CN103444995A - Preparation method of acalypha australis extractive grains - Google Patents
Preparation method of acalypha australis extractive grains Download PDFInfo
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- CN103444995A CN103444995A CN2013103429743A CN201310342974A CN103444995A CN 103444995 A CN103444995 A CN 103444995A CN 2013103429743 A CN2013103429743 A CN 2013103429743A CN 201310342974 A CN201310342974 A CN 201310342974A CN 103444995 A CN103444995 A CN 103444995A
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- extract
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- acalypha australis
- acalypha copperleaf
- acalypha
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Abstract
The invention aims to provide a preparation method of acalypha australis extractive grains. According to the preparation method, an acalypha australis extractive is covered by using a macromolecular substance to isolate the acalypha australis extractive from an outer environment, so that the acalypha australis extractive grains do not easily absorb moisture, are not easily caked, have good mobility and have high uniformity after being mixed with a feed. The specific method comprises contents of two aspects including preparation of an acalypha australis extractive extract, and granulation and coating of the acalypha australis extractive, and comprises the following steps: taking acalypha australis as a raw material; adding water with the weight which is five times as much as that of the acalypha australis and immersing for two hours; heating and extracting, wherein the temperature is 100 DEG C and the extraction time is two hours; concentrating an extracting solution until the relative density is 1.182-1.188 to obtain the acalypha australis extractive extract; putting the acalypha australis extractive extract, dextrin and starch into a granulator according to the weight ratio of (0.8-1.2) to (0.4-1.8) to (1.5-2.5) to carry out bottom-spraying granulation; in the granulation process, coating, wherein a coating agent is a 5% acrylic resin solution. Process conditions are as follows: the supply air rate comprises four grades; the air inlet temperature is 45-55 DEG C; the air outlet temperature is 35-45 DEG C; the atomizing pressure is 1.7 bars; the diameter of a nozzle is 0.8mm; the liquid spraying speed is 4ml/min-5ml/min.
Description
Technical field
The present invention relates to a kind of preparation method of acalypha copperleaf extract particles, belong to field of feed additive technology.
Background technology
Acalypha copperleaf is euphorbia plant, and herb is containing acalyphine, and hemostasis, antibiotic, only dysentery, the function such as clearing heat and detoxicating are arranged.The bright juice of multiple extracorporeal bacteria inhibitor test method proof acalypha copperleaf, water decoction, decocting alcohol extract etc. all have obvious bacteriostasis to staphylococcus aureus, staphylococcus albus, hemolytic streptococcus, Escherichia coli, typhoid bacillus, paratyphosum Bacterium, Amur shigella dysenteriae, shigella flexneri, sonne bacillus, Pseudomonas aeruginosa, bacillus enteritidis, cholera fowl Salmonella etc.Thereby acalypha copperleaf is one of Chinese medicine of infecting of the control animal and bird intestines commonly used.
In the actual production practice, for reducing the addition of acalypha copperleaf, normal application acalypha copperleaf extract, yet because the acalypha copperleaf extract very easily absorbs airborne moisture, in the situation that unpack, in a few minutes, the acalypha copperleaf extract can moisture absorption become tide, in dozens of minutes, can lump, use to feed factory and raiser has brought very large difficulty, has had a strong impact on using and promoting of acalypha copperleaf extract.
Summary of the invention
The object of the invention is to the defect for above-mentioned existence, design a kind of preparation method of improved acalypha copperleaf extract particles, after granulating, with polymer substance, the acalypha copperleaf extract is wrapped up, make acalypha copperleaf extract and external environment isolation, be difficult for the moisture absorption, prevented from caking, good fluidity, more even while being mixed with feed.
Technical solution of the present invention: the method comprises following processing step:
1, the preparation of acalypha copperleaf extract medicinal extract: take acalypha copperleaf as raw material, add the water of 5 times of acalypha copperleaf weight first to soak 2 hours, heating is extracted, temperature is 100 ℃, extraction time is 2 hours, then extract is concentrated into to relative density 1.182 ~ 1. 188, obtains acalypha copperleaf extract medicinal extract.
2, the particle of acalypha copperleaf extract and dressing: by acalypha copperleaf extract medicinal extract: dextrin: starch is by weight being (0.8～1.2): (0.4～1.8): (1.5～2.5); put in granulator and carry out end spray grain; granulate and carry out dressing simultaneously; the acrylic resin soln that coating agent is 5% by concentration, obtain acalypha copperleaf extract particles and dressing.
It is characterized in that its process conditions of described granulation and dressing are: intake: 4 grades, 45～55 ℃ of EATs, 35～45 ℃ of leaving air temps, atomizing pressure 1.7bar, nozzle diameter 0.8mm, hydrojet speed 4～5ml/min.
Advantage of the present invention: with polymer substance, the acalypha copperleaf extract is wrapped up, make acalypha copperleaf extract and external environment isolation, protected the active ingredient of acalypha copperleaf extract.When acalypha copperleaf extract and feeding animals after feed is mixed, polymeric membrane dissolves gradually in animal gastrointestinal tract, and the acalypha copperleaf extract progressively discharges the performance drug effect.
specific implementation method:
embodiment 1:
Add 5 times of water soakings 2 hours with the acalypha copperleaf of 100kg; heating is extracted; temperature is 100 ℃; extraction time is 2 hours; it is 1.182 ~ 1.188 that the extract heating is concentrated into to relative density, obtains acalypha copperleaf extract medicinal extract 30kg, then adds 15kg dextrin, 60kg starch; put in granulator and granulated and dressing, the acrylic resin soln that coating agent is 5% concentration.Process conditions are: intake is 4 grades, 45 ~ 55 ℃ of EATs, 35 ~ 45 ℃ of leaving air temps, atomizing pressure 1.7bar, nozzle diameter 0.8mm, hydrojet speed 4 ~ 5ml/min.
embodiment 2:
Add 5 times of water soakings 2 hours with the acalypha copperleaf of 100kg; heating is extracted; temperature is 100 ℃; extraction time is 2 hours; it is 1.182 ~ 1.188 that the extract heating is concentrated into to relative density, obtains acalypha copperleaf extract medicinal extract 30kg, then adds 45kg dextrin, 62.4kg starch; put in granulator and granulated and dressing, the acrylic resin soln that coating agent is 5% concentration.Process conditions are: intake: 4 grades, and 45 ~ 55 ℃ of EATs, 35 ~ 45 ℃ of leaving air temps, atomizing pressure 1.7bar, nozzle diameter 0.8mm, hydrojet speed 4 ~ 5 ml/min.
embodiment 3:
Add 5 times of water soakings 2 hours with the acalypha copperleaf of 80kg; heating is extracted; temperature is 100 ℃; extraction time is 2 hours; it is 1.182 ~ 1.188 that extract heating is concentrated into to relative density, by the acalypha copperleaf extract medicinal extract 30kg obtained, then adds 33kg and enters dextrin, starch 60kg; put in granulator and granulated and dressing, coating agent acrylic resin soln concentration is 5%.Process conditions are: intake is 4 grades, 45 ~ 55 ℃ of EATs, 35 ~ 45 ℃ of leaving air temps, atomizing pressure 1.7bar, nozzle diameter 0.8mm, hydrojet speed 4 ~ 5 ml/min.
Claims (2)
1. the preparation method of an acalypha copperleaf extract particles, it is characterized in that the method comprises following processing step: the preparation of (1) acalypha copperleaf extract medicinal extract: take acalypha copperleaf as raw material, add the water soaking of 5 times of acalypha copperleaf weight to heat extraction after 2 hours, temperature is 100 ℃, extraction time is 2 hours, extract is concentrated into to relative density 1.182～1.188, obtains acalypha copperleaf extract medicinal extract.(2) granulation of acalypha copperleaf extract and dressing: by acalypha copperleaf extract medicinal extract: dextrin: starch is by weight being (0.8～1.2): (0.4～1.8): (1.5～2.5); put in granulator and carry out end spray grain; granulate and carry out dressing simultaneously; the acrylic resin soln that coating agent is 5% concentration, obtain acalypha copperleaf extract particles and dressing.
2. the preparation method of a kind of acalypha copperleaf extract particles according to claim 1, it is characterized in that described granulation and art for coating condition are as follows: intake: 4 grades, 45～55 ℃ of EATs, 35～45 ℃ of leaving air temps, atomizing pressure 1.7bar, nozzle diameter 0.8mm, hydrojet speed 4～5ml/min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013103429743A CN103444995A (en) | 2013-08-08 | 2013-08-08 | Preparation method of acalypha australis extractive grains |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2013103429743A CN103444995A (en) | 2013-08-08 | 2013-08-08 | Preparation method of acalypha australis extractive grains |
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| CN103444995A true CN103444995A (en) | 2013-12-18 |
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| CN2013103429743A Pending CN103444995A (en) | 2013-08-08 | 2013-08-08 | Preparation method of acalypha australis extractive grains |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109125378A (en) * | 2017-06-19 | 2019-01-04 | 湖南联丰生物科技有限公司 | It is a kind of to utilize herbal medicine made of acalypha copperleaf extract |
| CN112057491A (en) * | 2020-10-15 | 2020-12-11 | 西南科技大学 | Application of copperleaf herb water extract in preparation of weight-losing and lipid-lowering medicines or weight-losing and lipid-lowering health-care products |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20020029184A (en) * | 2000-10-12 | 2002-04-18 | 성재갑 | Cosmetic composition containing Acalypha australis L. extracts and Pterocarya stenoptera DC extracts |
| CN1682874A (en) * | 2005-03-15 | 2005-10-19 | 中国人民解放军第二军医大学 | Use of acalypha copperleaf water extract in preparing medicine for treating chronic ulcerative colitis |
| CN101537037A (en) * | 2008-03-21 | 2009-09-23 | 福州海王金象中药制药有限公司 | Amaranth berberine tablet and preparation method thereof |
| CN102100305A (en) * | 2010-12-30 | 2011-06-22 | 镇江天和生物技术有限公司 | Preparation method of humifuse euphorbia extract particle |
| CN102614349A (en) * | 2012-04-19 | 2012-08-01 | 西南大学 | Traditional Chinese medical composition for prevention and treatment of A type clostridiosis welchii, extract, preparation and preparation method and application |
-
2013
- 2013-08-08 CN CN2013103429743A patent/CN103444995A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20020029184A (en) * | 2000-10-12 | 2002-04-18 | 성재갑 | Cosmetic composition containing Acalypha australis L. extracts and Pterocarya stenoptera DC extracts |
| CN1682874A (en) * | 2005-03-15 | 2005-10-19 | 中国人民解放军第二军医大学 | Use of acalypha copperleaf water extract in preparing medicine for treating chronic ulcerative colitis |
| CN101537037A (en) * | 2008-03-21 | 2009-09-23 | 福州海王金象中药制药有限公司 | Amaranth berberine tablet and preparation method thereof |
| CN102100305A (en) * | 2010-12-30 | 2011-06-22 | 镇江天和生物技术有限公司 | Preparation method of humifuse euphorbia extract particle |
| CN102614349A (en) * | 2012-04-19 | 2012-08-01 | 西南大学 | Traditional Chinese medical composition for prevention and treatment of A type clostridiosis welchii, extract, preparation and preparation method and application |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109125378A (en) * | 2017-06-19 | 2019-01-04 | 湖南联丰生物科技有限公司 | It is a kind of to utilize herbal medicine made of acalypha copperleaf extract |
| CN112057491A (en) * | 2020-10-15 | 2020-12-11 | 西南科技大学 | Application of copperleaf herb water extract in preparation of weight-losing and lipid-lowering medicines or weight-losing and lipid-lowering health-care products |
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Application publication date: 20131218 |