CN103393799B - A kind of Chinese medicine composition for the treatment of acquired immune deficiency syndrome (AIDS) and preparation method thereof - Google Patents
A kind of Chinese medicine composition for the treatment of acquired immune deficiency syndrome (AIDS) and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine composition for the treatment of acquired immune deficiency syndrome (AIDS); it is formulated by the raw material of Chinese medicine of following weight, Rhizoma Atractylodis 3500 grams, the Radix Aucklandiae 3500 grams, Flos Caryophylli 2500 grams, Cortex Mori 4000 grams, Radix Glycyrrhizae 4000 grams, Calculus Bovis 300 grams, Venenum Bufonis 50 grams, Realgar 10 grams, 10 grams, Cinnabaris, Calomelas 10 grams, Herba Menthae 2000 grams, 10 grams, Moschus, Fructus Crataegi 5000 grams, Herba Paederiae 2500 grams, Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 2500 grams.Advantage of the present invention is: treatment acquired immune deficiency syndrome (AIDS) effective percentage 96%, cure rate 70%.
Description
Technical field
Medicine of the present invention belongs to pure technical field of Chinese medicines, specifically a kind of Chinese medicine composition for the treatment of acquired immune deficiency syndrome (AIDS) and preparation method thereof.
Background technology
As acquired immune deficiency syndrome (AIDS) in the last few years, rapidly, the health of harm people was national governments and medical circles' very headache in development, and the infection of refractory is sick, does not also have very feasible treatment and prevention and controls up till now.Twentieth century claims acquired immune deficiency syndrome (AIDS) to be Bubonic plague, is also called as the pestilence of God's punishment.At present, the traditional Chinese medical science is all that to treat the complication caused due to HIV (human immunodeficiency virus) be master, instead of from being set about poison of curing the disease at all, can only taking stopgap measures and can not effect a permanent cure, so effectively can not effect a radical cure acquired immune deficiency syndrome (AIDS).Such as, State Intellectual Property Office is number of patent application " 011449519 " disclosed on 07 09th, 2003, and denomination of invention " Chinese medicine composition for the treatment of acquired immune deficiency syndrome (AIDS) and preparation method thereof " treatment acquired immune deficiency syndrome (AIDS) has cures slowly, the shortcoming that cure rate is low.The clinical cardinal symptom of acquired immune deficiency syndrome (AIDS) is: heating, pharyngalgia, night sweat, nausea,vomiting,diarrhea, erythra, arthralgia, lymphadenectasis, Lymph nodes diameter >=1cm, without tenderness, without adhesion, and more than 3 months persistent period; Lose weight more than 10%, hypomnesis, indifferent, the personality change of spirit, headache, epilepsy and dementia etc.HIV-RNA and P24 antigen can be detected in blood.Its main cause of falling ill: insecurity life cycle, intravenous injection drug use history, input the blood or blood product, children that HIV antibody positive is given birth to or occupational exposure history etc. that detect without ANTI-HIV DRUGS.
Summary of the invention
Object of the present invention is just the pure Chinese medicine providing a kind of energy treatment of AIDS.
Technical scheme of the present invention realizes like this; a kind of Chinese medicine composition for the treatment of acquired immune deficiency syndrome (AIDS); it is characterized in that: it is formulated by the raw material of Chinese medicine of following weight, Rhizoma Atractylodis 3500 grams, the Radix Aucklandiae 3500 grams, Flos Caryophylli 2500 grams, Cortex Mori 4000 grams, Radix Glycyrrhizae 4000 grams, Calculus Bovis 300 grams, Venenum Bufonis 50 grams, Realgar 10 grams, 10 grams, Cinnabaris, Calomelas 10 grams, Herba Menthae 2000 grams, 10 grams, Moschus, Fructus Crataegi 5000 grams, Herba Paederiae 2500 grams, Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 2500 grams.
The preparation method of medicine of the present invention is: be first placed in marmite by Rhizoma Atractylodis 3500 grams, the Radix Aucklandiae 3500 grams, Flos Caryophylli 2500 grams, Cortex Mori 4000 grams, Radix Glycyrrhizae 4000 grams, Fructus Crataegi 5000 grams, Herba Paederiae 2500 grams, Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 2500 grams, add water and cross the high 5 centimetres of immersions of powder 20 minutes, water is outwelled, adding water again, to cross powder high 5 centimetres, endure out with high heat, then endure 15 minutes with moderate heat, rapidly Herba Menthae 2000 grams is put in the marmite endured, use slow fire instead and endure 30 minutes, take out medicinal liquid, and then adding water, to cross powder high 5 centimetres, endures out with high heat, use slow fire instead and endure 25 minutes, take out medicinal liquid, and then adding water, to cross powder high 5 centimetres, endures out with high heat, use moderate heat instead 10 minutes, then endure 20 minutes with slow fire, take out medicinal liquid, then first time, for the second time, third time, the medicinal liquid one piece endured poured the interior moderate heat of marmite into when enduring to magma, using slow fire instead endures to when playing vesicle, rapidly with 100 grams of Chinese liquor, the Venenum Bufonis 50 grams that Venenum Bufonis 50 digests out being put in marmite in advance, use urgent greatly decocting medicinal herbs instead and remove fire rapidly when liquid plays bulla, ointment, then ointment is poured out and to dry in the shade or by oven for drying, the temperature of baking oven is between 45-55 DEG C, then by dry ointment and Calculus Bovis 300 grams, Realgar 10 grams, 10 grams, Cinnabaris, Calomelas 10 grams is placed on one piece and pulverized 300 mesh sieves, then medicated powder and 10 grams, Moschus are placed on one piece of mix homogeneously, make capsule, every capsules fills 0.3 gram.Each serving 0.3 gram, each serving 1, take 2 day, early, after supper under warm water clothes.
Medicine of the present invention has inhibiting HIV, Yin Yang balancing, regulates function, effect of promoting digestion and removing stagnation.
Medicine of the present invention is applicable to treat acquired immune deficiency syndrome (AIDS), cardinal symptom: heating, pharyngalgia, night sweat, nausea,vomiting,diarrhea, erythra, arthralgia, lymphadenectasis, Lymph nodes diameter >=1cm, without tenderness, without adhesion, hypomnesis, spirit are indifferent, headache, epilepsy and dementia.Blood test, can detect HIV-RNA and P24 antigen.
Treat the course for the treatment of: within 30 days, be 1 course for the treatment of, the lighter, 2-5 the course for the treatment of can cure, severe one, and 5-12 the course for the treatment of can cure.
Therapeutic effect: effective percentage 96%, cure rate 70%.
The mechanism of medicine of the present invention is as follows:
Rhizoma Atractylodis: acrid in the mouth, hardship, warm in nature.Return spleen, stomach, Liver Channel.Have drying damp and strengthening spleen, wind-damp dispelling, effect of improving eyesight.Modern medicine study, has antivirus action.Reference, " Chinese medicine voluminous dictionary, Nanjing University of Traditional Chinese Medicine writes, the second edition, Shanghai science tech publishing house, and the 18th printing February in 2012, is shown in 1482-1485 page "
The Radix Aucklandiae: acrid in the mouth, hardship, warm in nature.Return spleen, stomach, liver, lung meridian.There are promoting the circulation of QI to relieve pain, effect of intestinal stasis relieving in tune.(the same, to see 478-480 page)
Flos Caryophylli: acrid in the mouth, warm in nature.Nontoxic.Return spleen, stomach, kidney channel.There is warming middle-JIAO, sending down the abnormal ascending QI, effect of warming the kidney.(the same, to see 14-15 page)
Venenum Bufonis: acrid in the mouth, warm in nature.Poisonous.GUIXIN warp.Have reducing swelling and alleviating pain, dirty effect is warded off in removing toxic substances.(the same, to see 3833-3834 page) modern medicine study, has shock, improves immunity, antitumor action.
Calculus Bovis: bitter in the mouth, sweet, cool in nature.GUIXIN, Liver Channel.There is the cool liver that clears away heart-fire, eliminate phlegm for resuscitation, effect of heat-clearing and toxic substances removing.(the same, to see 565-566 page)
Realgar: acrid in the mouth, hardship, warm in nature.Poisonous.Return liver, stomach warp.There is effect of removing toxic substances, parasite killing, dampness, the expectorant that dispels the wind.(the same, to see 3263-3264 page) modern medicine study, has antitumor, improves immunization.
Cinnabaris: sweet in the mouth, cool in nature.Poisonous.GUIXIN warp.There is arresting convulsion of calming the nerves, improving eyesight, effect of removing toxic substances.(the same, to see 1233-1234 page)
Cortex Mori: sweet in the mouth, pungent, cold in nature.Return lung, spleen channel.There is depressed lung-energy dispersing, effect of inducing diuresis to remove edema.(the same, to see 2789-2787 page) modern medicine study, has inhibitory action to HIV (human immunodeficiency virus).
Radix Glycyrrhizae: sweet in the mouth, property is put down.Return spleen, stomach, the heart, lung meridian.Have and middle emergency, lung moistening, removing toxic substances, effect of coordinating the actions of various ingredients in a prescription.(the same, to see 788-792 page) modern medicine study, has inhibitory action to HIV (human immunodeficiency virus).
Calomelas: acrid in the mouth, cold in nature.Poisonous.Return liver, kidney, large intestine channel.There is external counteracting toxic substances, putrefaction removing, parasite killing, antipruritic; Take orally and eliminate the phlegm, relieve oedema or abdominal distension through diuresis or purgation, effect of relieving constipation.(the same, to see 2300-2301 page)
Fructus Crataegi: sour in the mouth, sweet, slightly warm in nature.Return spleen, stomach, Liver Channel.There is promoting digestion and invigorating the stomach, effect of circulation of qi promoting dissipating blood stasis.(the same, to see 225-226 page) modern medicine study, can improve immunocompetence, anti-cancer.
Herba Paederiae: sweet in the mouth, micro-hardship, property is put down.There is clearing away summer-heat and eliminating dampness, removing food stagnancy, effect of removing toxic substances.(the same, to see 1698-1699 page)
Herba Desmodii Triquetri (Herba Tadehagi Triquetri): bitter in the mouth, puckery, cool in nature.There is heat-clearing and toxic substances removing, effect of diuretic removing food stagnancy.(the same, to see 3203-3204 page)
Herba Menthae: acrid in the mouth, cool in nature.Return lung, Liver Channel.There is dispelling wind-heat, the clear sharp head, sore-throat relieving, rash, effect of dispersing the stagnated live-QI to relieve the stagnation of QI.(the same, to see 3729-3731 page)
With Rhizoma Atractylodis, the Radix Aucklandiae, Flos Caryophylli, Cortex Mori, Radix Glycyrrhizae, Calculus Bovis, Venenum Bufonis, Realgar, Cinnabaris, Calomelas, the copying of Herba Menthae inhibiting HIV in the present invention, Save and restore immunologic function; The effect copied of Rhizoma Atractylodis, the Radix Aucklandiae, Flos Caryophylli, Cortex Mori, Radix Glycyrrhizae, Calculus Bovis, Venenum Bufonis, Realgar, Cinnabaris, Calomelas, Herba Menthae inhibiting HIV is strengthened with Moschus; Help digestion with Fructus Crataegi, Herba Paederiae, Herba Desmodii Triquetri (Herba Tadehagi Triquetri) spleen benefiting and stimulating the appetite, delivery efficacy of a drug serious disease institute, all medicines are harmonious, and bring out the best in each other, and gather inhibiting HIV altogether, improve immunocompetence, effect of promoting digestion and removing stagnation.
Medical circles think that acquired immune deficiency syndrome (AIDS) is fallen ill main cause: have insecurity life cycle, intravenous injection drug use history, to input the aids infection such as blood or blood product, children that HIV antibody positive is given birth to detected without ANTI-HIV DRUGS malicious and obtain, reason HIV (human immunodeficiency virus) infringement body, make each visceral dysfunction, therefore occur: heating, pharyngalgia, night sweat, nausea,vomiting,diarrhea, erythra, arthralgia, lymphadenectasis, Lymph nodes diameter >=1cm, without tenderness, without adhesion, more than 3 months persistent period; Lose weight more than 10%, hypomnesis, indifferent, the personality change of spirit, headache, epilepsy and dementia.Control suitable anti AIDS virus, regulate function, Yin Yang balancing, spleen benefiting and stimulating the appetite, can encroach on body by inhibiting HIV, equilibrium between yin and yang, make each function recover normal, therefore heating, pharyngalgia, night sweat, nausea,vomiting,diarrhea, erythra, arthralgia, lymphadenectasis can be eliminated rapidly, Lymph nodes diameter >=1cm, the symptoms such as hypomnesis, spirit are indifferent, headache, epilepsy and dementia, rapid treatment of AIDS.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described:
Embodiment: get Rhizoma Atractylodis 3500 grams, the Radix Aucklandiae 3500 grams, Flos Caryophylli 2500 grams, Cortex Mori 4000 grams, Radix Glycyrrhizae 4000 grams, Calculus Bovis 300 grams, Venenum Bufonis 50 grams, Realgar 10 grams, 10 grams, Cinnabaris, Calomelas 10 grams, Herba Menthae 2000 grams, 10 grams, Moschus, Fructus Crataegi 5000 grams, Herba Paederiae 2500 grams, Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 2500 grams.
The preparation method of medicine of the present invention is: be first placed in marmite by Rhizoma Atractylodis 3500 grams, the Radix Aucklandiae 3500 grams, Flos Caryophylli 2500 grams, Cortex Mori 4000 grams, Radix Glycyrrhizae 4000 grams, Fructus Crataegi 5000 grams, Herba Paederiae 2500 grams, Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 2500 grams, add water and cross the high 5 centimetres of immersions of powder 20 minutes, water is outwelled, adding water again, to cross powder high 5 centimetres, endure out with high heat, then endure 15 minutes with moderate heat, rapidly Herba Menthae 2000 grams is put in the marmite endured, use slow fire instead and endure 30 minutes, take out medicinal liquid, and then adding water, to cross powder high 5 centimetres, endures out with high heat, use slow fire instead and endure 25 minutes, take out medicinal liquid, and then adding water, to cross powder high 5 centimetres, endures out with high heat, use moderate heat instead 10 minutes, then endure 20 minutes with slow fire, take out medicinal liquid, then first time, for the second time, third time, the medicinal liquid one piece endured poured the interior moderate heat of marmite into when enduring to magma, using slow fire instead endures to when playing vesicle, rapidly with 100 grams of Chinese liquor, the Venenum Bufonis 50 grams that Venenum Bufonis 50 digests out being put in marmite in advance, use urgent greatly decocting medicinal herbs instead and remove fire rapidly when liquid plays bulla, ointment, then ointment is poured out and to dry in the shade or by oven for drying, the temperature of baking oven is between 45-55 DEG C, then by dry ointment and Calculus Bovis 300 grams, Realgar 10 grams, 10 grams, Cinnabaris, Calomelas 10 grams is placed on one piece and pulverized 300 mesh sieves, then medicated powder and 10 grams, Moschus are placed on one piece of mix homogeneously, make capsule, every capsules fills 0.3 gram.Each serving 0.3 gram, each serving 1, take 2 day, early, after supper under warm water clothes.
Medicine of the present invention has inhibiting HIV, Yin Yang balancing, regulates function, effect of promoting digestion and removing stagnation.
Medicine of the present invention is applicable to treat acquired immune deficiency syndrome (AIDS), cardinal symptom: heating, pharyngalgia, night sweat, nausea,vomiting,diarrhea, erythra, arthralgia, lymphadenectasis, Lymph nodes diameter >=1cm, without tenderness, without adhesion, hypomnesis, spirit are indifferent, headache, epilepsy and dementia.Blood test, can detect HIV-RNA and P24 antigen.
Treat the course for the treatment of: within 30 days, be 1 course for the treatment of, the lighter, 2-5 the course for the treatment of can cure, severe one, and 5-12 the course for the treatment of can cure.
Therapeutic effect: effective percentage 96%, cure rate 70%.
For showing the curative effect of medicine of the present invention, inclusive criteria: heating, pharyngalgia, night sweat, nausea,vomiting,diarrhea, erythra, arthralgia, lymphadenectasis, diameter >=1cm, without tenderness, without adhesion, more than 3 months persistent period; Lose weight more than 10%, hypomnesis, spirit be indifferent, headache, epilepsy and dementia etc.HIV-RNA and P24 antigen can be detected in blood.There are insecurity life cycle, intravenous injection drug use history, input the blood or blood product, the HIV antibody positive that detect without ANTI-HIV DRUGS and give birth to children.To treatment 100 examples carried out observation of curative effect, the age 9-65 year between, wherein man 50 example, female 50 example, treatment 100 routine average marks to test group and matched group, test group give 50 example, wherein, man 25 example, female 25 example; Matched group gives 50 examples, wherein, and man 25 example, female 25 example.Matched group State Intellectual Property Office's number of patent application " 011449519 " disclosed on 07 09th, 2003, the instructions of taking of denomination of invention " Chinese medicine composition for the treatment of acquired immune deficiency syndrome (AIDS) and preparation method thereof " is taken, and treats 2-12 the course for the treatment of; Test group Drug therapy of the present invention, take by drug administration method of the present invention, treat 2-12 the course for the treatment of, all with symptom: heating, pharyngalgia, night sweat, nausea,vomiting,diarrhea, erythra, arthralgia, lymphadenectasis, diameter >=2.2cm, without tenderness, without adhesion, become thin, spirit is indifferent, headache, dementia alleviates, blood examination, and in blood, HIV-RNA and P24 antigen is reduced to effectively; All with symptom: heating, pharyngalgia, night sweat, nausea,vomiting,diarrhea, erythra, arthralgia, lymphadenectasis, diameter >=2.2cm, without tenderness, without adhesion, become thin, spirit is indifferent, headache, dementia all disappears, blood examination, and in blood, HIV-RNA and P24 antigen is turned out cloudy as recovery from illness.
Statistical result shows:
Table 1, test group curative effect situation
Table 2, matched group curative effect situation
Result of the test shows, the effect of Drug therapy acquired immune deficiency syndrome (AIDS) of the present invention is better than matched group State Intellectual Property Office number of patent application " 011449519 " disclosed on 07 09th, 2003, the effect of denomination of invention " Chinese medicine composition for the treatment of acquired immune deficiency syndrome (AIDS) and preparation method thereof " treatment acquired immune deficiency syndrome (AIDS).
Model case: Bei Meng village, Shouzhang town, Yanggu County, the Meng so-and-so, man, 31 years old, on May 21st, 2010 examined, readme, and 2009 are found acquired immune deficiency syndrome (AIDS) by Liaocheng People's Hospital, has taken medicine more than a year, also bad, therefore examines.Clinical cardinal symptom: low grade fever, have sore throat, night sweat, feel sick, within 1 day, have loose bowels 5-6 time, membra arthralgia, lymphadenectasis, diameter 2.0cm, without tenderness, adhesion, body constitution is become thin, spirit is stupid, headache, blood examination, blood HIV antibody is positive, and clinical diagnosis is acquired immune deficiency syndrome (AIDS).Tell its all medicines of stopping using, change and take medicine of the present invention, the medicine taking back a course for the treatment of is taken by drug administration method of the present invention, within 30 days, examined afterwards, clinical symptoms: do not generated heat, throat is not bitterly, also night sweat, do not feel sick, have loose bowels gently, within one day, have loose bowels 2-3 time, membra arthralgia light, lymphadenectasis, diameter 1.5cm, tell the medicine of the present invention that it takes 10 courses for the treatment of again, still take it by drug administration method of the present invention, the medicine of the present invention taking 10 courses for the treatment of is examined again, readme, all symptoms are all good, ask and to take medicine the need of continuing, clinical symptoms: clinical without other symptom, Lymph nodes diameter 0.8cm, blood examination, blood HIV antibody is negative, for anti-recurrence, tell it and take a course for the treatment of of medicine of the present invention again, follow up a case by regular visits to and do not recur so far.
To illustrate: above-described embodiment is only limitted to explain and illustrates that invention of the present invention is conceived, but not the restriction to rights protection of the present invention, allly utilize conception of the present invention to the change of unsubstantiality of the present invention, all should protection scope of the present invention be belonged to.Those skilled in the art, according to the basic thought of rights protection of the present invention, can make various improvement or amendment, but, only otherwise depart from basic thought of the present invention, all within the scope of the present invention.
Claims (1)
1. treat the Chinese medicine composition of acquired immune deficiency syndrome (AIDS) for one kind, it is characterized in that: its preparation method is, first Rhizoma Atractylodis 3500 grams, the Radix Aucklandiae 3500 grams, Flos Caryophylli 2500 grams, Cortex Mori 4000 grams, Radix Glycyrrhizae 4000 grams, Fructus Crataegi 5000 grams, Herba Paederiae 2500 grams, Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 2500 grams are placed in marmite, add water and cross the high 5 centimetres of immersions of powder 20 minutes, water is outwelled, adding water again, to cross powder high 5 centimetres, endure out with high heat, then 15 minutes are endured with moderate heat, rapidly Herba Menthae 2000 grams is put in the marmite endured, use slow fire instead and endure 30 minutes, take out medicinal liquid, and then adding water, to cross powder high 5 centimetres, endures out with high heat, use slow fire instead and endure 25 minutes, take out medicinal liquid, and then adding water, to cross powder high 5 centimetres, endures out with high heat, use moderate heat instead 10 minutes, then endure 20 minutes with slow fire, take out medicinal liquid, then first time, for the second time, third time, the medicinal liquid one piece endured poured the interior moderate heat of marmite into when enduring to magma, using slow fire instead endures to when playing vesicle, rapidly with 100 grams of Chinese liquor, the Venenum Bufonis 50 grams that Venenum Bufonis 50 digests out being put in marmite in advance, use urgent greatly decocting medicinal herbs instead and remove fire rapidly when liquid plays bulla, ointment, then ointment is poured out and to dry in the shade or by oven for drying, the temperature of baking oven is between 45-55 DEG C, then by dry ointment and Calculus Bovis 300 grams, Realgar 10 grams, 10 grams, Cinnabaris, Calomelas 10 grams is placed on one piece and pulverized 300 mesh sieves, then medicated powder and 10 grams, Moschus are placed on one piece of mix homogeneously, make capsule, every capsules fills 0.3 gram.
Priority Applications (1)
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