CN103330804A - Medicine for treating pains and fevers of terminal cancer patients and preparation method thereof - Google Patents

Medicine for treating pains and fevers of terminal cancer patients and preparation method thereof Download PDF

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CN103330804A
CN103330804A CN2013102588583A CN201310258858A CN103330804A CN 103330804 A CN103330804 A CN 103330804A CN 2013102588583 A CN2013102588583 A CN 2013102588583A CN 201310258858 A CN201310258858 A CN 201310258858A CN 103330804 A CN103330804 A CN 103330804A
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姜文
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Abstract

The invention aims to provide a non-narcotic medicine which can be taken for a long term and is used for treating pains and fevers of terminal cancer patients and a preparation method thereof. The medicine is prepared from the following raw materials in parts by weight: 10-20 parts of cinnabar, 9-30 parts of oyster shell, 10-20 parts of pseudo-ginseng, 10-25 parts of ginseng, 25-30 parts of glossy ganoderma, 18-30 parts of American ginseng, 9-12 parts of radix sophorae tonkinensis, 9-12 parts of red halloysite, 9-15 parts of barbary wolfberry fruit, 3-9 parts of pinellia tuber, 15-20 parts of radix astragali, 15-25 parts of glossy privet fruit, 15-20 parts of basic lead carbonate, 60-90 parts of gordon euryale seed, 10-20 parts of limonitum, 15-20 parts of Chinese yam, 10-25 parts of cinnamon and 150-200 parts of bitter wine. The preparation method is characterized by weighing the active pharmaceutical ingredients according to the ratio, putting the active pharmaceutical ingredients into an earthen pot, adding 1000ml of water to immerse the active pharmaceutical ingredients for 90 minutes, decocting the active pharmaceutical ingredients with soft fire for 60 minutes, filtering the decoction and taking the soup; then adding 800ml of water, decocting the active pharmaceutical ingredients with soft fire for 45 minutes, filtering the decoction and taking the soup; and combining the two soups and adding the bitter wine, thus obtaining the drug.

Description

Be used for the treatment of medicine of patients with advanced cancer pain and heating disease and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of medicine that is used for the treatment of patients with advanced cancer pain and heating disease and preparation method thereof.
Background technology
Cancer is because early discovery difficulty relatively generally is middle and advanced stage when patient goes to a doctor, treatment generally by perform the operation, put, chemotherapy alleviates, but behind the PD, the disease of generating heat pain can appear and.Patient generally spends in misery.
Pain, heating for cancer causes do not have suitable therapy at present, and antipyretic is invalid substantially, and the cold compress effect is too poor.
Summary of the invention
The object of the invention provides medicine that is used for the treatment of patients with advanced cancer pain and heating disease a kind of non-narcotic, that can take for a long time and preparation method thereof.
To achieve these goals, the present invention is by the following technical solutions:
A kind of medicine that is used for the treatment of patients with advanced cancer pain and heating disease, raw material by following weight parts is made: Cinnabaris 10~20, Concha Ostreae 9~30, Radix Notoginseng 10~20, Radix Ginseng 10~25, Ganoderma 25~30, Radix Panacis Quinquefolii 18~30, Radix Sophorae Tonkinensis 9~12, Halloysitum Rubrum 9~12, Fructus Lycii 9~15, the Rhizoma Pinelliae 3~9, the Radix Astragali 15~20, Fructus Ligustri Lucidi 15~25, English white 15~20, Semen Euryales 60~90, Limonitum 10~20, Rhizoma Dioscoreae 15~20, Cortex Cinnamomi 10~25, Bitters 150~200.
The above-mentioned medicine that is used for the treatment of patients with advanced cancer pain and heating disease, raw material by following weight parts is made: Cinnabaris 10, Concha Ostreae 20, Radix Notoginseng 18, Radix Ginseng 25, Ganoderma 30, Radix Panacis Quinquefolii 30, Radix Sophorae Tonkinensis 10, Halloysitum Rubrum 10, Fructus Lycii 15, the Rhizoma Pinelliae 5, the Radix Astragali 15, Fructus Ligustri Lucidi 20, English white 15, Semen Euryales 80, Limonitum 10, Rhizoma Dioscoreae 20, Cortex Cinnamomi 20, Bitters 180.
The preparation method of medicine of a kind of described treatment patients with advanced cancer pain and heating disease takes by weighing other crude drug except Bitters by said ratio, places in the marmite, add water 1000ml and soaked crude drug, soaked 90 minutes, little fire decocts 60 minutes, and filtration takes concoction; Add water 800ml again, little fire decocts 45 minutes, and filtration takes concoction; Merge medicine juice twice, add Bitters and get final product.
Instructions of taking: morning and evening twice decoction being taken warmly.
The present invention is made up of pure Chinese medicine, and the effect of each Chinese medicine is as follows:
Cinnabaris: meridian distribution of property and flavor, sweet, cold.Poisonous.The GUIXIN warp.Function cures mainly: calm the nerves, arresting convulsion makes eye bright, detoxifcation.Control demented, the palpitation with fear, vexed, the insomnia, dizzy, blurred vision, toxic swelling, skin infection, scabies.
Concha Ostreae: meridian distribution of property and flavor, salty, be slightly cold.Return liver, gallbladder, kidney channel.Function with cure mainly: tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.Be used for the palpitation with fear insomnia, vertigo and tinnitus, scrofula sucutaneous nodule , mass in the abdomen mass in the abdomen.The Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating.Be used for spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.
Radix Notoginseng: sweet in the mouth, little hardship, property is wet.Return liver, stomach, the heart, lung, large intestine channel.Function cures mainly: hemostasis; Blood looses; Analgesic therapy.Main falling pounces on congestive edema, thoracic obstruction angor, lump in the abdomen; The blood stasis amenorrhea; Dysmenorrhea; The cloudy stomachache of the stasis of blood in puerperal; Sore, carbuncle and painful swelling.
Radix Ginseng: property is flat, sweet in the mouth, little hardship, tepor.Return spleen, lung meridian, heart channel.Effect: strongly invigorating primordial QI, multiple arteries and veins takes off invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, the Fructus Alpiniae Oxyphyllae of calming the nerves admittedly.Cure mainly: impairment caused by overstrain is deficient, lack of appetite, asthenia, regurgitation are told food, stool lingering diarrhea, empty cough with asthma are short, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition, quench one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion and prolonged deficiency be multiple, the disease of all qi-blood-body fluid deficiencies.
Ganoderma: GUIXIN, liver, spleen, lung, the kidney Five Classics.Cure mainly asthenia, cough, asthma, insomnia, dyspepsia, malignant tumor etc.
Radix Panacis Quinquefolii: sweet, little hardship, cold.GUIXIN, lung, kidney channel.Function cures mainly: boosting qi and nourishing yin, clearing away heat and promoting production of body fluid.It is thanks to cloudy to be used for the deficiency of vital energy, interior-heat, and cough with asthma expectorant blood, deficiency-heat is tired tired, quenches one's thirst dryness of the mouth and throat.Radix Panacis Quinquefolii has the effect of resisting fatigue, antioxidation, anti-stress, anticoagulant, reduction blood coagulation, in addition, diabetics is regulated in addition the effect of blood glucose.
Radix Sophorae Tonkinensis: little have a bean stink smell, and flavor is extremely bitter.Function cures mainly: the detoxifcation of relieving inflammation or internal heat, reducing swelling and alleviating pain.Be used for throat gingival swelling and pain, cough due to lung-heat's excessive thirst, jaundice, constipation with heat retention.
Halloysitum Rubrum: nature and flavor with return through: sweet, sour, puckery, temperature.Return stomach, large intestine channel.Function with cure mainly: astringing intestine to stop diarrhea, the hemostasis, promoting tissue regeneration and ulcer healing.Be used for the chronic diarrhea chronic dysentery, it is hemorrhage to defecate, bleeding not during menses; The external treatment skin infection is not held back, eczema pus contamination.
Fructus Lycii: sweet in the mouth; Property is put down.Return Liver Channel; Kidney channel; Lung meridian.Nourishing the liver; Nourishing kidney; Lung moistening; Caused by liver and kidney deficiency; Have a dizzy spell; Visual unclear; Soreness of the waist and knees; Impotence and seminal emission; Cough due to consumptive disease; The taking fluids profusely of quenching one's thirst.
The Rhizoma Pinelliae: nature and flavor with return through suffering, temperature; Poisonous.Return spleen, stomach, lung meridian.Function with cure mainly: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Be used for the abundant expectoration cough with asthma, the phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, the syncope due to accumulation of phlegm headache, vomiting regurgitation, breast gastral cavity painful abdominal mass is vexed, globus hystericus; Give birth to external treatment carbuncle sucutaneous nodule.
The Radix Astragali: sweet in the mouth, slightly warm in nature is returned liver, spleen, lung, kidney channel.There are benefiting QI for strengthening the superficies, arresting sweating to take off, hold in the palm the effect of skin ulcer granulation promoting, inducing diuresis to remove edema admittedly.
Fructus Ligustri Lucidi: sweet, bitter, cool in nature.Liver, kidney channel.Liver and kidney tonifying; Crow must make eye bright.
English white: hot, sweet, cold.Poisonous.Return liver, spleen, stomach, large intestine channel.Dislike Orpimentum (Auripigmentum).[drug effect]: anticancer, the parasite killing of relieving internal heat is treated skin ulcer, the hemostasis of becoming silted up of dispelling.
Semen Euryales: sweet in the mouth, puckery, property is flat, and is nontoxic.Effect cures mainly: cure mainly rheumatic arthritis, back gonalgia.Invigorating the spleen and replenishing QI, the strong will of refreshing oneself makes people's normal hearing and eyesight.It is not hungry that clothes of a specified duration are made light of one's life by commiting suicide the people.Can also whet the appetite and help gas and the kidney invigorating, control frequency of micturition, seminal emission, purulent leukorrhea.It is edible to make powder, beneficial people.
 
Limonitum: sweet in the mouth is flat.Main cough with dyspnea, lump in the abdomen, blood closes, and leaks down, surplus pathogen.
Rhizoma Dioscoreae: sweet in the mouth, property is flat.Return spleen, lung, kidney channel.The spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.
Cortex Cinnamomi: hot, sweet, big heat.Return kidney, spleen, the heart, Liver Channel.Function cures mainly: it is supporing yang to mend fire, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.Be used for sexual impotence, cold womb, chills and pain of the waist and kness is suffered from a deficiency of the kidney and is done to breathe heavily, dizziness due to yang deficiency, the conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, dysmenorrhea.
Bitters: sour, bitter, go into liver, stomach warp, promoting blood circulation to remove blood stasis, promoting digestion and removing stagnation, the detumescence softening the hard mass, skin ulcer is treated in detoxifcation.
Beneficial effect of the present invention: all medicines of medicine of the present invention share, and have the analgesic effect of analgesia clinically, and patients with advanced cancer pain and heating disease are had excellent curative.Can not be addicted, can take for a long time.
The specific embodiment
Below in conjunction with specific embodiment the present invention is described in further details, following explanation only is exemplary, does not limit protection scope of the present invention.
Embodiment 1
Be used for the treatment of the medicine of patients with advanced cancer pain and heating disease in the present embodiment, made by the raw material of following weight parts: ZhuSand 10g, Concha Ostreae 20 g, Radix Notoginseng 18 g, Radix Ginseng 25 g, Ganoderma 30 g, Radix Panacis Quinquefolii 30 g, Radix Sophorae Tonkinensis 10 g, Halloysitum Rubrum 10 g, Fructus Lycii 15 g, the Rhizoma Pinelliae 5 g, the Radix Astragali 15 g, Fructus Ligustri Lucidi 20 g, English white 15 g, Semen Euryales 80 g, Limonitum 10 g, Rhizoma Dioscoreae 20 g, Cortex Cinnamomi 20 g, Bitters 180 g.
The preparation method of medicine for the treatment of patients with advanced cancer pain described in the present embodiment and heating disease takes by weighing other crude drug except Bitters by said ratio, places in the marmite, add water 1000ml and soaked crude drug, soaked 90 minutes, little fire decocts 60 minutes, and filtration takes concoction; Add water 800ml again, little fire decocts 45 minutes, and filtration takes concoction; Merge medicine juice twice, add Bitters and get final product.
Embodiment 2
The medicine that is used for the treatment of patients with advanced cancer pain and heating disease in the present embodiment, raw material by following weight parts is made: Cinnabaris 15g, Concha Ostreae 30 g, Radix Notoginseng 10 g, Radix Ginseng 20 g, Ganoderma 25 g, Radix Panacis Quinquefolii 25 g, Radix Sophorae Tonkinensis 9 g, Halloysitum Rubrum 9 g, Fructus Lycii 9 g, the Rhizoma Pinelliae 9 g, the Radix Astragali 20 g, Fructus Ligustri Lucidi 15 g, English white 20 g, Semen Euryales 60 g, Limonitum 15 g, Rhizoma Dioscoreae 15 g, Cortex Cinnamomi 15 g, Bitters 150 g.
Preparation method is with embodiment 1.
Embodiment 3
The medicine that is used for the treatment of patients with advanced cancer pain and heating disease in the present embodiment, raw material by following weight parts is made: Cinnabaris 20 g, Concha Ostreae 9 g, Radix Notoginseng 20 g, Radix Ginseng 10 g, Ganoderma 28 g, Radix Panacis Quinquefolii 18 g, Radix Sophorae Tonkinensis 12 g, Halloysitum Rubrum 12 g, Fructus Lycii 12 g, the Rhizoma Pinelliae 9 g, the Radix Astragali 18 g, Fructus Ligustri Lucidi 18 g, English white 18 g, Semen Euryales 90 g, Limonitum 20 g, Rhizoma Dioscoreae 18 g, Cortex Cinnamomi 10 g, Bitters 200 g.
Preparation method is with embodiment 1.
Clinical efficacy is summed up
One, physical data: patient's 200 examples, all cases all are terminal cancer, and diagnosis is clear and definite, has pain in various degree, with heating disease person 38 examples, and age 23-76 year.
Two, method of administration: morning and evening twice decoction being taken warmly.
Three, curative effect determinate standard:
(1) cancer pain curative effect judging standard:
1, produce effects: total pain relief in 24h, the patient does not feel the obvious pain of chest or hepatic region, do not have obviously feel sick, vomiting, discomfort such as dizzy, nervous, diet is general, sleep can;
2, effective: pain is partly alleviated in 24h, and sense chest or hepatic region mild pain can tolerate reluctantly during the patient, and time has and slightly feels sick, and does not have vomiting, and idol has giddy, discomfort such as nervous, and diet is poor slightly, and sleep is general;
3, invalid: pain does not have alleviation in 24h, and the patient still feels chest or hepatalgia, and nauseating, vomiting, discomfort such as dizzy, nervous are arranged, and diet is poor, and it is poor to sleep.
(2) cancer heating curative effect judging standard:
1, produce effects: heating is alleviated fully, and body temperature is normal after the medication;
2, effective: heating part is alleviated, and body temperature is high slightly after the medication, and most time is normal body temperature;
3, invalid: heating paresthesia does not have alleviation, and body temperature does not reduce.
Four, therapeutic effect:
1, Cancer pain Therapy the results are shown in Table 1, and table 1 medicine of the present invention as can be seen reaches 95.5% for the pain effective percentage that cancer causes.
Figure 2013102588583100002DEST_PATH_IMAGE001
2, the cancer fever therapy the results are shown in Table 2, and table 2 medicine of the present invention as can be seen reaches 97.37% for the heating effective percentage that cancer causes.
Figure 392483DEST_PATH_IMAGE002
Five, model case:
1, granddaughter scholar, 58 years old, breast carcinoma, CT makes a definite diagnosis through hospital, sharp ache, the patient cannot diet, and it is poor to sleep.Take medicine of the present invention, one day twice, each was once taken for the first time and fell asleep in back 2 hours sooner or later, second day a small amount of diet, and spirit takes a turn for the better, and still continues at present to take.
2, Mrs Li, 35 years old, pulmonary carcinoma, sharp ache.Take medicine of the present invention, one day twice, sooner or later each once, pain no longer after taking continues to take at present.
3, Jiang, the man, 70 years old, thymic carcinoma, chest pain, often vomiting, it is nervous that it is invalid to take antipyretic, takes medicine of the present invention after 2 days with heating paresthesia, and body temperature is normal, continues at present to take, and observes all rightly, and body temperature is normal always.
4, Zhang Ming, the man, 65, primary hepatocarcinoma, the patient is rest pain, sleep is disturbed, take medicine of the present invention after pain alleviate to some extent, bigger improvement is arranged when going to a doctor, continue now to take.

Claims (3)

  1. One kind be used for the treatment of patients with advanced cancer pain and the heating disease medicine, it is characterized in that being made by the raw material of following weight parts: Cinnabaris 10~20, Concha Ostreae 9~30, Radix Notoginseng 10~20, Radix Ginseng 10~25, Ganoderma 25~30, Radix Panacis Quinquefolii 18~30, Radix Sophorae Tonkinensis 9~12, Halloysitum Rubrum 9~12, Fructus Lycii 9~15, the Rhizoma Pinelliae 3~9, the Radix Astragali 15~20, Fructus Ligustri Lucidi 15~25, English white 15~20, Semen Euryales 60~90, Limonitum 10~20, Rhizoma Dioscoreae 15~20, Cortex Cinnamomi 10~25, Bitters 150~200.
  2. 2. according to the described medicine that is used for the treatment of patients with advanced cancer pain and heating disease of claim 1, it is characterized in that being made by the raw material of following weight parts: Cinnabaris 10, Concha Ostreae 20, Radix Notoginseng 18, Radix Ginseng 25, Ganoderma 30, Radix Panacis Quinquefolii 30, Radix Sophorae Tonkinensis 10, Halloysitum Rubrum 10, Fructus Lycii 15, the Rhizoma Pinelliae 5, the Radix Astragali 15, Fructus Ligustri Lucidi 20, English white 15, Semen Euryales 80, Limonitum 10, Rhizoma Dioscoreae 20, Cortex Cinnamomi 20, Bitters 180.
  3. 3. the preparation method of the medicine of a claim 1 or 2 described treatment patients with advanced cancer pain and heating disease, it is characterized in that: take by weighing other crude drug except Bitters by said ratio, place in the marmite, add water 1000ml and soaked crude drug, soaked 90 minutes, little fire decocts 60 minutes, and filtration takes concoction; Add water 800ml again, little fire decocts 45 minutes, and filtration takes concoction; Merge medicine juice twice, add Bitters and get final product.
CN2013102588583A 2013-06-26 2013-06-26 Medicine for treating pains and fevers of terminal cancer patients and preparation method thereof Pending CN103330804A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104623597A (en) * 2015-01-15 2015-05-20 姜文 Medicinal composition for treating pain and fever of cancer patient and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104623597A (en) * 2015-01-15 2015-05-20 姜文 Medicinal composition for treating pain and fever of cancer patient and preparation method thereof

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Application publication date: 20131002