CN103239588B - Chinese medicine composite for treating cervical spondylosis - Google Patents

Abstract

The invention provides a Chinese medicine composition for treating cervical spondylosis, aiming at solving the problem that the existing Chinese medicine for treating cervical spondylosis is unstable in curative effect. The Chinese medicine composition is prepared from milkvetch, codonopsis pilosula, peach kernel, the root of kudzu vine, safflower, sichuan lovage rhizome, Chinese angelica, root of rehmannia, white peony root, rhizoma cyperi, earthworm, manis pentadactyla, ground beeltle, radix clematidis and gentiana macrophylla. The milkvetch and the codonopsis pilosula are used for tonifying qi; the safflower, the Sichuan lovage rhizome, the Chinese angelica, the white peony root and the peach kernel are used for promoting blood circulation to remove meridian obstruction, breaking blood stasis and promoting coronary circulation; the ground beeltle, the manis pentadactyla, the earthworm and the rhizoma cyperi are used for regulating vital energy in blood and stopping pain; the radix clematidis, the bark of ash and the chingma abutilon seed are added for dispelling rheumatism, benefiting joints and smoothening energy channels; and the root of kudzu vine is added for relieving stiffness of cervical vertebra and neck pain. The Chinese medicine composition for treating cervical spondylosis is applicable to cervical spondylosis caused by different causes and has the advantages of quick effect, short treatment course, high curative ratio and stable curative effect.

Description

A kind of Chinese medicine composition for the treatment of cervical spondylosis

Technical field

The present invention relates to a kind of medicine for the treatment of cervical spondylosis, relate in particular to a kind of Chinese medicine composition for the treatment of cervical spondylosis.

Background technology

Cervical spondylosis claims again cervical vertebra syndrome, is the general name due to degeneration of cervical intervertebral disc, the caused spinal osteoarthritis of hyperosteogeny of cervical vertebra, proliferative cervical spondylosis, cervical syndrome, Cervical disc extrusion.Cervical spondylosis can be divided into neck type, spondylotic radiculopathy, myeloid form, vertebral artery type, adrenergic type and its alloytype, the clinical back of the body and anterior pectorial region pain on neck, shoulder arm, omoplate, arm numbness of hand wood, amyotrophy, the even quadriplegia of often showing as.Can betide any age, take 40 years old above middle-aged and elderly people as many.Thicken and cause cervical vertebra spinal cord, nerve root or vertebral artery pressurized to occur a series of handicapped clinical syndromes mainly due to cervical vertebra strain for a long time, hyperosteogeny, prolapse of intervertebral disc, ligament.Doctor trained in Western medicine adopts operating method to treat; Due to this sick cause of disease complexity, after western medical treatment, there is easy feature repeatedly.

Chinese medicine is attributed to cervical spondylosis categories such as " arthromyodynia, dizzy, the diseases of withering ", how to prove from aspects such as internal organs, QI and blood, deficiency and excess, the six channels; But, do not have at present unified typing standard.Due to the clinical manifestation difference of cervical spondylosis, cause the situation of one of the each one-tenth of Chinese medical discrimination, and there is repeatable poor, the unsettled problem of curative effect in the Chinese medicine of clinical use.

Summary of the invention

The unsettled problem of curative effect existing in order to solve the Chinese medicine of existing treatment cervical spondylosis; The invention provides a kind of Chinese medicine composition for the treatment of cervical spondylosis.The Chinese medicine composition for the treatment of cervical spondylosis of the present invention is applicable to the cervical spondylosis that various different pathogenies cause, and stable curative effect.

Technical scheme of the present invention:

1. treat a Chinese medicine composition for cervical spondylosis, formed by the raw material of Chinese medicine of following weight parts:

30 parts of the Radixs Astragali, 15 parts of Radix Codonopsis, 10 parts, Semen Persicae, 15 parts of Radix Puerariaes, 10 parts, Flos Carthami, 20 parts of Rhizoma Chuanxiongs, 15 parts of Radix Angelicae Sinensis, 10 parts, the Radix Rehmanniae, 10 parts of the Radix Paeoniae Albas, 10 parts of Rhizoma Cyperis, 10 parts of Pheretimas, 10 parts of Squama Maniss, 10 parts of Eupolyphaga Seu Steleophagas, 15 parts of Radix Clematidis, 15 parts of Radix Gentianae Macrophyllae.

2. treat a Chinese medicine composition for cervical spondylosis, formed by the raw material of Chinese medicine of following weight parts:

30 parts of the Radixs Astragali, 15 parts of Radix Codonopsis, 10 parts, Semen Persicae, 15 parts of Radix Puerariaes, 10 parts, Flos Carthami, 20 parts of Rhizoma Chuanxiongs, 15 parts of Radix Angelicae Sinensis, 10 parts, the Radix Rehmanniae, 10 parts of the Radix Paeoniae Albas, 10 parts of Rhizoma Cyperis, 10 parts of Pheretimas, 10 parts of Squama Maniss, 10 parts of Eupolyphaga Seu Steleophagas, 15 parts of Radix Clematidis, 15 parts of Radix Gentianae Macrophyllae, 10 parts of Semen Abutili.

The present invention's each raw material of Chinese medicine used is dry product, and its property of medicine is as follows:

The Radix Astragali, sweet in the mouth, slightly warm in nature, return liver, spleen, lung, kidney channel, has effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema;

Radix Codonopsis, property is flat, sweet in the mouth, enters spleen, lung meridian, invigorating the spleen and replenishing QI;

Semen Persicae, property is flat, bitter in the mouth, sweet, GUIXIN, liver, large intestine channel, blood stasis removing and clots absorbing;

Radix Puerariae, cool in nature, sweet in the mouth, pungent, returns spleen, stomach warp, and expelling pathogenic factors from muscles for reducing heat, for outer stiff nape and back, neck pain; Flos Carthami, warm in nature, acrid in the mouth, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.

Rhizoma Chuanxiong, warm in nature, acrid in the mouth, returns liver, gallbladder, pericardium channel, blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping;

Radix Angelicae Sinensis, warm in nature, sweet in the mouth, pungent, returns liver, the heart, spleen channel, enriches blood, pain relieving;

The Radix Rehmanniae, cold in nature, sweet in the mouth, hardship, GUIXIN, liver, kidney channel, clearing away heat and cooling blood;

The Radix Paeoniae Alba, cold nature, bitter in the mouth, acid, sweet, return liver, spleen channel, nourishing blood to suppress the hyperactive liver, slow middle pain relieving;

Rhizoma Cyperi, property is flat, acrid in the mouth, micro-hardship, micro-sweet, returns liver, spleen, tri-jiao channel, promoting QI circulation for relieving depression, pain relieving;

Pheretima, cold in nature, salty in the mouth, returns liver, spleen, urinary bladder channel, clearing heat for calming endogenous wind, dredging collateral;

Squama Manis, cold nature, salty in the mouth, return liver, stomach warp, blood circulation promoting and dispersing pathogen accumulation;

Eupolyphaga Seu Steleophaga, cold in nature, salty in the mouth, returns Liver Channel, mild toxicity, removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones;

Radix Clematidis, warm in nature, acrid in the mouth, salty, returns urinary bladder channel, expelling wind and removing dampness, removing obstruction in the collateral to relieve pain;

Radix Gentianae Macrophyllae, property is flat, acrid in the mouth, hardship, returns stomach, liver, gallbladder meridian, stopping numbness pain Eradicates rheumatism, relaxing muscles and tendons network;

Semen Abutili, property is flat, bitter in the mouth, returns large intestine, small intestinal, urinary bladder channel, clearing away heat-damp and promoting diuresis, removing toxic substances.

The Chinese medicine composition for the treatment of cervical spondylosis of the present invention, by the Radix Astragali, Radix Codonopsis QI invigorating; Flos Carthami, Rhizoma Chuanxiong, Radix Angelicae Sinensis, the Radix Paeoniae Alba and Semen Persicae promoting blood circulation to remove obstruction in the collateral, and promote blood circulation it with removing blood stasis with potent drugs blood; Gas in Eupolyphaga Seu Steleophaga, Squama Manis, Pheretima and Rhizoma Cyperi treating blood disorders and relieving the pain; Add Radix Clematidis, Radix Gentianae Macrophyllae, the loose rheumatism of Semen Abutili, sharp joint, the meridian dredging; Add Radix Puerariae to alleviate cervical vertebra stiffness, neck pain.

Chinese medicine composition of the present invention is prepared into decoction, electuary, ball (watered pill, honeyed pill etc.), powder, unguentum, injection by conventional preparation method.

The consumption of the Chinese medicine composition for the treatment of cervical spondylosis of the present invention: calculate with medicinal raw material, medication every day 100-215g, takes at twice, sooner or later respectively once.

Beneficial effect of the present invention:

1. instant effect, short treating period, cure rate are high;

2. the scope of application is wide, and various types of cervical spondylosiss are all had to remarkable result.

The test of pesticide effectiveness

For showing the treatment therapeutic effect of the present invention to cervical spondylosis, choose 200 examples (spondylotic radiculopathy 92 examples through system clinical observation, vertebral artery type 60 examples, myeloid form 16 examples, sympathetic type 12 examples, mixed type 20 examples) Patients with Cervical Spondylopathy, 200 routine patients are equally divided into four groups, four groups of patients are learning processing by statistics aspect sex, age, the state of an illness and the course of disease, no significant difference, has comparability; Wherein three groups is test group, and one group is matched group.Enter group standard: 1) course of disease is between 10 days to 5 years, without obvious wound; 2) all there is stiff neck history repeatedly, neck and shoulder part, nape portion or Jingbi portion discomfort, the symptoms such as pain and cervical region moving obstacle; 3) I or family members' informed consent.

Patient's symptom:

1 cervical spondylotic radiculopathy, corresponding nerve root domination district's reflexive pain or radiated pain, paraesthesia, muscular strength change and reflection changes; Neck hyperextension, cough, sneeze can make pain increase the weight of; Point dumb, fine movement difficulty; Check visible ill side neck and shoulder part muscular tone, restriction of neck motion, spinal column tenderness, suffering limb can be felt, and obstacle, muscular strength weaken, amyotrophy; Brachial plexus distraction test, the intervertebral foramina compression test positive.

2 cervical spondylotic myelopathies, in early days for one-sided or bilateral weakness of the lower extremities, numb, later instability of gait, difficulty in walking, can have trunk and upper limb numbness sense; Muscle tension of lower extremities increases, tendon hyperreflexia is more common; Severe patient has fecal and urinary functions obstacle.

3 sympathetic type of cervical spondylosis, 1. incidence symptom: cervicodynia, headache, dizzy etc.; .2. eye symptom: eye distending pain, blurred vision, platycoria or dwindle, severe one can be blind; 3. heart sympton: precordialgia, tachycardia or bradycardia; 4. other symptom: limbs or head pain or numbness, limbs feel cold or limbs flushing, tinnitus or auditory dysesthesia etc.

4 vertebral artery type of cervical spondylosiss, 1. headache, generally or head one side rear in pillow; 2. balance and internal ear symptom: have dizzy, tinnitus, auditory dysesthesia etc.; 3. visual deterioration or diplopia, severe one is even blind; 4. other: memory and intelligence decline, dysphonia, minority can be dampinged off.

5 Mixed Cervical Spondylosis, have above-mentioned two or more pathological change and clinical manifestation persons concurrently.

Treatment measure

Test group 1: take decoction prepared by embodiments of the invention 1; Calculate with raw material of Chinese medicine, medication every day 205g, takes at twice, sooner or later respectively once;

Test group 2: take powder prepared by embodiments of the invention 2; Calculate with raw material of Chinese medicine, medication every day 100g, divides and takes for 2 times, sooner or later respectively once;

Test group 3: take decoction prepared by embodiments of the invention 3; Calculate with raw material of Chinese medicine, medication every day 215g, divides 2 to take, sooner or later respectively once;

Matched group: take following Chinese medicine decoction: 15 grams of Radix Angelicae Pubescentiss, 15 grams of Herba Taxillis, 10 grams of Radix Gentianae Macrophyllae, 15 grams of Radix Saposhnikoviaes, 3 grams of Herba Asaris, 15 grams of Radix Angelicae Sinensis, 12 grams of the Radix Paeoniae Albas, 15 grams of Rhizoma Chuanxiongs, 15 grams of Radix Rehmanniae, 12 grams of the Cortexs Eucommiae, 15 grams of Radix Achyranthis Bidentataes, 20 grams of Radix Codonopsis, 12 grams, Poria, 10 grams of Radix Glycyrrhizae Preparatas, 15 grams of Ramulus Cinnamomi; One consumption per day, is decocted in water for oral dose, and divides 2 to take, sooner or later respectively once.

Criterion of therapeutical effect

Excellent: subjective symptoms disappears, and cervical region activity is unrestricted, resumes work;

Good: conscious most of transference cure, but after tired, neck and shoulder part is slightly ached;

Effective: symptom and sign part take a turn for the better, but often have shoulder brachialgia, can recover light work;

Invalid: symptom and sign have no improvement.

Through the treatment of 3 months, respectively the therapeutic effect of test group and matched group to be added up, result is as table 1;

Table 1

。In the final patient who cures of test group, patient takes effect after the shortest 5 days taking medicine of the present invention, and subjective symptoms disappearance after the shortest 13 days, cervical region activity be unrestricted, resume work; More than 90% patient takes effect taking medicine of the present invention for 12 days, takes that subjective symptoms after 30-60 days disappears, cervical region activity is unrestricted, resumes work; Total effective rate is 96%, and total cure rate is 93.3%.

In the final patient who cures of test group, patient takes effect after the shortest 7 days at drug administration, and subjective symptoms disappearance after the shortest 21 days, cervical region activity be unrestricted, resume work; More than 90% patient takes effect taking medicine of the present invention for 18 days; Take that subjective symptoms after 60-90 days disappears, cervical region activity is unrestricted, resume work; Total effective rate is 76%, and total cure rate is 54%.Therefore there is instant effect, short treating period, advantage that cure rate is high in medicine of the present invention.

The patient that test group 150 example is dissimilar, the therapeutic effect in the time of medication 60 days is as table 2,

Table 2

?	Test group 1	Test group 2	Test group 3
				Spondylotic radiculopathy 23 examples	Invalid: 1 example	Invalid: 2 examples	Invalid: 1 example
Vertebral artery type 15 examples	Invalid: 1 example	Invalid: 1 example	Invalid: 0 example
				Myeloid form 4 examples	Invalid: 0 example	Invalid: 0 example	Invalid: 0 example
Sympathetic type 3 examples	Invalid: 0 example	Invalid: 0 example	Invalid: 0 example
				Mixed type 5 examples	Invalid: 0 example	Invalid: 0 example	Invalid: 0 example

Illustrate that medicine of the present invention all has good efficacy to various types of cervical spondylosiss, possesses extensive, stable therapeutic effect.

Model case

Lee, man, 56 years old, check its side neck and shoulder part muscular tone, restriction of neck motion, spinal column tenderness, suffering limb can be felt, and obstacle, muscular strength weaken, amyotrophy, brachial plexus distraction test, the intervertebral foramina compression test positive; Be diagnosed as cervical spondylotic radiculopathy; The course of disease 3 years; Adopt the medicine of embodiment 1 to treat.Medication took effect after 7 days; After medication 32 days, subjective symptoms disappears, and cervical region activity is unrestricted, resumes work.In 3 years, follow the tracks of and pay a return visit, not recurrence.

Wang, female 36 years old, bilateral weakness of the lower extremities, numb, later instability of gait, difficulty in walking, limb muscular hypertonia, tendon hyperreflexia also have headache, dizzy symptom simultaneously; Be diagnosed as the Mixed Cervical Spondylosis of myeloid form and sympathetic type; The course of disease 2 years; Adopt the medicine of embodiment 3 to treat.Medication took effect after 12 days; After medication 63 days, subjective symptoms disappears, and cervical region activity is unrestricted, resumes work.In 3 years, follow the tracks of and pay a return visit, not recurrence.

The specific embodiment

Embodiment 1

Get Radix Astragali 30g, Radix Codonopsis 15g, Semen Persicae 10g, Radix Puerariae 15g, Flos Carthami 10g, Rhizoma Chuanxiong 20g, Radix Angelicae Sinensis 15g, Radix Rehmanniae 10g, Radix Paeoniae Alba 10g, Rhizoma Cyperi 10g, Pheretima 10g, Squama Manis 10g, Eupolyphaga Seu Steleophaga 10g, Radix Clematidis 15g, Radix Gentianae Macrophyllae 15g; Decoct with water 2.5h; Filter, filtrate is concentrated into 400ml.

Embodiment 2

Get Radix Astragali 30g, Radix Codonopsis 15g, Semen Persicae 10g, Radix Puerariae 15g, Flos Carthami 10g, Rhizoma Chuanxiong 20g, Radix Angelicae Sinensis 15g, Radix Rehmanniae 10g, Radix Paeoniae Alba 10g, Rhizoma Cyperi 10g, Pheretima 10g, Squama Manis 10g, Eupolyphaga Seu Steleophaga 10g, Radix Clematidis 15g, Radix Gentianae Macrophyllae 15g; Be ground to 400 orders and obtain powder.

Embodiment 3

Get Radix Astragali 30g, Radix Codonopsis 15g, Semen Persicae 10g, Radix Puerariae 15g, Flos Carthami 10g, Rhizoma Chuanxiong 20g, Radix Angelicae Sinensis 15g, Radix Rehmanniae 10g, Radix Paeoniae Alba 10g, Rhizoma Cyperi 10g, Pheretima 10g, Squama Manis 10g, Eupolyphaga Seu Steleophaga 10g, Radix Clematidis 15g, Radix Gentianae Macrophyllae 15g, Semen Abutili 10g; Decoct with water 2.5h; Filter, filtrate is concentrated into 400ml.

Claims (2)

1. a Chinese medicine composition for the treatment of cervical spondylosis, is characterized in that, is made up of the raw material of Chinese medicine of following weight parts:

30 parts of the Radixs Astragali, 15 parts of Radix Codonopsis, 10 parts, Semen Persicae, 15 parts of Radix Puerariaes, 10 parts, Flos Carthami, 20 parts of Rhizoma Chuanxiongs, 15 parts of Radix Angelicae Sinensis, 10 parts, the Radix Rehmanniae, 10 parts of the Radix Paeoniae Albas, 10 parts of Rhizoma Cyperis, 10 parts of Pheretimas, 10 parts of Squama Maniss, 10 parts of Eupolyphaga Seu Steleophagas, 15 parts of Radix Clematidis, 15 parts of Radix Gentianae Macrophyllae.

2. a Chinese medicine composition for the treatment of cervical spondylosis, is characterized in that, is made up of the raw material of Chinese medicine of following weight parts:

30 parts of the Radixs Astragali, 15 parts of Radix Codonopsis, 10 parts, Semen Persicae, 15 parts of Radix Puerariaes, 10 parts, Flos Carthami, 20 parts of Rhizoma Chuanxiongs, 15 parts of Radix Angelicae Sinensis, 10 parts, the Radix Rehmanniae, 10 parts of the Radix Paeoniae Albas, 10 parts of Rhizoma Cyperis, 10 parts of Pheretimas, 10 parts of Squama Maniss, 10 parts of Eupolyphaga Seu Steleophagas, 15 parts of Radix Clematidis, 15 parts of Radix Gentianae Macrophyllae, 10 parts of Semen Abutili.