CN103298507B - 采用线性洛仑兹力致动的无针射流注射系统递送固体和/或流体 - Google Patents
采用线性洛仑兹力致动的无针射流注射系统递送固体和/或流体 Download PDFInfo
- Publication number
- CN103298507B CN103298507B CN201180058911.4A CN201180058911A CN103298507B CN 103298507 B CN103298507 B CN 103298507B CN 201180058911 A CN201180058911 A CN 201180058911A CN 103298507 B CN103298507 B CN 103298507B
- Authority
- CN
- China
- Prior art keywords
- solid
- actuator
- needle
- storage
- delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
- A61M5/3015—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules for injecting a dose of particles in form of powdered drug, e.g. mounted on a rupturable membrane and accelerated by a gaseous shock wave or supersonic gas flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/332—Force measuring means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/35—Communication
- A61M2205/3546—Range
- A61M2205/3561—Range local, e.g. within room or hospital
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/35—Communication
- A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
- A61M2205/3584—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using modem, internet or bluetooth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
- A61M5/427—Locating point where body is to be pierced, e.g. vein location means using ultrasonic waves, injection site templates
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39105310P | 2010-10-07 | 2010-10-07 | |
| US61/391,053 | 2010-10-07 | ||
| US40535510P | 2010-10-21 | 2010-10-21 | |
| US61/405,355 | 2010-10-21 | ||
| PCT/US2011/055443 WO2012048268A2 (en) | 2010-10-07 | 2011-10-07 | Delivery of a solid body and/or a fluid using a linear lorentz-force actuated needle-free jet injection system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103298507A CN103298507A (zh) | 2013-09-11 |
| CN103298507B true CN103298507B (zh) | 2015-08-26 |
Family
ID=45044687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201180058911.4A Expired - Fee Related CN103298507B (zh) | 2010-10-07 | 2011-10-07 | 采用线性洛仑兹力致动的无针射流注射系统递送固体和/或流体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8821434B2 (enExample) |
| EP (2) | EP3403682A1 (enExample) |
| JP (1) | JP5934710B2 (enExample) |
| CN (1) | CN103298507B (enExample) |
| WO (1) | WO2012048268A2 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7833189B2 (en) | 2005-02-11 | 2010-11-16 | Massachusetts Institute Of Technology | Controlled needle-free transport |
| US8398583B2 (en) | 2008-07-09 | 2013-03-19 | Massachusetts Institute Of Technology | Method and apparatus for extraction of a sample from a sample source |
| WO2011028719A2 (en) | 2009-09-01 | 2011-03-10 | Massachusetts Institute Of Technology | Nonlinear system identification techniques and devices for discovering dynamic and static tissue properties |
| US9333060B2 (en) | 2009-12-15 | 2016-05-10 | Massachusetts Institute Of Technology | Plaque removal and differentiation of tooth and gum |
| CN103298507B (zh) | 2010-10-07 | 2015-08-26 | 麻省理工学院 | 采用线性洛仑兹力致动的无针射流注射系统递送固体和/或流体 |
| WO2012048277A2 (en) | 2010-10-07 | 2012-04-12 | Massachusetts Institute Of Technology | Injection methods using a servo-controlled needle-free injector |
| ITMI20132067A1 (it) | 2013-12-11 | 2015-06-12 | Dante Lorini | Apparecchiatura per l'inoculazione transdermica di medicamenti |
| US9782549B2 (en) * | 2014-10-22 | 2017-10-10 | Ethicon, Inc. | Distance indicators for medicinal spray devices |
| EP3037119A1 (en) * | 2014-12-23 | 2016-06-29 | Hipra Scientific, S.L.U. | Device for administering medicinal products |
| EP3040036B1 (de) * | 2014-12-29 | 2017-10-11 | Erbe Elektromedizin GmbH | Instrumentenkopf, Applikationsinstrument mit entsprechendem Instrumentenkopf und Applikationssystem |
| PL3040101T3 (pl) * | 2014-12-29 | 2017-08-31 | Erbe Elektromedizin Gmbh | Urządzenie zasilające do wytwarzania impulsowego strumienia płynu, system aplikacyjny z urządzeniem zasilającym i pamięć czytelna dla komputera |
| GB201501697D0 (en) * | 2015-02-02 | 2015-03-18 | Glide Pharmaceutical Technologies Ltd | Injection device |
| JP6583747B2 (ja) | 2015-09-29 | 2019-10-02 | 大日本印刷株式会社 | インプリント用のモールドおよびその製造方法 |
| US10737032B2 (en) * | 2015-11-25 | 2020-08-11 | Portal Instruments, Inc. | Needle-free transdermal injection device |
| US10842467B2 (en) * | 2015-12-15 | 2020-11-24 | Portal Instruments, Inc. | Biospecimen extraction apparatus |
| CN105943365B (zh) * | 2016-05-31 | 2018-04-17 | 张岩 | 电子针灸无痛针疗仪及染料 |
| JP2020501846A (ja) * | 2016-12-21 | 2020-01-23 | ダイナミック マグネティクス,エルエルシー | 自動注入器に動力供給するために使用される磁気ドライバデバイス |
| JP7328970B2 (ja) | 2017-09-12 | 2023-08-17 | ポータル インストルメンツ, インク. | 回転モータ式経皮注射装置 |
| KR102209394B1 (ko) | 2018-04-20 | 2021-01-29 | 경상대학교산학협력단 | 마이크로젯 약물 전달 시스템 |
| CN116407710A (zh) * | 2018-07-25 | 2023-07-11 | 株式会社大赛璐 | 注入器、以及使用该注入器向注入对象的细胞内注入包含生物分子的溶液的注入方法 |
| US12270015B2 (en) * | 2018-10-19 | 2025-04-08 | Nutech Ventures | Bioprinter devices, systems and methods for printing soft gels for the treatment of musculoskeletal and skin disorders |
| FR3092495B1 (fr) * | 2019-02-07 | 2021-11-26 | Oreal | Dispositif d’injection sans aiguille |
| JP7530177B2 (ja) * | 2020-01-31 | 2024-08-07 | 朝日インテック株式会社 | 薬液注入装置 |
| KR102513098B1 (ko) * | 2020-11-06 | 2023-03-23 | 주식회사 제이시스메디칼 | 무침 주사기 |
| CA3211236A1 (en) * | 2021-03-12 | 2022-09-15 | Keith Webb | Automatic needle-free injector container unit system |
| CN113384778A (zh) * | 2021-06-10 | 2021-09-14 | 苏芮 | 一种可控的无针注射装置 |
| CN116637255B (zh) * | 2023-04-23 | 2024-06-07 | 卓优医疗(苏州)有限公司 | 一种用于无针注射装置的微剂量调节方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5879327A (en) * | 1994-04-06 | 1999-03-09 | Moreau Defarges Alain | Needleless jet injection device |
| CN101128230A (zh) * | 2005-02-11 | 2008-02-20 | 麻省理工学院 | 表面注射装置 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW360548B (en) * | 1993-04-08 | 1999-06-11 | Powderject Res Ltd | Products for therapeutic use |
| US5865795A (en) * | 1996-02-29 | 1999-02-02 | Medi-Ject Corporation | Safety mechanism for injection devices |
| WO2000043058A1 (en) * | 1999-01-22 | 2000-07-27 | Powderject Research Limited | Method of enhancing needleless transdermal powdered drug delivery |
| US6258062B1 (en) * | 1999-02-25 | 2001-07-10 | Joseph M. Thielen | Enclosed container power supply for a needleless injector |
| US6224567B1 (en) * | 1999-09-08 | 2001-05-01 | Cambridge Biostability Limited | Modified disposable injector device |
| GB0100756D0 (en) * | 2001-01-11 | 2001-02-21 | Powderject Res Ltd | Needleless syringe |
| GB0125506D0 (en) | 2001-10-24 | 2001-12-12 | Weston Medical Ltd | Needle free injection method and apparatus |
| US6939323B2 (en) | 2001-10-26 | 2005-09-06 | Massachusetts Institute Of Technology | Needleless injector |
| US7429258B2 (en) | 2001-10-26 | 2008-09-30 | Massachusetts Institute Of Technology | Microneedle transport device |
| AU2003272279B2 (en) | 2002-09-06 | 2007-04-26 | Massachusetts Institute Of Technology | Measuring properties of an anatomical body |
| JP2006524120A (ja) * | 2003-04-21 | 2006-10-26 | ストラテージェント ライフ サイエンシズ | マイクロジェットで反復的に薬物を搬送する装置および方法 |
| EP1684238A1 (de) * | 2005-01-21 | 2006-07-26 | Swisscom Mobile AG | Identifikationsverfahren und System und dafür geeignete Vorrichtung |
| US20060258986A1 (en) * | 2005-02-11 | 2006-11-16 | Hunter Ian W | Controlled needle-free transport |
| US7833189B2 (en) * | 2005-02-11 | 2010-11-16 | Massachusetts Institute Of Technology | Controlled needle-free transport |
| JP2008535541A (ja) * | 2005-03-04 | 2008-09-04 | ストラタジェント ライフ サイエンシーズ, インコーポレイテッド | マイクロジェットデバイスおよび薬剤供給方法 |
| US8998881B2 (en) * | 2005-08-10 | 2015-04-07 | Alza Corporation | Method for delivering drugs to tissue under microjet propulsion |
| US7704704B2 (en) * | 2005-09-28 | 2010-04-27 | The Texas A&M University System | Implantable system for glucose monitoring using fluorescence quenching |
| WO2007058966A1 (en) * | 2005-11-11 | 2007-05-24 | Massachusetts Institute Of Technology | Controlled needle-free eye injector |
| WO2007061896A1 (en) * | 2005-11-17 | 2007-05-31 | Zogenix, Inc. | Delivery of viscous formulations by needle-free injection |
| WO2008001377A2 (en) | 2006-06-28 | 2008-01-03 | Perf-Action Technologies Ltd. | Needleless injections for administering compositions to the skin |
| US20080097335A1 (en) * | 2006-08-04 | 2008-04-24 | Allergan, Inc. | Ocular implant delivery assemblies |
| AU2007290354A1 (en) | 2006-09-01 | 2008-03-06 | Massachusetts Institute Of Technology | Needle-free injector device with autoloading capability |
| JP2008206477A (ja) * | 2007-02-27 | 2008-09-11 | National Cardiovascular Center | 無針注射器を用いた細胞播種法 |
| DK2146733T3 (da) * | 2007-03-14 | 2021-01-11 | Arch Biosurgery Inc | Treatment of leaky or damaged tight junctions and enhancing extracellular matrix |
| US8915866B2 (en) * | 2008-01-18 | 2014-12-23 | Warsaw Orthopedic, Inc. | Implantable sensor and associated methods |
| WO2009153729A1 (en) * | 2008-06-19 | 2009-12-23 | Koninklijke Philips Electronics N.V. | Parenteral medicament delivery device |
| US8398583B2 (en) | 2008-07-09 | 2013-03-19 | Massachusetts Institute Of Technology | Method and apparatus for extraction of a sample from a sample source |
| WO2011028716A1 (en) | 2009-09-01 | 2011-03-10 | Massachusetts Institute Of Technology | Nonlinear system identification technique for testing the efficacy of skin care products |
| WO2011028719A2 (en) | 2009-09-01 | 2011-03-10 | Massachusetts Institute Of Technology | Nonlinear system identification techniques and devices for discovering dynamic and static tissue properties |
| US8257295B2 (en) * | 2009-09-21 | 2012-09-04 | Alcon Research, Ltd. | Intraocular pressure sensor with external pressure compensation |
| US9333060B2 (en) | 2009-12-15 | 2016-05-10 | Massachusetts Institute Of Technology | Plaque removal and differentiation of tooth and gum |
| CN103298507B (zh) | 2010-10-07 | 2015-08-26 | 麻省理工学院 | 采用线性洛仑兹力致动的无针射流注射系统递送固体和/或流体 |
| WO2012048277A2 (en) | 2010-10-07 | 2012-04-12 | Massachusetts Institute Of Technology | Injection methods using a servo-controlled needle-free injector |
-
2011
- 2011-10-07 CN CN201180058911.4A patent/CN103298507B/zh not_active Expired - Fee Related
- 2011-10-07 EP EP18177310.2A patent/EP3403682A1/en not_active Withdrawn
- 2011-10-07 WO PCT/US2011/055443 patent/WO2012048268A2/en not_active Ceased
- 2011-10-07 JP JP2013532987A patent/JP5934710B2/ja not_active Expired - Fee Related
- 2011-10-07 US US13/269,322 patent/US8821434B2/en active Active
- 2011-10-07 EP EP11788243.1A patent/EP2621565B1/en not_active Not-in-force
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5879327A (en) * | 1994-04-06 | 1999-03-09 | Moreau Defarges Alain | Needleless jet injection device |
| CN101128230A (zh) * | 2005-02-11 | 2008-02-20 | 麻省理工学院 | 表面注射装置 |
| CN101132821A (zh) * | 2005-02-11 | 2008-02-27 | 麻省理工学院 | 无针透皮传送装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2621565B1 (en) | 2018-07-11 |
| WO2012048268A2 (en) | 2012-04-12 |
| CN103298507A (zh) | 2013-09-11 |
| EP2621565A1 (en) | 2013-08-07 |
| JP2013539688A (ja) | 2013-10-28 |
| US8821434B2 (en) | 2014-09-02 |
| US20120095435A1 (en) | 2012-04-19 |
| EP3403682A1 (en) | 2018-11-21 |
| JP5934710B2 (ja) | 2016-06-15 |
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| CN103269737B (zh) | 使用伺服控制的无针注射器的注射方法 | |
| JP5113532B2 (ja) | 無針式経皮輸送装置 | |
| US9308326B2 (en) | Controlled needle-free transport | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150826 Termination date: 20211007 |
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| CF01 | Termination of patent right due to non-payment of annual fee |