CN103238898A - Life-prolonging drink with superior element spectrum and vitamin group - Google Patents

Abstract

The invention discloses a life-prolonging drink with a superior element spectrum and a vitamin group. The drink comprises a macro or trace element group, the superior element spectrum, the vitamin group, a free radical scavenging agent, bee series products, traditional Chinese medicine fluid extracts and water. According to the drink, on the basis of inheriting a precious life-prolonging prescription of the motherland, in combination with the modern trace element and vitamin medical essence, the balance of nutrient elements in a human body is kept, the special remarkable characteristic elements such as iron, manganese, zinc, strontium, chromium, selenium and the like required in a long-life crowd are fully supplemented, the free radicals in the human body are powerfully scavenged, the nutrient elements in the bee series products and the life-prolonging traditional Chinese medicine fluid extracts are comprehensively supplemented, the body is built to delay ageing by utilizing the theory of the balance of modern elements, vitamins and scientific nutrient elements, fluorine is supplemented to remove aluminum, copper is supplemented to remove cadmium, selenium is supplemented to remove lead, germanium is supplanted to add oxygen, and the purposes of preventing and treating diseases, protecting health and prolonging life are achieved by taking the superior trace elements and the vitamins for preparing the drink.

Description

The superior element spectral group vitamins beverage of life-saving

Technical field:

The present invention relates to a kind of superior element spectral group vitamins beverage of life-saving, is preparation and the technical field of producing that belongs to a kind of full nutritive element new beverage.

Background technology:

Vitamin and mineral matter are indispensable element in our life, their great majority can not synthesize in vivo, and must from meals, absorb, the main effect of its mineral is the formation of participant soma, keep osmotic pressure, keep the human acid-base balance, keep excitability neural and muscle, participate in constituting bone to support our health, keep the blood circulation of beating to promote us of heart rule, generate urine, to get rid of toxin and to keep alkalescent physique ... these functions all must have several mineral materials to participate in just finishing.And vitamin mainly is to participate in the activity of enzyme as coenzyme or with the form of prothetic group, keep and enormous function is arranged aspect the cell normal function regulating metabolism, and the disease that is deficient in vitamin and can produces, just too many, the C that for example is deficient in vitamin gets scurvy; The K that is deficient in vitamin can cause serious hemorrhage, and in fact each vitamin has many functions, just is example with the vitamin C.The vitamin C function reaches kind more than 300 according to the study, therefore be called as " mother of nutrient ", when hypovitaminosis C, other nutrient just is difficult to fully be absorbed and utilize, in fact, the effect of interdependence is arranged between vitamin and the mineral matter, mutually promoting, there are some researches show, when a kind of vitamin or mineral deficiency, just having hundreds of kind enzyme can not play a role normally, what therefore we can exaggerate not says, as long as a kind of obvious shortage consequence of nutrient will be very serious, or even fatal.

And the discovery of vitamin and mineral matter is human nutriology's a major contribution, has played important function to safeguarding human health.World Health Organization's report points out that human common disease has 135 kinds, and wherein 106 kinds of diseases are not enough relevant with the vitamin picked-up.If be deficient in vitamin in the human body, or vitamin intake imbalance, other vitamins just can not be absorbed smoothly, utilize by human body, thereby cause multiple disease, and are serious even can cause death.We can say there is not vitamin, human various vital movements can not go on.And replenishing vitamins is the most international fashion health idea.

Vitamin and mineral matter are the indispensable nutrients of human body.Common supporting one's family have fat-soluble (comprising vitamin A, D, E and K) and water miscible (comprising vitamin B1, B2, B6, B12 and C, pantothenic acid, folic acid, nicotinic acid, choline and biotin).Mineral matter is divided into macroelement (comprising calcium, phosphorus, potassium, sodium and magnesium) and trace element again.Essential trace element comprises 15 kinds of iron, zinc, selenium, iodine, copper, manganese, chromium, fluorine, molybdenum, cobalt, nickel, tin, silicon, vanadium, germanium.

Summary of the invention:

The object of the present invention is to provide a kind of superior element spectral group vitamins beverage of life-saving.

The scheme that the technology of the present invention solves is:

A kind of superior element spectral group vitamins beverage of life-saving is characterized in that: form % by following proportion by weight

(1) the Chinese medicine liquid extract is formed % by following traditional Chinese medicines prescription same amount proportion by weight

1. cultivated land, Ba Qiantian, the stem of noble dendrobium, saline cistanche, monkshood, the fruit of Chinese magnoliavine, Fructus Corni, Chinese cassia tree, the tuber of dwarf lilyturf, Poria cocos, calamus, polygala root;

2. glossy ganoderma, the fleece-flower root, the fruit of Chinese wolfberry, Poria cocos, Cordyceps sinensis, gynostemma pentaphylla, rhodiola root, the Radix Astragali, sealwort, the bark of eucommia, Radix Angelicae Sinensis, spina date seed, dandelion, pollen pini;

3. the fleece-flower root, the fruit of Cherokee rose, the fruit of glossy privet, the seed of Chinese dodder, mulberry fruit, Common St.Paulswort Herb, radix cyathulae;

4. RADIX POLYGONI MULTIFLORI PREPARATA, Poria cocos, saline cistanche, mulberry fruit, the seed of Chinese dodder, the fruit of Cherokee rose, fruit of glossy privet, Common St.Paulswort Herb, caulis lonicerae;

5. the dried rhizome of rehmannia, the tuber of dwarf lilyturf, the fruit of Chinese wolfberry, the bark of eucommia, raspberry, Chinese cassia tree, red ginseng;

6. prepared rhizome of rehmannia, saline cistanche, the fruit of Chinese magnoliavine, the seed of Chinese dodder, the seed of Oriental arborvitae, lucid asparagus, frutus cnidii, raspberry, bar halberd, the stem of noble dendrobium, teasel root, rhizoma alismatis, genseng, Chinese yam, polygala root, Fructus Corni, calamus, the osmanthus heart, PORIA ALBA, the bark of eucommia, day male, clock milk powder;

7. genseng, radix cyathulae, river Radix Angelicae Sinensis, the dried rhizome of rehmannia, cultivated land, the seed of Oriental arborvitae, the bark of eucommia, the fruit of Chinese wolfberry, the seed of Chinese dodder, grass-leaved sweetflag, the root bark of Chinese wolf-berry, Morinda officinalis;

(2) form % by following macro micro element proportion by weight

Macroelement

Trace element

More than each is grand, each component sum of trace element is 100%;

(3) the superior element spectral of strengthening long-lived crowd is formed (μ g/g) by following proportion by weight

Above beneficial element can only height can not be low, harmful element can only hang down can not be high;

(4) group vitamins, removing free radical material, the serial nutritious material of honeybee are formed % by following proportion by weight

1. group vitamins is formed % by following mass parts

Water soluble vitamin is by vitamin B1, B2, B6, B12 and C, and each same amount material of pantothenic acid, folic acid, nicotinic acid, choline and biotin is formed;

Liposoluble vitamin is made up of 95% vitamin E and 5% vitamin A, D, K;

2. the powerful material of removing free radical is formed % by following mass parts

Metallothionein, nanometer selenium, vitamin C, E, β-carrot equal in quality become to be grouped into;

3. honeybee series mixing nano powder is grouped into % by following bee product quality

Formed by each component same amount of honey, royal jelly, melissa powder, propolis, honeycomb, larva of bee, bee pupa, bee imago and pollen pini;

Rich selenium germanium glossy ganoderma mycelium xeraphium is to be obtained through vacuum freezedrying by organic selenium, organic germanium that the rich selenium of lucid ganoderma fungus, the microbial conversion of germanium resource are obtained.

Life-saving is human common aspiration.

The factor that influences human longevity is a lot.Inherent cause is the internal cause that determines human longevity, and external cause also affects the life-span.

The geographical environment of country variant, weather, economic level, folkways and customs, sanitary condition, cultural quality difference are also different to the influence in life-span.

Natural environment, dietetic nutrition, mental emotion, life style, disease, home environment, sex, occupation all affect the life-span.

The mankind have carried out unremitting exploration to the life-saving problem, have paid huge cost, have gained most valuable experience.

13 years " Yongtai county annals " 12 volume record: Chen Jun of the Qianrong of the Qing Dynasty, the word gram is bright, builds Tang Qun village, mountain area, Yongjia (Tang Cheng village, Chinese parasol tree township, modern Yongjia county) people, is born in the happy Tang Dynasty and hot ugly year (881 years Christian eras), die from the Yuan Dynasty and safe decide year in the cycle of sixty years (1324 Christian eras), 443 years old all the year round.

Li Qingyuan is born in 18 years (1679 Christian eras) of Kangxu clearly, die from the Republic of China 24 years (nineteen thirty-five in Christian era), 256 years old all the year round.There is the people that he is interviewed in the time of 250 years old, is organized into " readme " literary composition, reside in generation.

China five generations Du Guangting thinks: " life is in generation, but support proper, can be to 120 years old ... its longevity, multiple support proper can 240 years old, 480 years old, but do not hinder also.”

The far away supplement to Thousand Golden Prescriptions of the Tang Dynasty Sun Si is rolled up 12 " taboos of nourishing one's nature " and thought: " life day of one's doom a century, the joint person of protecting can be to Your Highness." Britain geneticist John Harris thinks, the breakthrough of gene research, the potentiality that might live 1200 years old.

Trace element can delay senility

The theory of relevant mankind aging's mechanism is a lot, summary is got up, heredity and non-genetic factor two classes are arranged, and wherein many link trace elements play an important role, and research at present concentrates on 10 kinds of trace elements such as zinc, manganese, copper, cadmium, iron, chromium, selenium, lead, aluminium and fluorine mostly.

1. replenishing zinc and manganese can delay senility

Aging slows down relevant with propagation and the differentiation of cell.The prerequisite of cell proliferation is the authenticity of dna replication dna, and DNA copies the catalysis that needs archaeal dna polymerase and just can finish.The differentiation of cell must RNA transcribe and synthetic protein just can be finished, and RNA must transcribe the catalysis that RNA polymerase must be arranged, more than two kinds of polymerizations the activation of zinc and manganese all must be arranged, just have higher catalytic.Therefore, the elderly will accelerate old and feeble process as lacking zinc and manganese deficiency, replenishes zinc and manganese in right amount, can delay senility.

Old and feeble relevant with the antioxidation attenuating, in antioxidation, superoxide dismutase (SOD) plays very important effect, it can change superoxides into the material of non-oxidation effect, thereby reach antioxidation, the participation of manganese must be arranged in the component of SOD, otherwise SOD does not just have activity, an amount of zinc and the manganese of replenishing can delay senility.

The elderly's hypothyroidism, hair bleaches, osteoporosis, hypophrenia, atherosclerotic, the sense of taste, sense of smell, vision go down, immunologic hypofunction etc., all relevant with scarce zinc and manganese deficiency, replenish zinc and manganese in right amount, can delay the generation of these the elderly's symptoms.

2. mending the copper bar cadmium can delay senility

Collagen is the maximum protein of people's in-vivo content, accounts for the 1/4-1/3 of human body protein total amount, is the key component of connective tissue, and collagenous fibres spread all over whole body everywhere, are not only the key component of loose connective tissue and tendon, also is the architecture basics of bone, tooth, cartilage.Copper is the activator of clostridiopetidase A, is the key factor of collagenic supersession, and when lacking copper, collagenic supersession takes place unusual easily, so easily cause loss of tooth, osteoporosis, fracture and muscular strain.When the elderly lacks copper, also can cause cytochrome oxidase and reduce, active decline, ataxia, staggered, thought slowness, the defeated obstacle of Railway transportation cause anaemia.

Cadmium is harmful trace element, behind the absorption cadmium, can cause little vascular smooth muscle and shrink or spasm, thereby hypertension takes place.Cadmium is excessive can to influence calcium metabolism, and the osteopathy as osteoporosis one class takes place.Therefore an amount of supplementation with copper of the elderly and discharge cadmium can delay senility.

3. replenishing iron and chromium can delay senility

The main cause that anaemia takes place the elderly is the ability reduction of red blood cell picked-up iron, and the utilization of iron reduces.Red blood cell picked-up iron, the normal person is 91.2%, normal the elderly then is 66%.Iron participates in the last oxidation stage of various cellular metabolisms and the generation of adenosine diphosphate (ADP), is the indispensable material of cellular metabolism.Immunity reduces during iron deficiency, and old man's appropriate supplement iron can improve immunity, reduces respiratory tract infection simultaneously.

Chromium is assisted insulin performance biologically active by forming GTF, and the sulfenyl that this factor can be regulated insulin and its acceptor on cell membrane (SH) forms disulfide bond and (S-S-), impels the maximum biological effect of insulin performance.The elderly lacks chromium and easily suffers from diabetes, and the elderly should replenish iron and chromium in right amount, can delay senility.

4. mending the selenium lead discharging can delay senility

Antioxidation is relatively poor and can not in time eliminate the major reason that free radical is the mankind aging, and this also is the molecular pathology basis of the elderly's frequently-occurring disease (as angiocardiopathy, the nervous system disease etc.).Selenium is the essential composition of glutathione peroxidase (GSH-Px), and GSH-Px is important antioxidase in the body, and it can poisonous oxide (ROOH) reduction of catalysis become nontoxic hydroxy compounds, thereby protects all biomembranes.

The elderly then removes the free radical effect and weakens as lacking selenium, and the active obviously decline of the Na-K-ATP enzyme on the cell membrane and 5 glycosides-nucleotidase, can cause Na, K, Ca ion discrepancy cellular abnormality and nucleotide metabolism disorder, causes serious consequence.When lacking selenium, myocardial freedom base content increases, and GSH-Px is active to be reduced, and myocardial contractility weakens, and this changes similar to old and feeble cardiac muscle.Selenium can stop lipid peroxide to combine with infringement cell membrane and deoxyribose nucleic acid macromolecular free radical roots such as (DNA) as antioxidant, and the anti-oxidant effectiveness of selenium is 500 times of vitamin E.The old man should mend selenium in a large number, and every days 200, μ g prevented the damage of free radical and the body of LPO, was conducive to delay senility.

Saturnine molecular pathology mechanism is because the diameter of the electric charge of lead and two ions of calcium and ion is identical, cause mitochondria not differentiate, thereby carry out metabolism in the same way, plumbous the same easy entering in the mitochondria with calcium, but calcium is easy to discharge, lead then is difficult for discharging, and the interior phosphate of plumbous and mitochondria and sulfide combine (its adhesion is higher 1,000,000 times than calcium) securely, constantly are deposited in the mitochondria, cause mitochondria constantly to expand, energy supply mechanism is damaged, even cell is died the lead that dead back cell disengages because lacking to cause death, enter other cell by blood again, acceleration deposits in mitochondria, forms vicious circle, and cytoclasis is serious.Therefore, the elderly should pass through Selenium Supplement, gets rid of excessive lead, thereby delays senility.

5. mending fluorine row aluminium can delay senility

The senile dementia incidence of disease is higher, is about 5%-7%, and as light-duty case is counted, then the incidence of disease reaches 10%, the 70-80 year incidence of disease and can reach 12%-15%.Senile dementia patient's brain contains the aluminium level and obviously raises, and is about normal person's 10-30 doubly.The aluminium aggregation in brain nuclei chromosome, thereby DNA is damaged, the effect that Aluminum very in a small amount may be enough to produce serious antagonism aluminium prevents the generation of senile dementia by mending selenium row aluminium.

Fluorine is related to formation and the structure of skeleton, the elderly lacks the utilization that fluorine then can influence calcium and phosphorus, can cause osteoporosis, fractures, fluorine has the effect that stimulates new bone growth, fluoride is incorporated in the apatite crystal, then is difficult for being dissolved by osteoclast, increases thereby bone is formed, therefore, the elderly should reduce the absorption of aluminium as far as possible, suitably replenishes fluorine, thereby delays senility.

6. " superior trace element spectrum " can make the people have good health and a long life

Human body beneficial's trace element increases along with the age and descends generally speaking, so will all replenish grand, trace element and vitamin, harmful element increases with the age and rises, so want Selenium Supplement, germanium, fluorine, but the essential trace element in centenarian's body then maintains a higher level, is equivalent to the level of 60-70 year healthy old men.Learn from table 1: the calcium in long-lived regional centenarian's hair, magnesium, zinc, copper, strontium, cobalt, nickel, vanadium, selenium etc., the particularly manganese in the hair are 3 times of healthy old men, and harmful element is plumbous and cadmium is more on the low side than healthy old men.Healthy old men at the age of one hundred years old has one " superior trace element spectrum ", this " superior trace element spectrum " can play effect anti-ageing, that prevent always, prevent cardiovascular disease and pre-preventing tumor, the germanium oral absorption can increase oxygen to human body cell, energy oxygenation waste discharge, so mend germanium, a lot of people do not know that germanium is the bodyguard of life, 21 century help germanium, the maintenance god of human health.

The long-lived regional centenarian's hair microelement spectrum in table 1 Hubei Province (μ g/g)

Learn from table 2: the essential trace element in the long lived elder body is along with the increase at age, not only do not reduce, raise on the contrary, especially iron, manganese, strontium, chromium, selenium raise obvious especially in the hair, be considered to the characteristic element of long lived elder, but do not see the appearance of Ge element.

Micronutrient levels (μ g/g) in the table 2 Shenyang City all ages and classes long lived elder hair

Group vitamins, removing free radical material, the serial nutritious material of honeybee are formed % by following proportion by weight

Water soluble vitamin is by vitamin B1, B2, B6, B12 and C, and each equalization of pantothenic acid, folic acid, nicotinic acid, choline and biotin is grouped into.

Liposoluble vitamin is made up of 95% vitamin E and 5% vitamin A, D, K.

The powerful material of removing free radical is made up of following quality

Metallothionein, nanometer selenium, vitamin C, E, β-carrot equal in quality become to be grouped into

Honeybee series is mixed nano powder and is grouped into % by following bee product quality

Form % by each component same amount of honey, royal jelly, melissa powder, propolis, honeycomb, larva of bee, bee pupa, bee imago and pollen pini

Above material

Group vitamins mixing nano powder 30-90;

Remove free radical material mixing nano powder 5-15;

Honeybee series is mixed nano powder 15-45;

Trace element participates in the synthetic of vitamin, influences internal system, and the two is the metabolism of energy catalytic specie all, so have tangible interaction in physiological function.Manganese catalysis is leaned in utilization as vitamin B1, and cobalt is the Main Ingredients and Appearance of cobalamin, brings into play high-effect hematosis.Vitamin E and the selenium function aspect metabolism is worked in coordination.As the vitamin E of radicals scavenging thing with as the selenium that closes selenium glutathione peroxidase composition, remove in the free radical auxiliary additional mutually at the cell anti-oxidative damage.

Zinc participates in the metabolism of vitamin A, promotes vitamin A to mobilize out to utilize from liver, also participates in the synthetic of RBP ELISA.It is reported when VAD, zinc and vitamin A therapeutic alliance effect than single with vitamin A for good.Reason may be that zinc can promote the synthetic of liver RBP ELISA and discharge, thus promoted the circulation of vitamin A in blood, because vitamin A is to circulate in blood with the form with protein bound.

Vitamin C has the absorption of tangible promotion nonheme iron.Vitamin C and iron can form the soluble chelating thing, make iron under high PH condition, also can be dissolved state, are conducive to the absorption of iron.Vitamin C can also accelerate ferritin and discharge iron, is conducive to the mobilization of iron.Vitamin C and plumbous combination in addition forms the lower ascorbic acid lead salt of solubility, thereby reduces plumbous absorption.For the plumbous personnel of long-term contact, take a certain amount of vitamin C every day, to alleviating lead poisoning certain curative effect is arranged.

Vitamin B1 can reduce the toxicity of mercury.Some scholar proves the mercury poisoning polyneuritis, by the treatment of vitamin B1, and the very fast disappearance of symptom.

Vitamin B6 energy catalysis ALA-synzyme, promote the formation of heme and hemoglobin, the synthetic too busy to get away porphin courage again of the synthetic too busy to get away protoporphyrin of ferroheme is former, vitamin B6 is the former coenzyme that must obligato ALA-synzyme when synthetic of porphin courage, so vitamin B6 participates in the synthetic of ferroheme.

In sum, though the trace element in human body, be less than ten thousand of body weight/.But it is indispensable element in the organism, and it is the activator of some enzymes, but must be noted that trace element and the mutual synergy of vitamin on physiological function, and microelement-supplementing is not so good as vitamin and microelement with mending separately.

Below in conjunction with examples of implementation the present invention is further illustrated:

Specific implementation method:

Embodiment 1:

(1) prescription one:

[prescription source] golden Liu Wansu " declaring opinion side ".

[prescription] cultivated land, Ba Qiantian, the stem of noble dendrobium, saline cistanche, monkshood, the fruit of Chinese magnoliavine, Fructus Corni, Chinese cassia tree, the tuber of dwarf lilyturf, Poria cocos, calamus, polygala root.

[effect] nourishing kidney-yin, warm kidney yang, restoring normal coordination between heart and kidney, reducing phlegm by resuscitation.

[application] apoplexy sequela, tongue can not say that by force sufficient impotence can not be used, and dry is the desire drink not, deficiency of kidney essence.

[experimental study]

1. to the influence of life span of drosophila melanogaster: 4% dihuang drink can significantly improve male drosophila average life span (P＜0.05), and 2% dihuang drink can significantly improve female fruit bat average life span (P＜0.05), and male drosophila is only shown prolongation trend.4% and 2% dihuang drink all can prolong female, male drosophila maximum life span, and 2% group is better than 4% group.

2. dihuang drink 20g/kg gives 2 monthly age mouse stomaches 30 days, and contents of mda significantly is lower than water control group (P＜0.05).The 50ml dihuang drink can significantly suppress the rats in vitro liver, brain tissue MDA generates, inhibiting rate 60%.

3. can significant prolongation mouse swimming continuance time; The stock time of significant prolongation mouse under normobaric hypoxia.Can promote congenital adrenal hyperplasia and steroid hormone to discharge increases.

4. experimental cerebral embolism rat model test, dihuang drink can make the major diameter of adrenal gland increase (P＜0.01), and cortical thickness thickens (P＜0.05), and promoting congenital adrenal hyperplasia and steroid hormone to discharge increases.

(5) mouse test, high dose group (25g/kg) can significantly improve hyoscine to the memory impairment (P＜0.01) of mouse.

6. encircle acetimide mouse memory injury experiment, low dose group (12.5g/kg) can significantly be improved mouse memory (P＜0.05).

7. mouse test can improve due to the D-galactolipin brain learning and memory abilities in aging mice that declines.

8. aluminium chloride mouse Model of Dementia test can improve the dementia mice ability of learning and memory, reduces acetylcholine esterase active in the brain tissue.

9. old rats test can make blood, the active obviously raising of brain SOD, GSH-Px, and LPO content obviously descends, and erythrocyte membrane, brain mitochondria membrane fluidity significantly improve.

[clinical research]

1. control sequal of cerebrovascular diseases hemiplegia person 24 examples, it is main that dihuang drink adds the activating qi and collateral medicine, grinds to the powder, each 10g, cure 16 people after March, account for 66.7%, control group 19 examples, oral aspirin, Dipyridamole etc., after 3 months, cure 6 people, account for 31.8%.Two groups of significant differences.The course of disease is the person more than 6 months, dihuang drink group cure rate 42.8%, control group 0%.

2. dihuang drink is controlled general pruritus (liver-kidney deficiency type) 45 examples, cure rate 57.2%, efficient 80.5%.

3. dihuang drink adds flavor and controls apoplexy sequela 120 examples, and 15 days was 1 course for the treatment of, general 2-5 course for the treatment of.Fell ill for 1 week with interior CDPC, quiet 1-2 of Cerebrolysin course for the treatment of, the total effective rate 96% used simultaneously.Some cases is through CT scan, foci disappearance or dwindle.

Prescription two:

[prescription] glossy ganoderma, the fleece-flower root, the fruit of Chinese wolfberry, Poria cocos, Cordyceps sinensis, gynostemma pentaphylla, rhodiola root, the Radix Astragali, sealwort, the bark of eucommia, Radix Angelicae Sinensis, spina date seed, dandelion, pollen.

[effect] is hypotensive, and immunologic function is regulated in reducing blood lipid, delays senility.

The weak diseases of person in middle and old age such as [application] hypertension, high fat of blood.

[experimental study]

1. life span of drosophila melanogaster test: can the female male drosophila average life span of significant prolongation and the life-span (♀ P＜0.05, ♂ P＜0.01).

2. mouse test can make activity of SOD in serum significantly raise (P＜0.01), and MDA content significantly reduces (P＜0.01).

3. the tardy allergy test of mouse: take medicine group and control group ratio, there were significant differences (P＜0.01) for toes swelling degree mean; Serum hemolysin test, antibody product be significantly increased (P＜0.01); The huge chicken red blood cell of biting in abdominal cavity is tested, phagocytic percentage, and phagocytic index significantly improves (P＜0.01) compared with the control.The NK cytoactive does not have significant difference (P＞0.05), proves immunoregulation effect.

Prescription three:

The red plus-minus of [prescription source] Li Congfu doctor's ancient prescription fleece-flower root long-life.

[prescription] fleece-flower root, the fruit of Cherokee rose, the fruit of glossy privet, the seed of Chinese dodder, mulberry fruit, Common St.Paulswort Herb, radix cyathulae.

[effect] tonifying Qi and blood.

[application] body void, prematurely senile person.

[experimental study]

1. life span of drosophila melanogaster test: average life span prolongs 22% than control group, and maximum life span does not have obvious influence.

2. high temperature resistant, the cold resistant of mouse, anti-anoxic, swimming time test with the control group ratio, have obvious effect.

3. acute toxicity test: mouse 125g/kg irritates stomach, observes 72 hours, does not see animal dead and bad reaction.

4. subacute toxicity test: not seeing has harmful effect to blood, liver, kidney and heart function.

[clinical research]

1. senile symptom 90 examples are arranged, benefit smart group in age 50 examples, heart kidney spirit control group 40 examples are taken medicine half a year.Benefit smart group senile symptom in age and physiological function are obviously improved.The control group symptom take a favorable turn, but the functional examination integration counter have increase.

2. controlled senile symptom patient 272 people, medication half a year, ratio before senile symptom integration, physiological function integration, maximal ventilatory volume, timed vital capacity, T3 and the medication all significantly takes a turn for the better.

3. control hypertension 75 examples, efficient 82.7%; Hyperlipidemia 144 examples, efficient 64.6%; Coronary heart disease 35 examples, efficient 77.1%; Low blood pressure 35 examples, efficient 77.1%; Neurasthenia 14 examples, efficient 92.6%.

4. each punish-old year patient 100 example of oral liquid and granule or powder preparation to be taken after being infused in boiling water are improved senile symptom, improve physiological function effect significantly (P＜0.01), and the granule or powder preparation to be taken after being infused in boiling water effect is better.

Prescription four:

[prescription source] clear " the outer vegetarian medical book of generation " life-prolonging pellet plus-minus.

[prescription] RADIX POLYGONI MULTIFLORI PREPARATA, Poria cocos, saline cistanche, mulberry fruit, the seed of Chinese dodder, the fruit of Cherokee rose, fruit of glossy privet, Common St.Paulswort Herb, caulis lonicerae.

[effect] filling liver kidney, benefiting essence-blood strengthens the bone, and tranquilizing mind is strengthened the body resistance to consolidate the constitution.

[application] strengthens immunologic function, and anti-ageing body-building is promoted longevity.

[experimental study]

1. life span of drosophila melanogaster test can prolong average life span 32.4%-55.8% (P＜0.001), prolongs maximum life span 13.5%-24.6% (P＜0.001).

2. rat/mouse labyrinth test can strengthen mouse memory power (P＜0.05).

3. antifatigue, anti-anoxic are arranged, reduce lipofuscin formation, remove the free radical effect, can anti-animal model yang deficiency syndrome and syndrome of spleen deficiency.

4. with adult's 400 times of consumptions (40mg/kg), irritate stomach, mouse no abnormality seen reaction in 48 hours.Rat test (40mg/kg) was irritated stomach 3 months, and routine blood test, hepatic and renal function, pathological tissue inspection there is no unusually.

[clinical research] controls coronary heart disease 110 examples, obvious effective rate 51.8%, efficient 92.7%.

Prescription five:

[prescription source] Hunan College of Traditional Chinese Medicine screening prescription.

[prescription] dried rhizome of rehmannia, the tuber of dwarf lilyturf, the fruit of Chinese wolfberry, the bark of eucommia, raspberry, Chinese cassia tree, red ginseng.

The invigorating the spleen of [effect] kidney-nourishing, nourishing Yin and promoting production of body fluid delays senility.

[application] speen-kidney dificiency.

[experimental study]

1. housefly life test: originally can make the housefly average life span prolong 30% (P＜0.01), be better than the control group oleanolic acid tablet.

2. can obviously prolong the mouse swimming with a load attached to the body time, normal pressure hypoxia endurance time and cold resistant time (P＜0.05).

3. originally can obviously improve liver tissues of rats SOD activity, the SeGSH-Px activity of RBC significantly suppresses the generation of LF and the LPO of the rat heart, hepatic tissue, and suppresses brain MAO-B activity (P＜0.01), is better than fleece-flower root control group.

4. reduce TG, the LDL-C/HDL-C ratio (P＜0.01) of hyperlipemia model rat, significantly raise HDL-C content and HDL-C/TC ratio (P＜0.05), not obvious to the TC effect.

5. after senile rat was fed we, free RNAase activity is lower than control group RNAase activity in lung, brain, the serum did not have significant difference with control group.

6. originally can improve the senile change of senile rat chromatin Structure.The aging that improves Aged Mice liver DNA solubility and hot hyperchromicity, alkaline denaturation hyperchromicity changes, and reduces the fracture of senile rat liver cell nuclear dna single chain.Have the function of protection chromatin Structure and the effect that improves the DNA repair ability.And the effect of antagonism endoxan damage dna arranged.

Prescription six:

Prepared rhizome of rehmannia, saline cistanche, the fruit of Chinese magnoliavine, the seed of Chinese dodder, the seed of Oriental arborvitae, lucid asparagus, frutus cnidii, raspberry, bar halberd, the stem of noble dendrobium, teasel root, rhizoma alismatis, genseng, Chinese yam, polygala root, Fructus Corni, calamus, the osmanthus heart, PORIA ALBA, the bark of eucommia, day male, clock milk powder, clock milk powder times glutinous rehmannia; Forget times polygala root, Poria cocos more; Weak breath is refreshing empty, times raspberry; Desire gloss, times seed of Oriental arborvitae; Wind void, doubly day hero; The cold of insufficiency type, the osmanthus heart; The urine red turbid urine, Poria cocos, rhizoma alismatis; Tell contrary, genseng.The main labor benefit blood of mending goes air-cooledly, and all kinds of diseases and ailments that disappear are all empty not enough, the smart withered refreshing consumption of old man, and the woman hinders breaks extremely.For a long time clothes prolong life, and the Ning Zhi that calms the nerves decide soul, grow the qi and blood train of thought, and it is intelligent to open intelligence development, releases diffusing rheumatism, normal hearing and eyesight, and energy is strong, and skin is pleased the pool, and tolerance is safe decides.The top is to create the name side of lengthening the life mutually by Peng: put down in writing according to " Pengzu biography ": Pengzu surname Qian name clang, and arrive Yin Moshi 767 years old, but still bear one's age well, also once give imperial edict in the time of 270 years old and tucked in the front yard.Passing on from one to another the Pengzu lived 808 years old.This only legend can not make the people believe." the Pengzu ball " of we's name is the effect so as to describing that it is promoted longevity.

Main ingredient among the we is prepared rhizome of rehmannia and saline cistanche.The nourishing the kidney and the liver of prepared rhizome of rehmannia function, replenishing essence is enriched blood, and is regarded as strengthening by means of tonics since ancient times always, and crow sends out the good medicine of lengthening the life.

Prescription seven:

[prescription source] " longevity parent endowment volume ".

[prescription] genseng, radix cyathulae, river Radix Angelicae Sinensis, the dried rhizome of rehmannia, cultivated land, the seed of Oriental arborvitae, the bark of eucommia, the fruit of Chinese wolfberry, the seed of Chinese dodder, grass-leaved sweetflag, the root bark of Chinese wolf-berry, Morinda officinalis.

[preparation] water-honeyed pill.

[effect] filling liver kidney, replenishing qi and blood, nourishing the heart to keep a sound mind, black beard and hair, anti-ageing.

Early ageing, poliosis that [application] liver kidney two void cause.

[experimental study]

1. to the influence of life span of drosophila melanogaster: be control group with physiological saline, containing the not old ball of 1% angle and the not old ball culture medium of 3% angle in the culture medium can make the average life span of female, male both sexes fruit bat and maximum life span prolong, compare with control group, and significant difference (P＜0.05-0.01).

2. can obviously reduce aged mouse blood plasma LPO content; Increase aged mouse erythrocyte sod activity, significantly increase Aged Mice hemolysin content, improve phagocytic rate and the phagocytic index of peritoneal macrophage, compare with the saline control group, and significant difference (P＜0.05-0.01).

3. can obviously prolong the mouse swimming with a load attached to the body time (P＜0.05), obviously prolong the time-to-live (P＜0.05) under the mouse cryogenic conditions.

4. animal experiment can stimulate the T lymphocyte transformation to become sensitized lymphocyte, activates and strengthen the phagocytic function of reticuloendothelial system, improves body's immunological function.

[clinical research]

1. Shenzhen institute of traditional Chinese medicine takes for 30 routine old men with decoction, control group 32 human vitamin Es, every day 100mg.The first two the group Serum LPO content of taking medicine is close, all is higher than the normal person.After taking medicine, two groups of Serum LPO content are starkly lower than (P＜0.05) before the medication, compare no significant difference (P＜0.05) for two groups.Angle's not old ball group SOD increased activity (P＜0.05) after taking medicine, the vitamin E group does not have significant change.

2. medication group is age 60-78 year (average 67.5 years old) healthy old men 60 examples (man 56, woman 4), and control group is Healthy Youth 30 examples (man 25, woman 5), 23 years old mean age.Before the medication, old group Serum LPO, MDA content are significantly higher than young group (P＜0.01), and SOD and GSH-Px activity significantly are lower than young group (P＜0.01).Old group is taken the not old ball of angle after 5 weeks, and Serum LPO, MDA content significantly are lower than take medicine preceding (P＜0.01), but still is higher than young group (P＜0.05); Before SOD, GSH-Px activity are significantly higher than and take medicine (P＜0.05), but still be lower than young group (P＜0.05).

More than seven kinds of prescriptions that lengthen one's life by each component same amount of different prescriptions conventional carbon dioxide abstraction or with 60% alcohol extract method extraction more respectively, filtrate is through thin film evaporation, reclaim ethanol, and be condensed into 1: 1 (be every milliliter and contain source crude drug 1 gram), relative density be 1.03-1.05 liquid extract 1.-7..

Usage: a 70-80 ℃ boiling water is taken after mixing it with water every day 2-3 time.

(2) form % by following macro micro element proportion by weight

Macroelement

Trace element

More than each is grand, each component sum of trace element is 100%;

(3) the superior element spectral of strengthening long-lived crowd is formed (μ g/g) by following proportion by weight

Above beneficial element can only height can not be low, harmful element can only hang down can not be high;

(4) group vitamins, removing free radical material, the serial nutritious material of honeybee are formed % by following proportion by weight

1. group vitamins is formed % by following mass parts

Water soluble vitamin is by vitamin B1, B2, B6, B12 and C, and each same amount material of pantothenic acid, folic acid, nicotinic acid, choline and biotin is formed;

Liposoluble vitamin is made up of 95% vitamin E and 5% vitamin A, D, K;

2. the powerful material of removing free radical is formed % by following mass parts

Metallothionein, nanometer selenium, vitamin C, E, β-carrot equal in quality become to be grouped into;

3. honeybee series mixing nano powder is grouped into % by following bee product quality

Formed by each component same amount of honey, royal jelly, melissa powder, propolis, honeycomb, larva of bee, bee pupa, bee imago and pollen pini;

A kind of superior element spectral group vitamins beverage of life-saving is by grand, trace element group, strengthens the superior element spectral of long-lived crowd, and group vitamins is removed free radical material, the serial nutritious material of honeybee, it is characterized in that: form % by following proportion by weight

The superior element spectral group vitamins beverage of 2 one kinds of life-savings of embodiment is by grand, trace element group, strengthens the superior element spectral of long-lived crowd, and group vitamins is removed free radical material, the serial nutritious material of honeybee, it is characterized in that: form % by following proportion by weight

The superior element spectral group vitamins beverage of 3 one kinds of life-savings of embodiment is by grand, trace element group, strengthens the superior element spectral of long-lived crowd, and group vitamins is removed free radical material, the serial nutritious material of honeybee, it is characterized in that: form % by following proportion by weight

The superior element spectral group vitamins beverage of 4 one kinds of life-savings of embodiment is by grand, trace element group, strengthens the superior element spectral of long-lived crowd, and group vitamins is removed free radical material, the serial nutritious material of honeybee, it is characterized in that: form % by following proportion by weight

The superior element spectral group vitamins beverage of 5 one kinds of life-savings of embodiment is by grand, trace element group, strengthens the superior element spectral of long-lived crowd, and group vitamins is removed free radical material, the serial nutritious material of honeybee, it is characterized in that: form % by following proportion by weight

The superior element spectral group vitamins beverage of 6 one kinds of life-savings of embodiment is by grand, trace element group, strengthens the superior element spectral of long-lived crowd, and group vitamins is removed free radical material, the serial nutritious material of honeybee, it is characterized in that: form % by following proportion by weight

The superior element spectral group vitamins beverage of 7 one kinds of life-savings of embodiment is by grand, trace element group, strengthens the superior element spectral of long-lived crowd, and group vitamins is removed free radical material, the serial nutritious material of honeybee, it is characterized in that: form % by following proportion by weight

Claims (1)

1. the superior element spectral group vitamins beverage of a life-saving is characterized in that: form % by following proportion by weight

Wherein 1.-7. the Chinese medicine liquid extract number is made up of following prescription:

1. cultivated land, Ba Qiantian, the stem of noble dendrobium, saline cistanche, monkshood, the fruit of Chinese magnoliavine, Fructus Corni, Chinese cassia tree, the tuber of dwarf lilyturf, Poria cocos, calamus, polygala root;

2. glossy ganoderma, the fleece-flower root, the fruit of Chinese wolfberry, Poria cocos, Cordyceps sinensis, gynostemma pentaphylla, rhodiola root, the Radix Astragali, sealwort, the bark of eucommia, Radix Angelicae Sinensis, spina date seed, dandelion, pollen pini;

3. the fleece-flower root, the fruit of Cherokee rose, the fruit of glossy privet, the seed of Chinese dodder, mulberry fruit, Common St.Paulswort Herb, radix cyathulae;

4. RADIX POLYGONI MULTIFLORI PREPARATA, Poria cocos, saline cistanche, mulberry fruit, the seed of Chinese dodder, the fruit of Cherokee rose, fruit of glossy privet, Common St.Paulswort Herb, caulis lonicerae;

5. the dried rhizome of rehmannia, the tuber of dwarf lilyturf, the fruit of Chinese wolfberry, the bark of eucommia, raspberry, Chinese cassia tree, red ginseng;

6. prepared rhizome of rehmannia, saline cistanche, the fruit of Chinese magnoliavine, the seed of Chinese dodder, the seed of Oriental arborvitae, lucid asparagus, frutus cnidii, raspberry, bar halberd, the stem of noble dendrobium, teasel root, rhizoma alismatis, genseng, Chinese yam, polygala root, Fructus Corni, calamus, the osmanthus heart, PORIA ALBA, the bark of eucommia, day male, clock milk powder;

7. genseng, radix cyathulae, river Radix Angelicae Sinensis, the dried rhizome of rehmannia, cultivated land, the seed of Oriental arborvitae, the bark of eucommia, the fruit of Chinese wolfberry, the seed of Chinese dodder, grass-leaved sweetflag, the root bark of Chinese wolf-berry, Morinda officinalis;

(2) form % by following macro micro element proportion by weight

Macroelement

Trace element

More than each is grand, each component sum of trace element is 100%;

(3) the superior element spectral of strengthening long-lived crowd is formed (μ g/g) by following proportion by weight

Above beneficial element can only height can not be low, harmful element can only hang down can not be high;

(4) group vitamins, removing free radical material, the serial nutritious material of honeybee are formed % by following proportion by weight

1. group vitamins is formed % by following mass parts

Water soluble vitamin is by vitamin B1, B2, B6, B12 and C, and each same amount material of pantothenic acid, folic acid, nicotinic acid, choline and biotin is formed;

Liposoluble vitamin is made up of 95% vitamin E and 5% vitamin A, D, K;

2. the powerful material of removing free radical is formed % by following mass parts

Metallothionein, nanometer selenium, vitamin C, E, β-carrot equal in quality become to be grouped into;

3. honeybee series mixing nano powder is grouped into % by following bee product quality

Formed by each component same amount of honey, royal jelly, melissa powder, propolis, honeycomb, larva of bee, bee pupa, bee imago and pollen pini;