CN103316264A - Medicine composition for treating hyperplasia of mammary glands - Google Patents

Medicine composition for treating hyperplasia of mammary glands Download PDF

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Publication number
CN103316264A
CN103316264A CN2013102749354A CN201310274935A CN103316264A CN 103316264 A CN103316264 A CN 103316264A CN 2013102749354 A CN2013102749354 A CN 2013102749354A CN 201310274935 A CN201310274935 A CN 201310274935A CN 103316264 A CN103316264 A CN 103316264A
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parts
herba
fructus
radix
rhizoma
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CN2013102749354A
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CN103316264B (en
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李华
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Gao Ping
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李华
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Abstract

The invention relates to a medicine composition for treating hyperplasia of mammary glands. The medicine composition is prepared from the following substances: piper cubeba, codonopsis pilosula, rhizoma atractylodis macrocephalae, rhodiola rosea, schisandra chinensis, eucommia ulmoides, radix achyranthis bidentatae, herba siegesbeckiae, medlar, sword bean, semen sesami nigrum, herba polygoni perfoliati, flos sophorae, medulla stachyuri, herba gendarussae, common bombax flower, cornus officinalis, smilax, semen cassiae, folium sauropi, morinda officinalis, caulis mahoniae, white hyacinth bean, rehmannia glutinosa, rhizoma polygonati, cichorium intybus, Chinese yam, rhizoma dioscoreae septemlobae, rhodiola rosea, hawthorn, peucedanum decursivum maxim, herba cistanche, momordica grosvenori, pterocephalus hookeri heck, lotus leaf, manchurian lilac bark, folium mori, flos chrysanthemi, rhizoma nelumbinis, flos sophorae, spina date seed, retinervus luffae fructus, raspberry, thlaspi arvense, radix paeoniae rubra, cortex moutan, safflower, corydalis tuber, fructus gardeniae, rheum officinale, concha arcae, cortex phellodendri, dandelion, fructus broussonetiae and semen celosiae. The medicine composition for treating hyperplasia of mammary glands provided by the invention has the characteristics of low cost, easiness in preparation, little toxic and side effects and obvious curative effect.

Description

A kind of pharmaceutical composition for the treatment of cyclomastopathy
Technical field
The present invention relates to drug world, specifically, relate to a kind of pharmaceutical composition for the treatment of cyclomastopathy.
Background technology
Cyclomastopathy is women's commonly encountered diseases, and China women's sickness rate has reached 30%-50%, and ratio is up to 90% in the mastopathy out-patient.Cyclomastopathy is the modal a kind of disease of Breast Surgery outpatient service, belong to neither also noninflammatory preneoplastic lesions of tumor, be mammary gland tissue and a matter in various degree hypertrophy and breast structure in quantity and modal unusual, often can form the lump river, main manifestations is mastalgia and lump.
Summary of the invention
The purpose of this invention is to provide a kind of pharmaceutical composition for the treatment of cyclomastopathy.
In order to realize purpose of the present invention, the invention provides a kind of pharmaceutical composition for the treatment of cyclomastopathy, it is made by the material of following weight proportioning: 25 parts of Fructus Litseae, 20 parts of Radix Codonopsis, 43 parts of the Rhizoma Atractylodis Macrocephalaes, 38 parts of Radix Rhodiolaes, 51 parts of Fructus Schisandrae Chinensis, 26 parts of the Cortexs Eucommiae, 36 parts of 37 parts of Herba Siegesbeckiaes of Radix Achyranthis Bidentatae, 27 parts of Fructus Lycii, 24 parts of Semen Canavaliaes, 28 parts of Semen Sesami Nigrums, 25 parts of Herba Polygoni cymosis, 33 parts in Flos Sophorae, 27 parts of Medulla Stachyuri (Medulla Helwingiae)s, 33 parts of Herba Gendarussaes, 24 parts of Flos Bombacis Malabaricis, 38 parts of Fructus Corni, 25 parts of Rhizoma Smilacis Chinensiss, 27 parts of Semen Cassiaes, 36 parts of Folium Sauropis, 32 parts of Radix Morindae Officinaliss, 33 parts of Caulis Mahoniaes, 27 parts of Semen Lablab Albums, 18 parts in Radix Rehmanniae Preparata, 22 parts of Rhizoma Polygonatis, 27 parts of Herba Cichoriis, 24 parts of 26 parts of Rhizoma Dioscoreae Septemlobaes of Rhizoma Dioscoreae, 35 parts of Radix Rhodiolaes, 40 parts of Fructus Crataegis, 23 parts of RADIX PEUCEDANI, 36 parts of Herba Cistanches, 26 parts of Fructus Momordicaes, 33 parts of Herba pterocephali, 36 parts on Folium Nelumbinis, 35 parts of Cortex Syingae Amurensiss, 38 parts on Folium Mori, 33 parts of Flos Chrysanthemis, 23 parts of Nodus Nelumbinis Rhizomatis, 31 parts in Flos Sophorae, 32 parts of Semen Ziziphi Spinosaes, 23 parts of Retinervus Luffae Fructuss, 36 parts of 28 parts of Herba Thlaspiss of Fructus Rubi, 28 parts of Radix Paeoniae Rubra, 26 parts of Cortex Moutans, 21 parts on Flos Carthami, 28 parts of Rhizoma Corydalis, 35 parts of Fructus Gardeniaes, 36 parts of Radix Et Rhizoma Rhei, 25 parts of Concha Arcaes, 32 parts of Cortex Phellodendris, 17 parts of Herba Taraxacis, 33 parts of 35 parts of Fructus Broussonetiaes and Semen Celosiae.
Preferably, described pharmaceutical composition can be tablet, dispersible tablet, powder or decoction.
The pharmaceutical composition for the treatment of cyclomastopathy of the present invention has the advantages that cost is low, preparation is easy, toxic and side effects is little, curative effect is showing.
The specific embodiment
Embodiment 1:
Take by weighing Fructus Litseae 25 grams, Radix Codonopsis 20 grams, the Rhizoma Atractylodis Macrocephalae 43 grams, Radix Rhodiolae 38 grams, Fructus Schisandrae Chinensis 51 grams, the Cortex Eucommiae 26 grams, Radix Achyranthis Bidentatae 37 gram Herba Siegesbeckiaes 36 grams, Fructus Lycii 27 grams, Semen Canavaliae 24 grams, Semen Sesami Nigrum 28 grams, Herba Polygoni cymosi 25 grams, Flos Sophorae 33 grams, Medulla Stachyuri (Medulla Helwingiae) 27 grams, Herba Gendarussae 33 grams, Flos Bombacis Malabarici 24 grams, Fructus Corni 38 grams, Rhizoma Smilacis Chinensis 25 grams, Semen Cassiae 27 grams, Folium Sauropi 36 grams, Radix Morindae Officinalis 32 grams, Caulis Mahoniae 33 grams, Semen Lablab Album 27 grams, Radix Rehmanniae Preparata 18 grams, Rhizoma Polygonati 22 grams, Herba Cichorii 27 grams, Rhizoma Dioscoreae 26 gram Rhizoma Dioscoreae Septemlobaes 24 grams, Radix Rhodiolae 35 grams, Fructus Crataegi 40 grams, RADIX PEUCEDANI 23 grams, Herba Cistanches 36 grams, Fructus Momordicae 26 grams, Herba pterocephali 33 grams, Folium Nelumbinis 36 grams, Cortex Syingae Amurensis 35 grams, Folium Mori 38 grams, Flos Chrysanthemi 33 grams, Nodus Nelumbinis Rhizomatis 23 grams, Flos Sophorae 31 grams, Semen Ziziphi Spinosae 32 grams, Retinervus Luffae Fructus 23 grams, Fructus Rubi 28 gram Herba Thlaspiss 36 grams, Radix Paeoniae Rubra 28 grams, Cortex Moutan 26 grams, Flos Carthami 21 grams, Rhizoma Corydalis 28 grams, Fructus Gardeniae 35 grams, Radix Et Rhizoma Rhei 36 grams, Concha Arcae 25 grams, Cortex Phellodendri 32 grams, Herba Taraxaci 17 grams, Fructus Broussonetiae 35 grams and Semen Celosiae 33 grams, add 7000 ml waters, 70 ℃ of lower heating 3 hours, filter.In filtering residue, add 4000 ml waters, 60 ℃ of lower heating 2 hours, filter.Merge filtrate twice, and be concentrated into 600 milliliters, namely get decoction of the present invention.
Experimental example
Choose cyclomastopathy patient 50 examples, age 19-50 year, 40.5 years old mean age; Most at the upper outside existence one flat lump of breast, by it beans size is arranged, tough hard tubercle can have tenderness, and owe clearly on the lump border, with the surrounding tissue adhesion; One-sided or the bilateral of breast swell and pain, pain and lump are relevant with menstrual cycle; Take the photograph other mastopathy such as eliminating breast carcinoma, mammary gland fibroma such as sheet through ultrasound diagnosis, infrared ray galactophore scanning, mammography; Course of disease January-1 year; Get rid of allergic constitution or to drug allergy person, be associated with serious conscience disease of hematopoietic system or psychotic.
Decoction with preparation among the embodiment 1 is treated.Each oral 50 milliliters, respectively take 1 time every day sooner or later, treated continuously 1 month.
The efficacy determination method
Standard determination curative effect by Society of Surgery of China's breast disease special topic group appointment.Cure: lump disappears, and mastalgia disappears, 3 months recidivists not after the drug withdrawal; Produce effects: the lump maximum gauge dwindles more than 1/2, mastalgia disappearance person; Effectively: the lump maximum is dwindled less than more than 1/2, and mastalgia alleviates or the lump maximum gauge dwindles more than 1/2, and mastalgia is the alleviator not; Nothing: lump does not dwindle or increases on the contrary hardening person, or simple mastalgia is alleviated and lump does not dwindle.
Through treatment, 50 routine patient's lumps disappear, and mastalgia disappears, and therefore 3 months recidivists not after the drug withdrawal all meet the standard of healing.

Claims (2)

1. pharmaceutical composition for the treatment of cyclomastopathy is characterized in that it is made by the material of following weight proportioning: 25 parts of Fructus Litseae, 20 parts of Radix Codonopsis, 43 parts of the Rhizoma Atractylodis Macrocephalaes, 38 parts of Radix Rhodiolaes, 51 parts of Fructus Schisandrae Chinensis, 26 parts of the Cortexs Eucommiae, 36 parts of 37 parts of Herba Siegesbeckiaes of Radix Achyranthis Bidentatae, 27 parts of Fructus Lycii, 24 parts of Semen Canavaliaes, 28 parts of Semen Sesami Nigrums, 25 parts of Herba Polygoni cymosis, 33 parts in Flos Sophorae, 27 parts of Medulla Stachyuri (Medulla Helwingiae)s, 33 parts of Herba Gendarussaes, 24 parts of Flos Bombacis Malabaricis, 38 parts of Fructus Corni, 25 parts of Rhizoma Smilacis Chinensiss, 27 parts of Semen Cassiaes, 36 parts of Folium Sauropis, 32 parts of Radix Morindae Officinaliss, 33 parts of Caulis Mahoniaes, 27 parts of Semen Lablab Albums, 18 parts in Radix Rehmanniae Preparata, 22 parts of Rhizoma Polygonatis, 27 parts of Herba Cichoriis, 24 parts of 26 parts of Rhizoma Dioscoreae Septemlobaes of Rhizoma Dioscoreae, 35 parts of Radix Rhodiolaes, 40 parts of Fructus Crataegis, 23 parts of RADIX PEUCEDANI, 36 parts of Herba Cistanches, 26 parts of Fructus Momordicaes, 33 parts of Herba pterocephali, 36 parts on Folium Nelumbinis, 35 parts of Cortex Syingae Amurensiss, 38 parts on Folium Mori, 33 parts of Flos Chrysanthemis, 23 parts of Nodus Nelumbinis Rhizomatis, 31 parts in Flos Sophorae, 32 parts of Semen Ziziphi Spinosaes, 23 parts of Retinervus Luffae Fructuss, 36 parts of 28 parts of Herba Thlaspiss of Fructus Rubi, 28 parts of Radix Paeoniae Rubra, 26 parts of Cortex Moutans, 21 parts on Flos Carthami, 28 parts of Rhizoma Corydalis, 35 parts of Fructus Gardeniaes, 36 parts of Radix Et Rhizoma Rhei, 25 parts of Concha Arcaes, 32 parts of Cortex Phellodendris, 17 parts of Herba Taraxacis, 33 parts of 35 parts of Fructus Broussonetiaes and Semen Celosiae.
2. the pharmaceutical composition for the treatment of cyclomastopathy according to claim 1 is characterized in that, described pharmaceutical composition can be tablet, dispersible tablet, powder or decoction.
CN201310274935.4A 2013-07-03 2013-07-03 Medicine composition for treating hyperplasia of mammary glands Expired - Fee Related CN103316264B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113876834A (en) * 2021-10-30 2022-01-04 佛山市欣康迈科技有限公司 Application of traditional Chinese medicine extract in preparation of traditional Chinese medicine product for resisting hyperplasia of mammary glands

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101085301A (en) * 2007-06-29 2007-12-12 胡玉翠 Oral administration traditional Chinese medicine composition for treating mammary cancer
CN101129976A (en) * 2007-09-03 2008-02-27 仲鹏 Orally taken traditional Chinese medicine composition for treating mammary cancer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101085301A (en) * 2007-06-29 2007-12-12 胡玉翠 Oral administration traditional Chinese medicine composition for treating mammary cancer
CN101129976A (en) * 2007-09-03 2008-02-27 仲鹏 Orally taken traditional Chinese medicine composition for treating mammary cancer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113876834A (en) * 2021-10-30 2022-01-04 佛山市欣康迈科技有限公司 Application of traditional Chinese medicine extract in preparation of traditional Chinese medicine product for resisting hyperplasia of mammary glands

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