CN103339103B - [((1r,2s,5r)-2-异丙基-5-甲基-环己烷羰基)-氨基]乙酸异丙酯和相关化合物及它们在治疗中的应用 - Google Patents
[((1r,2s,5r)-2-异丙基-5-甲基-环己烷羰基)-氨基]乙酸异丙酯和相关化合物及它们在治疗中的应用 Download PDFInfo
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- CN103339103B CN103339103B CN201180066635.6A CN201180066635A CN103339103B CN 103339103 B CN103339103 B CN 103339103B CN 201180066635 A CN201180066635 A CN 201180066635A CN 103339103 B CN103339103 B CN 103339103B
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
Claims (42)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/928,184 US20110082204A1 (en) | 2005-03-29 | 2010-12-06 | N-alkylcarbonyl-amino acid ester and N-alkylcarbonyl-amino lactone compounds and their use |
US12/928,184 | 2010-12-06 | ||
PCT/GB2011/000520 WO2012076831A1 (en) | 2010-12-06 | 2011-04-04 | [((1r,2s,5r)-2-isopropyl-5-methyl-cyclohexanecarbonyl)-amino]-acetic acid isopropyl ester and related compounds and their use in therapy |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103339103A CN103339103A (zh) | 2013-10-02 |
CN103339103B true CN103339103B (zh) | 2015-06-17 |
Family
ID=44168849
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201180066635.6A Active CN103339103B (zh) | 2010-12-06 | 2011-04-04 | [((1r,2s,5r)-2-异丙基-5-甲基-环己烷羰基)-氨基]乙酸异丙酯和相关化合物及它们在治疗中的应用 |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP2649046B1 (zh) |
JP (1) | JP5702864B2 (zh) |
KR (1) | KR101920050B1 (zh) |
CN (1) | CN103339103B (zh) |
AU (1) | AU2011340295B2 (zh) |
CA (1) | CA2819466C (zh) |
RU (1) | RU2598644C2 (zh) |
SG (1) | SG190991A1 (zh) |
WO (1) | WO2012076831A1 (zh) |
ZA (1) | ZA201304896B (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20150272161A1 (en) * | 2011-12-21 | 2015-10-01 | Wm. Wrigley Jr. Company | Chewing gum products containing (r)-2-[((1r,2s,5r)-2-isopropyl-5-methylclohexanecarbonyl)-amino]-acetic acid isopropyl ester |
GB201908219D0 (en) | 2019-06-10 | 2019-07-24 | Axalbion Sa | Therapeutic use of a compound |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4178459A (en) * | 1971-02-04 | 1979-12-11 | Wilkinson Sword Limited | N-Substituted paramenthane carboxamides |
EP1656144B2 (en) * | 2003-07-02 | 2017-12-20 | Genentech, Inc. | Trp-p8 active compounds and therapeutic treatment methods |
US7189760B2 (en) * | 2004-04-02 | 2007-03-13 | Millennium Specialty Chemicals | Physiological cooling compositions containing highly purified ethyl ester of N-[[5-methyl-2-(1-methylethyl) cyclohexyl] carbonyl]glycine |
US7482378B2 (en) * | 2004-05-28 | 2009-01-27 | Millenium Specialty Chemicals, Inc. | Physiological cooling compositions |
RU2417218C2 (ru) * | 2005-03-29 | 2011-04-27 | Эдвард Так ВЕЙ | Эфиры n-алкилкарбониламинокислот и n-алкилкарбониламинолактоны и их применение |
EP1871738B1 (en) * | 2005-03-29 | 2009-07-15 | Edward T. Wei | N-alkylcarbonyl-amino acid ester and n-alkylcarbonyl-amino lactone compounds and their use |
-
2011
- 2011-04-04 SG SG2013043047A patent/SG190991A1/en unknown
- 2011-04-04 RU RU2013130166/04A patent/RU2598644C2/ru active
- 2011-04-04 CA CA2819466A patent/CA2819466C/en active Active
- 2011-04-04 KR KR1020137017649A patent/KR101920050B1/ko active IP Right Grant
- 2011-04-04 EP EP11715726.3A patent/EP2649046B1/en active Active
- 2011-04-04 JP JP2013542596A patent/JP5702864B2/ja active Active
- 2011-04-04 WO PCT/GB2011/000520 patent/WO2012076831A1/en active Application Filing
- 2011-04-04 CN CN201180066635.6A patent/CN103339103B/zh active Active
- 2011-04-04 AU AU2011340295A patent/AU2011340295B2/en active Active
-
2013
- 2013-07-01 ZA ZA2013/04896A patent/ZA201304896B/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN103339103A (zh) | 2013-10-02 |
CA2819466C (en) | 2019-11-26 |
SG190991A1 (en) | 2013-07-31 |
EP2649046A1 (en) | 2013-10-16 |
JP2014503513A (ja) | 2014-02-13 |
EP2649046B1 (en) | 2016-12-07 |
AU2011340295B2 (en) | 2016-11-03 |
RU2013130166A (ru) | 2015-01-20 |
KR101920050B1 (ko) | 2018-11-19 |
KR20130124349A (ko) | 2013-11-13 |
RU2598644C2 (ru) | 2016-09-27 |
WO2012076831A1 (en) | 2012-06-14 |
AU2011340295A1 (en) | 2013-07-18 |
CA2819466A1 (en) | 2012-06-14 |
JP5702864B2 (ja) | 2015-04-15 |
ZA201304896B (en) | 2014-09-25 |
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Legal Events
Date | Code | Title | Description |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right |
Effective date of registration: 20170421 Address after: Lausanne Patentee after: AIKE Siabi Security Co.,Ltd. Address before: Swiss Cruz Roth Patentee before: Aerweiou Nicks Effective date of registration: 20170421 Address after: Swiss Cruz Roth Patentee after: Aerweiou Nicks Address before: American California Patentee before: Wei Defeng |
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TR01 | Transfer of patent right |