CN103417399A - Toothpaste with fluoride - Google Patents
Toothpaste with fluoride Download PDFInfo
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- CN103417399A CN103417399A CN2013103745219A CN201310374521A CN103417399A CN 103417399 A CN103417399 A CN 103417399A CN 2013103745219 A CN2013103745219 A CN 2013103745219A CN 201310374521 A CN201310374521 A CN 201310374521A CN 103417399 A CN103417399 A CN 103417399A
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- fluoride
- toothpaste
- sodium
- whitening agent
- sorbitol
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Abstract
The invention relates to toothpaste with fluoride. The toothpaste with the fluoride comprises, by weight, 0.6-1.2% of sodium monofluorophosphate, 0.1-0.3% of sodium fluoride, 45-55% of calcium carbonate, 10-14% of glycerinum, 16-20% of sorbitol, 1-2% of guar gum, 0.2-0.6% of magnesium hydrogen phosphate, 1.8-2.6% of lauroyl amphoteric base di-propionic acid disodium and the balance water. The toothpaste with the fluoride is abundant in foam, the anti-acid capability of the teeth can be improved, and therefore the toothpaste with the fluoride can play a role of preventing the decayed teeth.
Description
Technical field
The present invention relates to a kind of toothpaste, be specifically related to a kind of toothpaste with fluoride.
Background technology
Toothpaste is to be used from cleaning teeth with toothbrush one, and the protection oral hygiene, to a kind of daily necessities of human-body safety.Along with the raising of people's living standard, to the also progressively raising of quality requirement of toothpaste.At aspect of performance General Requirements toothpaste: (1) can remove the thin film of dental surface and bacterial plaque and not damage enamel and dentin; (2) there is good cleaning oral cavity and effect on every side thereof; (3) avirulence, non-stimulated to oral mucosa; (4) comfortable fragrance and taste are arranged, cool and sweet-smelling sensation is arranged after use.
Summary of the invention
For above shortcomings in prior art, technical problem to be solved by this invention is to provide a kind of toothpaste with fluoride.
The present invention seeks to be achieved through the following technical solutions:
A kind of toothpaste with fluoride, by following compositions in weight percentage, formed: the 0.6-1.2% sodium monofluorophosphate, the 0.1-0.3% sodium fluoride, the 45-55% calcium carbonate, 10-14% glycerol, 16-20% sorbitol, the 1-2% guar gum, the 0.2-0.6% magnesium hydrogen phosphate, 1.8-2.6% lauroyl both sexes base disodium beclomethasone, surplus is water.
Preferably,
A kind of toothpaste with fluoride, by following compositions in weight percentage, formed: the 0.6-1.2% sodium monofluorophosphate, the 0.1-0.3% sodium fluoride, 45-55% calcium carbonate, 10-14% glycerol, the 16-20% sorbitol, the 1-2% guar gum, 0.2-0.6% magnesium hydrogen phosphate, 1.8-2.6% lauroyl both sexes base disodium beclomethasone, the 1-3% whitening agent, surplus is water.
Described whitening agent is a kind of or its mixture in sodium phytate, aloin, glycyrrhizin and glucoseoxidase.
Best, described whitening agent consists of by weight following component: 40-60 part sodium phytate, 10-20 part aloin, 10-20 part glycyrrhizin and 15-25 part glucoseoxidase.
In the present invention,
Sodium phytate, English name: Sodium phytate, CAS accession number: 14306-25-3.
Aloin, English name: Aloin, CAS accession number: 5133-19-7.
Glycyrrhizin, English name: Glycyrrhizic acid, CAS accession number: 1405-86-3.
Glucoseoxidase, No. CAS: 9001-37-0, name of commodity in English: EC1.1.3.4, EINECS:232-601-0.
Compared with prior art, toothpaste with fluoride foam of the present invention is abundant, can improve the capacity antacid of tooth, thereby play the effect of preventing and treating dental caries.
The specific embodiment
Embodiment 1
A kind of toothpaste with fluoride is comprised of following compositions in weight percentage: 0.9% sodium monofluorophosphate, 0.2% sodium fluoride, 50% calcium carbonate, 12% glycerol, 18% sorbitol, 1.5% guar gum, 0.4% magnesium hydrogen phosphate, 2.2% lauroyl both sexes base disodium beclomethasone, 2% whitening agent, surplus is water.
Described whitening agent consists of by weight following component: 50 parts of sodium phytates, 15 parts of aloins, 15 parts of glycyrrhizins and 20 parts of glucoseoxidases.
Toothpaste with fluoride of the present invention can adopt the conventional method preparation of this area fully, as " detergent compositions workshop manual ", (Xu Baocai etc. write, Chemical Industry Press, chemistry and applied chemistry publishing centre, January in 2006 the 1st edition) the disclosed toothpaste production technology of 594-597 page is prepared.Concrete, the preparation method of the present embodiment toothpaste with fluoride is: after the above-mentioned raw materials component is weighed, disperse in pre-dispersed still, mix, open cream still vacuum pump processed and suck above-mentioned liquid material, then open scraper, agitator and colloid mill, close colloid mill, agitator and scraper successively after 50 minutes, vacuum breaker, obtain toothpaste with fluoride.
Obviously, the preparation method of toothpaste is prior art in the present invention, does not have special character, and main improvement of the present invention just is the difference of formula.
Embodiment 2
A kind of toothpaste with fluoride is comprised of following compositions in weight percentage: 0.9% sodium monofluorophosphate, 0.2% sodium fluoride, 50% calcium carbonate, 12% glycerol, 18% sorbitol, 1.5% guar gum, 0.4% magnesium hydrogen phosphate, 2.2% lauroyl both sexes base disodium beclomethasone, 2% whitening agent, surplus is water.
Described whitening agent consists of by weight following component: 50 parts of sodium phytates, 15 parts of aloins and 20 parts of glucoseoxidases.
According to the preparation method of embodiment 1, obtain the toothpaste with fluoride of embodiment 2.
Embodiment 3
A kind of toothpaste with fluoride is comprised of following compositions in weight percentage: 0.9% sodium monofluorophosphate, 0.2% sodium fluoride, 50% calcium carbonate, 12% glycerol, 18% sorbitol, 1.5% guar gum, 0.4% magnesium hydrogen phosphate, 2.2% lauroyl both sexes base disodium beclomethasone, 2% whitening agent, surplus is water.
Described whitening agent consists of by weight following component: 50 parts of sodium phytates, 15 parts of glycyrrhizins and 20 parts of glucoseoxidases.
According to the preparation method of embodiment 1, obtain the toothpaste with fluoride of embodiment 3.
Embodiment 4
A kind of toothpaste with fluoride is comprised of following compositions in weight percentage: 0.9% sodium monofluorophosphate, 0.2% sodium fluoride, 50% calcium carbonate, 12% glycerol, 18% sorbitol, 1.5% guar gum, 0.4% magnesium hydrogen phosphate, 2.2% lauroyl both sexes base disodium beclomethasone, 2% whitening agent, surplus is water.
Described whitening agent consists of by weight following component: 50 parts of sodium phytates, 15 parts of aloins and 15 parts of glycyrrhizins.
According to the preparation method of embodiment 1, obtain the toothpaste with fluoride of embodiment 4.
Embodiment 5
A kind of toothpaste with fluoride is comprised of following compositions in weight percentage: 0.9% sodium monofluorophosphate, 0.2% sodium fluoride, 50% calcium carbonate, 12% glycerol, 18% sorbitol, 1.5% guar gum, 0.4% magnesium hydrogen phosphate, 2.2% lauroyl both sexes base disodium beclomethasone, 2% whitening agent, surplus is water.
Described whitening agent consists of by weight following component: 15 parts of aloins, 15 parts of glycyrrhizins and 20 parts of glucoseoxidases.
According to the preparation method of embodiment 1, obtain the toothpaste with fluoride of embodiment 5.
Embodiment 6
A kind of toothpaste with fluoride is comprised of following compositions in weight percentage: 0.9% sodium monofluorophosphate, and 0.2% sodium fluoride, 50% calcium carbonate, 12% glycerol, 18% sorbitol, 1.5% guar gum, 0.4% magnesium hydrogen phosphate, 2.2% lauroyl both sexes base disodium beclomethasone, surplus is water.
According to the preparation method of embodiment 1, obtain the toothpaste with fluoride of embodiment 6.
Test case
48 adult men and women are divided into to 6 groups, use embodiment 1-5 toothpaste, every day, each was brushed once sooner or later, to reaching the mottle index LSI of use after 3 months continuously before using, tested respectively, method of testing and scoring rule are permitted first 5th～6 pages of 1.4.1 of master thesis " a kind of clinical efficacy evaluation study of novel whitening toothpaste " of son referring to Shanghai Communications University.
The LSI scoring method, concrete scoring rule is as follows:
0 minute-without mottle, exist;
1 minute-mottle size is no more than 1/3 of facing; Degree is slight mottle (yellow or yellowish-brown);
2 minutes-mottle size is no more than 2/3 of facing; Degree is moderate mottle (moderate brown);
3 minutes-mottle size is greater than 2/3 of facing; Degree is severe mottle (dark-brown or black).
LSI value after the statistics experimenter uses front LSI value and uses March, LSI meansigma methods after calculating the front LSI meansigma methods of use and using March, then calculate mottle index LSI rate of descent, the results are shown in Table 1.
Table 1: mottle index LSI test chart
| ? | Mottle index LSI rate of descent, % |
| Embodiment 1 | 27.6 |
| Embodiment 2 | 26.2 |
| Embodiment 3 | 26.4 |
| Embodiment 4 | 24.1 |
| Embodiment 5 | 22.2 |
| Embodiment 6 | 12.7 |
Mottle index LSI rate of descent (%)=[LSI meansigma methods before using-uses is the LSI meansigma methods after March]/use front LSI meansigma methods * 100%.
As seen from the data in Table 1, using embodiment 1-5 toothpaste after 3 months, the obvious decline of LSI value, toothpaste of the present invention has whitening effect preferably.
Claims (4)
1. a toothpaste with fluoride, it is characterized in that, by following compositions in weight percentage, formed: 0.6-1.2% sodium monofluorophosphate, 0.1-0.3% sodium fluoride, 45-55% calcium carbonate, 10-14% glycerol, the 16-20% sorbitol, 1-2% guar gum, 0.2-0.6% magnesium hydrogen phosphate, 1.8-2.6% lauroyl both sexes base disodium beclomethasone, surplus is water.
2. a toothpaste with fluoride, it is characterized in that, formed by following compositions in weight percentage: 0.6-1.2% sodium monofluorophosphate, 0.1-0.3% sodium fluoride, the 45-55% calcium carbonate, 10-14% glycerol, 16-20% sorbitol, 1-2% guar gum, the 0.2-0.6% magnesium hydrogen phosphate, 1.8-2.6% lauroyl both sexes base disodium beclomethasone, the 1-3% whitening agent, surplus is water.
3. toothpaste with fluoride as claimed in claim 2, it is characterized in that: described whitening agent is a kind of or its mixture in sodium phytate, aloin, glycyrrhizin and glucoseoxidase.
4. toothpaste with fluoride as claimed in claim 3, is characterized in that, described whitening agent consists of by weight following component: 40-60 part sodium phytate, 10-20 part aloin, 10-20 part glycyrrhizin and 15-25 part glucoseoxidase.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310374521.9A CN103417399B (en) | 2013-08-24 | 2013-08-24 | Toothpaste with fluoride |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310374521.9A CN103417399B (en) | 2013-08-24 | 2013-08-24 | Toothpaste with fluoride |
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| Publication Number | Publication Date |
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| CN103417399A true CN103417399A (en) | 2013-12-04 |
| CN103417399B CN103417399B (en) | 2016-05-11 |
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| CN201310374521.9A Active CN103417399B (en) | 2013-08-24 | 2013-08-24 | Toothpaste with fluoride |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105878120A (en) * | 2016-05-25 | 2016-08-24 | 美晨集团股份有限公司 | Calcium carbonate type stain-removing and anti-carious toothpaste and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1633968A (en) * | 2004-11-15 | 2005-07-06 | 杨毅男 | Common and functional form solid toothpaste |
| CN101264046A (en) * | 2008-05-07 | 2008-09-17 | 美晨集团股份有限公司 | Toothpaste containing enzyme and preparation thereof |
-
2013
- 2013-08-24 CN CN201310374521.9A patent/CN103417399B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1633968A (en) * | 2004-11-15 | 2005-07-06 | 杨毅男 | Common and functional form solid toothpaste |
| CN101264046A (en) * | 2008-05-07 | 2008-09-17 | 美晨集团股份有限公司 | Toothpaste containing enzyme and preparation thereof |
Non-Patent Citations (1)
| Title |
|---|
| 郭茂祥: "芦荟牙膏的生产与功效", 《牙膏工业》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105878120A (en) * | 2016-05-25 | 2016-08-24 | 美晨集团股份有限公司 | Calcium carbonate type stain-removing and anti-carious toothpaste and preparation method thereof |
| CN105878120B (en) * | 2016-05-25 | 2018-12-25 | 美晨集团股份有限公司 | A kind of calcium carbonate type removes stain anticarious tooth paste and preparation method thereof |
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| Publication number | Publication date |
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| CN103417399B (en) | 2016-05-11 |
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Effective date of registration: 20190102 Address after: 324000 Shuanggang Street, Kecheng District, Quzhou City, Zhejiang Province, No. 10 Shuguang Road Patentee after: Zhejiang Taikang Biological Technology Co., Ltd. Address before: 201107 T159 twenty-second, 1-30 Lane 88, min Bei Road, Minhang District, Shanghai. Patentee before: Shanghai Fangmu Fine Chemical Co., Ltd. |
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