CN103386056B - Anti-tumor traditional Chinese medicine troche and preparation method thereof - Google Patents
Anti-tumor traditional Chinese medicine troche and preparation method thereof Download PDFInfo
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Abstract
The invention discloses an anti-tumor medicine which mainly comprises scirpus fluviatilis, Caulis Spatholobi, Slender Dutchmanspipe Root, Astragalus membranaceus, Sculellaria barbata, Valeriana jatamansi Jones, hericium erinaceus, leech, Chinese blister beetle, pillworm, scarab, centipede, prepared turtle shell and dried toad skin. The medicine disclosed by the invention is complete in formula, brings out the best in each other and supports body resistance, repairs histocyte regeneration, reveres diseased cells to normal cells, and can effectively treat benign tumor. The traditional Chinese medicine is convenient to prepare and use, safe and free from toxic and side effects, so that the anti-tumor traditional Chinese medicine troche is an ideal anti-tumor medicine.
Description
Technical field
The invention discloses a kind of Chinese medicinal tablet, especially antineoplastic Chinese medicinal tablet and preparation method thereof.The invention belongs to Chinese medicine field.
Background technology
Tumor (Tumor) be body under various carcinogenic factor effects, some cells of local organization lose the normal regulation to its growth on gene level, cause its clonal abnormality hypertrophy and the abnormality that forms.Educational circles is generally divided into tumor optimum and pernicious two large classes.
Swollen neoplastic reason: the characteristic of our Chinese medical is that existing doctor trained in Western medicine has again the traditional Chinese medical science.Sickness rate is high now, China's case load is quite huge, 55%. tumors that have data to show to account for whole world case load are the all-environment and hereditary carcinogenic factors of gene glass to work in coordination with or sequential mode causes that DNA damages in itself, thereby activate proto-oncogene and (or) deactivation tumor suppressor gene, add the change of apoptosis regulator gene and (or) DNA-repair gene, then cause the abnormal of expression, target cell is transformed.The cell being converted is first the hypertrophy of clone's property more, through a very long multistage evolution process, one of them clones relatively unconfined amplification, pass through addition mutation, optionally form the sub-clone (heterogeneousization) with different characteristics, thereby obtain the ability (vicious transformation) that infiltrates and shift, form malignant tumor.
(1) number of tumor and size: the number of tumor, not of uniform size.Mostly be one, sometimes also can be a plurality of.The size of tumor and the character of tumor (optimum, pernicious), growth time and happening part have certain relation.Grow in body surface or larger endoceliac tumor can be grown very greatly sometimes, and the tumor growing in airtight narrow and small tract is generally less.The very big person of tumor, poor growth, mostly is optimum conventionally; Malignant growth is rapid, can bring adverse consequences in a short time, therefore normal childlike.
(2) shape of tumor: the shape of tumor is varied, has polypoid (exophytic growth), mamillary (exophytic growth), nodositas (expansive growth), lobulated (expansive growth), cryptomere (expansive growth), wellability enclosed mass shape (infiltrative growth), the plump shape (external companion's infiltrative growth) of diffusivity, ulcer shape companion infiltrative growth.Difference in shape and its happening part, tissue-derived, growth pattern and tumor good pernicious closely related.According to recent experiment both at home and abroad, show, negative aeroion has inhibitory action to the growth of transplanted tumor.
(3) color of tumor: the tangent plane of general tumor is greyish white or bois de rose, depending on its number containing blood volume, have or not hemorrhage, degeneration, necrosis etc.Some tumor can present different colors because it contains pigment.Therefore can be inferred as which kind of tumor according to the color of tumor.As lipoma is yellow, malignant melanoma is black, and hemangioma takes on a red color or kermesinus.
(4) hardness of tumor: with the ratio of the kind of tumor, the essence of tumor and interstitial and have or not degeneration, downright bad relevant.Essence is generally softer more than the tumor of interstitial; On the contrary, interstitial is generally harder more than the tumor of essence.Softer when tumor tissue necroses, there is calcification or harder when ossified.Lipoma is very soft, and osteoma is very hard.
In existing antineoplastic method, the patent No. 201210086706.5 discloses a kind of " a kind of anti-tumor drug " by name, by Radix Codonopsis, Fructus Ligustri Lucidi, Pericarpium Citri tangerinae, Flos Chrysanthemi, Rhizoma Paridis, Herba Taraxaci, Herba Patriniae, Periostracum Serpentis, Herba Schizonepetae, Flos Carthami, Herba Potentillae Discoloris, Fructus Forsythiae is that raw material is made, main dosage form is capsule, for the effect of anticancer and not as tablet ideal, can cause extra burden to patient's health.
Although the medicine providing in prior art more or less all has some curative effects on antitumor, part prescription brings certain toxic and side effects more or less can to patient's gastrointestinal, Liver and kidney.Generally speaking, for antineoplastic, treatment there is no desirable definite treatment by Chinese herbs medicine at present.
Summary of the invention
Present situation for existing antitumor deficiency, one of object of the present invention is to provide antineoplastic Chinese medicinal tablet, have and prepare simple, taking convenience, easy to carry, the obvious feature of action effect, this Chinese medicinal tablet has repair tissue cell regeneration, reverses the normal effect of disease cell, and it adopts comparatively common in the localities Chinese crude drug as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned Chinese medicinal tablet.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Anti-tumor Chinese medicine tablet, takes off the primary raw material of stating weight proportion and is prepared from: Rhizoma Sparganii 15-25 part, Caulis Spatholobi 15-25 part, Radix Aristolochiae 15-25 part, Radix Astragali 20-30 part, Herba Scutellariae Barbatae 20-30 part, Rhizoma valerianae latifoliae 30-40 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 50-150 part, Hirudo 1-5 part, Mylabris 1-5 part, Armadillidium 1-5 part, go-cart worm 1-5 part, Scolopendra 1-5 part, Carapax Trionycis (processed) 1-5 part, dry maxima skin 1-5 part.
Anti-tumor Chinese medicine tablet, preferred proportioning, takes off the primary raw material of stating weight proportion and is prepared from: Rhizoma Sparganii 18-23 part, Caulis Spatholobi 18-23 part, Radix Aristolochiae 18-23 part, Radix Astragali 23-28 part, Herba Scutellariae Barbatae 23-28 part, Rhizoma valerianae latifoliae 33-38 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 80-120 part, Hirudo 2-4 part, Mylabris 2-4 part, Armadillidium 2-4 part, go-cart worm 2-4 part, Scolopendra 2-4 part, Carapax Trionycis (processed) 2-4 part, dry maxima skin 2-4 part.
Anti-tumor Chinese medicine tablet, better preferred proportioning, takes off the primary raw material of stating weight proportion and is prepared from: 20 parts of Rhizoma Sparganii, 20 parts of Caulis Spatholobis, 20 parts of Radix Aristolochiaes, 25 parts of the Radixs Astragali, 25 parts of Herba Scutellariae Barbataes, 35 parts of Rhizoma valerianae latifoliaes, 100 parts of Hericium erinaceus (Bull. Ex Fr.) Pers.es, 3 parts of Hirudos, 3 parts of Mylabris, 3 parts of Armadillidiums, 3 parts of go-cart worms, 3 parts of Scolopendras, 3 parts of Carapax Trionycis (processed)s, 3 parts of dry maxima skins.
The preparation method of above-mentioned Chinese medicinal tablet, preparation process is as follows:
(1) Rhizoma Sparganii, Caulis Spatholobi, Radix Aristolochiae, the Radix Astragali, Herba Scutellariae Barbatae, Rhizoma valerianae latifoliae, Hericium erinaceus (Bull. Ex Fr.) Pers. are pulverized, cross 80-120 mesh sieve, obtain fine powder;
(2) Carapax Trionycis (processed) and dry maxima skin are soaked to 20-40 minute completely with vinegar, taking-up is dried, and obtains vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed;
(3) Hirudo, Mylabris, Armadillidium, go-cart worm, Scolopendra, vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed are ground into fine powder, cross 120-140 mesh sieve (preferably 130);
(4) by step (3) gained fine powder mix homogeneously, by temperature, be that preferably the cold water of 30 ℃ soaks 2 hours, water consumption is 3-4 times (preferably 3.5 times) of described fine powder weight;
(5) step (4) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume obtains concentrated solution;
(6) gained fine powder in step (1) is poured in the concentrated solution of step (5) gained, fully stirred into thick paste; Thick paste being dried to 1-2 hour, obtain oven dry thing, is dry at 70-90 ℃ in temperature;
(7) step (6) gains are measured according to 0.3-0.7g/ sheet, according to the preparation for processing of tablet, be pressed into circular or other forms of lamellar dosage form.
The preparation method of above-mentioned Chinese medicinal tablet, preferred scheme is: step (1) is crossed 90-110 mesh sieve (preferably 100 mesh sieves).
The preparation method of above-mentioned Chinese medicinal tablet, preferred scheme is: step (2) is soaked 25-35 minute (preferably 30 minutes).
The preparation method of above-mentioned Chinese medicinal tablet, preferred scheme is: step (6) is dried 1.3-1.8 hour (preferably 1.5 hours).
The preparation method of above-mentioned Chinese medicinal tablet, preferred scheme is: step (6) baking temperature is 75-85 ℃ (preferably 80 ℃).
The preparation method of above-mentioned Chinese medicinal tablet, preferred scheme is: the specification of step (7) tablet is 0.4-0.6g/ sheet (preferably 0.5g).
Using method: for making the present invention reach optimum therapeuticing effect, when edible, after 1 hour, take after the meal, with warm boiled water, 3 times on the one, each 3 grams.
This Chinese medicinal tablet is remarkable to opposing tumor effect, each is organized medicine and complements each other, both helped the absorption running of medicine, anti-all medicines are sweet stagnant cool cold again, can mend the gas of strengthening spleen and lung, invigorating spleen to remove dampness, again can heat-clearing and toxic substances removing, repair tissue cell regeneration, reverses disease cell normal, finally reach anticancer object, long-term taking can play good therapeutical effect to tumor.
Anti-tumor Chinese medicine tablet, the pharmacological effect of each crude drug is respectively:
Rhizoma Sparganii: flavor efficacy: bitter in the mouth, property is flat.Removing blood stasis, circulation of qi promoting, removing food stagnancy pain relieving.Clinical practice: be applicable to kinds of tumors, as ovarian cancer, cervical cancer, hepatocarcinoma etc.The ovarian cancer that compatibility treatment QI and blood knot amasss, the blood stasis stasis of blood is stagnant, the cervical cancers etc. such as normal and Rhizoma Cyperi, Rhizoma Curcumae, Radix Arnebiae (Radix Lithospermi), Fructus Fici Pumilae.The hepatocarcinoma that compatibility treatment qi depression to blood stasis, the pyretic toxicity such as conventional Herba Hedyotidis Diffusae, Pericarpium Arecae, Poria, Rhizoma Curcumae pent up.In addition these product are also applicable to stagnation of QI and blood, abdominal part caking, hepatosplenomegaly, amenorrhea stomachache, food stagnation distending pain etc.
Caulis Spatholobi: bitter, sweet, temperature.Return liver, kidney channel.Relaxing muscles and tendons to promote blood circulation; Nourishing blood for regulating menstruation.Main numb hand and foot; Quadriplegia; Rheumatic arthralgia; Women has through uncomfortable; Dysmenorrhea; Amenorrhea.Enrich blood, invigorate blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.
Radix Aristolochiae: Radix Aristolochiae is the stem of Radix Cocculi Orbiculati, Radix Cocculi Orbiculati another name: lead a cow in Radix Aristolochiae, Ma Geluo, little Herba Ophioglossi, Cortex Ampelopsis Aconitifoliae Radicis, burst rattan, the same rattan of family, open country, hair Radix seu Caulis fici Martinii, slabstone rattan, mouse rattan, Radix seu Caulis fici Martinii, shallow bid rattan, cattle string, bitter in the mouth, property is put down.Function expelling wind and removing dampness; Regulating QI pain relieving; Inducing diuresis to remove edema.Cure mainly rheumatic arthralgia; Traumatic injury; Stomachache; Stomachache; Edema; Stranguria.
The Radix Astragali: sweet, tepor.Gui Jing: return lung, spleen, liver, kidney channel.The Radix Astragali has the effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.Be used for the treatment of the deficiency of vital energy weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.The invigorating middle warmer of Radix Astragali Preparata QI invigorating, raw by consolidating superficial resistance holder skin ulcer.
Herba Scutellariae Barbatae: pungent, bitter, cold.Return lung, liver, kidney channel.Heat-clearing and toxic substances removing, blood stasis dispelling diuresis.For furuncle swelling toxin, laryngopharynx swelling and pain, venom, falls and flutters the pain of injury, edema, jaundice.
Rhizoma valerianae latifoliae: acrid in the mouth; Micro-hardship; Warm in nature.Regulating the flow of Qi and the middle Jiao, dispelling cold and removing dampness; Promoting blood circulation and detumescence.Main abdominal distention; Tell and have loose bowels; Infantile malnutrition; Anemofrigid-damp arthralgia; Limb air water is swollen; Menoxenia; Traumatic injury; Furuncle.
Hericium erinaceus (Bull. Ex Fr.) Pers.: antiulcer and antiinflammatory action.Antitumor action.Liver protection function, increases immunity, anti-aging effects.Improve body's hypoxia tolerance, increase heart blood output, accelerate body blood circulation.Reduce the effect of blood glucose and blood fat.
Hirudo: salty hardship, flat, poisonous.Have that treatment menstruation apolipsis, lump in the abdomen stomachache, blood-retention, traumatic blood stasis are had a pain, the effect of carbuncle erysipelas.
Mylabris: acrid in the mouth; Warm in nature; Poisonous.Counteracting toxic substances phagedenoma; Removing blood stasis eliminating stagnation.Main carbuncle; Scrofula; Stubborn dermatitis; Amenorrhea; Lump in the abdomen; Cancerous protuberance.Yong Yu WEIJIA lump, stubborn dermatitis for many years, scrofula, wart, carbuncle is not burst, the dead flesh of malignant boil.
Armadillidium: acid, temperature, nontoxic.For relieving sore throat and pain, removing blood stasis with potent drugs diuretic.Removing blood stasis, diuretic, removing toxic substances, pain relieving.Control chronic malaria malaria with splenomegaly, amenorrhea lump in the abdomen, urinary obstruction, infantile convulsion locked jaw, ability to speak pain, all skin ulcers of thrush.1. < < herbal classic > >: " main stranguria due to disorder of QI dysuria, married woman closes abdominal mass due to blood stasis the moon, Xian, Chi, cold and heat, dredging water passages." 2. < < Japan hanako materia medica > >: " diuresis can be had an abortion." 3. < < detailed outline > >: control chronic malaria cold and heat, wind worm dental pain, children's's locked jaw infantile convulsion, thrush, variola is fallen dimple, and solution is penetrated work poison, spider venom, scutige is pleasant.4. < < book on Chinese herbal medicine is asked former > >: the main cold and heat stasis of blood is long-pending, damp-phlegm, larynx disease, infantile convulsion, disorders of blood, dyspnea with rapid respiration.
Go-cart worm: salty, cold, poisonous.Arresting convulsion, removing blood stasis with potent drugs, relieving constipation, counteracting toxic substances.Control infantile convulsion, demented, lump in the abdomen, dysphagia and regurgitation, abdominal distention constipation, gonorrhea, infantile malnutrition, dysentery, anal fistula, furuncle is swollen, malignant boil.
Scolopendra: can make the soft contracting of lump, pressure symptom is alleviated, and can make the transference cures such as distending pain, and ulcer is calmed down, and the state of an illness significantly takes a turn for the better.
Carapax Trionycis (processed): salty, cold.Return liver, kidney channel.Can suppress the connective tissue proliferation of liver, spleen, improve plasma protein level, and the effect such as antitumor.
Dry maxima skin: heat-clearing and toxic substances removing, diuretic relieving distension.Control carbuncle, toxic swelling, scrofula, tumor, infantile malnutrition abdominal distention, chronic tracheitis
Chinese medicinal tablet of the present invention is based on Chinese medicine antineoplastic principle.The Chinese medicinal material of selecting all has blood circulation promoting and blood stasis dispelling, the body resistance strengthening and constitution consolidating, and repair tissue cell regeneration, reverses the normal effect of disease cell, and in addition, excellent results of the present invention also shows:
1,this prescription meets Chinese medicine principle and tumor patient body and mind feature completely, under the prerequisite of general principle, can have different prescriptions according to different crowd, and function is different.
2,medicine source is easy to get, and medical material is with low cost, can relieve patient ' s burden.
The specific embodiment
Below in conjunction with embodiment and experimental example, describe technical scheme of the present invention in detail, but protection domain is not by this restriction.
embodiment 1antineoplastic Chinese medicinal tablet, takes off the primary raw material of stating weight proportion and is prepared from: 15 grams of Rhizoma Sparganii, 15 grams of Caulis Spatholobis, 15 grams of Radix Aristolochiaes, 20 grams of the Radixs Astragali, 20 grams of Herba Scutellariae Barbataes, 30 grams of Rhizoma valerianae latifoliaes, 50 grams of Hericium erinaceus (Bull. Ex Fr.) Pers.es, 1 gram of Hirudo, 1 gram of Mylabris, 1 gram of Armadillidium, 1 gram of go-cart worm, 1 gram of Scolopendra, 1 gram of Carapax Trionycis (processed), 1 gram of dry maxima skin.
The preparation method of above-mentioned Chinese medicinal tablet, step is:
(1) Rhizoma Sparganii, Caulis Spatholobi, Radix Aristolochiae, the Radix Astragali, Herba Scutellariae Barbatae, Rhizoma valerianae latifoliae, Hericium erinaceus (Bull. Ex Fr.) Pers. are pulverized, cross 80 mesh sieves, obtain fine powder;
(2) Carapax Trionycis (processed) and dry maxima skin are soaked 20 minutes completely with vinegar, taking-up is dried, and obtains vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed;
(3) Hirudo, Mylabris, Armadillidium, go-cart worm, Scolopendra, vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed are ground into fine powder, cross 120 mesh sieves;
(4) by step (3) gained fine powder mix homogeneously, by temperature, be that preferably the cold water of 30 ℃ soaks 2 hours, water consumption is 3 of described fine powder weight;
(5) step (4) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume obtains concentrated solution;
(6) gained fine powder in step (1) is poured in the concentrated solution of step (5) gained, fully stirred into thick paste; Thick paste being dried to 1, obtain oven dry thing, is 70 in temperature;
(7) step (6) gains are measured according to 0.3g/ sheet, according to the preparation for processing of tablet, be pressed into circular or other forms of lamellar dosage form.
embodiment 2antineoplastic Chinese medicinal tablet, takes off the primary raw material of stating weight proportion and is prepared from: 25 grams of Rhizoma Sparganii, 25 grams of Caulis Spatholobis, 25 grams of Radix Aristolochiaes, 30 grams of the Radixs Astragali, 30 grams of Herba Scutellariae Barbataes, 40 grams of Rhizoma valerianae latifoliaes, 150 grams of Hericium erinaceus (Bull. Ex Fr.) Pers.es, 5 grams of Hirudos, 5 grams of Mylabris, 5 grams of Armadillidiums, 5 grams of go-cart worms, 5 grams of Scolopendras, 5 grams of Carapax Trionycis (processed)s, 5 grams of dry maxima skins.
The preparation method of above-mentioned Chinese medicinal tablet, step is:
(1) Rhizoma Sparganii, Caulis Spatholobi, Radix Aristolochiae, the Radix Astragali, Herba Scutellariae Barbatae, Rhizoma valerianae latifoliae, Hericium erinaceus (Bull. Ex Fr.) Pers. are pulverized, cross 120 mesh sieves, obtain fine powder;
(2) Carapax Trionycis (processed) and dry maxima skin are soaked 40 minutes completely with vinegar, taking-up is dried, and obtains vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed;
(3) Hirudo, Mylabris, Armadillidium, go-cart worm, Scolopendra, vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed are ground into fine powder, cross 140 mesh sieves;
(4) by step (3) gained fine powder mix homogeneously, by temperature, be that preferably the cold water of 30 ℃ soaks 2 hours, water consumption is 4 times of described fine powder weight;
(5) step (4) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume obtains concentrated solution;
(6) gained fine powder in step (1) is poured in the concentrated solution of step (5) gained, fully stirred into thick paste; Thick paste being dried 2 hours, obtain oven dry thing, is dry at 90 ℃ in temperature;
(7) step (6) gains are measured according to 0.7g/ sheet, according to the preparation for processing of tablet, be pressed into circular or other forms of lamellar dosage form.
embodiment 3antineoplastic Chinese medicinal tablet, takes off the primary raw material of stating weight proportion and is prepared from: 18 grams of Rhizoma Sparganii, 18 grams of Caulis Spatholobis, 18 parts of Radix Aristolochiaes, 23 parts of the Radixs Astragali, 23 parts of Herba Scutellariae Barbataes, 33 parts of Rhizoma valerianae latifoliaes, 80 parts of Hericium erinaceus (Bull. Ex Fr.) Pers.es, 2 parts of Hirudos, 2 parts of Mylabris, 2 parts of Armadillidiums, 2 parts of go-cart worms, 2 parts of Scolopendras, 2 parts of Carapax Trionycis (processed)s, 2 parts of dry maxima skins.
The preparation method of above-mentioned Chinese medicinal tablet, step is:
(1) Rhizoma Sparganii, Caulis Spatholobi, Radix Aristolochiae, the Radix Astragali, Herba Scutellariae Barbatae, Rhizoma valerianae latifoliae, Hericium erinaceus (Bull. Ex Fr.) Pers. are pulverized, cross 90 mesh sieves, obtain fine powder;
(2) Carapax Trionycis (processed) and dry maxima skin are soaked 25 minutes completely with vinegar, taking-up is dried, and obtains vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed;
(3) Hirudo, Mylabris, Armadillidium, go-cart worm, Scolopendra, vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed are ground into fine powder, cross 125 mesh sieves;
(4) by step (3) gained fine powder mix homogeneously, by temperature, be that preferably the cold water of 30 ℃ soaks 2 hours, water consumption is 3.3 times of described fine powder weight;
(5) step (4) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume obtains concentrated solution;
(6) gained fine powder in step (1) is poured in the concentrated solution of step (5) gained, fully stirred into thick paste; Thick paste being dried 1.3 hours, obtain oven dry thing, is dry at 75 ℃ in temperature;
(7) step (6) gains are measured according to 0.4g/ sheet, according to the preparation for processing of tablet, be pressed into circular or other forms of lamellar dosage form.
embodiment 4antineoplastic Chinese medicinal tablet, takes off the primary raw material of stating weight proportion and is prepared from: 23 grams of Rhizoma Sparganii, 23 grams of Caulis Spatholobis, 23 grams of Radix Aristolochiaes, 28 grams of the Radixs Astragali, 28 grams of Herba Scutellariae Barbataes, 38 grams of Rhizoma valerianae latifoliaes, 120 grams of Hericium erinaceus (Bull. Ex Fr.) Pers.es, 4 grams of Hirudos, 4 grams of Mylabris, 4 grams of Armadillidiums, 4 grams of go-cart worms, 4 grams of Scolopendras, 4 grams of Carapax Trionycis (processed)s, 4 grams of dry maxima skins.
The preparation method of above-mentioned Chinese medicinal tablet, step is:
(1) Rhizoma Sparganii, Caulis Spatholobi, Radix Aristolochiae, the Radix Astragali, Herba Scutellariae Barbatae, Rhizoma valerianae latifoliae, Hericium erinaceus (Bull. Ex Fr.) Pers. are pulverized, cross 110 mesh sieves, obtain fine powder;
(2) Carapax Trionycis (processed) and dry maxima skin are soaked 35 minutes completely with vinegar, taking-up is dried, and obtains vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed;
(3) Hirudo, Mylabris, Armadillidium, go-cart worm, Scolopendra, vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed are ground into fine powder, cross 135 mesh sieves;
(4) by step (3) gained fine powder mix homogeneously, by temperature, be that preferably the cold water of 30 ℃ soaks 2 hours, water consumption is 3.8 times of described fine powder weight;
(5) step (4) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume obtains concentrated solution;
(6) gained fine powder in step (1) is poured in the concentrated solution of step (5) gained, fully stirred into thick paste; Thick paste being dried 1.8 hours, obtain oven dry thing, is dry at 85 ℃ in temperature;
(7) step (6) gains are measured according to 0.6g/ sheet, according to the preparation for processing of tablet, be pressed into circular or other forms of lamellar dosage form.
embodiment 5:antineoplastic Chinese medicinal tablet, takes off the primary raw material of stating weight proportion and is prepared from: 20 grams of Rhizoma Sparganii, 20 grams of Caulis Spatholobis, 20 grams of Radix Aristolochiaes, 25 grams of the Radixs Astragali, 25 grams of Herba Scutellariae Barbataes, 35 grams of Rhizoma valerianae latifoliaes, 100 grams of Hericium erinaceus (Bull. Ex Fr.) Pers.es, 3 grams of Hirudos, 3 grams of Mylabris, 3 grams of Armadillidiums, 3 grams of go-cart worms, 3 grams of Scolopendras, 3 grams of Carapax Trionycis (processed)s, 3 grams of dry maxima skins.
(1) Rhizoma Sparganii, Caulis Spatholobi, Radix Aristolochiae, the Radix Astragali, Herba Scutellariae Barbatae, Rhizoma valerianae latifoliae, Hericium erinaceus (Bull. Ex Fr.) Pers. are pulverized, cross 100 mesh sieves, obtain fine powder;
(2) Carapax Trionycis (processed) and dry maxima skin are soaked 30 minutes completely with vinegar, taking-up is dried, and obtains vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed;
(3) Eupolyphaga Seu Steleophaga, Hirudo, Mylabris, Armadillidium, go-cart worm, Scolopendra, vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed are ground into fine powder, cross 130 mesh sieves;
(4) by step (3) gained fine powder mix homogeneously, by temperature, be that preferably the cold water of 30 ℃ soaks 2 hours, water consumption is 3.5 times of described fine powder weight;
(5) step (4) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume obtains concentrated solution;
(6) gained fine powder in step (1) is poured in the concentrated solution of step (5) gained, fully stirred into thick paste; Thick paste being dried 1.5 hours, obtain oven dry thing, is dry at 80 ℃ in temperature;
(7) step (6) gains are measured according to 0.5g/ sheet, according to the preparation for processing of tablet, be pressed into circular or other forms of lamellar dosage form.
Using method: for making the present invention reach optimum therapeuticing effect, when edible, after 1 hour, take after the meal, with warm boiled water, 3 times on the one, each 10 grams.
experimental example:object is to verify whether this Chinese medicinal tablet has curative effect to antitumor.
The < < new Chinese medicine guideline of clinical investigations > > formulating according to Ministry of Public Health 1993 is diagnosis basis, totally 200 routine tumor patients, and the mean age is 45 years old.Random division is administration group and matched group.
The previous day before experiment, record patient's health, look over patient body symptom every day, guarantee that administration group and matched group situation are basically identical.Administration group edible this product embodiments 5 gained Chinese medicinal tablets every day 10 days are a course for the treatment of.Check patient body situation every day, make a record.Result is as following table 1:
Table 1:
Self-induction symptom and emotion changes result are as table 2:
Table 2:
?when administration group (Chinese medicinal tablet of the present invention) is used 10 days, most patient sensory symptoms obviously alleviates, obviously feel to take a favorable turn in affected part, patient's emotion takes a turn for the better, medication in the time of 20 days patient substantially painless, obviously sensation tumor deliquescing, drug withdrawal a period of time has no repeatedly, and the state of an illness is better controlled, and tumor is without diffusion.Matched group take medicine after curative effect obvious, but after drug withdrawal, 94% patient is recurred again.
Through clinical trial, prove, Chinese medicinal tablet of the present invention is on antitumor, and effective percentage is 97%, and cure rate is 91%, than oral western medicine effective percentage, exceeds 18%, and cure rate exceeds 62%, makes patient really feel that tumor is controlled; And can not cause any burden to patient's health.Chinese medicinal tablet instant effect of the present invention, can reach the object of rapid alleviation patient misery, and relapse rate is low, is a kind of Chinese medicinal tablet of antineoplastic safely and effectively.
Claims (10)
1. the preparation method of antineoplastic Chinese medicinal tablet, is characterized in that: take off the raw material of stating weight proportion: 20 parts of Rhizoma Sparganii, 20 parts of Caulis Spatholobis, 20 parts of Radix Aristolochiaes, 25 parts of the Radixs Astragali, 25 parts of Herba Scutellariae Barbataes, 35 parts of Rhizoma valerianae latifoliaes, 100 parts of Hericium erinaceus (Bull. Ex Fr.) Pers.es, 3 parts of Hirudos, 3 parts of Mylabris, 3 parts of Armadillidiums, 3 parts of go-cart worms, 3 parts of Scolopendras, 3 parts of Carapax Trionycis (processed)s, 3 parts of dry maxima skins; Step is as follows:
(1) Rhizoma Sparganii, Caulis Spatholobi, Radix Aristolochiae, the Radix Astragali, Herba Scutellariae Barbatae, Rhizoma valerianae latifoliae, Hericium erinaceus (Bull. Ex Fr.) Pers. are pulverized, cross 90-110 mesh sieve, obtain fine powder;
(2) Carapax Trionycis (processed) and dry maxima skin are soaked to 20-40 minute completely with vinegar, taking-up is dried, and obtains vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed;
(3) Hirudo, Mylabris, Armadillidium, go-cart worm, Scolopendra, vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed are ground into fine powder, cross 120-140 mesh sieve;
(4) by step (3) gained fine powder mix homogeneously, by temperature, be that preferably the cold water of 30 ℃ soaks 2 hours, water consumption is 3-4 times of described fine powder weight;
(5) step (4) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume obtains concentrated solution;
(6) gained fine powder in step (1) is poured in the concentrated solution of step (5) gained, fully stirred into thick paste; Thick paste being dried to 1-2 hour, obtain oven dry thing, is dry at 70-90 ℃ in temperature;
(7) step (6) gains are measured according to 0.3-0.7g/ sheet, according to the preparation for processing of tablet, be pressed into circular or other forms of lamellar dosage form.
2. preparation method according to claim 1, is characterized in that: step (1) is crossed 100 mesh sieves.
3. preparation method according to claim 1, is characterized in that: step (2) is soaked 25-35 minute.
4. preparation method according to claim 3, is characterized in that: step (2) is soaked 30 minutes.
5. preparation method according to claim 1, is characterized in that: step (6) is dried 1.3-1.8 hour.
6. preparation method according to claim 5, is characterized in that: step (6) is dried 1.5 hours.
7. preparation method according to claim 1, is characterized in that: step (6) baking temperature is 75-85 ℃.
8. preparation method according to claim 7, is characterized in that: step (6) baking temperature is 80 ℃.
9. preparation method according to claim 1, is characterized in that: the specification of step (7) tablet is 0.4-0.6g/ sheet.
10. preparation method according to claim 9, is characterized in that: the specification of step (7) tablet is 0.5g/ sheet.
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| CN101670071A (en) * | 2009-09-25 | 2010-03-17 | 卢速江 | Traditional Chinese medicine preparation for treating cancer and preparation method thereof |
| CN102772745A (en) * | 2012-08-21 | 2012-11-14 | 卢速江 | Chinese medicinal preparation for treating cancer and preparation method thereof |
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| CN101670071A (en) * | 2009-09-25 | 2010-03-17 | 卢速江 | Traditional Chinese medicine preparation for treating cancer and preparation method thereof |
| CN102772745A (en) * | 2012-08-21 | 2012-11-14 | 卢速江 | Chinese medicinal preparation for treating cancer and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
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Free format text: CORRECT: ADDRESS; FROM: 256600 BINZHOU, SHANDONG PROVINCE TO: 226100 NANTONG, JIANGSU PROVINCE |
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| TR01 | Transfer of patent right |
Effective date of registration: 20150416 Address after: 226100 Nantong, Haimen City, Haimen City, Hai Tong Road, No. 207 Patentee after: Haimen Jinqilin Rosewood Investment and Development Co., Ltd. Address before: 256600, No. two, 661 the Yellow River Road, Bincheng District, Shandong, Binzhou Patentee before: Liu Ying |