CN103386056A - Anti-tumor traditional Chinese medicine troche and preparation method thereof - Google Patents
Anti-tumor traditional Chinese medicine troche and preparation method thereof Download PDFInfo
- Publication number
- CN103386056A CN103386056A CN2013103189542A CN201310318954A CN103386056A CN 103386056 A CN103386056 A CN 103386056A CN 2013103189542 A CN2013103189542 A CN 2013103189542A CN 201310318954 A CN201310318954 A CN 201310318954A CN 103386056 A CN103386056 A CN 103386056A
- Authority
- CN
- China
- Prior art keywords
- parts
- processed
- preparation
- tumor
- preferred
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002360 preparation method Methods 0.000 title claims description 28
- 239000003814 drug Substances 0.000 title abstract description 29
- 230000000259 anti-tumor effect Effects 0.000 title abstract description 15
- 240000000588 Hericium erinaceus Species 0.000 claims abstract description 20
- 235000007328 Hericium erinaceus Nutrition 0.000 claims abstract description 20
- 239000000843 powder Substances 0.000 claims description 35
- 235000021419 vinegar Nutrition 0.000 claims description 35
- 239000000052 vinegar Substances 0.000 claims description 35
- 241000722823 Armadillidium Species 0.000 claims description 19
- 241000237903 Hirudo Species 0.000 claims description 19
- 241000124079 Mylabris Species 0.000 claims description 19
- 241000131808 Scolopendra Species 0.000 claims description 19
- 244000309464 bull Species 0.000 claims description 19
- 239000009636 Huang Qi Substances 0.000 claims description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 18
- 239000002994 raw material Substances 0.000 claims description 13
- 230000000118 anti-neoplastic effect Effects 0.000 claims description 12
- 239000002552 dosage form Substances 0.000 claims description 8
- 238000009835 boiling Methods 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 7
- 241000726094 Aristolochia Species 0.000 claims description 3
- 241000545442 Radix Species 0.000 claims description 3
- 238000007654 immersion Methods 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 abstract description 36
- 230000000694 effects Effects 0.000 abstract description 18
- 230000008929 regeneration Effects 0.000 abstract description 4
- 238000011069 regeneration method Methods 0.000 abstract description 4
- 230000008439 repair process Effects 0.000 abstract description 4
- 231100000331 toxic Toxicity 0.000 abstract description 3
- 230000002588 toxic effect Effects 0.000 abstract description 3
- 241000045403 Astragalus propinquus Species 0.000 abstract 1
- 241000559235 Bolboschoenus fluviatilis Species 0.000 abstract 1
- 241000258920 Chilopoda Species 0.000 abstract 1
- 241000545744 Hirudinea Species 0.000 abstract 1
- 241000623906 Lytta vesicatoria Species 0.000 abstract 1
- 241000130993 Scarabaeus <genus> Species 0.000 abstract 1
- 241000270666 Testudines Species 0.000 abstract 1
- 241000606265 Valeriana jatamansi Species 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 24
- 210000004369 blood Anatomy 0.000 description 24
- 230000012010 growth Effects 0.000 description 12
- 208000002193 Pain Diseases 0.000 description 10
- 231100000614 poison Toxicity 0.000 description 9
- 210000004185 liver Anatomy 0.000 description 7
- 229940079593 drug Drugs 0.000 description 6
- 241000345998 Calamus manan Species 0.000 description 5
- 206010007247 Carbuncle Diseases 0.000 description 5
- 206010010904 Convulsion Diseases 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 5
- 230000036461 convulsion Effects 0.000 description 5
- 230000007812 deficiency Effects 0.000 description 5
- 210000003734 kidney Anatomy 0.000 description 5
- 235000012950 rattan cane Nutrition 0.000 description 5
- 210000001519 tissue Anatomy 0.000 description 5
- 239000003440 toxic substance Substances 0.000 description 5
- 206010000087 Abdominal pain upper Diseases 0.000 description 4
- 201000000736 Amenorrhea Diseases 0.000 description 4
- 206010001928 Amenorrhoea Diseases 0.000 description 4
- 208000006820 Arthralgia Diseases 0.000 description 4
- 206010030113 Oedema Diseases 0.000 description 4
- 208000004880 Polyuria Diseases 0.000 description 4
- 210000001015 abdomen Anatomy 0.000 description 4
- 231100000540 amenorrhea Toxicity 0.000 description 4
- 230000035619 diuresis Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 210000000952 spleen Anatomy 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 206010017553 Furuncle Diseases 0.000 description 3
- 208000015817 Infant Nutrition disease Diseases 0.000 description 3
- 208000025747 Rheumatic disease Diseases 0.000 description 3
- 206010040943 Skin Ulcer Diseases 0.000 description 3
- 208000019790 abdominal distention Diseases 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- 239000002934 diuretic Substances 0.000 description 3
- 230000001882 diuretic effect Effects 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 201000007227 lymph node tuberculosis Diseases 0.000 description 3
- 201000004792 malaria Diseases 0.000 description 3
- 230000000505 pernicious effect Effects 0.000 description 3
- 230000007096 poisonous effect Effects 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 230000000552 rheumatic effect Effects 0.000 description 3
- 231100000019 skin ulcer Toxicity 0.000 description 3
- 238000005728 strengthening Methods 0.000 description 3
- 230000008961 swelling Effects 0.000 description 3
- 241000283690 Bos taurus Species 0.000 description 2
- 206010007134 Candida infections Diseases 0.000 description 2
- 206010008342 Cervix carcinoma Diseases 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 2
- 201000004624 Dermatitis Diseases 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- 241000628997 Flos Species 0.000 description 2
- 206010020880 Hypertrophy Diseases 0.000 description 2
- 206010024612 Lipoma Diseases 0.000 description 2
- 208000019255 Menstrual disease Diseases 0.000 description 2
- 208000007027 Oral Candidiasis Diseases 0.000 description 2
- 206010033128 Ovarian cancer Diseases 0.000 description 2
- 206010061535 Ovarian neoplasm Diseases 0.000 description 2
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 2
- 241000287411 Turdidae Species 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 description 2
- 230000005856 abnormality Effects 0.000 description 2
- 230000001093 anti-cancer Effects 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 230000000711 cancerogenic effect Effects 0.000 description 2
- 201000003984 candidiasis Diseases 0.000 description 2
- 231100000315 carcinogenic Toxicity 0.000 description 2
- 201000010881 cervical cancer Diseases 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 230000007850 degeneration Effects 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 230000008451 emotion Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 230000003211 malignant effect Effects 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 230000005906 menstruation Effects 0.000 description 2
- 230000003389 potentiating effect Effects 0.000 description 2
- 230000002441 reversible effect Effects 0.000 description 2
- 230000008736 traumatic injury Effects 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 206010001580 Albuminuria Diseases 0.000 description 1
- 241000563984 Ampelopsis Species 0.000 description 1
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 241000756943 Codonopsis Species 0.000 description 1
- 230000033616 DNA repair Effects 0.000 description 1
- 208000019505 Deglutition disease Diseases 0.000 description 1
- 206010012289 Dementia Diseases 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 201000000297 Erysipelas Diseases 0.000 description 1
- 241001489978 Eupolyphaga Species 0.000 description 1
- 206010018367 Glomerulonephritis chronic Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 206010018612 Gonorrhoea Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 208000004044 Hypesthesia Diseases 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 208000029951 Laryngeal disease Diseases 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 235000009388 Parthenocissus quinquefolia Nutrition 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 241001619461 Poria <basidiomycete fungus> Species 0.000 description 1
- 102000052575 Proto-Oncogene Human genes 0.000 description 1
- 108700020978 Proto-Oncogene Proteins 0.000 description 1
- 206010037714 Quadriplegia Diseases 0.000 description 1
- 208000004680 Rectal Fistula Diseases 0.000 description 1
- 108700005075 Regulator Genes Proteins 0.000 description 1
- 206010067171 Regurgitation Diseases 0.000 description 1
- 241000220317 Rosa Species 0.000 description 1
- 208000001203 Smallpox Diseases 0.000 description 1
- 206010041660 Splenomegaly Diseases 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 206010044302 Tracheitis Diseases 0.000 description 1
- 102000044209 Tumor Suppressor Genes Human genes 0.000 description 1
- 108700025716 Tumor Suppressor Genes Proteins 0.000 description 1
- 241000870995 Variola Species 0.000 description 1
- 208000000260 Warts Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 206010000210 abortion Diseases 0.000 description 1
- 231100000176 abortion Toxicity 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 206010002156 anal fistula Diseases 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000767 anti-ulcer Effects 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- 229940041181 antineoplastic drug Drugs 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 230000002308 calcification Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 208000035250 cutaneous malignant susceptibility to 1 melanoma Diseases 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000009849 deactivation Effects 0.000 description 1
- 208000002925 dental caries Diseases 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 206010013990 dysuria Diseases 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 208000001786 gonorrhea Diseases 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000007773 growth pattern Effects 0.000 description 1
- 201000011066 hemangioma Diseases 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 206010019847 hepatosplenomegaly Diseases 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 208000034783 hypoesthesia Diseases 0.000 description 1
- 210000003026 hypopharynx Anatomy 0.000 description 1
- 230000007954 hypoxia Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 201000001441 melanoma Diseases 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 230000001613 neoplastic effect Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 208000008798 osteoma Diseases 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 230000001047 pyretic effect Effects 0.000 description 1
- 208000010540 rapid respiration Diseases 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 201000010153 skin papilloma Diseases 0.000 description 1
- 239000002708 spider venom Substances 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000000472 traumatic effect Effects 0.000 description 1
- 201000002327 urinary tract obstruction Diseases 0.000 description 1
- 239000002435 venom Substances 0.000 description 1
- 231100000611 venom Toxicity 0.000 description 1
- 210000001048 venom Anatomy 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses an anti-tumor medicine which mainly comprises scirpus fluviatilis, Caulis Spatholobi, Slender Dutchmanspipe Root, Astragalus membranaceus, Sculellaria barbata, Valeriana jatamansi Jones, hericium erinaceus, leech, Chinese blister beetle, pillworm, scarab, centipede, prepared turtle shell and dried toad skin. The medicine disclosed by the invention is complete in formula, brings out the best in each other and supports body resistance, repairs histocyte regeneration, reveres diseased cells to normal cells, and can effectively treat benign tumor. The traditional Chinese medicine is convenient to prepare and use, safe and free from toxic and side effects, so that the anti-tumor traditional Chinese medicine troche is an ideal anti-tumor medicine.
Description
Technical field
The invention discloses a kind of Chinese medicinal tablet, especially antineoplastic Chinese medicinal tablet and preparation method thereof.The invention belongs to the Chinese medicine field.
Background technology
Tumor (Tumor) be body under various carcinogenic factor effects, some cells of local organization lose the normal regulation to its growth on gene level, cause its clonal abnormality hypertrophy and the abnormality that forms.Educational circles generally is divided into tumor optimum and pernicious two large classes.
Swollen neoplastic reason: the characteristic of our Chinese medical is that existing doctor trained in Western medicine has again the traditional Chinese medical science.Sickness rate is high now, China's case load is quite huge, there is data to show that 55%. tumors that account for whole world case load are that the all-environment and hereditary carcinogenic factor of gene glass causes the DNA infringement with collaborative or sequential mode in itself, thereby activate proto-oncogene and (or) the deactivation tumor suppressor gene, add the apoptosis regulator gene and (or) change of DNA-repair gene, then cause the abnormal of expression, target cell is transformed.The cell that is converted first is the hypertrophy of clone's property more, through a very long multistage evolution process, one of them clones relatively unconfined amplification, pass through addition mutation, optionally form the sub-clone (heterogeneousization) with different characteristics, thereby obtain the ability (vicious transformation) that infiltrates and shift, form malignant tumor.
(1) number of tumor and size: the number of tumor, not of uniform size.Mostly be one, sometimes also can be a plurality of.The size of tumor and the character of tumor (optimum, pernicious), growth time and happening part have certain relation.Grow in body surface or larger endoceliac tumor can be grown very greatly sometimes, and the tumor that grows in airtight narrow and small tract is generally less.The very big person of tumor, poor growth, mostly be optimum usually; Malignant growth is rapid, can bring adverse consequences in a short time, and is therefore normal childlike.
(2) shape of tumor: the shape of tumor is varied, and polypoid (exophytic growth), mamillary (exophytic growth), nodositas (expansive growth), lobulated (expansive growth), cryptomere (expansive growth), wellability enclosed mass shape (infiltrative growth), the plump shape (external companion's infiltrative growth) of diffusivity, ulcer shape companion infiltrative growth are arranged.Difference in shape and its happening part, tissue-derived, growth pattern and tumor good pernicious closely related.Show according to recent experiment both at home and abroad, negative aeroion has inhibitory action to the growth of transplanted tumor.
(3) color of tumor: the tangent plane of general tumor is greyish white or bois de rose, depending on its contain blood volume number, have or not hemorrhage, degeneration, necrosis etc.Some tumor can present different colors because it contains pigment.Therefore can be inferred as according to the color of tumor which kind of tumor.Be yellow as lipoma, malignant melanoma is black, and hemangioma takes on a red color or kermesinus.
(4) hardness of tumor: with the ratio of the essence of the kind of tumor, tumor and a matter and have or not degeneration, downright bad relevant.Essence is generally softer more than the tumor of a matter; On the contrary, a matter is generally harder more than the tumor of essence.Softer when tumor tissue necroses, calcification occurs or harder when ossified.Lipoma is very soft, and osteoma is very hard.
In existing antineoplastic method, the patent No. 201210086706.5 discloses a kind of " a kind of anti-tumor drug " by name, by Radix Codonopsis, Fructus Ligustri Lucidi, Pericarpium Citri tangerinae, Flos Chrysanthemi, Rhizoma Paridis, Herba Taraxaci, Herba Patriniae, Periostracum Serpentis, Herba Schizonepetae, Flos Carthami, Herba Potentillae Discoloris, Fructus Forsythiae are that raw material is made, and main dosage form is capsule,, for the effect of anticancer and not as the tablet ideal, can cause to patient's health extra burden.
Although the medicine that provides in prior art more or less all has some curative effects on antitumor, the part prescription brings certain toxic and side effects more or less can for patient's gastrointestinal, Liver and kidney.Generally speaking, treatment there is no desirable definite treatment by Chinese herbs medicine for antineoplastic at present.
Summary of the invention
Present situation for existing antitumor deficiency, one of purpose of the present invention is to provide the antineoplastic Chinese medicinal tablet, have and prepare simple, taking convenience, easy to carry, the obvious characteristics of action effect, this Chinese medicinal tablet has repair tissue cell regeneration, reverses the normal effect of sick cell, and it adopts comparatively common in the localities Chinese crude drug as raw material, and is with low cost.
Another object of the present invention just is to provide the preparation method of above-mentioned Chinese medicinal tablet.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The anti-tumor Chinese medicine tablet, take off the primary raw material of stating weight proportion and be prepared from: rhizoma sparganic 15-25 part, Caulis Spatholobi 15-25 part, Radix Aristolochiae 15-25 part, Radix Astragali 20-30 part, Herba Scutellariae Barbatae 20-30 part, Rhizoma valerianae latifoliae 30-40 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 50-150 part, Hirudo 1-5 part, Mylabris 1-5 part, Armadillidium 1-5 part, go-cart worm 1-5 part, Scolopendra 1-5 part, Carapax Trionycis (processed) 1-5 part, dry maxima skin 1-5 part.
The anti-tumor Chinese medicine tablet, preferred proportioning, take off the primary raw material of stating weight proportion and be prepared from: rhizoma sparganic 18-23 part, Caulis Spatholobi 18-23 part, Radix Aristolochiae 18-23 part, Radix Astragali 23-28 part, Herba Scutellariae Barbatae 23-28 part, Rhizoma valerianae latifoliae 33-38 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 80-120 part, Hirudo 2-4 part, Mylabris 2-4 part, Armadillidium 2-4 part, go-cart worm 2-4 part, Scolopendra 2-4 part, Carapax Trionycis (processed) 2-4 part, dry maxima skin 2-4 part.
The anti-tumor Chinese medicine tablet, better preferred proportioning, take off the primary raw material of stating weight proportion and be prepared from: 20 parts of rhizoma sparganic, 20 parts of Caulis Spatholobis, 20 parts of Radix Aristolochiaes, 25 parts of the Radixs Astragali, 25 parts of Herba Scutellariae Barbataes, 35 parts of Rhizoma valerianae latifoliaes, 100 parts of Hericium erinaceus (Bull. Ex Fr.) Pers.es, 3 parts of Hirudos, 3 parts of Mylabris, 3 parts of Armadillidiums, 3 parts of go-cart worms, 3 parts of Scolopendras, 3 parts of Carapax Trionycis (processed)s, 3 parts of dry maxima skins.
The preparation method of above-mentioned Chinese medicinal tablet, preparation process is as follows:
(1) rhizoma sparganic, Caulis Spatholobi, Radix Aristolochiae, the Radix Astragali, Herba Scutellariae Barbatae, Rhizoma valerianae latifoliae, Hericium erinaceus (Bull. Ex Fr.) Pers. are pulverized, cross the 80-120 mesh sieve, obtain fine powder;
(2) Carapax Trionycis (processed) and dry maxima skin are soaked 20-40 minute fully with vinegar, taking-up is dried, and obtains vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed;
(3) Hirudo, Mylabris, Armadillidium, go-cart worm, Scolopendra, vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed are ground into fine powder, cross 120-140 mesh sieve (preferred 130);
(4) with step (3) gained fine powder mix homogeneously, to soak 2 hours with the cold water that temperature is preferred 30 ℃, water consumption is 3-4 times (preferred 3.5 times) of described fine powder weight;
(5) step (4) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume obtains concentrated solution;
(6) gained fine powder in step (1) is poured in the concentrated solution of step (5) gained, fully stirred into thick paste; Thick paste being dried by the fire 1-2 hour, obtain the oven dry thing, is dry under 70-90 ℃ in temperature;
(7) with step (6) gains according to 0.3-0.7g/ sheet metering, be pressed into circular or other forms of lamellar dosage form according to the preparation for processing of tablet.
The preparation method of above-mentioned Chinese medicinal tablet, preferred scheme is: step (1) is crossed 90-110 mesh sieve (preferred 100 mesh sieves).
The preparation method of above-mentioned Chinese medicinal tablet, preferred scheme is: step (2) is soaked 25-35 minute (preferred 30 minutes).
The preparation method of above-mentioned Chinese medicinal tablet, preferred scheme is: 1.3-1.8 hour (preferred 1.5 hours) of step (6) baking.
The preparation method of above-mentioned Chinese medicinal tablet, preferred scheme is: step (6) baking temperature is 75-85 ℃ (preferred 80 ℃).
The preparation method of above-mentioned Chinese medicinal tablet, preferred scheme is: the specification of step (7) tablet is 0.4-0.6g/ sheet (preferred 0.5g).
Using method: reach optimum therapeuticing effect for making the present invention, when edible, take after 1 hour after the meal, use warm boiled water, 3 times on the one, each 3 grams.
This Chinese medicinal tablet is remarkable to the opposing tumor effect, each is organized medicine and complements each other, both helped the absorption running of medicine, anti-all medicines are sweet stagnant cool cold again, can mend the gas of strengthening spleen and lung, invigorating spleen to remove dampness, again can heat-clearing and toxic substances removing, repair tissue cell regeneration, reverse sick cell normal, finally reach anticancer purpose, long-term taking can play good therapeutical effect to tumor.
The anti-tumor Chinese medicine tablet, the pharmacological effect of each crude drug is respectively:
Rhizoma sparganic: flavor efficacy: bitter in the mouth, property is flat.Removing blood stasis, circulation of qi promoting, removing food stagnancy pain relieving.Clinical practice: be applicable to kinds of tumors, as ovarian cancer, cervical cancer, hepatocarcinoma etc.Normal and the ovarian cancer that compatibility treatment QI and blood knot amasss, the blood stasis stasis of blood is stagnant, the cervical cancers etc. such as Rhizoma Cyperi, Rhizoma Curcumae, Radix Arnebiae (Radix Lithospermi), Fructus Fici Pumilae.The hepatocarcinoma that compatibility treatment qi depression to blood stasis, the pyretic toxicity such as Herba Hedyotidis Diffusae commonly used, Pericarpium Arecae, Poria, Rhizoma Curcumae pent up.These product also are applicable to stagnation of QI and blood, abdominal part caking, hepatosplenomegaly, amenorrhea stomachache, food stagnation distending pain etc. in addition.
Caulis Spatholobi: bitter, sweet, temperature.Return liver, kidney channel.Relaxing muscles and tendons to promote blood circulation; Nourishing blood for regulating menstruation.Main numb hand and foot; Quadriplegia; Rheumatic arthralgia; The women has through uncomfortable; Dysmenorrhea; Amenorrhea.Enrich blood, invigorate blood circulation, collateral dredging.Be used for menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.
Radix Aristolochiae: Radix Aristolochiae is the stem of Radix Cocculi Orbiculati, Radix Cocculi Orbiculati another name: lead a cow in Radix Aristolochiae, Ma Geluo, little Herba Ophioglossi, Cortex Ampelopsis Aconitifoliae Radicis, burst rattan, the same rattan of family, open country, hair Radix seu Caulis fici Martinii, slabstone rattan, mouse rattan, Radix seu Caulis fici Martinii, shallow bid rattan, cattle string, bitter in the mouth, and property is put down.The function expelling wind and removing dampness; The regulating QI pain relieving; Inducing diuresis to remove edema.Cure mainly rheumatic arthralgia; Traumatic injury; Stomachache; Stomachache; Edema; Stranguria.
The Radix Astragali: sweet, tepor.Gui Jing: return lung, spleen, liver, kidney channel.The Radix Astragali has benefiting QI for strengthening the superficies, arresting sweating admittedly to take off, hold in the palm the effect of skin ulcer granulation promoting, inducing diuresis to remove edema.Be used for the treatment of the deficiency of vital energy weak, sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.The invigorating middle warmer of Radix Astragali Preparata QI invigorating, give birth to consolidating superficial resistance holder skin ulcer.
Herba Scutellariae Barbatae: hot, bitter, cold.Return lung, liver, kidney channel.Heat-clearing and toxic substances removing, the blood stasis dispelling diuresis.Be used for furuncle swelling toxin, laryngopharynx swelling and pain, venom, fall and flutter the pain of injury, edema, jaundice.
Rhizoma valerianae latifoliae: acrid in the mouth; Little hardship; Warm in nature.Regulating the flow of Qi and the middle Jiao, dispelling cold and removing dampness; Promoting blood circulation and detumescence.Main abdominal distention; Tell and have loose bowels; Infantile malnutrition; Anemofrigid-damp arthralgia; The limb air water is swollen; Menoxenia; Traumatic injury; Furuncle.
Hericium erinaceus (Bull. Ex Fr.) Pers.: antiulcer and antiinflammatory action.Antitumor action.Liver protection function, increase immunity, anti-aging effects.Improve body's hypoxia tolerance, increase the heart blood output, accelerate the body blood circulation.Reduce the effect of blood glucose and blood fat.
Hirudo: salty hardship, flat, poisonous.Have that treatment menstruation apolipsis, lump in the abdomen stomachache, blood-retention, traumatic blood stasis are had a pain, the effect of carbuncle erysipelas.
Mylabris: acrid in the mouth; Warm in nature; Poisonous.The counteracting toxic substances phagedenoma; The removing blood stasis eliminating stagnation.Main carbuncle; Scrofula; Stubborn dermatitis; Amenorrhea; Lump in the abdomen; Cancerous protuberance.Yong Yu WEIJIA lump, stubborn dermatitis for many years, scrofula, wart, carbuncle are not burst, the dead flesh of malignant boil.
Armadillidium: acid, temperature, nontoxic.Be used for relieving sore throat and pain, the removing blood stasis with potent drugs diuretic.Removing blood stasis, diuretic, detoxifcation, pain relieving.Control the chronic malaria malaria with splenomegaly, amenorrhea lump in the abdomen, urinary obstruction, infantile convulsion locked jaw, ability to speak pain, all skin ulcers of thrush.1. " herbal classic ": " main stranguria due to disorder of QI dysuria, the married woman closes abdominal mass due to blood stasis the moon, Xian, Chi, cold and heat, dredging water passages." 2. " Japan hanako materia medica ": " diuresis can be had an abortion." 3. " detailed outline ": control the chronic malaria cold and heat, wind dental caries tooth pain, children's's locked jaw infantile convulsion, thrush, variola are fallen dimple, and solution is penetrated the work poison, spider venom, scutige is pleasant.4. " it is former that book on Chinese herbal medicine is asked ": the main cold and heat stasis of blood is long-pending, damp-phlegm, larynx disease, infantile convulsion, disorders of blood, dyspnea with rapid respiration.
Go-cart worm: salty, cold, poisonous.Arresting convulsion, removing blood stasis with potent drugs, relieving constipation, counteracting toxic substances.Control infantile convulsion, demented, lump in the abdomen, dysphagia and regurgitation, the abdominal distention constipation, gonorrhea, infantile malnutrition, dysentery, anal fistula, furuncle is swollen, malignant boil.
Scolopendra: can make the soft contracting of lump, pressure symptom is alleviated, and can make the transference cures such as distending pain, and ulcer is calmed down, and the state of an illness significantly takes a turn for the better.
Carapax Trionycis (processed): salty, cold.Return liver, kidney channel.Can suppress the connective tissue proliferation of liver, spleen, improve the plasma protein level, reach the effects such as antitumor.
Dry maxima skin: heat-clearing and toxic substances removing, diuretic relieving distension.Control carbuncle, toxic swelling, scrofula, tumor, infantile malnutrition abdominal distention, chronic tracheitis
Chinese medicinal tablet of the present invention is based on Chinese medicine antineoplastic principle.The Chinese medicinal material of selecting all has blood circulation promoting and blood stasis dispelling, the body resistance strengthening and constitution consolidating, and repair tissue cell regeneration, reverse the normal effect of sick cell, and in addition, excellent results of the present invention also shows:
1,This prescription meets Chinese medicine principle and tumor patient body and mind characteristics fully, under the prerequisite of general principle, can different prescriptions be arranged according to different crowd, and function is different.
2,The medicine source is easy to get, and medical material is with low cost, can relieve patient ' s burden.
The specific embodiment
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1The antineoplastic Chinese medicinal tablet, take off the primary raw material of stating weight proportion and be prepared from: rhizoma sparganic 15 grams, Caulis Spatholobi 15 grams, Radix Aristolochiae 15 grams, the Radix Astragali 20 grams, Herba Scutellariae Barbatae 20 grams, Rhizoma valerianae latifoliae 30 grams, Hericium erinaceus (Bull. Ex Fr.) Pers. 50 grams, Hirudo 1 gram, Mylabris 1 gram, Armadillidium 1 gram, go-cart worm 1 gram, Scolopendra 1 gram, Carapax Trionycis (processed) 1 gram, dry maxima skin 1 gram.
The preparation method of above-mentioned Chinese medicinal tablet, step is:
(1) rhizoma sparganic, Caulis Spatholobi, Radix Aristolochiae, the Radix Astragali, Herba Scutellariae Barbatae, Rhizoma valerianae latifoliae, Hericium erinaceus (Bull. Ex Fr.) Pers. are pulverized, cross 80 mesh sieves, obtain fine powder;
(2) Carapax Trionycis (processed) and dry maxima skin were soaked 20 minutes fully with vinegar, taking-up is dried, and obtains vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed;
(3) Hirudo, Mylabris, Armadillidium, go-cart worm, Scolopendra, vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed are ground into fine powder, cross 120 mesh sieves;
(4) with step (3) gained fine powder mix homogeneously, to soak 2 hours with the cold water that temperature is preferred 30 ℃, water consumption is 3 of described fine powder weight;
(5) step (4) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume obtains concentrated solution;
(6) gained fine powder in step (1) is poured in the concentrated solution of step (5) gained, fully stirred into thick paste; With thick paste baking 1, obtain the oven dry thing, be 70 in temperature;
(7) with step (6) gains according to 0.3g/ sheet metering, be pressed into circular or other forms of lamellar dosage form according to the preparation for processing of tablet.
Embodiment 2The antineoplastic Chinese medicinal tablet, take off the primary raw material of stating weight proportion and be prepared from: rhizoma sparganic 25 grams, Caulis Spatholobi 25 grams, Radix Aristolochiae 25 grams, the Radix Astragali 30 grams, Herba Scutellariae Barbatae 30 grams, Rhizoma valerianae latifoliae 40 grams, Hericium erinaceus (Bull. Ex Fr.) Pers. 150 grams, Hirudo 5 grams, Mylabris 5 grams, Armadillidium 5 grams, go-cart worm 5 grams, Scolopendra 5 grams, Carapax Trionycis (processed) 5 grams, dry maxima skin 5 grams.
The preparation method of above-mentioned Chinese medicinal tablet, step is:
(1) rhizoma sparganic, Caulis Spatholobi, Radix Aristolochiae, the Radix Astragali, Herba Scutellariae Barbatae, Rhizoma valerianae latifoliae, Hericium erinaceus (Bull. Ex Fr.) Pers. are pulverized, cross 120 mesh sieves, obtain fine powder;
(2) Carapax Trionycis (processed) and dry maxima skin were soaked 40 minutes fully with vinegar, taking-up is dried, and obtains vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed;
(3) Hirudo, Mylabris, Armadillidium, go-cart worm, Scolopendra, vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed are ground into fine powder, cross 140 mesh sieves;
(4) with step (3) gained fine powder mix homogeneously, to soak 2 hours with the cold water that temperature is preferred 30 ℃, water consumption is 4 times of described fine powder weight;
(5) step (4) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume obtains concentrated solution;
(6) gained fine powder in step (1) is poured in the concentrated solution of step (5) gained, fully stirred into thick paste; With thick paste baking 2 hours, obtain the oven dry thing, be dry under 90 ℃ in temperature;
(7) with step (6) gains according to 0.7g/ sheet metering, be pressed into circular or other forms of lamellar dosage form according to the preparation for processing of tablet.
Embodiment 3The antineoplastic Chinese medicinal tablet, take off the primary raw material of stating weight proportion and be prepared from: rhizoma sparganic 18 grams, Caulis Spatholobi 18 grams, 18 parts of Radix Aristolochiaes, 23 parts of the Radixs Astragali, 23 parts of Herba Scutellariae Barbataes, 33 parts of Rhizoma valerianae latifoliaes, 80 parts of Hericium erinaceus (Bull. Ex Fr.) Pers.es, 2 parts of Hirudos, 2 parts of Mylabris, 2 parts of Armadillidiums, 2 parts of go-cart worms, 2 parts of Scolopendras, 2 parts of Carapax Trionycis (processed)s, 2 parts of dry maxima skins.
The preparation method of above-mentioned Chinese medicinal tablet, step is:
(1) rhizoma sparganic, Caulis Spatholobi, Radix Aristolochiae, the Radix Astragali, Herba Scutellariae Barbatae, Rhizoma valerianae latifoliae, Hericium erinaceus (Bull. Ex Fr.) Pers. are pulverized, cross 90 mesh sieves, obtain fine powder;
(2) Carapax Trionycis (processed) and dry maxima skin were soaked 25 minutes fully with vinegar, taking-up is dried, and obtains vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed;
(3) Hirudo, Mylabris, Armadillidium, go-cart worm, Scolopendra, vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed are ground into fine powder, cross 125 mesh sieves;
(4) with step (3) gained fine powder mix homogeneously, to soak 2 hours with the cold water that temperature is preferred 30 ℃, water consumption is 3.3 times of described fine powder weight;
(5) step (4) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume obtains concentrated solution;
(6) gained fine powder in step (1) is poured in the concentrated solution of step (5) gained, fully stirred into thick paste; With thick paste baking 1.3 hours, obtain the oven dry thing, be dry under 75 ℃ in temperature;
(7) with step (6) gains according to 0.4g/ sheet metering, be pressed into circular or other forms of lamellar dosage form according to the preparation for processing of tablet.
Embodiment 4The antineoplastic Chinese medicinal tablet, take off the primary raw material of stating weight proportion and be prepared from: rhizoma sparganic 23 grams, Caulis Spatholobi 23 grams, Radix Aristolochiae 23 grams, the Radix Astragali 28 grams, Herba Scutellariae Barbatae 28 grams, Rhizoma valerianae latifoliae 38 grams, Hericium erinaceus (Bull. Ex Fr.) Pers. 120 grams, Hirudo 4 grams, Mylabris 4 grams, Armadillidium 4 grams, go-cart worm 4 grams, Scolopendra 4 grams, Carapax Trionycis (processed) 4 grams, dry maxima skin 4 grams.
The preparation method of above-mentioned Chinese medicinal tablet, step is:
(1) rhizoma sparganic, Caulis Spatholobi, Radix Aristolochiae, the Radix Astragali, Herba Scutellariae Barbatae, Rhizoma valerianae latifoliae, Hericium erinaceus (Bull. Ex Fr.) Pers. are pulverized, cross 110 mesh sieves, obtain fine powder;
(2) Carapax Trionycis (processed) and dry maxima skin were soaked 35 minutes fully with vinegar, taking-up is dried, and obtains vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed;
(3) Hirudo, Mylabris, Armadillidium, go-cart worm, Scolopendra, vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed are ground into fine powder, cross 135 mesh sieves;
(4) with step (3) gained fine powder mix homogeneously, to soak 2 hours with the cold water that temperature is preferred 30 ℃, water consumption is 3.8 times of described fine powder weight;
(5) step (4) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume obtains concentrated solution;
(6) gained fine powder in step (1) is poured in the concentrated solution of step (5) gained, fully stirred into thick paste; With thick paste baking 1.8 hours, obtain the oven dry thing, be dry under 85 ℃ in temperature;
(7) with step (6) gains according to 0.6g/ sheet metering, be pressed into circular or other forms of lamellar dosage form according to the preparation for processing of tablet.
Embodiment 5:The antineoplastic Chinese medicinal tablet, take off the primary raw material of stating weight proportion and be prepared from: rhizoma sparganic 20 grams, Caulis Spatholobi 20 grams, Radix Aristolochiae 20 grams, the Radix Astragali 25 grams, Herba Scutellariae Barbatae 25 grams, Rhizoma valerianae latifoliae 35 grams, Hericium erinaceus (Bull. Ex Fr.) Pers. 100 grams, Hirudo 3 grams, Mylabris 3 grams, Armadillidium 3 grams, go-cart worm 3 grams, Scolopendra 3 grams, Carapax Trionycis (processed) 3 grams, dry maxima skin 3 grams.
(1) rhizoma sparganic, Caulis Spatholobi, Radix Aristolochiae, the Radix Astragali, Herba Scutellariae Barbatae, Rhizoma valerianae latifoliae, Hericium erinaceus (Bull. Ex Fr.) Pers. are pulverized, cross 100 mesh sieves, obtain fine powder;
(2) Carapax Trionycis (processed) and dry maxima skin were soaked 30 minutes fully with vinegar, taking-up is dried, and obtains vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed;
(3) Eupolyphaga Seu Steleophaga, Hirudo, Mylabris, Armadillidium, go-cart worm, Scolopendra, vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed are ground into fine powder, cross 130 mesh sieves;
(4) with step (3) gained fine powder mix homogeneously, to soak 2 hours with the cold water that temperature is preferred 30 ℃, water consumption is 3.5 times of described fine powder weight;
(5) step (4) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume obtains concentrated solution;
(6) gained fine powder in step (1) is poured in the concentrated solution of step (5) gained, fully stirred into thick paste; With thick paste baking 1.5 hours, obtain the oven dry thing, be dry under 80 ℃ in temperature;
(7) with step (6) gains according to 0.5g/ sheet metering, be pressed into circular or other forms of lamellar dosage form according to the preparation for processing of tablet.
Using method: reach optimum therapeuticing effect for making the present invention, when edible, take after 1 hour after the meal, use warm boiled water, 3 times on the one, each 10 grams.
Experimental example:Purpose is to verify whether this Chinese medicinal tablet has curative effect to antitumor.
" the new Chinese medicine guideline of clinical investigations " formulated according to Ministry of Public Health 1993 is diagnosis basis, totally 200 routine tumor patients, and the mean age is 45 years old.Random division is administration group and matched group.
The previous day before experiment, record patient's health, look over the patient body symptom every day, guarantee that administration group and matched group situation are basically identical.Administration group edible this product embodiments 5 gained Chinese medicinal tablets every day, 10 days is a course for the treatment of.Check the patient body situation every day, make a record.Result such as following table 1:
Table 1:
Self-induction symptom and emotion changes result such as table 2:
Table 2:
?When administration group (Chinese medicinal tablet of the present invention) is used 10 days, the most patient sensory symptoms obviously alleviates, obviously feel to take a favorable turn in affected part, patient's emotion takes a turn for the better, medication in the time of 20 days patient substantially painless, obviously sensation tumor deliquescing, drug withdrawal a period of time has no repeatedly, and the state of an illness is better controlled, and tumor is without diffusion.The matched group rear curative effect of taking medicine is obvious, but after drug withdrawal, 94% patient is recurred again.
Prove through clinical trial, Chinese medicinal tablet of the present invention is on antitumor, and effective percentage is 97%, and cure rate is 91%, than oral western medicine effective percentage, exceeds 18%, and cure rate exceeds 62%, makes the patient feel that really tumor is controlled; And can not cause to patient's health any burden.Chinese medicinal tablet instant effect of the present invention, can reach the purpose of rapid alleviation patient misery, and relapse rate is low, is a kind of Chinese medicinal tablet of antineoplastic safely and effectively.
Claims (9)
1. the antineoplastic Chinese medicinal tablet, is characterized in that: take off the primary raw material of stating weight proportion and be prepared from: rhizoma sparganic 15-25 part, Caulis Spatholobi 15-25 part, Radix Aristolochiae 15-25 part, Radix Astragali 20-30 part, Herba Scutellariae Barbatae 20-30 part, Rhizoma valerianae latifoliae 30-40 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 50-150 part, Hirudo 1-5 part, Mylabris 1-5 part, Armadillidium 1-5 part, go-cart worm 1-5 part, Scolopendra 1-5 part, Carapax Trionycis (processed) 1-5 part, dry maxima skin 1-5 part.
2. Chinese medicinal tablet according to claim 1, is characterized in that: take off the primary raw material of stating weight proportion and be prepared from: rhizoma sparganic 18-23 part, Caulis Spatholobi 18-23 part, Radix Aristolochiae 18-23 part, Radix Astragali 23-28 part, Herba Scutellariae Barbatae 23-28 part, Rhizoma valerianae latifoliae 33-38 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 80-120 part, Hirudo 2-4 part, Mylabris 2-4 part, Armadillidium 2-4 part, go-cart worm 2-4 part, Scolopendra 2-4 part, Carapax Trionycis (processed) 2-4 part, dry maxima skin 2-4 part.
3. Chinese medicinal tablet according to claim 1, is characterized in that: take off the primary raw material of stating weight proportion and be prepared from: 20 parts of rhizoma sparganic, 20 parts of Caulis Spatholobis, 20 parts of Radix Aristolochiaes, 25 parts of the Radixs Astragali, 25 parts of Herba Scutellariae Barbataes, 35 parts of Rhizoma valerianae latifoliaes, 100 parts of Hericium erinaceus (Bull. Ex Fr.) Pers.es, 3 parts of Hirudos, 3 parts of Mylabris, 3 parts of Armadillidiums, 3 parts of go-cart worms, 3 parts of Scolopendras, 3 parts of Carapax Trionycis (processed)s, 3 parts of dry maxima skins.
4. the preparation method of according to claim 1-3 arbitrary described Chinese medicinal tablets, is characterized in that, step is as follows:
(1) rhizoma sparganic, Caulis Spatholobi, Radix Aristolochiae, the Radix Astragali, Herba Scutellariae Barbatae, Rhizoma valerianae latifoliae, Hericium erinaceus (Bull. Ex Fr.) Pers. are pulverized, cross the 80-120 mesh sieve, obtain fine powder;
(2) Carapax Trionycis (processed) and dry maxima skin are soaked 20-40 minute fully with vinegar, taking-up is dried, and obtains vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed;
(3) Hirudo, Mylabris, Armadillidium, go-cart worm, Scolopendra, vinegar Carapax Trionycis (processed) processed and vinegar dry maxima skin processed are ground into fine powder, cross 120-140 mesh sieve (preferred 130 mesh sieves);
(4) with step (3) gained fine powder mix homogeneously, to soak 2 hours with the cold water that temperature is preferred 30 ℃, water consumption is 3-4 times (preferred 3.5 times) of described fine powder weight;
(5) step (4) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume obtains concentrated solution;
(6) gained fine powder in step (1) is poured in the concentrated solution of step (5) gained, fully stirred into thick paste; Thick paste being dried by the fire 1-2 hour, obtain the oven dry thing, is dry under 70-90 ℃ in temperature;
(7) with step (6) gains according to 0.3-0.7g/ sheet metering, be pressed into circular or other forms of lamellar dosage form according to the preparation for processing of tablet.
5. preparation method according to claim 4, is characterized in that: step (1) mistake 90-110 mesh sieve (preferred 100 mesh sieves).
6. preparation method according to claim 4, is characterized in that: 25-35 minute (preferred 30 minutes) of step (2) immersion.
7. preparation method according to claim 4, is characterized in that: 1.3-1.8 hour (preferred 1.5 hours) of step (6) baking.
8. preparation method according to claim 4, it is characterized in that: step (6) baking temperature is 75-85 ℃ (preferred 80 ℃).
9. preparation method according to claim 4, it is characterized in that: the specification of step (7) tablet is the preferred 0.5g of 0.4-0.6g().
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310318954.2A CN103386056B (en) | 2013-07-27 | 2013-07-27 | Anti-tumor traditional Chinese medicine troche and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310318954.2A CN103386056B (en) | 2013-07-27 | 2013-07-27 | Anti-tumor traditional Chinese medicine troche and preparation method thereof |
Related Child Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410482816.2A Division CN104208538A (en) | 2013-07-27 | 2013-07-27 | Antitumor traditional Chinese medicine preparation and preparation method thereof |
| CN201410482817.7A Division CN104225395A (en) | 2013-07-27 | 2013-07-27 | Tumor-resistant traditional Chinese medicine and preparation method |
| CN201410482707.0A Division CN104208537A (en) | 2013-07-27 | 2013-07-27 | Method for preparing antitumor traditional Chinese medicine |
| CN201410482910.8A Division CN104208539A (en) | 2013-07-27 | 2013-07-27 | Method for preparing antitumor traditional Chinese medicine tablets |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103386056A true CN103386056A (en) | 2013-11-13 |
| CN103386056B CN103386056B (en) | 2014-11-26 |
Family
ID=49530590
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310318954.2A Active CN103386056B (en) | 2013-07-27 | 2013-07-27 | Anti-tumor traditional Chinese medicine troche and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103386056B (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101049484A (en) * | 2007-05-14 | 2007-10-10 | 郝来勤 | Strong effective Chinese traditional medicine for treating lung cancer and other various cancers |
| CN101670071A (en) * | 2009-09-25 | 2010-03-17 | 卢速江 | Traditional Chinese medicine preparation for treating cancer and preparation method thereof |
| CN102772745A (en) * | 2012-08-21 | 2012-11-14 | 卢速江 | Chinese medicinal preparation for treating cancer and preparation method thereof |
-
2013
- 2013-07-27 CN CN201310318954.2A patent/CN103386056B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101049484A (en) * | 2007-05-14 | 2007-10-10 | 郝来勤 | Strong effective Chinese traditional medicine for treating lung cancer and other various cancers |
| CN101670071A (en) * | 2009-09-25 | 2010-03-17 | 卢速江 | Traditional Chinese medicine preparation for treating cancer and preparation method thereof |
| CN102772745A (en) * | 2012-08-21 | 2012-11-14 | 卢速江 | Chinese medicinal preparation for treating cancer and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 南京中医药大学: "《中药大辞典》", 31 March 2006, article "《斑蝥》" * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103386056B (en) | 2014-11-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106474418A (en) | For treating Chinese medicine composition of gastropathy and preparation method thereof | |
| CN103432532A (en) | Traditional Chinese medicine granules for treating nodules of breast and preparation method thereof | |
| CN104189783A (en) | Traditional Chinese medicine for treating oral ulcer | |
| CN104043057A (en) | Traditional Chinese medicinal composition for treating lymph cancer | |
| CN103977366A (en) | Medicine for treating chronic cholecystitis | |
| CN103920034A (en) | Traditional Chinese medicine composition for alleviating side effects of chemotherapy of cancer patient and preparation method traditional Chinese medicine composition | |
| CN104225395A (en) | Tumor-resistant traditional Chinese medicine and preparation method | |
| CN104491716A (en) | Traditional Chinese medicine capsule for treating lymphoma and preparation method of traditional Chinese medicine capsule | |
| CN104398733B (en) | A kind of Chinese medicine preparation for treating caused by hepatic stagnation qi stagnation thyroid cancer | |
| CN103386056B (en) | Anti-tumor traditional Chinese medicine troche and preparation method thereof | |
| CN106266961A (en) | A kind of Chinese medicine composition of the spleen-stomach disease and gastroenteropathy Comprehensive Treatment and preparation method thereof | |
| CN102139032A (en) | Traditional Chinese medicine for treating intervertebral disc protrusion, hyperosteogeny and rheumatoid disease | |
| CN104958735A (en) | Traditional Chinese medicine for treating rheumatic arthritis | |
| CN104547553A (en) | Traditional Chinese medicine for treating nervous endocrine disorder | |
| CN103990019A (en) | Traditional Chinese medicine preparation for treating light-headedness | |
| CN104398975A (en) | Traditional Chinese medicinal preparation for treating fibroadenoma of breast and preparation method thereof | |
| CN104352970A (en) | Traditional Chinese medicine preparation for treating cystic hyperplasia of mammary glands | |
| CN103908616A (en) | Medicament for relieving radiation side reactions of cancer patients and preparation method thereof | |
| CN104208539A (en) | Method for preparing antitumor traditional Chinese medicine tablets | |
| CN104208538A (en) | Antitumor traditional Chinese medicine preparation and preparation method thereof | |
| CN104208537A (en) | Method for preparing antitumor traditional Chinese medicine | |
| CN106389598A (en) | Traditional Chinese medicine composition for curing purpura | |
| CN105456951A (en) | Traditional Chinese medicine preparation for treating breast fibroadenoma and preparing method of traditional Chinese medicine preparation | |
| CN105687474A (en) | Preparation for cancer patient to take during chemotherapy period and preparation method | |
| CN104721786A (en) | Traditional Chinese medicine preparation for treating intrahepatic cholestasis of pregnancy and preparation method of traditional Chinese medicine preparation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| ASS | Succession or assignment of patent right |
Owner name: LIU YING Free format text: FORMER OWNER: GUO XIANGRONG Effective date: 20141009 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| C53 | Correction of patent of invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Liu Ying Inventor after: Yang Zhi Inventor after: Liu Wenming Inventor after: Xu Fang Inventor after: Jia Zhongming Inventor before: Guo Xiangrong Inventor before: Zhang Xiuhua Inventor before: Zhou Hua Inventor before: Du Xinhua |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: GUO XIANGRONG ZHANG XIUHUA ZHOU HUA DU XINHUA TO: LIU YING YANG ZHI LIU WENMING XU FANG JIA ZHONGMING Free format text: CORRECT: ADDRESS; FROM: 252000 LIAOCHENG, SHANDONG PROVINCE TO: 256600 BINZHOU, SHANDONG PROVINCE |
|
| TA01 | Transfer of patent application right |
Effective date of registration: 20141009 Address after: 256600, No. two, 661 the Yellow River Road, Bincheng District, Shandong, Binzhou Applicant after: Liu Ying Address before: 252000 No. 7, building 101, garden north road, Dongchangfu District, Shandong, Liaocheng, 206 Applicant before: Guo Xiangrong |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: HAIMEN JINQILIN ROSEWOOD INVESTMENT AND DEVELOPMEN Free format text: FORMER OWNER: LIU YING Effective date: 20150416 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 256600 BINZHOU, SHANDONG PROVINCE TO: 226100 NANTONG, JIANGSU PROVINCE |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20150416 Address after: 226100 Nantong, Haimen City, Haimen City, Hai Tong Road, No. 207 Patentee after: Haimen Jinqilin Rosewood Investment and Development Co., Ltd. Address before: 256600, No. two, 661 the Yellow River Road, Bincheng District, Shandong, Binzhou Patentee before: Liu Ying |