CN103285336B

CN103285336B - Chinese medicinal preparation for treating aplastic anemia

Info

Publication number: CN103285336B
Application number: CN201310262311.0A
Authority: CN
Inventors: 李宣儒; 孔晓红
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-06-27
Filing date: 2013-06-27
Publication date: 2014-11-26
Anticipated expiration: 2033-06-27
Also published as: CN103285336A

Abstract

The invention discloses a Chinese medicinal preparation for treating aplastic anemia. The Chinese medicinal preparation consists of red ginseng, radix pseudostellariae, parched white atractylodes rhizome, colla corii asini, white poria, angelica sinensis, ligusticum wallichii, fried madder, white paeony root, salviae miltiorrhizae, dried radix rehmanniae, radix curcumae, mulberry, dipsacus root, lumbricus, rhizoma corydalis, fingered citron, fructus schizandrae and the like. According to the Chinese medicinal preparation disclosed by the invention, the aplastic anemia is treated by the adoption of traditional Chinese medicaments; the Chinese medicinal preparation is a pure Chinese preparation; the Chinese medicinal preparation acts quickly, and clinical symptoms disappear quickly; and the Chinese medicinal preparation has few toxic and side effects, short in treating course, light in pain and low in cost.

Description

A kind of Chinese medicine preparation for the treatment of aplastic anemia

technical field:

The present invention discloses a kind of Chinese medicine preparation for the treatment of aplastic anemia, is used for the treatment for the treatment of aplastic anemia disease, belongs to traditional Chinese medical science pharmaceutical technology field.

background technology;

Treatment aplastic anemia, if adopt for a long time Western medicine and treatment of blood transfusion, will produce very large damage to Liver and kidney and skeleton at present.Such as, with hormone, its side effect is very large, and human body is got fat, skeletal injury.Long-term periodic transfusions, can produce sidcrosis.Long-term transfusion platelet will produce platelet antibody in body, causes final platelet transfusion no longer to play anastalsis.Using treatment by Chinese herbs aplastic anemia, make body recovery vigour, improve gradually bone marrow hematogenesis function, is that human body recovers life, reduces patient's misery, extending life.

summary of the invention;

The invention provides a kind of Chinese medicine preparation for the treatment of aplastic anemia, it is characterized in that being made by ratio of weight and the number of copies by following medicine:

Radix Ginseng Rubra 28-35, Radix Pseudostellariae 20-30, Rhizoma Atractylodis Macrocephalae (parched) 18-25, Colla Corii Asini 18-22, Poria 18-22, Radix Angelicae Sinensis 12-18, Rhizoma Chuanxiong 8-12, stir-fry Radix Rubiae 8-12, the Radix Paeoniae Alba 8-12, Radix Salviae Miltiorrhizae 8-12, the Radix Rehmanniae 8-12, Radix Curcumae 8-12, Fructus Mori 8-12, Radix Dipsaci 8-12, Pheretima 8-12, Rhizoma Corydalis 8-12, Fructus Citri Sarcodactylis 4-8, Fructus Schisandrae Chinensis 3-8.

Best proportioning;

Radix Ginseng Rubra 30, Radix Pseudostellariae 25, Rhizoma Atractylodis Macrocephalae (parched) 20, Colla Corii Asini 20, Poria 20, Radix Angelicae Sinensis 15, Rhizoma Chuanxiong 10, stir-fry Radix Rubiae 10, the Radix Paeoniae Alba 10, Radix Salviae Miltiorrhizae 10, the Radix Rehmanniae 10, Radix Curcumae 10, Fructus Mori 10, Radix Dipsaci 10, Pheretima 10, Rhizoma Corydalis 10, Fructus Citri Sarcodactylis 6, Fructus Schisandrae Chinensis 5.The Chinese medicine preparation for the treatment of aplastic anemia provided by the invention, preparation technology is as follows:

Take according to the above ratio each herbal medicine, remove impurity, being decocted in water for oral dose of 3 ~ 5 times of doses, fried 3 times, each 60 ~ 120 minutes fried completing, collecting decoction and get final product.

The present invention also can take each herbal medicine according to the above ratio, removes impurity, is ground into 80 ~ 150 order fine powders, packs hard capsules into, makes capsule preparations. usage and consumption;each 40 ~ 50 milliliters; Every day 2 times; 90 days course for the treatment of.

indication;aplastic anemia, thrombocytopenic purpura.

side separates;radix Ginseng Rubra, Radix Pseudostellariae, Rhizoma Atractylodis Macrocephalae (parched) are supported unit for air making-up and spleen enlivening, are monarch drug; Assistant is with Colla Corii Asini, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Poria benefiting qi and nourishing blood dampness removing; Fructus Mori, Radix Dipsaci, Pheretima Bushen Tongluo; Fry Radix Rubiae, Radix Curcumae, the Radix Rehmanniae, the cooling blood for hemostasis of Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling; Fructus Citri Sarcodactylis, Rhizoma Corydalis, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis is soothing the liver circulation of qi promoting convergence. below in conjunction with clinical, further illustrate good effect of the present invention:

diagnostic criteria:

1. pancytopenia, network address erythrocyte absolute value lowers;

2. generally without hepatosplenomegaly;

3. bone marrow examination shows that at least one part hypoplasia or severe lower (if active proliferation must have Megakaryocytic minimizing, charcoal nucleated red blood cell increases, and in bone marrow granule composition, should see that non-hematopoietic cell increases);

4. except energy, other causes the disease of cytopenia.As paroxysmal nocturnal hemoglobinuria, leukemia, malignant histocytosis etc.

treatment standard;

1. substantially cure; Anemia, bleeding disappears, and hemoglobin reaches the above leukocyte 4.0x10 of male 120g/l, female 100g/l ⁹/ l; More than platelet reaches 8.0 ten thousand/l, follow up a case by regular visits to above nothing recurrence in a year.2. effective; Anemia, bleeding disappears, and hemoglobin reaches male 120g/l, female 100g/l, leukocyte 3.5x10 ⁹/ l left and right, platelet also has degree to recover, and follows up a case by regular visits to three months stable disease or continues progress person.3. effective; Anemia, bleeding is clearly better, and does not transfuse blood, and hemoglobin is treated in first 1 month more than modal value increases 30g/l, and maintains 3 months and do not decline.4; Invalid; After fully treating, symptom hemogram can not reach obvious progressive person.Curative effect proves;

For showing the therapeutic effect of medicine of the present invention, the patient of selected following 100 routine aplastic anemia diseases, takes medicine of the present invention and treats, and through clinical observation, analyzes and is summarized as follows: cure: 60%; Effective: 20%; Effective: 15%; Invalid: 5%.

good effect of the present invention is;adopting treatment by Chinese herbs aplastic anemia, is with pure Chinese medicinal preparation, and drug effect is rapid, and clinical symptom disappearance is fast, and toxic and side effects is little, short treating period, and painful little, expense is low.

The specific embodiment

embodiment 1

Take 30 grams of Radix Ginseng Rubra, 25 grams of Radix Pseudostellariaes, 20 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 20 grams of Porias, 20 grams, Colla Corii Asini, 15 grams of Radix Angelicae Sinensis, 10 grams of Rhizoma Chuanxiongs, fry 10 grams, Radix Rubiae, 10 grams of the Radix Paeoniae Albas, 10 grams of Radix Salviae Miltiorrhizaes, 10 grams, the Radix Rehmanniae, 10 grams of Radix Curcumaes, 10 grams of Fructus Mori, 10 grams of Radix Dipsaci, 10 grams of Pheretimas, 10 grams of Rhizoma Corydalis, 6 grams of Fructus Citri Sarcodactylis, 5 grams of Fructus Schisandrae Chinensis, remove impurity, being decocted in water for oral dose of 3 ~ 5 times of doses, fried 3 times, each 60 ~ 120 minutes fried completing, collecting decoction and get final product.

embodiment 2

Take Radix Ginseng Rubra 28g, Radix Pseudostellariae 20g, Rhizoma Atractylodis Macrocephalae (parched) 18g, Colla Corii Asini 18g, Poria 18g, Radix Angelicae Sinensis 12g, Rhizoma Chuanxiong 8g, fry Radix Rubiae 8g, Radix Paeoniae Alba 8g, Radix Salviae Miltiorrhizae 8g, Radix Rehmanniae 8g, Radix Curcumae 8g, Fructus Mori 8g, Radix Dipsaci 8g, Pheretima 8g, Rhizoma Corydalis 8g, Fructus Citri Sarcodactylis 4g, Fructus Schisandrae Chinensis 3g, remove impurity, being decocted in water for oral dose of 3 ~ 5 times of doses, fried 3 times, each 60 ~ 120 minutes fried completing, collecting decoction and get final product.

embodiment 3

Take Radix Ginseng Rubra 35g, Radix Pseudostellariae 30g, Rhizoma Atractylodis Macrocephalae (parched) 25g, Colla Corii Asini 22g, Poria 22g, Radix Angelicae Sinensis 18g, Rhizoma Chuanxiong 12g, fry Radix Rubiae 12g, Radix Paeoniae Alba 12g, Radix Salviae Miltiorrhizae 12g, Radix Rehmanniae 12g, Radix Curcumae 12g, Fructus Mori 12g, Radix Dipsaci 12g, Pheretima 12g, Rhizoma Corydalis 12g, Fructus Citri Sarcodactylis 8g, Fructus Schisandrae Chinensis 8g, remove impurity, being decocted in water for oral dose of 3 ~ 5 times of doses, fried 3 times, each 60 ~ 120 minutes fried completing, collecting decoction and get final product.

selected following case further illustrates curative effect of the present invention:

Case 1

Ni XX, female, 44 years old; With chronic aplastic anemia, go to a doctor, by Drug therapy of the present invention, 40 milliliters of each administrations, twice of every day.The chronotherapy state of an illness about 12 months is clearly better, and hemogram reaches normally (for details see attached table 1) substantially.Not bounce-back.

Case 2

Field XX, female, 20 years old; With chronic aplastic anemia, go to a doctor.By Drug therapy of the present invention, 35 milliliters of each administrations, twice of every day.After 8 months, complete blood cell all obviously rises, and has the treatment hemogram through 6 months to recover normal level, and complete blood cell numerical value is normal (for details see attached table 1) all.Without bounce-back.

Case 3

Health XX, man, 65 years old; With chronic aplastic anemia, go to a doctor.By Drug therapy of the present invention, twice of each administration 55 milliliters of every day.After medication in 13 months treatment, complete blood cell all to some extent obviously rises, and the original ill symptoms of patient disappears substantially.Depletion of blood deficient syndrome shape.Continue medication after 2 months, complete blood cell numerical value is normal (for details see attached table 1) all.Discontinue medication, without bounce-back.

Table 1

Claims

1. treat a Chinese medicine preparation for aplastic anemia, it is characterized in that being made by ratio of weight and the number of copies by following medicine:

2. a kind of Chinese medicine preparation for the treatment of aplastic anemia according to claim 1, it is characterized in that being made by ratio of weight and the number of copies by following medicine:

Radix Ginseng Rubra 30, Radix Pseudostellariae 25, Rhizoma Atractylodis Macrocephalae (parched) 20, Colla Corii Asini 20, Poria 20, Radix Angelicae Sinensis 15, Rhizoma Chuanxiong 10, stir-fry Radix Rubiae 10, the Radix Paeoniae Alba 10, Radix Salviae Miltiorrhizae 10, the Radix Rehmanniae 10, Radix Curcumae 10, Fructus Mori 10, Radix Dipsaci 10, Pheretima 10, Rhizoma Corydalis 10, Fructus Citri Sarcodactylis 6, Fructus Schisandrae Chinensis 5.

3. according to treating a kind of preparation method for the treatment of the Chinese medicine preparation of aplastic anemia described in claim 1 or 2, concrete steps are as follows: take according to the above ratio each herbal medicine, remove impurity, being decocted in water for oral dose of 3 ~ 5 times of doses, fried 3 times, each 60 ~ 120 minutes fried completing, collecting decoction and get final product.