CN103393903A - Medicament for treating leucoderma - Google Patents

Abstract

A medicament for treating leucoderma is prepared by taking traditional Chinese medicines as bulk drugs, and the bulk drugs comprise in parts by weight: 20-35 parts of radix astragali, 28-35 parts of radix polygoni multiflori preparata, 10-15 parts of eclipta alba, 10-18 parts of semen cuscutae, 5-15 parts of psoralea corylifolia, 5-15 parts of semen astragali complanati, 5-10 aprts of Chinese angelica, 8-15 parts of white peony root, 8-15 parts of lithospermum, 6-10 parts of salvia miltiorrhiza, 8-12 parts of dahurian angelica root, 8-15 parts of rhizoma paridis and 35-45 parts of fried dictamnus dasycarpus turcz. The medicament can be prepared into any pharmaceutical dosage form such as tablets, pills, powder, capsules and the like. By adjusting somatic function of patients and promoting blood circulation, the medicament of the invention helps to restore damaged skin and treating leukoderma, and has no toxic and side effect by employing pure natural traditional Chinese medicines.

Description

A kind ofly treat leukodermic medicine

Technical field

The present invention relates to a kind of medicine, be specifically related to a kind of leukodermic Chinese medicine preparation for the treatment of.

Background technology

Vitiligo is a kind of common multiple pigmented dermatosis, and this disease forms white macula as feature take local or general property depigmentation, is a kind of acquired, and skin pigment takes off and loses the white patch that forms.

For a long time, vitiligo is perplexing extensive patients as the U.S. dermatoses of a kind of common damage, if treatment or malpractice may spread all over whole body not in time.Vitiligo is an easily diagnosis, but be not the disease that is easy to treat relatively, a lot of people have adopted various external used medicines, or the therapy of physics, all can not effectively treat, and, the western medicine vitiligo also can take effect, but side effect is large, is difficult to control the state of an illness, and relapse rate is more than 95%.

Summary of the invention

For above-mentioned situation, the purpose of this invention is to provide a kind of leukodermic medicine for the treatment of, by regulating patient's physical function, blood circulation promoting, thus repair damaged skin treatment leukoderma, adopt the treatment by Chinese herbs of pure natural, have no side effect.

Medicine of the present invention is that the Chinese medicine by following parts by weight is that crude drug prepares:

Radix Astragali 20-35 Radix Polygoni Multiflori Preparata 28-35 Herba Ecliptae 10-15

Semen Cuscutae 10-18 Fructus Psoraleae 5-15 Semen Astragali Complanati 5-15

Radix Angelicae Sinensis 5-10 Radix Paeoniae Alba 8-15 Radix Arnebiae (Radix Lithospermi) 8-15

Radix Salviae Miltiorrhizae 6-10 Radix Angelicae Dahuricae 8-12 Rhizoma Paridis 8-15

Fry Cortex Dictamni 35-45.

Preferably, medicine of the present invention is that the Chinese medicine by following parts by weight is that crude drug prepares:

The Radix Astragali 30 Radix Polygoni Multiflori Preparata 30 Herba Ecliptaes 15

Semen Cuscutae 15 Fructus Psoraleae 10 Semen Astragali Complanatis 10

Radix Angelicae Sinensis 10 Radix Paeoniae Alba 10 Radix Arnebiae (Radix Lithospermi)s 10

Radix Salviae Miltiorrhizae 9 Radix Angelicae Dahuricae 10 Rhizoma Paridis 10

Fry Cortex Dictamni 40.

Said medicine can be made to any dosage form on pharmaceutics, as tablet, pill, powder, capsule etc., the preferred dosage form of the present invention is pill.

The concrete preparation method of pill of the present invention is as follows:

Described medicine is added to container together, add water logging and do not have medicine, decocted 30 minutes, filter, decoct three times, merging filtrate, be dried and crushed into powder, is prepared into medicine activity component, adds the Mel that can make active component be mixed into ball to make pill.

The traditional Chinese medical science thinks that the leukodermic basic way for the treatment of is blood circulation promoting and blood stasis dispelling, dispelling wind and removing obstruction in the collateral, Radix Astragali tonifying Qi and lifting yang in prescription of the present invention, and strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promote the production of body fluid and nourish blood, the stagnant blood stasis dispelling of row, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation; The Radix Polygoni Multiflori Preparata invigorating the liver and kidney, benefiting essence-blood, black beard and hair, bone and muscle strengthening, change turbid blood fat reducing; Herba Ecliptae removing heat from blood, hemostasis, nourishing the liver and kidney, heat-clearing and toxic substances removing; The Semen Cuscutae liver and kidney tonifying, the controlling nocturnal emission with astringent drugs reducing urination; The Fructus Psoraleae warming the kidney to activate YANG, helping inspiration to relieve asthma, warming spleen and stopping diarrha; The Semen Astragali Complanati reinforcing the kidney and supporting YANG, controlling nocturnal emission with astringent drugs reducing urination, nourishing the liver to improve visual acuity; Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation; Radix Paeoniae Alba nourishing blood for regulating menstruation, astringing YIN to stop sweating, easing the affected liver to relieve pain, suppressing liver-YANG; The Radix Arnebiae (Radix Lithospermi) clearing away heat and cooling blood, promoting blood circulation and detoxication, rash speckle removing; The Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, the relieving restlessness that clears away heart-fire, removing heat from blood eliminating carbuncle; The Radix Angelicae Dahuricae cold expelling that induces sweat, wind-expelling pain-stopping, a surname's clearing the nasal passage, dampness leukorrhagia stopping, detumescence and apocenosis; The Rhizoma Paridis heat-clearing and toxic substances removing, reducing swelling and alleviating pain, cool liver arresting convulsion; Fry the Cortex Dictamni heat clearing and damp drying, the detoxifcation of dispeling the wind.All medicines share promoting blood circulation and detoxication, dissolving stasis and dispelling spots, expelling wind and replenishing blood.

For further investigating clinical efficacy and the safety of medicine of the present invention, select 68 routine patients with vitiligo to carry out clinical observation to the curative effect of bolus of drug of the present invention.

Patient's data: male 36 examples in 68 routine patients, female's 32 examples, age 18-55 year, the course of disease 3 months-6 years.

Diagnostic criteria: on skin, agnogenic depigmentation speckle is shown in perusal, and form is not of uniform size, and the patch boundary line is clear or unclear, outside the depigmentation speckle, has pigment to deepen in week, without obvious subjective symptoms.

The Excluded cases standard:

The depigmentation of leaving over after some deflorescence, nevus anemicus, albinism and other syndromes cause white macula, senile white macula, sun tan white macula etc.;

Complete and the serious primary disease such as cardiovascular, liver, kidney and hemopoietic system, psychotic arranged;

Age is at under-18s or over-65s, anemia of pregnant woman or women breast-feeding their children, those who are allergic to this drug;

In process of the test, take or outside be coated with the similar drugs person;

Do not meet inclusive criteria, not medication in accordance with regulations, can't judge that curative effect or data are not congruent to affect the treatment or safety judgement person.

Therapeutic Method: the patient takes the pill of medicine of the present invention, each ball sooner or later, morning, light salt brine took, evening warm water delivery service.

Curative effect determinate standard

Recovery from illness: white macula disappears fully, and histopathology of skin checks normal;

Produce effects: white macula disappears more than 50%, and white macula disappearance portion of tissue pathological examination is normal;

Effectively: white macula disappearance person accounts for the 20%-50% of former white macula area, or in white macula, sees have than the polychrom island;

Invalid: unchanged or white macula expansion before and after treatment.

Therapeutic outcome: the patients with vitiligo medication is after one month, and development speed slows down; After two months, the state of an illness is controlled in medication; Took medicine three months to six months, the pigmentation spots that the white macula place differs in size as seen; After medication 1 year, the small size white macula disappears.In 68 routine patients, recovery from illness 32 examples, cure rate 47.1%; Produce effects 15 examples, obvious effective rate 22.1%; Effective 9 examples, effective percentage 13.2%, total effective rate 82.4%; Invalid 12 examples, inefficiency 17.6%.Through following up a case by regular visits to 3-5 month, curative effect is sure, without recurrence.

The specific embodiment

Embodiment 1

Get Radix Astragali 20g, Radix Polygoni Multiflori Preparata 30 g, Herba Ecliptae 12 g, Semen Cuscutae 18 g, Fructus Psoraleae 10 g, Semen Astragali Complanati 10 g, Radix Angelicae Sinensis 10 g, the Radix Paeoniae Alba 8 g, Radix Arnebiae (Radix Lithospermi) 10 g, Radix Salviae Miltiorrhizae 6 g, the Radix Angelicae Dahuricae 10 g, Rhizoma Paridis 15 g, fry Cortex Dictamni 40g;

Described medicine is added to container together, add water logging and do not have medicine, decocted 30 minutes, filter, decoct three times, merging filtrate, be dried and crushed into powder, is prepared into medicine activity component, adds the Mel that can make active component be mixed into ball to make pill.

Embodiment 2

Get Radix Astragali 35g, Radix Polygoni Multiflori Preparata 28 g, Herba Ecliptae 11g, Semen Cuscutae 10g, Fructus Psoraleae 8 g, Semen Astragali Complanati 5 g, Radix Angelicae Sinensis 8 g, Radix Paeoniae Alba 15g, Radix Arnebiae (Radix Lithospermi) 12g, Radix Salviae Miltiorrhizae 8 g, the Radix Angelicae Dahuricae 12 g, Rhizoma Paridis 10 g, fry Cortex Dictamni 45g;

Described medicine is added to container together, add water logging and do not have medicine, decocted 30 minutes, filter, decoct three times, merging filtrate, be dried and crushed into powder, is prepared into medicine activity component, adds the Mel that can make active component be mixed into ball to make pill.

Claims (2)

1. treat leukodermic medicine for one kind, it is characterized in that the Chinese medicine by following parts by weight is that crude drug prepares:

Radix Astragali 20-35 Radix Polygoni Multiflori Preparata 28-35 Herba Ecliptae 10-15

Semen Cuscutae 10-18 Fructus Psoraleae 5-15 Semen Astragali Complanati 5-15

Radix Angelicae Sinensis 5-10 Radix Paeoniae Alba 8-15 Radix Arnebiae (Radix Lithospermi) 8-15

Radix Salviae Miltiorrhizae 6-10 Radix Angelicae Dahuricae 8-12 Rhizoma Paridis 8-15

Fry Cortex Dictamni 35-45.

2. the leukodermic medicine for the treatment of according to claim 1 it is characterized in that the Chinese medicine by following parts by weight is that crude drug prepares:

The Radix Astragali 30 Radix Polygoni Multiflori Preparata 30 Herba Ecliptaes 15

Semen Cuscutae 15 Fructus Psoraleae 10 Semen Astragali Complanatis 10

Radix Angelicae Sinensis 10 Radix Paeoniae Alba 10 Radix Arnebiae (Radix Lithospermi)s 10

Radix Salviae Miltiorrhizae 9 Radix Angelicae Dahuricae 10 Rhizoma Paridis 10

Fry Cortex Dictamni 40.