CN103300363A - Anti-fatigue traditional Chinese medicine capsule and preparation method thereof - Google Patents

Anti-fatigue traditional Chinese medicine capsule and preparation method thereof Download PDF

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CN103300363A
CN103300363A CN2013102057086A CN201310205708A CN103300363A CN 103300363 A CN103300363 A CN 103300363A CN 2013102057086 A CN2013102057086 A CN 2013102057086A CN 201310205708 A CN201310205708 A CN 201310205708A CN 103300363 A CN103300363 A CN 103300363A
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traditional chinese
chinese medicine
capsule
dietary fiber
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CN103300363B (en
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赵薇
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HUBEI SUN PHARMACEUTICAL TECHNOLOGY Co Ltd
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HUBEI SUN PHARMACEUTICAL TECHNOLOGY Co Ltd
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Abstract

The invention provides an anti-fatigue traditional Chinese medicine capsule which comprises the following components in parts by weight: 27-33 parts of a herba epimedii extract, 30-40 parts of dietary fiber, 27-33 parts of an Eucommia ulmoides extract, 1-4 parts of an American ginseng extract, 30-40 parts of a grape seed extract, appropriate parts of an auxiliary material gelatin, and further 10 parts of vitamin C. The anti-fatigue traditional Chinese medicine capsule provided by the invention has the functions of tonifying yang of liver and kidney, strengthening the bones and muscles, expelling wind-damp, adjusting the digestive system, adjusting blood balance, tonifying qi and yang, preventing fatigue and resisting oxidation. The capsule tested can remarkably improve the sexual function of males and improve the quality of sexual life.

Description

Traditional Chinese medicine health capsule of a kind of antifatigue and preparation method thereof
Technical field:
The present invention relates to the Chinese medicine preparation technical field, be specially traditional Chinese medicine health capsule of a kind of antifatigue and preparation method thereof
Background technology:
According to the survey report that the property expert provides, the sexual life of appropriateness can make the male sex's testosterone secretion amount increase, and the effect of testosterone can make the muscular of the male sex, improves the hematopoietic potential of marrow.For the women, if can in the sexual life of being everlasting, obtain fully satisfied, the physiological function of ovary and endocrine ability will strengthen, its skin will become more soft and smooth and it is glossy, it is more glossy that hair can become, it is more optimistic that spirit can become, so word saying so arranged: the sexual life of rule is best in the world beautician.American scientist confirms after deliberation, can be often and spouse's sexual life of being satisfied with, and the man suffers from the possibility that prostate cancer, woman suffer from breast cancer will be much smaller.Suitable sexual life also has a benefit to enhance metabolism exactly, prevents early ageing, prevents brain aging.According to the investigation to long-lived population, all long-lived persons often have and the sexuality of rule.Can determine thus, sexual life and the longevity of appropriateness have certain positive connection.Sexual life can also be confirmed from the negative to the benefit of health, according to from the scientific research personnel, divorce, unmarried woman and compare wedding person, suffer from the cancer of the uterus the death rate the former be the latter 2-3 doubly.Aspect the deaths from heart disease rate, the divorcee is also apparently higher than the married.
In other words, the sexual life of rule does not have any difference to benefit and the physical training of health, has a lot of Physical Trainings to be beneficial to health, and psychology is not but had direct effect.And sexual life has unique advantage in this respect.Can enjoy the joyful people of sexual life and be not easy to be subject to lonely and lonely torment, compare with the celibate, suffer from the ratio of not controlling not disease, mental disease, suicide much lower.Because the former does not have sense of depression psychologically, its aging course also than the latter slowly many.
In the U.S. reproductive medicine association annual meeting of holding recently, brainstrust has been delivered an investigation result about male sex's sexual desire.The result shows, because the large rhythm of life of modern life pressure is fast, just feels more tired, unable to do what one wishes people in middle age, is the problem that generally makes male sex's worry, and can affects the marital relations of most people.So some men begin to take the vigour medicine, after vigour has been eaten shortterm effect is arranged, but have side effects, the infringement health.
Food and nutrient promote sexual desire, modulability impression and enhancing sexual function, become the direction of people's research.
Summary of the invention:
The technical problem to be solved in the present invention provides a kind of traditional Chinese medicine health capsule of antifatigue, in order to submitting quality of life to, and the preparation method of this traditional Chinese medicine health capsule.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
A kind of traditional Chinese medicine health capsule of antifatigue comprises the following weight component: barrenwort 27-33 part extract, dietary fiber 30-40 part, bark of eucommia 27-33 part extract, American Ginseng 1-4 part extract, grape pip 30-40 part, auxiliary material gelatin are an amount of.
Described composition by weight also comprises 10 parts of vitamin Cs
As preferred, comprise the following weight component: 30 parts of extracts of barrenwort, 35 parts of dietary fibers, 30 parts of extracts of the bark of eucommia, 1.5 parts of extracts of American Ginseng, 35 parts of grape pips, 2 parts in auxiliary material gelatin.
The preparation method of the traditional Chinese medicine health capsule of a kind of antifatigue of the present invention, other are characterised in that, comprise the steps:
One, barrenwort, the bark of eucommia, American Ginseng supercritical carbon dioxide extracting extract three times, and each 2 hours, reclaim carbon dioxide, it is 1.1~1.2 thick paste that filtrate is concentrated into 70 ℃ of condition relative densities;
Two, supercritical carbon dioxide extracting extracted three times after grape pip was pulverized, and each 2 hours, reclaim carbon dioxide, it is 1.1~1.2 thick paste that filtrate is concentrated into 70 ℃ of condition relative densities;
Three, the thick paste of step 1 and step 2 is dry respectively, 100 orders are pulverized, and sieve, and get dry thing;
Four, dietary fiber 100 orders are pulverized, and sieve;
Five, with dry thing and dietary fiber, vitamin C, obtain active constituents of medicine, this active component is directly made gelatine capsule or is mixed and made into capsule with the medicine acceptable carrier.
Carbon dioxide abstraction carries that extraction temperature is controlled at 35 ℃ in the process among the present invention, and pressure is controlled at 8 MPas.
Barrenwort
Kidney-replenishing, strengthening the bones and muscles, wines used as antirheumatic.Be used for impotence and seminal emission, the muscles and bones impotence is soft, arthralgia due to wind-dampness, numbness contracture; Climacteric hypertension.
Be used for that impotence due to deficiency of the kidney, seminal emission premature ejaculation, waist knee impotence are soft, cold extremities with aversion to cold.Control the impotence something lost and let out, can join the product such as thizoma curculiginis, dogwood fruit, saline cistanche; Control waist knee impotence soft, can join the product such as the bark of eucommia, Morinda officinalis, rhizoma cibotii.Be used for numbness and ache of cold dampness or spasm of limbs numb.Controls arthralgia due to wind-dampness and be partial to cold-dampness person, and numb limb is meciless or muscles and bones contraction etc., can with the compatibilities such as the root of Chinese clematis, Morinda officinalis, Chinese cassia tree, Radix Angelicae Sinensis, Ligusticum wallichii.
Barrenwort is the cauline leaf of the multiple barrenwort such as Berberidaceae plant barrenwort, arrow leaf barrenwort, Wushan barrenwort, korean epimedium herb.The barrenwort perennial herb, summer, autumn gather, and extract cauline leaf, remove impurity, dry.
The barrenwort aerial part is long 20 to 40 centimetres, stem thin rod shape, rib smoothly or slightly, tool gloss.Two times trifoliolate leaves; The tool long handle; The vanelets oval, long 3 to 7 centimetres, wide 2 to 5 centimetres, edge tool thorn-like serration; Upper surface green or yellow green, slightly glossy, without hair, the lower surface celadon has pubescence along vein, and the arteries and veins base is longer.The nearly keratin of blade is more crisp.Gas is little, mildly bitter flavor.
Long 25 to 45 centimetres of the lascivious sheep leaves of pulse plants of arrow leaf aerial part, a trifoliolate leaf, long 4 to 10 centimetres of leaflet, the hard thorn-like of leaf edge sawtooth is about 2 millimeters, following table mask open wool or near without hair.The blade keratin is firmly crisp.
Long 40 to 70 centimetres of Wushan barrenwort aerial part, a trifoliolate leaf, the vanelets lanceolar, wide 2 to 4 centimetres, be about 5 times into this.
The korean epimedium herb aerial part is about 35 centimetres.Two times trifoliolate leaves, commodity mostly are the monolithic leaflet, the vanelets width egg shape, the edge sawtooth is furry, blade film matter.
All take, colour band green person many without rhizome, blade as good.
The barrenwort trophic analysis:
HERBA EPIMEDII mainly contains icariine etc., and the HERBA EPIMEDII extract has the effect of male sex hormone sample, can promote gonopoiesis, hypoglycemic; Be improved hypophysis--the effect of interrenal system function, and can form by enhancing antibody.
Difference according to concocting method is divided into barrenwort and barrenwort processed.Barrenwort is namely got crude drug, removes impurity and branch stalk, gets leaf, cleans, and slightly moistens chopping, drying.Barrenwort processed is divided into again suet system, butter system, wine system, frying.
In the medicinal material storage drying receptacle after the process of preparing Chinese medicine, airtight, put shady and cool dry place, protection against the tide.
Barrenwort is fit to the crowd:
1. cold infertile, the deficiency of yang hypertension of suitable impotence, palace, climacteric disease crowd.
Fire excess from yin deficiency penis ultroerection easily act person prohibit clothes.
The barrenwort dietary function:
The barrenwort flavor is hot, sweet, warm in nature; Return Liver Channel; The light gas of body is male, can rise and can fall
Cure mainly impotence, the seminal emission premature ejaculation, cold sperm is sterile, the frequent micturition incontinence, dyspnea and cough due to deficiency of the kidney, soreness and weakness of waist and knees, the muscles and bones contraction is anxious, arthralgia due to wind-dampness, hemiplegia, four limbs are meciless.
The bark of eucommia
The bark of eucommia is the dry bark of the Eucommiaceae plant bark of eucommia (Eucommia ulmoides Oliver), is Chinese famous and precious tonic herb.Tool filling liver kidney, strengthening the bones and muscles, many effects such as hypotensive, antiabortive.Shennong's Herbal is classified as top grade.Call its " cure mainly waist and knee, bowl spares, beneficial vital essence, hard muscles and bones, wet except itching under cloudy, dribbling urination.Clothes are made light of one's life by commiting suicide anti-old for a long time." bark of eucommia is Chinese peculiar medicinal material, its medicinal history is long, has a wide range of applications clinical.Oneself finds nearly 14 kinds of bark of eucommia platymisciums on earth so far, and they became extinct in succession in continent and Europe afterwards.The bark of eucommia that is present in China is that the Eucommiaceae bark of eucommia belongs to the Relict Plant of only depositing, and it not only has very high economic worth, and all has very important scientific value for all many-sides such as origin of research angiosperm phylogeny and Chinese Flora.It is existing that oneself is put into " Chinese Plants Red Data Book-rare endangered plants " first volume as rare plant.
Both at home and abroad the expert has carried out repeatedly careful research to bark of eucommia composition, and bark of eucommia free amino acid is few, a small amount of protein that contains, be with most foodstuffs like adequate proteins, namely can be hydrolyzed 8 seed amino acids that detect needed by human.Measure 15 kinds of contained mineral elements of the bark of eucommia, the trace elements such as zinc, copper, iron have wherein been arranged, reached the macroelements such as calcium, phosphorus, potassium, magnesium.
The bark of eucommia has filling liver kidney, and rubbish in the body is removed in strengthening the bones and muscles, strengthen the human body cell metabolism, prevent that muscle skeleton is aging, the balance human blood-pressure, the decomposer inner cholesterol, reduce body fat, recover blood vessel elasticity, the diuresis heat-clearing, broad-spectrum antiseptic, stimulating central nervous system improves white blood cell count, strengthens the remarkable efficacy such as body immunity.
American Ginseng
American Ginseng in the traditional Chinese medical science has following feature:
[meridian distribution of property and flavor] sweet, little hardship, cold.The thoughts of returning home, lung, kidney channel.
[function cures mainly] boosting qi and nourishing yin, clearing heat and promoting fluid.Be used for the deficiency of vital energy thanks to cloudy, interior heat is coughed and is breathed heavily phlegm blood, and abnormal heat is tired tired, quenches one's thirst dryness of the mouth and throat.American Ginseng has antifatigue, anti-oxidant, the anti-effect that stress, suppress platelet aggregation, reduces blood clotting, in addition, the diabetic is regulated in addition the effect of blood sugar.
[chemical composition] rhizome contains Chikusetsusaponin V, Rb1, Rb2, Rc, Rd, Re, Rg1 and panicled fameflower root saponin F11(pseudoginsenosideF11), still contain 18 seed amino acids such as arginine, aspartic acid; Contain again volatile oil, resin etc.
[pharmacological action] zoopery has sedation to brain, vital center is then had the excitation of moderate.
Grape pip
Extract its effective ingredient (former blue and white plain oligomer, english abbreviation OPC) through high-tech approach and be aided with that vitamin C is refining to be formed.Grape seed extract (OPC) is a kind of efficient free radical scavenger.Can remove poisonous free radical in the human body, the protection human cell tissue exempts to be prevented the diseases relevant with free radical of kind more than 80 such as allergy, cancer, aging by the oxidative damage of free radical.Vitamin C can reduce fragility and the permeability of capillary, corrects irritated pathological change, also is radicals scavenging and antioxidant simultaneously, cooperates grape seed extract (OPC), to correct allergy, the physique texts is more remarkable.Human common anaphylactia comprises bronchial astehma.Because the human normal metabolic processes, smoking, edible fat and salting down fire-cure meat, be inflamed, some cancer therapy drug, hypnotic, computer radiate, agricultural chemicals, organic matter rot, the ozone in the air pollution, chemical carcinogen, atmosphere etc. also can both produce free radical.If free radical can not in time be got rid of, easily cause the diseases relevant with free radical of kind more than 80 such as allergy, cancer, aging.Such as: headache, dizzy, decrease of platelet, hypoimmunity, arthritis, cataract, the retinitis, headstroke, person of a serious nature may cause cancer.Grape pip anti-ageing, antioxidant effect is very good, it be vitamin C and vitamin E 30-50 doubly.
Dietary fiber
Dietary fiber is the mixture that comprises the Multiple components such as cellulose, hemicellulose, lignin, pectin and soluble polysaccharide.Dietary fiber has multiple physiological hygiene function, and is closely related with health, lacks dietary fiber and can cause various diseases, so contain extremely consumer's the favor of goods of dietary fiber.The edible fiber products dietary fiber extensively is present in fruit, vegetables, cereal, beans and other the water plant.By the research that deepens continuously to dietary fiber, its various physiological hygiene functions are also constantly excavated.China is a large agricultural country, and dietary fiber extensively is present in the plant.
1, the definition of dietary fiber and composition
The mixture that dietary fiber is comprised of the Various Complex organic substance but not single entities have suitable intestines defaecation, regulate one or more physiological functions such as control blood sugar concentration, reducing blood lipid.Dietary fiber is a kind of edible vegetalitas composition, but not animal component.The dietary fiber wide material sources are present in the materials such as vegetables, fruit, coarse food grain, coarse cereals, agar, pectin.
2, dietary fiber and health
2.1 promote the colon function, prevent colon cancer
Nineteen sixty South Africa scholar Oettle has found contacting of dietary fiber and human cancer first, has after this carried out again large quantity research and test, and the result thinks that high fiber, low-fat diet can reduce the incidence of colon cancer.Colon cancer may cause owing to effects such as certain stimulus or poisonous substance such as nitrosamine and phenol, ammonia.These Toxics stop long in colon, will be to intestines wall generation toxic action.Studies show that, because the dietary fiber water imbibition is strong, relatively increased the volume and weight of ight soil, diluted carcinogen concentrations in the intestines, thereby play the effect of anti-cancer; Secondly, dietary fiber accelerates the emptying of intestinal contents, has reduced the generation of microorganism in the intestines or has changed carcinogenic chance, has shortened the action time that carcinogenic substance contacts with the intestines wall, therefore can reduce the incidence of colon cancer.
2.2 treatment diabetes
Diabetes are a kind of whole body chronic metabolic disease that determined by inherent cause, because the relative or absolute deficiency of insulin causes that carbohydrate, fat and protein metabolism are disorderly in the body, are characterized in hyperglycaemia and glycosuria.Studies show that recently, food fiber has and falls hypoglycemic effect, and wherein the water-soluble fibre effect is larger, such as bean gum, pectin, mushroom taro polysaccharide etc.Hypoglycemic mechanism of action can fall in pectin: pectin absorbs moisture, forms the gel filtration system in enteron aisle, changes nutrient and comprises digesting and assimilating of monose and disaccharides; Pectin can reduce the secretion of gastrointestinal hormone " gastric inhibitory potypeptide ", and the glucose absorption rate is reduced.Therefore, eat the health that rich pectous fruit is of value to diabetes patient's health more.
2.3 prevent coronary heart disease
Can control because coronary heart disease, especially the water-soluble dietary fiber more remarkable effect that blood cholesterol levels raises and causes by daily meals adjustment.This is because dietary fiber has the effect of absorption cholesterol on the one hand, makes cholesterol be difficult for seeing through intestinal mucosa and absorbs; On the other hand, dietary fiber can partly be blocked the intestines liver circulation of bile acid and cholesterol, accelerates cholate, cholic acid etc. from defecate, thereby reduces cholic acid and cholesterol levels in the blood, plays the effect that prevents and treats coronary heart disease.
2.4 detoxication
The mechanism of action of dietary fiber detoxifcation is: 1. promotes gastrointestinal motility, and in colon, plays stronger osmosis, thus the concentration of having diluted the medicine in the gastrointestinal contents, food additives and harmful chemical; 2. shorten intestinal contents by the time of enteron aisle, reduce the colon internal pressure, shorten the solution time that connects of enteral prods and intestines wall; 3. noxious material is wrapped up; 4. with the combination of metal cation, the illeffects of antagonism chemicals and food additives.Delay directly or indirectly, reduce digesting and assimilating of external harmful substance by these mechanism, play the hypotoxic effect of falling.
2.5 antiobesity action. after dietary fiber enters stomach and intestine, because it can absorb moisture and make volumetric expansion, increase satiety, reduce food-intake, thereby reach the purpose of fat-reducing.
In a word, dietary fiber is inseparable with health, and dietary fiber intake deficiency can cause the generation of various diseases.China to dietary fiber research relatively a little later, more because propaganda strength is inadequate, its health care is also rarely known by the people.China is populous, and along with the growth of various rich man's disease populations, believes that the dietary fiber enhanced products necessarily has more vast potential for future development.
The pharmaceutical compositions of compatibility of the present invention has following good effect through checking:
The tonifying liver kidney yang, strengthening the bones and muscles, wines used as antirheumatic, regulate digestive system, regulate the blood balance, boosting qi and nourishing yin, antifatigue, anti-oxidant, can obviously improve male's sexual, improve life quality through test.
Embodiment specifically:
The traditional Chinese medicine health capsule of a kind of antifatigue provided by the present invention comprises the following weight component: 30 parts of extracts of barrenwort, 35 parts of dietary fibers, 30 parts of extracts of the bark of eucommia, 1.5 parts of extracts of American Ginseng, 2 parts in 35 parts, 10 parts vitamin Cs of grape pip, auxiliary material gelatin.
The preparation method of the traditional Chinese medicine health capsule of a kind of antifatigue of the present invention, other are characterised in that, comprise the steps:
One, barrenwort, the bark of eucommia, American Ginseng supercritical carbon dioxide extracting extract three times, and each 2 hours, reclaim carbon dioxide, it is 1.1~1.2 thick paste that filtrate is concentrated into 70 ℃ of condition relative densities;
Two, supercritical carbon dioxide extracting extracted three times after grape pip was pulverized, and each 2 hours, reclaim carbon dioxide, it is 1.1~1.2 thick paste that filtrate is concentrated into 70 ℃ of condition relative densities;
Three, the thick paste of step 1 and step 2 is dry respectively, 100 orders are pulverized, and sieve, and get dry thing;
Four, dietary fiber 100 orders are pulverized, and sieve;
Five, with dry thing and dietary fiber, vitamin C, obtain active constituents of medicine, this active component is directly made gelatine capsule or is mixed and made into capsule with the medicine acceptable carrier.
Carbon dioxide abstraction carries that extraction temperature is controlled at 35 ℃ in the process among the present invention, and pressure is controlled at 8 MPas.
The above is embodiments of the invention only, is not limited to patent of invention, and for a person skilled in the art, the present invention can have various modifications and variations.Allly within the spirit and principle of invention, any modification of doing, be equal to replacement, improvement etc., all should be included within the claim scope of invention.

Claims (5)

1. the traditional Chinese medicine health capsule of an antifatigue, it is characterized in that, comprise the following weight component: barrenwort 27-33 part extract, dietary fiber 30-40 part, bark of eucommia 27-33 part extract, American Ginseng 1-4 part extract, grape pip 30-40 part, auxiliary material gelatin are an amount of.
2. the traditional Chinese medicine health capsule of a kind of antifatigue according to claim 1 is characterized in that, described composition by weight also comprises 10 parts of vitamin Cs
3. the traditional Chinese medicine health capsule of a kind of antifatigue according to claim 1 and 2, it is characterized in that, comprise the following weight component: 30 parts of extracts of barrenwort, 35 parts of dietary fibers, 30 parts of extracts of the bark of eucommia, 1.5 parts of extracts of American Ginseng, 35 parts of grape pips, 2 parts in auxiliary material gelatin.
4. the preparation method of the traditional Chinese medicine health capsule of a kind of antifatigue according to claim 2, other are characterised in that, comprise the steps:
One, barrenwort, the bark of eucommia, American Ginseng supercritical carbon dioxide extracting extract three times, and each 2 hours, reclaim carbon dioxide, it is 1.1~1.2 thick paste that filtrate is concentrated into 70 ℃ of condition relative densities;
Two, supercritical carbon dioxide extracting extracted three times after grape pip was pulverized, and each 2 hours, reclaim carbon dioxide, it is 1.1~1.2 thick paste that filtrate is concentrated into 70 ℃ of condition relative densities;
Three, the thick paste of step 1 and step 2 is dry respectively, 100 orders are pulverized, and sieve, and get dry thing;
Four, dietary fiber 100 orders are pulverized, and sieve;
Five, with dry thing and dietary fiber, vitamin C, obtain active constituents of medicine, this active component is directly made gelatine capsule or is mixed and made into capsule with the medicine acceptable carrier.
5. preparation method according to claim 4, other are characterised in that; Carbon dioxide abstraction carries that extraction temperature is controlled at 35 ℃ in the process, and pressure is controlled at 8 MPas.
CN201310205708.6A 2013-05-29 2013-05-29 Anti-fatigue traditional Chinese medicine capsule and preparation method thereof Expired - Fee Related CN103300363B (en)

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Publication number Priority date Publication date Assignee Title
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