CN103372144B - One treats neurasthenic Chinese medicine preparation and preparation method - Google Patents
One treats neurasthenic Chinese medicine preparation and preparation method Download PDFInfo
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Abstract
The present invention relates to one and treat neurasthenic Chinese medicine preparation and preparation method, this Chinese medicine preparation be by Pericarpium Citri Reticulatae, Ramulus Uncariae Cum Uncis, the Radix Rehmanniae, Periostracum Cicadae, Rhizoma Alismatis, Rhizoma Chuanxiong, Fructus Schisandrae Chinensis, Radix Polygalae, the Radix Aucklandiae, embryo nelumbinis, Radix Codonopsis, Rhizoma Polygonati Odorati, Fructus Lycii, rake leaf, Radix Glycyrrhizae Preparata, Rhizoma Gastrodiae, Cornu Cervi Degelatinatum, embryo nelumbinis totally ten eight taste Chinese drug preparations form.Medicine of the present invention all adopts herbal prescription, can make that heart kidney must be supported, the five internal organs fill Sheng, and QI and blood is smooth, has good therapeutical effect to symptoms such as insomnia and dreamful sleep, difficulty falling asleep, emotion agitation, dizziness and blurred vision, soreness of the waist and knees; Compared with prior art, the technique of this medicine is more reasonable, and clinical pharrnacokinetics experiment effect is remarkable, and bioavailability is high, and medicine stability is good, without any toxic and side effects, is a kind of Chinese medicine preparation for the treatment of neurasthenia safely and effectively.
Description
Art
The invention belongs to technical field of traditional Chinese medicine pharmacy, particularly relate to one and treat neurasthenic Chinese medicine preparation and preparation method.
Background technology
Neurasthenia is clinical common and disease that is that heal compared with refractory, along with the develop rapidly of society and the continuous quickening of people's rhythm of life, the life of the people, study, operating pressure are increasing, rest and sleep do not have rule, health is in subhealth state, sickness rate is caused to be the trend risen year by year, owing to more easily not forming obstinate asomnia for a long time.Neurasthenia is mainly manifested in the imbalance of brain higher nervous activity, is characterized in often feeling mental and being short of physical strength, and easily tired, work efficiency is low, but exists without organic disease.Can occur clinically being multiplely not suitable with symptom, as insomnia and dreamful sleep, difficulty falling asleep, emotion agitation, dizziness and blurred vision, soreness of the waist and knees, palpitation and short breath, premature ejaculation sexual impotence, menoxenia, can with minor depressive or anxiety.
Neurasthenia belongs in Chinese medicine " being insomnia " category.It is often can not obtain a kind of disease that ortho sleep is feature.The cause of disease has deficiency of both the heart and spleen more, hyperactivity of fire caused by deficiency of YIN, caused by timidness due to deficiency of the heart and disorder of the stomach.Control with tonic heart spleen with angry blood, or nourishing kidney yin, clearing heart fire, or QI invigorating is relieving convulsion, tranquilizing the mind, or stomach function regulating food stagnation removing, reducing phlegm and fever etc.Clinically, though neurasthenia has dividing of deficiency and excess, the most common with deficient syndrome.
Neurasthenia is normally with reinforce insufficiency and reduce excessiveness in Chinese medicine treatment, regulating YIN and YANG, and calming the nerves calm is principle.Being used for the treatment of clinically at present neurasthenicly has Cinnabaris to repose ball, ZAOREN ANSHEN YE etc.These medicines have certain curative effect to neurasthenia, but also there are some problems, and as drug effect is slow, Time of Administration is long, and curative effect is unstable etc.The neurasthenic medicine of western medical treatment has a lot, these medicines also have obvious effect to anxiety reduction, calmness, improving water flood etc., but can not cure, if much hypnotic sedative dose of long-term taking or excessive uses, also human body is easily formed to the dependency of medicine and generation drug resistance, also have certain side effect, long-term taking does harm rather than good the healthy of patient.
At present, in China adult, neurasthenic prevalence is 13.03 ‰, accounts for 58.7% of whole neurosis case, is the current modal neurosis of China.Neurastheniac owing to identifying oneself for a long time to be possessed by the demon of disease so that nervous, anxiety, agitation, do not have enough sleep, inappetence, immunity degradation, also can concurrent other diseases.Not only seriously affect study, work and future, also add burden to family, even affect the harmony of family.Therefore, though this sick life not jeopardizing patient of neurasthenia, do not affect the life-span, have impact on physical and mental health and the orthobiosis of people to a certain extent.
Summary of the invention
The object of the invention is the problem that treatment time is grown, curative effect lastingly, does not easily produce dependency, toxic and side effects is large existed for solving the neurasthenic medicine of existing treatment, one is provided to treat neurasthenic Chinese medicine preparation and preparation method, medicine of the present invention has rapid-action, cure rate is high, no dependence and the feature had no side effect.
Being implemented as follows of technical scheme of the present invention:
Chinese medicine preparation of the present invention is made up of following raw materials by weight portion:
Pericarpium Citri Reticulatae 80 ~ 200 parts of Ramulus Uncariae Cum Uncis 80 ~ 200 parts of Radix Rehmanniae 80 ~ 200 parts of Periostracum Cicadaes 60 ~ 150 parts
Rhizoma Alismatis 60 ~ 150 parts of Rhizoma Chuanxiongs 80 ~ 200 parts of Fructus Schisandrae Chinensis 80 ~ 200 parts of Radix Polygalaes 50 ~ 120 parts
The Radix Aucklandiae 50 ~ 120 parts of embryo nelumbinises 60 ~ 150 parts of Radix Codonopsis 60 ~ 150 portions of Rhizoma Polygonati Odorati 60 ~ 150 parts
50 ~ 120 parts, Fructus Lycii 50 ~ 120 parts of rake leaves 80 ~ 200 parts of Radix Glycyrrhizae Preparatas 60 ~ 150 parts of Rhizoma Gastrodiaes
Cornu Cervi Degelatinatum 30 ~ 100 parts of embryo nelumbinises 30 ~ 100 parts
Described Chinese medicine preparation is made up of following raw materials by weight portion:
Pericarpium Citri Reticulatae 90 ~ 180 parts of Ramulus Uncariae Cum Uncis 90 ~ 180 parts of Radix Rehmanniae 90 ~ 180 parts of Periostracum Cicadaes 70 ~ 140 parts
Rhizoma Alismatis 70 ~ 140 parts of Rhizoma Chuanxiongs 90 ~ 180 parts of Fructus Schisandrae Chinensis 90 ~ 180 parts of Radix Polygalaes 60 ~ 110 parts
The Radix Aucklandiae 60 ~ 110 parts of embryo nelumbinises 70 ~ 140 parts of Radix Codonopsis 70 ~ 140 portions of Rhizoma Polygonati Odorati 70 ~ 140 parts
60 ~ 110 parts, Fructus Lycii 60 ~ 110 parts of rake leaves 90 ~ 180 parts of Radix Glycyrrhizae Preparatas 70 ~ 140 parts of Rhizoma Gastrodiaes
Cornu Cervi Degelatinatum 40 ~ 90 parts of embryo nelumbinises 40 ~ 90 parts
Described Chinese medicine preparation is made up of following raw materials by weight portion:
Pericarpium Citri Reticulatae 140 parts of Ramulus Uncariae Cum Uncis 140 parts of Radix Rehmanniae 140 parts of Periostracum Cicadaes 100 parts
Rhizoma Alismatis 100 parts of Rhizoma Chuanxiongs 140 parts of Fructus Schisandrae Chinensis 140 parts of Radix Polygalaes 80 parts
The Radix Aucklandiae 80 parts of embryo nelumbinises 100 parts of Radix Codonopsis 100 portions of Rhizoma Polygonati Odorati 100 parts
80 parts, Fructus Lycii 80 parts of rake leaves 140 parts of Radix Glycyrrhizae Preparatas 100 parts of Rhizoma Gastrodiaes
Cornu Cervi Degelatinatum 60 parts of embryo nelumbinises 60 parts
Described Chinese medicine preparation adopts following method to obtain:
(1) Pericarpium Citri Reticulatae, Ramulus Uncariae Cum Uncis, the Radix Rehmanniae, Periostracum Cicadae, Rhizoma Alismatis add 50% alcohol dipping twice, first time floods 24 hours, and second time dipping 12 hours, considered, filtrate is decompression recycling ethanol under the condition of-0.07 ~-0.08mpa, and when being concentrated into 80 DEG C, relative density is the thick paste of 1.31 ~ 1.32.
(2) Rhizoma Chuanxiong, Fructus Schisandrae Chinensis, Radix Polygalae, the Radix Aucklandiae, embryo nelumbinis, Radix Codonopsis, Rhizoma Polygonati Odorati, Fructus Lycii, rake leaf, Radix Glycyrrhizae Preparata, Rhizoma Gastrodiae, Cornu Cervi Degelatinatum, embryo nelumbinis add 8 times of soak by water twice, 2 hours first times, second time 1 hour, considered, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08 ~ 1.14, adds 3.5 times amount ethanol, stir evenly, be heated to 80 DEG C, leave standstill 24 hours, considered, filtrate is decompression recycling ethanol under the condition of-0.07 ~-0.08mpa, is condensed into thick paste.
(3) by step (1) gained thick paste and the mixing of step (2) gained thick paste, be ground into fine powder, stir, make the watered pill.
The application in the disease medicament of preparation treatment neurasthenia, insomnia forgetfulness, dizzy nervous, irritated dreaminess of described Chinese medicine preparation and preparation method.
The present invention has following beneficial effect:
Medicine of the present invention all adopts herbal prescription, has the blood that nourishes heart significantly, tranquilizing mind, falls fidgets due to deficiency, effect that resolving depression is had one's ideas straightened out; , the symptom such as hypomnesis, dizzy cardiopalmus, soreness of the waist and knees forgetful to neurasthenia, insomnia and dreamful sleep, anxiety has good therapeutical effect; Compared with prior art, the technique of this medicine is more reasonable, and clinical pharrnacokinetics experiment effect is remarkable, and bioavailability is high, and medicine stability is good, without any toxic and side effects, is a kind of Chinese medicine preparation for the treatment of neurasthenia safely and effectively.
Model case:
Case one: Song, female, 18 years old, school high school student, owing to learning anxiety, overtime work is stayed up late and is reviewed lessons every night, the book of going home to read again two hours after lower self-study at night is fallen asleep again, due to brain overwork, daytime dizziness, hypomnesis, attention can not concentrate, evening, insomnia and dreamful sleep, was not easy to fall asleep.Diagnosis and treatment through doctor show that the cause of disease is neurasthenia, eat multiple nutriment, and drinking invigorating brain and relieving mental uneasiness oral liquid does not have effect yet.Just can fall asleep very soon after taking the neurasthenic Chinese medicine preparation two weeks of this treatment, day person, memory and attention significantly improve, and recover ortho sleep function completely after one month, health returns to one's perfect health.
Case two: Zhu, man, 42 years old, married, Company portion is responsible for, because insomnia and dreamful sleep, anxiety agitation, dizzy cardiopalmus, soreness of the waist and knees come institute and go to a doctor.Patient supports because the many fatigues of thing, operating pressure cause greatly deficiency of both QI and blood, brain to lose, and after taking this treatment neurasthenic each and every one week of Chinese medicine preparation two, all recover normal.
Case three: Liu, female, 27 years old, office staff, the work hours were often felt that asthenia is drowsy, have one's head in the clouds, and cause work efficiency low, and in company, normal losing control of because of minor matter is disputed with people, but regrets again afterwards and apologize.At nightfall, toss about, have difficulty in going to sleep, need two or three hours ability to fall asleep, easily wake up with a start after sleeping.Take the neurasthenic Chinese medicine preparation of this treatment after one month, all recover normal.
Detailed description of the invention
The present invention is done supplementary further below in conjunction with specific embodiment, but do not limit the present invention in any way.
Embodiment 1
The present embodiment is made up of following raw materials by weight portion:
Pericarpium Citri Reticulatae 80 ~ 200 parts of Ramulus Uncariae Cum Uncis 80 ~ 200 parts of Radix Rehmanniae 80 ~ 200 parts of Periostracum Cicadaes 60 ~ 150 parts
Rhizoma Alismatis 60 ~ 150 parts of Rhizoma Chuanxiongs 80 ~ 200 parts of Fructus Schisandrae Chinensis 80 ~ 200 parts of Radix Polygalaes 50 ~ 120 parts
The Radix Aucklandiae 50 ~ 120 parts of embryo nelumbinises 60 ~ 150 parts of Radix Codonopsis 60 ~ 150 portions of Rhizoma Polygonati Odorati 60 ~ 150 parts
50 ~ 120 parts, Fructus Lycii 50 ~ 120 parts of rake leaves 80 ~ 200 parts of Radix Glycyrrhizae Preparatas 60 ~ 150 parts of Rhizoma Gastrodiaes
Cornu Cervi Degelatinatum 30 ~ 100 parts of embryo nelumbinises 30 ~ 100 parts
The manufacture method of the present embodiment is:
(1) Pericarpium Citri Reticulatae, Ramulus Uncariae Cum Uncis, the Radix Rehmanniae, Periostracum Cicadae, Rhizoma Alismatis add 50% alcohol dipping twice, first time floods 24 hours, and second time dipping 12 hours, considered, filtrate is decompression recycling ethanol under the condition of-0.07 ~-0.08mpa, and when being concentrated into 80 DEG C, relative density is the thick paste of 1.31 ~ 1.32.
(2) Rhizoma Chuanxiong, Fructus Schisandrae Chinensis, Radix Polygalae, the Radix Aucklandiae, embryo nelumbinis, Radix Codonopsis, Rhizoma Polygonati Odorati, Fructus Lycii, rake leaf, Radix Glycyrrhizae Preparata, Rhizoma Gastrodiae, Cornu Cervi Degelatinatum, embryo nelumbinis add 8 times of soak by water twice, 2 hours first times, second time 1 hour, considered, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08 ~ 1.14, adds 3.5 times amount ethanol, stir evenly, be heated to 80 DEG C, leave standstill 24 hours, considered, filtrate is decompression recycling ethanol under the condition of-0.07 ~-0.08mpa, is condensed into thick paste.
(3) by step (1) gained thick paste and the mixing of step (2) gained thick paste, be ground into fine powder, stir, make the watered pill.
Embodiment 2
The present embodiment is made up of following raw materials by weight portion:
Pericarpium Citri Reticulatae 90 ~ 180 parts of Ramulus Uncariae Cum Uncis 90 ~ 180 parts of Radix Rehmanniae 90 ~ 180 parts of Periostracum Cicadaes 70 ~ 140 parts
Rhizoma Alismatis 70 ~ 140 parts of Rhizoma Chuanxiongs 90 ~ 180 parts of Fructus Schisandrae Chinensis 90 ~ 180 parts of Radix Polygalaes 60 ~ 110 parts
The Radix Aucklandiae 60 ~ 110 parts of embryo nelumbinises 70 ~ 140 parts of Radix Codonopsis 70 ~ 140 portions of Rhizoma Polygonati Odorati 70 ~ 140 parts
60 ~ 110 parts, Fructus Lycii 60 ~ 110 parts of rake leaves 90 ~ 180 parts of Radix Glycyrrhizae Preparatas 70 ~ 140 parts of Rhizoma Gastrodiaes
Cornu Cervi Degelatinatum 40 ~ 90 parts of embryo nelumbinises 40 ~ 90 parts
The manufacture method of the present embodiment is identical with embodiment 1.
Embodiment 3
Pericarpium Citri Reticulatae 140 parts of Ramulus Uncariae Cum Uncis 140 parts of Radix Rehmanniae 140 parts of Periostracum Cicadaes 100 parts
Rhizoma Alismatis 100 parts of Rhizoma Chuanxiongs 140 parts of Fructus Schisandrae Chinensis 140 parts of Radix Polygalaes 80 parts
The Radix Aucklandiae 80 parts of embryo nelumbinises 100 parts of Radix Codonopsis 100 portions of Rhizoma Polygonati Odorati 100 parts
80 parts, Fructus Lycii 80 parts of rake leaves 140 parts of Radix Glycyrrhizae Preparatas 100 parts of Rhizoma Gastrodiaes
Cornu Cervi Degelatinatum 60 parts of embryo nelumbinises 60 parts
The manufacture method of the present embodiment is identical with embodiment 1.
Claims (4)
1. treat a neurasthenic Chinese medicine preparation, it is characterized in that it is made up of following raw materials by weight portion:
2. one according to claim 1 treats neurasthenic Chinese medicine preparation, it is characterized in that it is made up of following raw materials by weight portion:
3. one according to claim 1 and 2 treats neurasthenic Chinese medicine preparation, it is characterized in that it is made up of following raw materials by weight portion:
4. according to any one of claims 1 to 3, one treats neurasthenic Chinese medicine preparation, it is characterized in that, the application of described Chinese medicine preparation in the disease medicament of preparation treatment neurasthenia, insomnia forgetfulness, dizzy nervous, irritated dreaminess.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1772263A (en) * | 2005-10-27 | 2006-05-17 | 刘清华 | Neurosism treating medicine |
| CN1872204A (en) * | 2006-04-24 | 2006-12-06 | 江西天施康中药股份有限公司 | Medication composition for treating neurasthenia, preparation technique, and method for testing quality |
| CN101966290A (en) * | 2010-09-29 | 2011-02-09 | 申东升 | Medicament for treating neurasthenia and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1772263A (en) * | 2005-10-27 | 2006-05-17 | 刘清华 | Neurosism treating medicine |
| CN1872204A (en) * | 2006-04-24 | 2006-12-06 | 江西天施康中药股份有限公司 | Medication composition for treating neurasthenia, preparation technique, and method for testing quality |
| CN101966290A (en) * | 2010-09-29 | 2011-02-09 | 申东升 | Medicament for treating neurasthenia and preparation method thereof |
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Inventor after: Fu Shengguo Inventor after: Geng Xueli Inventor after: Wang Zhaowei Inventor before: Song Yanjie Inventor before: Gao Shuxia Inventor before: Liu Bin |
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Effective date of registration: 20170703 Address after: 271600 Feicheng Hospital of Traditional Chinese Medicine, 024 Changshan street, Shandong, Tai'an, Feicheng Patentee after: Fu Shengguo Address before: 262500 Shandong province Qingzhou City Linglong Mountain Road No. 4138 Weifang Yidu Central Hospital Patentee before: Song Yanjie |
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