CN103249402A - 新组合物 - Google Patents

新组合物 Download PDF

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Publication number
CN103249402A
CN103249402A CN2011800593868A CN201180059386A CN103249402A CN 103249402 A CN103249402 A CN 103249402A CN 2011800593868 A CN2011800593868 A CN 2011800593868A CN 201180059386 A CN201180059386 A CN 201180059386A CN 103249402 A CN103249402 A CN 103249402A
Authority
CN
China
Prior art keywords
composition
phenoxy
quinoline
methyl
pyrrolo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2011800593868A
Other languages
English (en)
Chinese (zh)
Inventor
胡彦民
安东尼·R·科茨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Helperby Therapeutics Ltd
Original Assignee
Helperby Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1016999.3A external-priority patent/GB201016999D0/en
Priority claimed from GBGB1107756.7A external-priority patent/GB201107756D0/en
Application filed by Helperby Therapeutics Ltd filed Critical Helperby Therapeutics Ltd
Publication of CN103249402A publication Critical patent/CN103249402A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN2011800593868A 2010-10-08 2011-10-07 新组合物 Pending CN103249402A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1016999.3 2010-10-08
GBGB1016999.3A GB201016999D0 (en) 2010-10-08 2010-10-08 Novel composition
GB1107756.7 2011-05-10
GBGB1107756.7A GB201107756D0 (en) 2011-05-10 2011-05-10 Novel composition
PCT/GB2011/051931 WO2012046078A1 (en) 2010-10-08 2011-10-07 Novel composition

Publications (1)

Publication Number Publication Date
CN103249402A true CN103249402A (zh) 2013-08-14

Family

ID=44872428

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2011800593868A Pending CN103249402A (zh) 2010-10-08 2011-10-07 新组合物

Country Status (6)

Country Link
US (1) US20130245060A1 (cg-RX-API-DMAC7.html)
EP (1) EP2624817A1 (cg-RX-API-DMAC7.html)
JP (1) JP2013538868A (cg-RX-API-DMAC7.html)
CN (1) CN103249402A (cg-RX-API-DMAC7.html)
CA (1) CA2811568A1 (cg-RX-API-DMAC7.html)
WO (1) WO2012046078A1 (cg-RX-API-DMAC7.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201107755D0 (en) * 2011-05-10 2011-06-22 Helperby Therapeutics Ltd Novel compounds

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007054693A1 (en) * 2005-11-08 2007-05-18 Helperby Therapeutics Limited Use of pyrroloquinoline compounds to kill clinically latent microorganisms
WO2008056151A1 (en) * 2006-11-08 2008-05-15 Helperby Therapeutics Limited Topical formulations

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1057131A (en) * 1963-02-21 1967-02-01 Boots Pure Drug Co Ltd New antibacterial and antifungal compositions
AU692486B2 (en) 1993-10-22 1998-06-11 Smithkline Beecham Corporation Pharmaceutical or veterinary composition comprising mupirocin or a salt thereof in a cream base
ZA954599B (en) * 1994-06-07 1996-01-26 Allergan Inc Stable gel formulation for topical treatment of skin conditions
GB9620985D0 (en) * 1996-10-08 1996-11-27 Gillette Co Ball point pen
KR20000076105A (ko) * 1998-01-13 2000-12-26 도리이 신이찌로 항생제를 함유한 국소 투여용 항균 조성물
WO2003011261A1 (en) 2001-08-01 2003-02-13 Medlogic Global Limited Cyanoacrylate monomer-containing antibiotic formulation for topical use
JP2007502861A (ja) * 2003-05-01 2007-02-15 レプリダイン・インコーポレーテッド 抗菌方法及び組成物
JP5460947B2 (ja) * 2003-09-03 2014-04-02 グラクソ グループ リミテッド 新規調製方法、塩、組成物及び使用
US20050058673A1 (en) * 2003-09-09 2005-03-17 3M Innovative Properties Company Antimicrobial compositions and methods
KR20070091613A (ko) 2004-11-08 2007-09-11 그렌마크 파머수티칼스 엘티디. 항여드름 화합물 및 항생제 화합물을 함유하는 국소적 제약조성물
WO2008106228A2 (en) * 2007-02-28 2008-09-04 Aciex Therapeutics, Inc. Methods and compositions for normalizing meibomian gland secretions
CA2790827A1 (en) * 2010-03-01 2011-09-09 Photocure Asa Cosmetic compositions
DK2600869T3 (da) * 2010-08-05 2020-11-16 Helperby Therapeutics Ltd Kombination af en pyrroloquinolinforbindelse og et beta-lactam-antimikrobielt middel, mupirocin eller chlorhexidin

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007054693A1 (en) * 2005-11-08 2007-05-18 Helperby Therapeutics Limited Use of pyrroloquinoline compounds to kill clinically latent microorganisms
WO2008056151A1 (en) * 2006-11-08 2008-05-15 Helperby Therapeutics Limited Topical formulations

Also Published As

Publication number Publication date
CA2811568A1 (en) 2012-04-12
WO2012046078A1 (en) 2012-04-12
EP2624817A1 (en) 2013-08-14
US20130245060A1 (en) 2013-09-19
JP2013538868A (ja) 2013-10-17

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20130814