PHARMACEUTICAL Co Ltd
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ANHUI HARBAUGH PHARMACEUTICAL Co Ltd
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Priority to CN2013103185397A priority Critical patent/CN103446335A/en
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Abstract

The invention discloses a conidial powder tablet with a lucid ganoderma extract. The tablet consists of the following raw materials in parts by weight: 60-70 parts of the lucid ganoderma extract, 50-60 parts of ganoderma lucidum spore powder, 6-10 parts of starch, 1-2 parts of magnesium stearate, 2-3 parts of agaric, 1-2 parts of astragalus membranaceus, 1-2 parts of ginseng, 1-2 parts of rhizoma atractylodis macrocephalae, 2-3 parts of arundina graminifolia, 4-6 parts of tomatoes, 1-2 parts of limonium bicolor, 2-3 parts of Chinese wampee leaves, 2-4 parts of sweet potato leaves, 2-3 parts of glossy privet fruits and 1-2 parts of chestnut leaves. The conidial powder tablet with the lucid ganoderma extract disclosed by the invention has very high effect of boosting immunity. The astragalus membranaceus has the effects of boosting immunity of a human body, protecting liver, inducing diuresis, resisting aging, resisting stress and reducing blood pressure and having a wider antibacterial effect, and agaric, ginseng, rhizoma atractylodis Macrocephalae and the like have a certain effect of boosting immunity.

Description

A kind of Ganoderma extract spore tablet
Technical field
The present invention relates generally to a kind of spore tablet, relates in particular to a kind of Ganoderma extract spore tablet.
Background technology
Active anticancer
The cancer research of animal (for example: rat connective tissue cancer model) be presented at after utilizing Ganoderma extract treatment 50% tumor decline ratio is arranged.Ganoderma extract is used for the treatment of the cancer patient by Japanese part surgeon, and notices its significant antitumor and immunostimulation in numerous cases.The polysaccharide separated from the medicinal mushroom of Ganoderma and other has obtained patent in Japan and be used as immunomodulator in treatment of cancer.It is mixed with chemistry or X-ray therapy and demonstrate the minimizing side effect, promotes the ability of therapeutic effect, and is used to promote rehabilitation.
The Ganoderma extract that studies show that of China has been strengthened the anti-tumor capacity of macrophage and T-cell.Ganoderma extract is known also has other immunoregulation effect and anti-oxidant properties.But zooscopy show equally Ganoderma polysaccharide part inducing leukemia cell apoptosis (programmed death of cancer cell) and when utilizing the ganoderan treatment, induced the leukaemia of 40%-45% cell differentiation to occur, prove its obvious treatment of cancer potentiality.These effects are main because ganoderan induces the antitumor cell factor (signal agency) secretion of generation to rise, i.e. TNF-alpha and IFN-gamma, and also these two kinds of cytokines are to show cooperative effect suppressing that the leukaemia grows.In correlation test, the D-glucosan polysaccharide of Ganoderma part demonstrates and produces theatrical tumor and fail to the research of rat malignant tumor the time.With it many laboratory animals, selected colony to occur the decline fully of tumor after 5 weeks in injection beta-D glucosan polysaccharide part.Y. Song waits the experiment carry out to report infected animal 90% tumor suppression ratio and 75% tumor decline with it.
Improve immune system: (bronchitis, asthma, nasal allergy disease, herpetic disease and HIV infect)
Numerous constituents of Ganoderma extract immunity-regulating system, wherein part is considered to have obvious antitumor properties.In the experiment that once comprises 2000 cases of China, utilize to concentrate after Garnoderma product is treated senile chronic bronchitis to demonstrate good reaction.This studies show that the Success Ratio that surpasses 60%.After the treatment of several months, obvious rising has appearred in the immunoglobulin A level of apoplexy due to phlegm.Immunoglobulin A is the main immunoglobulin of finding in respiratory tract.Nasal allergy disease, in systemic lupus and rheumatoid arthritis, it generally there will be deficiency.The Ganoderma extract supplement once showed and improved asthma and nasal allergy symptom.Two kinds of important component of Ganoderma extract, oleic acid and ring eight sulfur show the release that can suppress histamine, this may be for what being of value to the reason of asthma, a kind of special proteoglycan that is called as Glhw-02 in Ganoderma extract demonstrates the ntiviral characteristic that has effective antagonism 1 type and 2 type pure viruses under laboratory condition simultaneously.Once small-scale human experimentation shows that Ganoderma extract " dramatically " has reduced two postherpetic neuralgia patients' pain and having an intense pain of another two bit strip shape herpes infections (herpes zoster, because herpesvirus causes) patient.
Under laboratory condition, in Ganoderma extract, multiple Ganodenic acid and polysaccharide demonstration can be used as active anti-HIV material, and show under conservative dose and to reduce virus replication and reach 50% ability, after mixing with other east medicinal herbs, Ganoderma is used to now to AIDS related complex, the treatment of AIDS, and separately or+with the mixed treatment of other medical material chronic fatigue syndrome.
Cardiovascular health: (hypertension and minimizing platelet aggregation)
Twice controlled human experimentation shows that Ganoderma extract can reduce hypertension to extremely obvious degree (systolic pressure and cardiac dilatation are pressed), even for before those for the unresponsive patient of known antihypertensive drugs.Zoopery shows that Ganoderma extract reduces blood pressure by the central inhibitory action of right sympathetic activity, although this effect basically can not make decreased heart rate or cause sedation effect.Under laboratory environment, Ganoderma extract has slightly builds up effect to the less platelet of moderate, and this function in the future may be helpful to reducing the trouble risk of cardiovascular diseases.Its same demonstration can increase endurance, and blood flows into the brain flow and improves the Oxygenation of cell.Similarly, it contributes to the energy of cellular level synthetic, its may improve cardiovascular health and in some culture for promoting memory and intelligence, comprising the successful utilization in Alzheimer disease patient research.
Liver protection effect (hepatoprotective characteristic)
Ganoderma is used for chronic and treatment acute hepatitis as prescription drugs in China.Multiple polysaccharide in Ganoderma has very strong anti-hepatotoxin characteristic, and the liver protection effect that it demonstrates under the chemical induction injury under laboratory environment, comprise the protective effect to high toxicity and lifetime killer carbon tetrachloride.
Support nervous system
Ganoderma is recommended the insomnia for coming because of its " sleep promoting element " by the China and Japan herb doctor traditionally.Life-time service can cause the obvious promotion to S sleep.Be used as prescription drugs for much psychiatry and neurological problem Chinese Ganoderma, comprising muscle disease, weak after loss of appetite and prolonged sickness.
Antiallergic/anti-inflammatory effect
In the seventies and the eighties, the anti-allergic effects of Ganoderma becomes the problem of the ongoing research of China and Japan.Studies show that Ganoderma extract obviously suppresses all four class allergy, comprises the positive role to asthma and contact dermatitis.In nineteen ninety, scientist in University of Texas's health sciences center of San Antonio finds that Ganoderma can be used for the treatment of Wry Neck effectively, shoulder is stiff, conjunctivitis (being lining in mocromembrane in eyes and eyelid is inflamed), bronchitis, rheumatism and in the situation that do not have apparent side effect to improve the immune system ability.
The anti-inflammatory ability part of Ganoderma may be because of its radical scavenging activity.Ganoderma extract obviously promotes the radical scavenging activity of blood, particularly resists harmful significantly hydroxy radical.The hydroxy radical removing ability of Ganoderma be so powerful so that Ganoderma extract be absorbed with metabolic alterations after its scavenging action still continue.
Defying age
The classical Sheng Nong's herbal classic record of medicine in the time immemorial Ganoderma of China can effectively strengthen life energy (gas), increases ability of thinking and prevents forgetful.It can recover body and intelligence, slow down aging and make the mankind can extending life.
Summary of the invention
The object of the invention just is to provide a kind of Ganoderma extract spore tablet.
The present invention is achieved by the following technical solutions:
A kind of Ganoderma extract spore tablet, it is comprised of the raw material of following weight parts:
Ganoderma extract 60-70, Ganoderma spore powder 50-60, starch 6-10, magnesium stearate 1-2, Auricularia 2-3, Radix Astragali 1-2, Radix Ginseng 1-2, Rhizoma Atractylodis Macrocephalae 1-2, Herba Murdanniae Divergentis 2-3, Fructus Lycopersici esculenti 4-6, Herba Limoii Bicoloris 1-2, Folium clausenae lansii 2-3, Folium Ipomoea 2-4, Fructus Ligustri Lucidi 2-3, Folium Castaneae 1-2.
A kind of preparation method of Ganoderma extract spore tablet comprises the following steps:
(1) above-mentioned Ganoderma extract, Ganoderma spore powder are mixed, cross the 60-80 mesh sieve;
(2) the above-mentioned Radix Astragali, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, Herba Murdanniae Divergentis, Herba Limoii Bicoloris, Folium clausenae lansii, Folium Ipomoea, Fructus Ligustri Lucidi, Folium Castaneae are mixed, extracting in water, filter merging filtrate;
(3) 10-15% of above-mentioned starch weight is joined in above-mentioned filtrate, make the starch slurry that concentration is 8-10%, add Fructus Lycopersici esculenti, milled mixture;
(4) each raw material after above-mentioned processing is mixed with each raw material except magnesium stearate; stir 10-15 minute, cross the 15-20 mesh sieve, obtain wet granular; 50-70 ℃ of lower dried 3-10 minute; magnesium stearate is crossed to the 50-70 mesh sieve, mix tabletting with above-mentioned dried granule; every 0.6-0.7g; coating, bottling, obtain described Ganoderma extract spore tablet.
A kind of Ganoderma extract spore tablet, the irreplaceable medicine of Ganoderma extract spore tablet of the present invention, be applicable to the immunocompromised person and take, and every day 2 times, each 2, is not suitable for children, anemia of pregnant woman and wet nurse edible.
Advantage of the present invention is:
Ganoderma extract spore tablet of the present invention has very high enhancing immune effect, wherein the Radix Astragali there is the enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely, Auricularia, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae etc. have certain enhancing immunity effect.
The specific embodiment
Embodiment 1
A kind of Ganoderma extract spore tablet, it is comprised of the raw material of following weight parts (kilogram):
Ganoderma extract 70, Ganoderma spore powder 60, starch 10, magnesium stearate 2, Auricularia 2, the Radix Astragali 1, Radix Ginseng 1, the Rhizoma Atractylodis Macrocephalae 1, Herba Murdanniae Divergentis 3, Fructus Lycopersici esculenti 4, Herba Limoii Bicoloris 1, Folium clausenae lansii 2, Folium Ipomoea 4, Fructus Ligustri Lucidi 2, Folium Castaneae 2.
A kind of preparation method of Ganoderma extract spore tablet comprises the following steps:
(1) above-mentioned Ganoderma extract, Ganoderma spore powder are mixed, cross 80 mesh sieves;
(2) the above-mentioned Radix Astragali, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, Herba Murdanniae Divergentis, Herba Limoii Bicoloris, Folium clausenae lansii, Folium Ipomoea, Fructus Ligustri Lucidi, Folium Castaneae are mixed, extracting in water, filter merging filtrate;
(3) 15% of above-mentioned starch weight is joined in above-mentioned filtrate, make the starch slurry that concentration is 8-10%, add Fructus Lycopersici esculenti, milled mixture;
(4) each raw material after above-mentioned processing is mixed with each raw material except magnesium stearate; stir 15 minutes, cross 20 mesh sieves, obtain wet granular; 70 ℃ of lower dried 10 minutes; magnesium stearate is crossed to 70 mesh sieves, mix tabletting with above-mentioned dried granule; every 0.7g; coating, bottling, obtain described Ganoderma extract spore tablet.
A kind of Ganoderma extract spore tablet, the irreplaceable medicine of Ganoderma extract spore tablet of the present invention, be applicable to the immunocompromised person and take, and every day 2 times, each 2, is not suitable for children, anemia of pregnant woman and wet nurse edible.

Claims (3)

1. a Ganoderma extract spore tablet is characterized in that what it was comprised of the raw material of following weight parts:
Ganoderma extract 60-70, Ganoderma spore powder 50-60, starch 6-10, magnesium stearate 1-2, Auricularia 2-3, Radix Astragali 1-2, Radix Ginseng 1-2, Rhizoma Atractylodis Macrocephalae 1-2, Herba Murdanniae Divergentis 2-3, Fructus Lycopersici esculenti 4-6, Herba Limoii Bicoloris 1-2, Folium clausenae lansii 2-3, Folium Ipomoea 2-4, Fructus Ligustri Lucidi 2-3, Folium Castaneae 1-2.
2. the preparation method of a Ganoderma extract spore tablet as claimed in claim 1 is characterized in that comprising the following steps:
(1) above-mentioned Ganoderma extract, Ganoderma spore powder are mixed, cross the 60-80 mesh sieve;
(2) the above-mentioned Radix Astragali, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, Herba Murdanniae Divergentis, Herba Limoii Bicoloris, Folium clausenae lansii, Folium Ipomoea, Fructus Ligustri Lucidi, Folium Castaneae are mixed, extracting in water, filter merging filtrate;
(3) 10-15% of above-mentioned starch weight is joined in above-mentioned filtrate, make the starch slurry that concentration is 8-10%, add Fructus Lycopersici esculenti, milled mixture;
(4) each raw material after above-mentioned processing is mixed with each raw material except magnesium stearate; stir 10-15 minute, cross the 15-20 mesh sieve, obtain wet granular; 50-70 ℃ of lower dried 3-10 minute; magnesium stearate is crossed to the 50-70 mesh sieve, mix tabletting with above-mentioned dried granule; every 0.6-0.7g; coating, bottling, obtain described Ganoderma extract spore tablet.
3. a kind of Ganoderma extract spore tablet according to claim 1, it is characterized in that the irreplaceable medicine of Ganoderma extract spore tablet of the present invention, be applicable to the immunocompromised person and take, every day 2 times, each 2, be not suitable for children, anemia of pregnant woman and wet nurse edible.
CN2013103185397A 2013-07-26 2013-07-26 Conidial powder tablet with lucid ganoderma extract Pending CN103446335A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111195289A (en) * 2018-11-16 2020-05-26 仙芝科技(福建)股份有限公司 Capsule containing extracts of Ganoderma, Ganoderma spore powder and fructus Ligustri Lucidi, and its preparation method
CN115153023A (en) * 2014-07-02 2022-10-11 嘉康利公司 Compositions and methods for enhancing immunity

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101810336A (en) * 2010-04-30 2010-08-25 广东仙乐制药有限公司 Chewable soft capsules and method for preparing same

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101810336A (en) * 2010-04-30 2010-08-25 广东仙乐制药有限公司 Chewable soft capsules and method for preparing same

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115153023A (en) * 2014-07-02 2022-10-11 嘉康利公司 Compositions and methods for enhancing immunity
CN111195289A (en) * 2018-11-16 2020-05-26 仙芝科技(福建)股份有限公司 Capsule containing extracts of Ganoderma, Ganoderma spore powder and fructus Ligustri Lucidi, and its preparation method
CN111195289B (en) * 2018-11-16 2022-03-29 仙芝科技(福建)股份有限公司 Capsule containing extracts of Ganoderma, Ganoderma spore powder and fructus Ligustri Lucidi, and its preparation method

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Application publication date: 20131218