CN103316037B - Treatment diarrhea of pigs and the mineral immunopotentiating agent for improving pig production performance - Google Patents
Treatment diarrhea of pigs and the mineral immunopotentiating agent for improving pig production performance Download PDFInfo
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- CN103316037B CN103316037B CN201210077226.2A CN201210077226A CN103316037B CN 103316037 B CN103316037 B CN 103316037B CN 201210077226 A CN201210077226 A CN 201210077226A CN 103316037 B CN103316037 B CN 103316037B
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- 239000003795 chemical substances by application Substances 0.000 title claims abstract description 42
- 230000002434 immunopotentiative effect Effects 0.000 title claims abstract description 38
- 229910052500 inorganic mineral Inorganic materials 0.000 title claims abstract description 34
- 239000011707 mineral Substances 0.000 title claims abstract description 34
- 206010012735 Diarrhoea Diseases 0.000 title claims abstract description 28
- 241000282887 Suidae Species 0.000 title claims abstract description 15
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 11
- 238000002360 preparation method Methods 0.000 claims abstract description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 18
- 229960000892 attapulgite Drugs 0.000 claims description 11
- 229910052625 palygorskite Inorganic materials 0.000 claims description 11
- GUJOJGAPFQRJSV-UHFFFAOYSA-N dialuminum;dioxosilane;oxygen(2-);hydrate Chemical compound O.[O-2].[O-2].[O-2].[Al+3].[Al+3].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O GUJOJGAPFQRJSV-UHFFFAOYSA-N 0.000 claims description 10
- 229910052901 montmorillonite Inorganic materials 0.000 claims description 10
- 239000004575 stone Substances 0.000 claims description 10
- 238000001354 calcination Methods 0.000 claims description 6
- 239000002994 raw material Substances 0.000 claims description 5
- 239000003814 drug Substances 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 3
- 231100000678 Mycotoxin Toxicity 0.000 abstract description 5
- 239000002636 mycotoxin Substances 0.000 abstract description 5
- 235000010755 mineral Nutrition 0.000 description 23
- 241000282898 Sus scrofa Species 0.000 description 14
- 241001465754 Metazoa Species 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 5
- 239000011782 vitamin Substances 0.000 description 5
- 235000013343 vitamin Nutrition 0.000 description 5
- 229940088594 vitamin Drugs 0.000 description 5
- 229930003231 vitamin Natural products 0.000 description 5
- 150000003722 vitamin derivatives Chemical class 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 238000000227 grinding Methods 0.000 description 4
- 238000001179 sorption measurement Methods 0.000 description 4
- 238000010521 absorption reaction Methods 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 208000001848 dysentery Diseases 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 208000005577 Gastroenteritis Diseases 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 206010028140 Mucous stools Diseases 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 230000000680 avirulence Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 229930195730 Aflatoxin Natural products 0.000 description 1
- XWIYFDMXXLINPU-UHFFFAOYSA-N Aflatoxin G Chemical compound O=C1OCCC2=C1C(=O)OC1=C2C(OC)=CC2=C1C1C=COC1O2 XWIYFDMXXLINPU-UHFFFAOYSA-N 0.000 description 1
- 208000031295 Animal disease Diseases 0.000 description 1
- 241000122824 Aspergillus ochraceus Species 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 206010004016 Bacterial diarrhoea Diseases 0.000 description 1
- 241001235572 Balantioides coli Species 0.000 description 1
- 241000244203 Caenorhabditis elegans Species 0.000 description 1
- 241000224483 Coccidia Species 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 229920001503 Glucan Polymers 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
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- 241001469654 Lawsonia <weevil> Species 0.000 description 1
- 241001071864 Lethrinus laticaudis Species 0.000 description 1
- NIPNSKYNPDTRPC-UHFFFAOYSA-N N-[2-oxo-2-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 NIPNSKYNPDTRPC-UHFFFAOYSA-N 0.000 description 1
- 208000030852 Parasitic disease Diseases 0.000 description 1
- 241000702670 Rotavirus Species 0.000 description 1
- 206010041954 Starvation Diseases 0.000 description 1
- 239000005409 aflatoxin Substances 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 208000007456 balantidiasis Diseases 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000004927 clay Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- BVTBRVFYZUCAKH-UHFFFAOYSA-L disodium selenite Chemical class [Na+].[Na+].[O-][Se]([O-])=O BVTBRVFYZUCAKH-UHFFFAOYSA-L 0.000 description 1
- XLMJRFCCCWFQRE-SJRQCXNHSA-N ecboline Chemical compound C([C@H]1[C@]2(O)O3)CCN1C(=O)CN2C(=O)[C@]3(C(C)C)NC(=O)[C@@H](CN(C)[C@@H]1C2)C=C1C1=C3C2=CNC3=CC=C1 XLMJRFCCCWFQRE-SJRQCXNHSA-N 0.000 description 1
- 231100000284 endotoxic Toxicity 0.000 description 1
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- 238000005516 engineering process Methods 0.000 description 1
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- 239000003925 fat Substances 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 208000024386 fungal infectious disease Diseases 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 230000008105 immune reaction Effects 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 230000001524 infective effect Effects 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 229920006008 lipopolysaccharide Polymers 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 229910052680 mordenite Inorganic materials 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 229910021647 smectite Inorganic materials 0.000 description 1
- 235000015921 sodium selenite Nutrition 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- MBMQEIFVQACCCH-UHFFFAOYSA-N trans-Zearalenon Natural products O=C1OC(C)CCCC(=O)CCCC=CC2=CC(O)=CC(O)=C21 MBMQEIFVQACCCH-UHFFFAOYSA-N 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- MBMQEIFVQACCCH-QBODLPLBSA-N zearalenone Chemical compound O=C1O[C@@H](C)CCCC(=O)CCC\C=C\C2=CC(O)=CC(O)=C21 MBMQEIFVQACCCH-QBODLPLBSA-N 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Fodder In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to a kind of mineral immunopotentiating agent treated diarrhea of pigs and improve pig production performance, it has good suction-operated to mycotoxin.The invention further relates to the preparation method of the mineral immunopotentiating agent.
Description
Technical field
The present invention relates to a kind of mineral immunopotentiating agent treated diarrhea of pigs and improve pig production performance, it has good
Gastric mucosal protection function, suction-operated (absorption to bacterium, the absorption to mycotoxin, it is endotoxic to body absorption etc.) and
The effect of heavy metal in de- feed.
Background technology
Diarrhea of pigs is clinically a kind of common disease, and pathogenic factor is more complicated.Have plenty of because feeding management is not good at, have
It is because bacterium or virus infection cause.Popular diarrhea of pigs when winter and the early spring, symptom is infected with pig epidemic diarrhea and pig
Property gastroenteritis it is closely similar, for raiser, if pig has infected this disease, whole pig farm can all fall ill in a short time, long
Just slowly calmed down up to 1-2 months, very big economic loss can be caused.
The reason for causing grice diarrhoea can be generally divided into two kinds of avirulence factor and causative factors.It is specific and
Speech, causes the reason for swinery is suffered from diarrhoea to be usually：(1) bacterial diarrhea：Escherichia coli, clostridieum welchii enteritis, swine dysentery bacillus,
Interior Lawsonia.(2) virus diarrhea：Transmissible gastroenteritis, epidemic diarrhea, rotavirus, PRV.(3) post
Infested property diarrhoea：Roundworm, coccidia, whipworm, balantidium Coli.(4) non-infective agent：Temperature, hypoglycemia (inanition abdomen
Rush down), daily ration antigen allergic diarrhea (soybean allergy), avirulence dysentery characterized by white mucous stool (iron-deficient is suffered from diarrhoea, enzyme and stomach subacidity dysentery characterized by white mucous stool).
Prior art treats diarrhea of pigs using Western medicine or Chinese medicine.
Immunopotentiating agent is that a class can improve immune and nonspecific immune reaction the material of animal autospecific, these
Material can strengthen the ability (Anderson, 1992) of animal disease resistant poison, bacterium, fungi and parasitic infection.At present in actual life
The immunopotentiating agent applied in production is mainly included：The constituent (lipopolysaccharides, lipopeptid, glycoprotein) of bacterium, β -1,3 Portugals gather
Sugar, β -1,3/1,6 glucans, oligosaccharide, peptide, blood fat, vitamin, mineral matter and some can strengthen the artificial of animal immune ability
Synthetic.Numerous studies show in recent years, and immunopotentiating agent can strengthen animal overall immune ability, improve the productivity of animal
Energy.
Mineral matter is a kind of immunopotentiating agent, because it has adsorption capacity, can adsorb various bacteriums, virus and a huge sum of money
Belong to element etc., so as to reach the prevention or therapeutic action to infectious diseases, strengthen animal immunizing power, improve animal productiong
Energy.
The content of the invention
It is an object of the invention to provide a kind of mineral immunopotentiating agent that can be treated diarrhea of pigs and improve pig production performance,
It is consisted of the following composition：
Modenite (MORDENITE) 40-45 parts by weight,
Montmorillonite (SMECTITE) 10-15 parts by weight,
Attapulgite (ATTAPULGITE CLAY) 25-35 parts by weight,
Medical stone (MAIFANITUM) 5-8 parts by weight,
B B-complex 2-2.5 parts by weight.
Preferably, the present invention provides a kind of mineral immunopotentiating agent that can be treated diarrhea of pigs and improve pig production performance,
It is consisted of the following composition：
Modenite 42-43 parts by weight,
Montmorillonite 12-14 parts by weight,
Attapulgite 28-32 parts by weight,
Medical stone 6-7 parts by weight,
The parts by weight of B B-complex 2.5.
The present invention also provides a kind of preparation method of the mineral immunopotentiating agent, and it comprises the following steps：
By modenite, montmorillonite and attapulgite, with such as disk mill, 150-200 mesh is crushed to；
By medical stone in 850 DEG C of calcinings, and soaked with 50% acetic acid, be then crushed to 150-200 mesh；
Formula material and B B-complex are pre-mixed.
B B-complex of the present invention can be any commercially available piggy B B-complex.
The present invention further provides a kind of purposes of above-mentioned mineral immunopotentiating agent in treatment diarrhea of pigs medicine is prepared.
The present invention further provides a kind of above-mentioned mineral immunopotentiating agent in the feed addictive for preparing treatment diarrhea of pigs
Purposes.
The feed addition of raising pig generation performance is being prepared the present invention further provides a kind of above-mentioned mineral immunopotentiating agent
Purposes in agent.
The present invention further provides a kind of feed addictive, it contains mineral immunopotentiating agent of the present invention.
Product of the present invention can be added directly in mixed feed, or can also be added with other known pig's feeds
Agent is used in conjunction with.
Embodiment
Embodiment 1
Take 40 kilograms of modenite, 10 kilograms of montmorillonite, 25 kilograms of attapulgite, co-grinding to 200 mesh；Take medical stone
5 kilograms, it is soaked in 850 DEG C of calcinings and with 50% acetic acid, 200 mesh are then crushed to；Raw material after crushing and piglet are answered
2 kilograms of premixings of vitamin are closed, mineral immunopotentiating agent 1 of the present invention is made.
Embodiment 2
Take 45 kilograms of modenite, 15 kilograms of montmorillonite, 35 kilograms of attapulgite, co-grinding to 150 mesh；Take medical stone
8 kilograms, it is soaked in 850 DEG C of calcinings and with 50% acetic acid, 150 mesh are then crushed to；Raw material after crushing and piglet are answered
2.5 kilograms of premixings of vitamin are closed, mineral immunopotentiating agent 2 of the present invention is made.
Embodiment 3
Take 42 kilograms of modenite, 12 kilograms of montmorillonite, 28 kilograms of attapulgite, co-grinding to 180 mesh；Take medical stone
6 kilograms, it is soaked in 850 DEG C of calcinings and with 50% acetic acid, 180 mesh are then crushed to；Raw material after crushing and piglet are answered
2.5 kilograms of premixings of vitamin are closed, mineral immunopotentiating agent 3 of the present invention is made.
Embodiment 4
Take 43 kilograms of modenite, 14 kilograms of montmorillonite, 32 kilograms of attapulgite, co-grinding to 200 mesh；Take medical stone
7 kilograms, it is soaked in 850 DEG C of calcinings and with 50% acetic acid, 200 mesh are then crushed to；Raw material after crushing and piglet are answered
2.5 kilograms of premixings of vitamin are closed, mineral immunopotentiating agent 4 of the present invention is made.
Above-mentioned piglet B B-complex is purchased from Chengdu Ke Fei feed technologies Co., Ltd.
Experimental example 1
Certain feed research institute is entrusted, the mineral immunopotentiating agent 4 obtained by embodiment 4 is carried out to mycotoxin adsorption ability
Experiment.As a result show：100% is adsorbed as to aflatoxin, 87% is adsorbed as to zearalenone, to Aspergillus ochraceus
Toxin is absorbed as 70%, is adsorbed as 100% to ergotoxin, 91% is adsorbed as to fumonism.
It can be seen that mineral immunopotentiating agent of the present invention has good mycotoxin adsorption ability.
Experimental example 2
The mineral immunopotentiating agent 4 that 54 size pig farms are obtained using the embodiment of the present invention 4, its production effect statistics
Show：The total effective rate for treating diarrhea of weaned piglets syndrome is 94.74%, and cure rate is 42.11%.Certain pig farm is to producing abdomen
The sucking pig rushed down is gavaged (3g/ times) using immunopotentiating agent 4, and it is 88.9% that cure rate is gavaged twice.
Experimental example 3
The nest of Du great Chang sodium selenites 2 normally weaned selected from 25 ages in days, is randomly divided into 2 groups by totally 22.One group is control
Group, feed per ton adds zinc oxide；Another group is test group, and feed per ton adds the mineral immunopotentiating agent 4 of 1% (weight).
Observe weaned piglets and diarrhoea ability.
As a result with analysis：
The experimental observation result of table 1 and com-parison and analysis
As shown in Table 1, the test group of mineral immunopotentiating agent 4 is with the addition of compared with control group, adding weight is improved, expect meat
Than declining, diarrhoea number of times has also declined, and this shows that mineral immunopotentiating agent of the present invention can reduce the diarrhea disease percentage of piglet
And improve the production performance of piglet.
The mineral immunopotentiating agent 1-3 that the present invention is also obtained using embodiment 1-3, according to experimental example 1-3 identical sides
Method further demonstrates the effect of the mineral immunopotentiating agent.In the case where being similarly per ton 1% addition, each immunopotentiating agent
Show the good adsorption capacity to mycotoxin；Its cure rate to diarrhea of weaned piglets syndrome is respectively
40.15%th, 39.46% and 45.23%, the cure rate gavaged twice is respectively 82.3%, 80.9% and 91.2%；And be respectively provided with
Effect ground anti diar rhea ability and the ability for improving weaned piglets.
Claims (7)
1. a kind of mineral immunopotentiating agent that can be treated diarrhea of pigs and improve pig production performance, it is consisted of the following composition：
Modenite 40-45 parts by weight,
Montmorillonite 10-15 parts by weight,
Attapulgite 25-35 parts by weight,
5-8 kilograms of medical stone,
B B-complex 2-2.5 parts by weight,
Wherein, the preparation method of described mineral immunopotentiating agent comprises the following steps：
Modenite, montmorillonite and attapulgite are crushed to 150-200 mesh with pulverizer；
By medical stone in 850 DEG C of calcinings, and soaked with 50% acetic acid, be then crushed to 150-200 mesh；
Raw material after crushing and B B-complex are pre-mixed.
2. the mineral immunopotentiating agent according to claim 1 that diarrhea of pigs can be treated and pig production performance is improved, its by
Following component is constituted：
Modenite 42-43 parts by weight,
Montmorillonite 12-14 parts by weight,
Attapulgite 28-32 parts by weight,
Medical stone 6-7 parts by weight,
The parts by weight of B B-complex 2.5.
3. mineral immunopotentiating agent according to claim 1, wherein the pulverizer is disk mill.
4. purposes of the mineral immunopotentiating agent in treatment diarrhea of pigs medicine is prepared according to any one of claim 1 or 2.
5. the mineral immunopotentiating agent according to any one of claim 1 or 2 is preparing the feed addictive for the treatment of diarrhea of pigs
In purposes.
6. the mineral immunopotentiating agent according to any one of claim 1 or 2 adds in the feed for preparing raising pig generation performance
Plus the purposes in agent.
7. a kind of feed addictive, it contains mineral immunopotentiating agent as claimed in claim 1 or 2.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210077226.2A CN103316037B (en) | 2012-03-21 | 2012-03-21 | Treatment diarrhea of pigs and the mineral immunopotentiating agent for improving pig production performance |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210077226.2A CN103316037B (en) | 2012-03-21 | 2012-03-21 | Treatment diarrhea of pigs and the mineral immunopotentiating agent for improving pig production performance |
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| Publication Number | Publication Date |
|---|---|
| CN103316037A CN103316037A (en) | 2013-09-25 |
| CN103316037B true CN103316037B (en) | 2017-09-26 |
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| CN201210077226.2A Expired - Fee Related CN103316037B (en) | 2012-03-21 | 2012-03-21 | Treatment diarrhea of pigs and the mineral immunopotentiating agent for improving pig production performance |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111956510B (en) * | 2020-09-15 | 2023-07-07 | 厦门惠盈动物科技有限公司 | Talcum powder for animals and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1068940A (en) * | 1991-07-29 | 1993-02-17 | 中科院长沙农业现代化研究所 | Preparing method for pig feed china medicine stone compound additive |
| CN1088745A (en) * | 1992-12-26 | 1994-07-06 | 北京市潮白河新技术研究所 | Compound premixed feed |
| CN1718078A (en) * | 2004-07-07 | 2006-01-11 | 王彦明 | Additives for fodder in husbandry, and its application |
-
2012
- 2012-03-21 CN CN201210077226.2A patent/CN103316037B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1068940A (en) * | 1991-07-29 | 1993-02-17 | 中科院长沙农业现代化研究所 | Preparing method for pig feed china medicine stone compound additive |
| CN1088745A (en) * | 1992-12-26 | 1994-07-06 | 北京市潮白河新技术研究所 | Compound premixed feed |
| CN1718078A (en) * | 2004-07-07 | 2006-01-11 | 王彦明 | Additives for fodder in husbandry, and its application |
Non-Patent Citations (2)
| Title |
|---|
| 凹凸棒石、蒙脱石及其复合物对断奶仔猪肠道的保护作用研究;孟艳莉;《中国优秀硕士学位论文全文数据库农业科技辑》;20111015(第10期);第9、33页，尤其是第9页第2.2.2节，第33页第4.1节 * |
| 添加广西沸石和麦饭石饲喂生长肥育猪的试验研究;夏中生等;《广西农学院学报》;19911231;第10卷(第2期);第43-52页，尤其是第1.1节，第50页第2.6、3节 * |
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Address after: 518048, 20E, Hubei Hotel, 9003 Binhe Avenue, Futian District, Guangdong, Shenzhen Applicant after: Guangdong Bao Bio Technology Co.,Ltd. Address before: 510163 building 171-173, No. two middle middle road, Liwan District bridge, Guangzhou, Guangdong Province, six Applicant before: Guangdong Bao Bio Technology Co.,Ltd. Address after: 510163 building 171-173, No. two middle middle road, Liwan District bridge, Guangzhou, Guangdong Province, six Applicant after: Guangdong Bao Bio Technology Co.,Ltd. Address before: 510163 building 171-173, No. two middle middle road, Liwan District bridge, Guangzhou, Guangdong Province, six Applicant before: Guangzhou livestock Biotechnology Co.,Ltd. Address after: 510163 building 171-173, No. two middle middle road, Liwan District bridge, Guangzhou, Guangdong Province, six Applicant after: Guangzhou livestock Biotechnology Co.,Ltd. Address before: 515041 Guangdong Province, Shantou city Longhu District East Tyrone Industrial Park in the northwest side of society Applicant before: SHANTOU CHUBAO BIOLOGICAL SCIENCE & TECHNOLOGY Co.,Ltd. |
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Free format text: CORRECT: APPLICANT; FROM: GUANGZHOU CHUBAO BIOLOGICAL TECHNOLOGY CO., LTD. TO: GUANGDONG CHUBAO BIOLOGICAL TECHNOLOGY CO., LTD. Free format text: CORRECT: APPLICANT; FROM: SHANTOU XUBAO BIOLOGICAL SCIENCE AND TECHNOLOGY CO., LTD. TO: GUANGZHOU CHUBAO BIOLOGICAL TECHNOLOGY CO., LTD. |
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Inventor after: Zhao Helan Inventor after: Chen Yunian Inventor before: Zhao Helan |
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Granted publication date: 20170926 Termination date: 20190321 |