CN103385241A - Compound preservative and application thereof - Google Patents

Compound preservative and application thereof Download PDF

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Publication number
CN103385241A
CN103385241A CN2013103611286A CN201310361128A CN103385241A CN 103385241 A CN103385241 A CN 103385241A CN 2013103611286 A CN2013103611286 A CN 2013103611286A CN 201310361128 A CN201310361128 A CN 201310361128A CN 103385241 A CN103385241 A CN 103385241A
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China
Prior art keywords
hydroxybenzoate
preservative
compound preservative
solute
component
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CN2013103611286A
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Chinese (zh)
Inventor
白艳平
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GUANGZHOU BOJIA BIOLOGICAL SCIENCE & TECHNOLOGY Co Ltd
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GUANGZHOU BOJIA BIOLOGICAL SCIENCE & TECHNOLOGY Co Ltd
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Priority to CN2013103611286A priority Critical patent/CN103385241A/en
Publication of CN103385241A publication Critical patent/CN103385241A/en
Pending legal-status Critical Current

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  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention discloses a compound preservative and an application thereof and aims to provide one compound preservative which is simple in preparation method and is good in antiseptic and antibacterial properties. The preservative disclosed by the invention is used as an additive of a skin care product. The technical key points are as follows: the preservative is composed of a solute and phenoxyethanol in a mass ratio of 1 to 1, wherein the solute is composed of the following components in mass percentage: 1%-40% of methyl p-hydroxybenzoate, 1%-40% of ethyl p-hydroxybenzoate, 1%-20% of propyl p-hydroxybenzoate and 1%-15% of butyl p-hydroxybenzoate; the sum of all the components is 100. The invention provides the application of the compound preservative as the additive of the skin care product, belonging to the technical field of household chemicals.

Description

A kind of compound preservative and uses thereof
Technical field
The present invention discloses a kind of compound preservative, specifically, is a kind of compound preservative as the skin care item preservative, belongs to the daily chemical products technical field.
Background technology
Raising along with people's living standard, people are also more and more higher to the pursuit of quality of life, the skin care maintenance has become many problems of being concerned about, people are also higher to the quality requirement of various skin care item, the various skin care item that contain a large amount of natural organic matter compositions are repaired skin function preferably owing to having, and deeply are subjected to liking of people.But various to contain a large amount of natural organic matters higher to requirement for anticorrosion.On market, various preservative component are more single, and the antiseptic and inhibiting bacteria function Performance Ratio is poor, the client is in the posterior segment of using product, owing to contacting with air for a long time, and bacterium on hand and Product mix, easily produce microbiological contamination, the situation such as rotten and affect the effect of product, this producer has brought certain puzzlement.
Summary of the invention
For the problems referred to above, the object of the present invention is to provide the compound preservative that a kind of preparation method is simple, anticorrosion, bacteriostasis property is good, the present invention also provides the purposes of this preservative as skin-care product additive.
For solving the problems of the technologies described above, last technical scheme provided by the invention is such: this compound preservative is comprised of solute and the Phenoxyethanol of mass ratio 1:1;
Wherein: described solute consists of the component of following mass percent: methyl p-hydroxybenzoate 1 ~ 40%, and ethyl-para-hydroxybenzoate 1 ~ 40%, propylparaben 1 ~ 20%, butyl p-hydroxybenzoate 1 ~ 15%, each component sum is 100%.
Further, above-mentioned a kind of compound preservative, be comprised of solute and the Phenoxyethanol of mass ratio 1:1;
Wherein: described solute consists of the component of following mass percent: methyl p-hydroxybenzoate 10-35%, and ethyl-para-hydroxybenzoate 10 ~ 35%, propylparaben 5 ~ 20%, butyl p-hydroxybenzoate 5 ~ 15%, each component sum is 100%.
After provided by the invention, a technical scheme is such: this compound preservative is as the purposes of skin-care product additive, particularly
As the purposes that contains the natural organic matter skin-care product additive.
Above-mentioned compound preservative is during as skin-care product additive, and described compound preservative accounts for 0.5% of skin care item gross mass.
Compared with prior art, technical scheme provided by the invention has following advantage:
1, the present invention, with four kinds of p-hydroxybenzoates (methyl p-hydroxybenzoate, ethyl-para-hydroxybenzoate, propylparaben, butyl p-hydroxybenzoate) of specific proportioning, can demonstrate best resistance effect to bacterium and mould in the PH scope widely; Effectively prevent the phenomenons such as going bad appears in skin care item during the course, microbiological contamination, thereby avoided the business economic loss of because of product, returning goods and causing, produced market and economic benefit significantly.
2, preservative provided by the invention is with the hydroxybenzoic acid ester admixture, liquid compound preservative take Phenoxyethanol as solvent, easy operating is 0.5% with the formula consumption that is formulated in each product in end product, based on this working concentration, each active matter content is all within Europe and the highest permission addition 0.8% of Japan and 1%.
3, technical scheme provided by the invention has the synergistic effect of mixture,, with single p-hydroxybenzoate Compound Phase ratio, still has better fungistatic effect when low concentration; Particularly to containing natural organic matter composition such as protein, be difficult to the corrosion-resistant personal care product effective especially.
4, p-hydroxybenzoate is present in natural plant and animal, and is biodegradable in environment, meets environmental requirement.
Embodiment
Below in conjunction with embodiment; claim of the present invention is described in further detail; but become not any limitation of the invention, the modification of anyone makes in the claims in the present invention scope limited number of time, still at claim protection domain of the present invention.
Embodiment 1
A kind of compound preservative, be comprised of 100g solute and 100g Phenoxyethanol; Described solute consists of the component of following mass percent: methyl p-hydroxybenzoate 25g, ethyl-para-hydroxybenzoate 40g, propylparaben 20g, butyl p-hydroxybenzoate 15g.
Embodiment 2
A kind of compound preservative, be comprised of 100g solute and 100g Phenoxyethanol; Described solute consists of the component of following mass percent: methyl p-hydroxybenzoate 40g, ethyl-para-hydroxybenzoate 25g, propylparaben 20g, butyl p-hydroxybenzoate 15g.
Embodiment 3
A kind of compound preservative, be comprised of 100g solute and 100g Phenoxyethanol; Described solute consists of the component of following mass percent: methyl p-hydroxybenzoate 30g, ethyl-para-hydroxybenzoate 30g, propylparaben 20g, butyl p-hydroxybenzoate 20g.
Embodiment 4
A kind of compound preservative, be comprised of 100g solute and 100g Phenoxyethanol; Described solute consists of the component of following mass percent: methyl p-hydroxybenzoate 35g, ethyl-para-hydroxybenzoate 35g, propylparaben 15g, butyl p-hydroxybenzoate 15g.
Embodiment 5
A kind of compound preservative, be comprised of 100g solute and 100g Phenoxyethanol; Described solute consists of the component of following mass percent: methyl p-hydroxybenzoate 20g, ethyl-para-hydroxybenzoate 40g, propylparaben 20g, butyl p-hydroxybenzoate 20g.
Its preparation method is: take each component, be added in solvent, stirring and dissolving gets final product; During interpolation, the preparation method of skin care item routinely, emulsifying forms.
For advantage of the present invention better is described, below provide this patent preservative and single methyl p-hydroxybenzoate, ethyl-para-hydroxybenzoate, propylparaben, the test microbiological data table of the minimum inhibitory concentration of butyl p-hydroxybenzoate (MIC).
Figure 827618DEST_PATH_IMAGE002
As can be seen from the above table: this patent preservative and single p-hydroxybenzoate Compound Phase ratio have better fungistatic effect when low concentration.P-hydroxybenzoate is present in natural plant and animal, and biodegradable in environment.The highest use is limited the quantity of according to each component, and the highest safe level of this patent preservative is 1.4%.

Claims (5)

1. a compound preservative, is characterized in that, solute and the Phenoxyethanol of mass ratio 1:1, consists of;
Wherein: described solute consists of the component of following mass percent: methyl p-hydroxybenzoate 1 ~ 40%, and ethyl-para-hydroxybenzoate 1 ~ 40%, propylparaben 1 ~ 20%, butyl p-hydroxybenzoate 1 ~ 15%, each component sum is 100%.
2. a kind of compound preservative according to claim 1, is characterized in that, solute and the Phenoxyethanol of mass ratio 1:1, consists of;
Wherein: described solute consists of the component of following mass percent: methyl p-hydroxybenzoate 10-35%, and ethyl-para-hydroxybenzoate 10 ~ 35%, propylparaben 5 ~ 20%, butyl p-hydroxybenzoate 5 ~ 15%, each component sum is 100%.
3. the purposes of compound preservative claimed in claim 1, is characterized in that, described compound preservative is as the purposes of skin-care product additive.
4. the purposes of compound preservative according to claim 3, is characterized in that, described compound preservative is as the purposes that contains the natural organic matter skin-care product additive.
5. the purposes of according to claim 3 or 4 described compound preservatives, is characterized in that, described compound preservative accounts for 0.5% of skin care item gross mass.
CN2013103611286A 2013-08-19 2013-08-19 Compound preservative and application thereof Pending CN103385241A (en)

Priority Applications (1)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105341622A (en) * 2015-10-19 2016-02-24 仲恺农业工程学院 Preservative composition and use thereof
JP2016210697A (en) * 2015-04-30 2016-12-15 上野製薬株式会社 Liquid antiseptic agent composition and manufacturing method therefor
CN106333214A (en) * 2016-08-30 2017-01-18 芜湖华海生物工程有限公司 Liquid preservative
CN106376822A (en) * 2016-08-30 2017-02-08 芜湖华海生物工程有限公司 Compounded liquid antiseptic for food
CN106376825A (en) * 2016-08-30 2017-02-08 芜湖华海生物工程有限公司 Powdery antiseptic
CN106387605A (en) * 2016-08-30 2017-02-15 芜湖华海生物工程有限公司 Special compound liquid preservative for foods
CN107467082A (en) * 2017-07-07 2017-12-15 太仓市荣德生物技术研究所 A kind of biological preservative having a safety feature

Citations (1)

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CN101370475A (en) * 2005-11-25 2009-02-18 “Wds”公司 Treating and preventing preparation used for oral nursing

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CN101370475A (en) * 2005-11-25 2009-02-18 “Wds”公司 Treating and preventing preparation used for oral nursing

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"化妆品配方", 《日用化学品科学》, vol. 30, no. 11, 25 November 2007 (2007-11-25), pages 46 - 48 *
吕长生: "尼泊金酯类防腐剂防腐效果的细菌学测定", 《日用化学工业》, no. 04, 20 August 1984 (1984-08-20), pages 33 - 38 *
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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016210697A (en) * 2015-04-30 2016-12-15 上野製薬株式会社 Liquid antiseptic agent composition and manufacturing method therefor
CN105341622A (en) * 2015-10-19 2016-02-24 仲恺农业工程学院 Preservative composition and use thereof
CN105341622B (en) * 2015-10-19 2019-07-12 仲恺农业工程学院 Antiseptic composition and application thereof
CN106333214A (en) * 2016-08-30 2017-01-18 芜湖华海生物工程有限公司 Liquid preservative
CN106376822A (en) * 2016-08-30 2017-02-08 芜湖华海生物工程有限公司 Compounded liquid antiseptic for food
CN106376825A (en) * 2016-08-30 2017-02-08 芜湖华海生物工程有限公司 Powdery antiseptic
CN106387605A (en) * 2016-08-30 2017-02-15 芜湖华海生物工程有限公司 Special compound liquid preservative for foods
CN107467082A (en) * 2017-07-07 2017-12-15 太仓市荣德生物技术研究所 A kind of biological preservative having a safety feature

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Application publication date: 20131113