CN103341113A

CN103341113A - Chinese medicine composition for treating chronic gastritis

Info

Publication number: CN103341113A
Application number: CN2013102611683A
Authority: CN
Inventors: 柳晖
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-06-27
Filing date: 2013-06-27
Publication date: 2013-10-09
Anticipated expiration: 2033-06-27
Also published as: CN103341113B

Abstract

The invention relates to a Chinese medicine composition for treating chronic gastritis. The Chinese medicine composition comprises the following Chinese medicine raw materials in parts by weight: 10-40 parts of codonopsis pilosula, 10-30 parts of poria cocos, 10-40 parts of rhizoma atractylodis macrocephalae, 5-15 parts of fructus amomi, 5-15 parts of rhizoma cyperi, 5-15 parts of rheum officinale, 10-30 parts of cuttlebone, 5-15 parts of the root of three-nerved spicebush, 10-20 parts of fructus aurantii, 10-20 parts of fingered citron, 20-40 parts of lily, 5-15 parts of platycodon grandiflorum, 10-30 parts of dandelion, 5-15 parts of magnolia obavata, 10-40 parts of Chinese yam, 10-30 parts of rhizoma corydalis, 5-15 parts of pinellia ternate, 5-15 parts of dried tangerine or orange peel, 5-10 parts of liquorice and 5-15 parts of elecampane. The Chinese medicine composition has the effects of relieving the liver, regulating the qi, strengthening the spleen, tonifying the lung, reinforcing the stomach, tonifying the kidney, relieving sluggish and eliminating swelling, and is remarkable in effect on treating chronic gastritis and reliable in function, and the ingredients of the Chinese medicine composition is wide in source, simple and convenient to prepare and free of toxic and side effects.

Description

A kind of Chinese medicine composition for the treatment of chronic gastritis

Technical field

The present invention relates to a kind of medicinal preparation of not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of chronic gastritis.

Background technology

Chronic gastritis is the gastric mucosa inflammation.Modal is chronic superficial gastritis and chronic atrophic gastritis.Its main clinical manifestation is loss of appetite, epigastric discomfort and dull pain, belch, pantothenic acid, feel sick, vomiting etc.The morbidity of chronic gastritis may be relevant with following factor: the anti-stream of the sequel of acute gastritis, irritable food and medicine, duodenal juice, immune factor, infective agent etc.At present, treat chronic gastritis clinically and use antibiotics more, have the deficiency of curing the symptoms, not the disease.

Chronic gastritis belongs to sick categories such as Chinese medicine " gastric abscess ", " feeling of fullness ", " acid regurgitation ", " noisy ", " indigestion and loss of appetite ".

The traditional Chinese medical science thinks that chronic gastritis is many because feelings will is unsuccessful for a long time, eating and drinking without temperance, and work and rest is not normal, causes depression of liver-QI, dysfunction of the spleen in transportation, gastral cavilty is become estranged, and with the passing of time middle gas loses empty, thereby causes all symptoms.

According to theory of Chinese medical science, at the pathogeny of chronic gastritis, be the rule for the treatment of with liver-smoothing, qi-regulating, invigorating spleen and reinforcing stomach, dyspepsia and intestinal stasis relieving, carry out dialectical composition of prescription, to reach the purpose for the treatment of both the principal and secondary aspects of a disease.

Summary of the invention

Have the deficiency of curing the symptoms, not the disease in order to overcome the treatment of antibiotics in prior art chronic gastritis, the invention provides a kind ofly prepare conveniently, the medicine source is wide, cost is low, the Chinese medicine composition of evident in efficacy, reliable effect, the treatment chronic gastritis that has no side effect.

The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of chronic gastritis is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Radix Codonopsis 10-40 part, Poria 10-30 part, Rhizoma Atractylodis Macrocephalae 10-40 part, Fructus Amomi 5-15 part, Rhizoma Cyperi 5-15 part, Radix Et Rhizoma Rhei 5-15 part, Endoconcha Sepiae 10-30 part, Radix Linderae 5-15 part, Fructus Aurantii 10-20 part, Fructus Citri Sarcodactylis 10-20 part, Bulbus Lilii 20-40 part, Radix Platycodonis 5-15 part, Herba Taraxaci 10-30 part, Cortex Magnoliae Officinalis 5-15 part, Rhizoma Dioscoreae 10-40 part, Rhizoma Corydalis 10-30 part, Rhizoma Pinelliae 5-15 part, Pericarpium Citri Reticulatae 5-15 part, Radix Glycyrrhizae 5-10 part and Radix Aucklandiae 5-15 part.

The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of chronic gastritis is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 10 parts of 30 parts of Radix Codonopsis, 20 parts in Poria, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Fructus Amomis, 10 parts of Rhizoma Cyperis, 10 parts of Radix Et Rhizoma Rhei, 20 parts of Endoconcha Sepiaes, 10 parts of the Radixs Linderae, 15 parts of Fructus Aurantiis, 15 parts of Fructus Citri Sarcodactylis, 30 parts of Bulbus Liliies, 10 parts of Radix Platycodoniss, 20 parts of Herba Taraxacis, 10 parts of Cortex Magnoliae Officinalis, 30 parts of Rhizoma Dioscoreaes, 20 parts of Rhizoma Corydalis, 10 parts of the Rhizoma Pinelliaes, 10 parts of Pericarpium Citri Reticulataes, 6 parts in Radix Glycyrrhizae and the Radix Aucklandiae.

Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In the Chinese medicine composition of the present invention: Radix Codonopsis has the effect of invigorating the spleen and replenishing QI, spleen invigorating lung benefiting; Poria has the effect of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming; The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, the antiabortive effect of hidroschesis; Fructus Amomi has the removing dampness appetizing, and is warming spleen and stopping diarrha, the antiabortive effect of regulating the flow of vital energy; Rhizoma Cyperi has the effect of the resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving; Rhizoma Cyperi has the effect of liver-smoothing, qi-regulating, resolving depression pain relieving; Radix Et Rhizoma Rhei has the effect of pathogenic fire purging removing food stagnancy, heat-clearing and toxic substances removing, cooling blood for hemostasis, blood stasis dispelling cough-relieving; Endoconcha Sepiae has the effect that astringing to arrest bleeding, treating spontaneous emission and leukorrhagia, relieving gastric hyperacidity to alleviate stomachache, removing dampness are held back skin ulcer; The Radix Linderae has the effect of promoting the circulation of QI to relieve pain, warming kidney for dispelling cold; Fructus Aurantii has the effect of regulating the flow of QI to ease the stomach, the stagnant relieving distension of row; Fructus Citri Sarcodactylis has the effect of liver-smoothing, qi-regulating and stomach and alleviating pain; Bulbus Lilii has the effect of nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization, nourishing essence-blood; Radix Platycodonis has lung qi dispersing and eliminates the phlegm, fosters the spirit of nobility and enrich blood, sharp the five internal organs, mend the effect of five kinds of over strain; Herba Taraxaci has the effect of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; Cortex Magnoliae Officinalis has the circulation of qi promoting removing food stagnancy, and dampness is except expiring the effect of lowering the adverse QI to relieve asthma; Rhizoma Dioscoreae has strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, the benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, grow that will is calmed the nerves, effect of prolonging life; Rhizoma Corydalis has the effect of promoting blood circulation to remove blood stasis, promoting the circulation of QI pain relieving; The Rhizoma Pinelliae has drying dampness to eliminate phlegm, the effect of stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass; Pericarpium Citri Reticulatae has the effect of diuretic, drying dampness to eliminate phlegm in regulating qi-flowing for strengthening spleen, the accent; The Radix Aucklandiae has the effect of intestinal stasis relieving in promoting the circulation of QI to relieve pain, the accent; Radix Glycyrrhizae has the effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.Drug component in the present composition is through dialectical compatibility, complements each other using, and has synergism, plays the stagnate effect of relieving distension of liver-smoothing, qi-regulating, spleen invigorating lung benefiting, stomach reinforcing the kidney invigorating, row altogether, chronic gastritis reached the purpose for the treatment of both the principal and secondary aspects of a disease.

The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, the medicine source is wide, cost is low.It follows the prescription principle of medication of the traditional Chinese medical science, and various component drug adopt the usefulness that is decocted in water for oral dose.Through the clinical practice checking, it is evident in efficacy, reliable effect, and the property of medicine is gentle, toxic and side effects do not occur, total effective rate 90%, cure rate reaches 60%.

The specific embodiment

The present invention will be further described below in conjunction with embodiment.

Embodiment 1

A kind of Chinese medicine composition for the treatment of chronic gastritis, its raw material of Chinese medicine and weight proportion are: Radix Codonopsis 30g, Poria 20g, Rhizoma Atractylodis Macrocephalae 30g, Fructus Amomi 10g, Rhizoma Cyperi 10g, Radix Et Rhizoma Rhei 10g, Endoconcha Sepiae 20g, Radix Linderae 10g, Fructus Aurantii 15g, Fructus Citri Sarcodactylis 15g, Bulbus Lilii 30g, Radix Platycodonis 10g, Herba Taraxaci 20g, Cortex Magnoliae Officinalis 10g, Rhizoma Dioscoreae 30g, Rhizoma Corydalis 20g, Rhizoma Pinelliae 10g, Pericarpium Citri Reticulatae 10g, Radix Glycyrrhizae 6g and Radix Aucklandiae 10g.

Embodiment 2

A kind of Chinese medicine composition for the treatment of chronic gastritis, its raw material of Chinese medicine and weight proportion are: Radix Codonopsis 10g, Poria 30g, Rhizoma Atractylodis Macrocephalae 10g, Fructus Amomi 15g, Rhizoma Cyperi 5g, Radix Et Rhizoma Rhei 15g, Endoconcha Sepiae 10g, Radix Linderae 15g, Fructus Aurantii 10g, Fructus Citri Sarcodactylis 10g, Bulbus Lilii 40g, Radix Platycodonis 5g, Herba Taraxaci 30g, Cortex Magnoliae Officinalis 5g, Rhizoma Dioscoreae 40g, Rhizoma Corydalis 10g, Rhizoma Pinelliae 15g, Pericarpium Citri Reticulatae 5g, Radix Glycyrrhizae 9g and Radix Aucklandiae 5g.

Embodiment 3

A kind of Chinese medicine composition for the treatment of chronic gastritis, its raw material of Chinese medicine and weight proportion are: Radix Codonopsis 40g, Poria 10g, Rhizoma Atractylodis Macrocephalae 40g, Fructus Amomi 5g, Rhizoma Cyperi 15g, Radix Et Rhizoma Rhei 5g, Endoconcha Sepiae 30g, Radix Linderae 5g, Fructus Aurantii 20g, Fructus Citri Sarcodactylis 20g, Bulbus Lilii 20g, Radix Platycodonis 15g, Herba Taraxaci 10g, Cortex Magnoliae Officinalis 15g, Rhizoma Dioscoreae 20g, Rhizoma Corydalis 30g, Rhizoma Pinelliae 5g, Pericarpium Citri Reticulatae 15g, Radix Glycyrrhizae 5g and Radix Aucklandiae 15g.

Embodiment 4

A kind of Chinese medicine composition for the treatment of chronic gastritis, its raw material of Chinese medicine and weight proportion are: Radix Codonopsis 25g, Poria 25g, Rhizoma Atractylodis Macrocephalae 25g, Fructus Amomi 13g, Rhizoma Cyperi 8g, Radix Et Rhizoma Rhei 13g, Endoconcha Sepiae 15g, Radix Linderae 13g, Fructus Aurantii 12g, Fructus Citri Sarcodactylis 12g, Bulbus Lilii 35g, Radix Platycodonis 8g, Herba Taraxaci 25g, Cortex Magnoliae Officinalis 9g, Rhizoma Dioscoreae 35g, Rhizoma Corydalis 15g, Rhizoma Pinelliae 13g, Pericarpium Citri Reticulatae 7g, Radix Glycyrrhizae 10g and Radix Aucklandiae 8g.

Embodiment 5

A kind of Chinese medicine composition for the treatment of chronic gastritis, its raw material of Chinese medicine and weight proportion are: Radix Codonopsis 35g, Poria 15g, Rhizoma Atractylodis Macrocephalae 35g, Fructus Amomi 8g, Rhizoma Cyperi 13g, Radix Et Rhizoma Rhei 8g, Endoconcha Sepiae 25g, Radix Linderae 8g, Fructus Aurantii 18g, Fructus Citri Sarcodactylis 18g, Bulbus Lilii 25g, Radix Platycodonis 13g, Herba Taraxaci 15g, Cortex Magnoliae Officinalis 13g, Rhizoma Dioscoreae 25g, Rhizoma Corydalis 25g, Rhizoma Pinelliae 8g, Pericarpium Citri Reticulatae 13g, Radix Glycyrrhizae 8g and Radix Aucklandiae 13g.

Chinese medicine composition in embodiment of the invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soaked 15～20 minutes, add water again and do not have about 6 centimetres of powder, carry out the decoction first time, at a simmer the preceding intense fire that adopts decocts, and slow fire boiling 20～30 minutes are used in the back of boiling; Second decocts, and adds water and does not have about 6 centimetres of powder, decocts 15～20 minutes after water boils.Twice decoction extracting juice that removes slag merges.

The present invention does clinical efficacy and is summarized as follows with the given a kind of Chinese medicine composition for the treatment of chronic gastritis of embodiment 1:

One, general data: Chinese medicine composition of the present invention is applied to clinical observation case 50 examples, male 25 examples wherein, women 25 examples, 20～70 years old age.The shortest person of the course of disease 4 months, elder reaches 2 years, average 0.5 year.

Two, diagnostic criteria:

(1) superficial gastritis

1, asymptomatic or upper abdominal pain, glutted, belch, decreased food intake etc. are arranged, idol has upper gastrointestinal hemorrhage;

2, x-ray barium meal examination lacks positive sign;

3, gastric analysis: gastric acid is normal or high slightly;

4. endoscopy is seen mucosa (reddish tint is main) red and white, and edema has thick, sticky mucus to adhere to, and can have rotten to the corn and hemorrhage; The mucosa biopsy is the shallow-layer inflammatory cell infiltration, and body of gland is normal;

(2) atrophic gastritis typing standard is as follows:

1, body of stomach gastritis (A type): pathological changes is at body of stomach, diffusivity; Gastric acid lacks as or obviously lowers; Serum gastrin raises; Parietal cell antibodies (PCA) etc. are most positive; IFA can be positive, can merge pernicious anemia;

2, gastric antrum gastritis (Type B): pathological changes can be involved body, kitchen range mainly at gastric antrum; Gastric acid is normal or lower slightly; Serum gastrin is normal; BCA, PCA may be positive, but canceration (＜4%).Microscopy: can make a definite diagnosis, pathological changes can be confined to body of stomach or gastric antrum portion, but also disperse; Mucosa is greyish white or red and white (Bai Xiangwei master), and pleat attenuates, the mucosa attenuation, and blood vessel is seen thoroughly under the mucosa; Sometimes gland nest hypertrophy, local mucous membrane thickening are graininess and change (cross and form).The holostrome cell infiltration is seen in the mucosa biopsy, and big of body of gland disappears or complete obiteration (gastratrophia), and generation, severe patient had atypical hyperplasia with intestinal gland metaplasia or pylorus glandular metaplasia.

Three, usage and dosage: during clinical practice, the component in the compositions, consumption are taken the circumstances into consideration increase and decrease according to patient's body weight, age and symptom.One day potion, the about 300ml of twice extracting juice of decocting, divide early, late twice half an hour ante cibum warm taking.Period in a medicine avoids eating anything raw or cold, pungent thing.

Four, criterion of therapeutical effect:

(1), cure: clinical cardinal symptom and sign disappear, and chronic inflammatory disease is pass on well slightly;

(2), take a turn for the better: clinical cardinal symptom disappears, and minor symptom disappears substantially, and chronic inflammatory disease takes a turn for the better;

(3), invalid; The cardinal symptom no change does not worsen yet.

Five, therapeutic effect: in this clinical observation case, took medicine 5-30 days, cure 30 examples, 15 examples that take a turn for the better, 5 examples do not heal.Toxic and side effects does not take place during the treatment.

Six, model case:

Case 1:

Liu, the woman, 42 years old, it is surplus that readme suffers from chronic atrophic gastritis 2 years, abdominal distention, the uncomfortable companion of epigastrium dull pain belch return acid, heartburn sense recently, stool once a day, the self-induction stool is not smooth.Take the medicament of Chinese medicine composition preparation of the present invention after 7 days, abdominal distention, stomachache alleviate slightly behind the conscious medicine, heartburn, acid regurgitation do not occur; After continuing to take 5 days, abdominal distention, stomachache not obvious; Diet increases, and is comfortable in the stomach of food back, no singultus, heartburn, acid regurgitation symptom; Continue to strengthen and take 5 days, cure.

Case 2:

Zhang, the man, 50 years old, normal upper abdomen and the upper abdomen paroxysmal pain that takes over down, pain increases the weight of when unhappy, and diet is poor, with feeling sick, detests oil, and the half a year of suffering from diarrhoea is surplus, looks into through gastroscope to be diagnosed as: chronic gastritis.Take the medicament 5 days of Chinese medicine composition of the present invention preparation, food is received and is become good, and paroxysmal pain, diarrhoea number of times reduce; Continuous clothes 7 days, paroxysmal pain, diarrhoea all disappear, and every day, defecation was 1 time, and feces is normal; Continue to strengthen and take 3 days, cure.

Claims

1. Chinese medicine composition for the treatment of chronic gastritis, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Radix Codonopsis 10-40 part, Poria 10-30 part, Rhizoma Atractylodis Macrocephalae 10-40 part, Fructus Amomi 5-15 part, Rhizoma Cyperi 5-15 part, Radix Et Rhizoma Rhei 5-15 part, Endoconcha Sepiae 10-30 part, Radix Linderae 5-15 part, Fructus Aurantii 10-20 part, Fructus Citri Sarcodactylis 10-20 part, Bulbus Lilii 20-40 part, Radix Platycodonis 5-15 part, Herba Taraxaci 10-30 part, Cortex Magnoliae Officinalis 5-15 part, Rhizoma Dioscoreae 10-40 part, Rhizoma Corydalis 10-30 part, Rhizoma Pinelliae 5-15 part, Pericarpium Citri Reticulatae 5-15 part, Radix Glycyrrhizae 5-10 part and Radix Aucklandiae 5-15 part.

2. a kind of Chinese medicine composition for the treatment of chronic gastritis according to claim 1, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 10 parts of 30 parts of Radix Codonopsis, 20 parts in Poria, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Fructus Amomis, 10 parts of Rhizoma Cyperis, 10 parts of Radix Et Rhizoma Rhei, 20 parts of Endoconcha Sepiaes, 10 parts of the Radixs Linderae, 15 parts of Fructus Aurantiis, 15 parts of Fructus Citri Sarcodactylis, 30 parts of Bulbus Liliies, 10 parts of Radix Platycodoniss, 20 parts of Herba Taraxacis, 10 parts of Cortex Magnoliae Officinalis, 30 parts of Rhizoma Dioscoreaes, 20 parts of Rhizoma Corydalis, 10 parts of the Rhizoma Pinelliaes, 10 parts of Pericarpium Citri Reticulataes, 6 parts in Radix Glycyrrhizae and the Radix Aucklandiae.