CN103211729A - Skin-care composition with anti-aging effect - Google Patents
Skin-care composition with anti-aging effect Download PDFInfo
- Publication number
- CN103211729A CN103211729A CN2013101315127A CN201310131512A CN103211729A CN 103211729 A CN103211729 A CN 103211729A CN 2013101315127 A CN2013101315127 A CN 2013101315127A CN 201310131512 A CN201310131512 A CN 201310131512A CN 103211729 A CN103211729 A CN 103211729A
- Authority
- CN
- China
- Prior art keywords
- extract
- parts
- skin
- fructus
- care composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a skin-care composition with an anti-aging effect. The skin-care composition comprises the following components in parts by weight: 1-20 parts of elderberry extract, 1-20 parts of ginkgo leaf extract, 1-20 parts of black pepper extract, 1-20 parts of radix scutellariae extract, 1-20 parts of hawthorn extract, 1-20 parts of salvinia natans extract, 1-20 parts of kudzu vine root extract, 1-20 parts of centella extract and 1-20 parts of white gourd extract. The skin-care composition with the anti-ageing effect disclosed by the invention can be used for strengthening anti-oxidation capability of skin tissues, lowering the free radical content of the skin tissues and delaying aging of the skin.
Description
Technical field
The present invention relates to a kind of skin care compositions, particularly relate to a kind of skin care compositions with anti-aging effects.
Background technology
At present, along with the raising of people's living standard and aesthetical standard, people more and more pay attention to the nursing of skin.Cosmetics should have higher safety as a kind of special skin care product,, nonirritant nontoxic to human body skin.In recent years, tend to from natural plants, seek natural component safely and efficiently for toxicity and the increasing scientific research person of irritating doubt to chemical toilet, thus develop a series of action temperature and, the cosmetics of nontoxic non-irritating Chinese herbal medicine extract and natural plant composition.The uphold nature in recent years in the west, under the influence away from the theory of chemical contamination, the European has also selected natural component more and has used synthetic less in the use of cosmetics, China is with the Chinese herbal medicine nursing and treat the history that disease also had several thousand, and the market value of Chinese medicine cosmetics and prospect will be very huge.
Summary of the invention
The objective of the invention is to overcome the deficiencies in the prior art, a kind of skin care compositions with anti-aging effects is provided.
Technical scheme of the present invention is summarized as follows:
A kind of skin care compositions with anti-aging effects comprises following component by weight:
Ramulus Sambuci Williamsii extract 1-20 part, Folium Ginkgo extract 1-20 part, Fructus Piperis extract 1-20 part, Radix Scutellariae extract 1-20 part, Fructus Crataegi extract 1-20 part, Japanese pagodatree leaf extract 1-20 part, Radix Puerariae extract 1-20 part, Herba Centellae extract 1-20 part, Fructus Benincasae extract 1-20 part.
Preferably: Ramulus Sambuci Williamsii extract is 10 parts, and Folium Ginkgo extract is 10 parts, and Fructus Piperis extract is 1 part, Radix Scutellariae extract is 3 parts, and Fructus Crataegi extract is 3 parts, and the Japanese pagodatree leaf extract is 3 parts, Radix Puerariae extract is 5 parts, and Herba Centellae extract is 2 parts, and the Fructus Benincasae extract is 2 parts.
The present composition can strengthen the oxidation resistance of skin histology, reduces the skin histology free-radical contents, the effect of performance delay skin aging.
The specific embodiment
The present invention is further illustrated below in conjunction with specific embodiment.
Embodiment 1
A kind of skin care compositions with anti-aging effects comprises following component by weight:
Ramulus Sambuci Williamsii extract is 10 parts, and Folium Ginkgo extract is 10 parts, and Fructus Piperis extract is 1 part, and Radix Scutellariae extract is 3 parts, and Fructus Crataegi extract is 3 parts, and the Japanese pagodatree leaf extract is 3 parts, and Radix Puerariae extract is 5 parts, and Herba Centellae extract is 2 parts, and the Fructus Benincasae extract is 2 parts.
Embodiment 2
A kind of skin care compositions with anti-aging effects comprises following component by weight:
1 part of Ramulus Sambuci Williamsii extract, 20 parts of Folium Ginkgo extract, 5 parts of Fructus Piperis extracts, 1 part of Radix Scutellariae extract, 20 parts of Fructus Crataegi extracts, 5 parts of Japanese pagodatree leaf extracts, 1 part of Radix Puerariae extract, 20 parts of Herba Centellae extracts, 5 parts of Fructus Benincasae extracts.
Embodiment 3
A kind of skin care compositions with anti-aging effects comprises following component by weight:
10 parts of Ramulus Sambuci Williamsii extracts, 1 part of Folium Ginkgo extract, 20 parts of Fructus Piperis extracts, 5 parts of Radix Scutellariae extracts, 1 part of Fructus Crataegi extract, 20 parts of Japanese pagodatree leaf extracts, 10 parts of Radix Puerariae extracts, 1 part of Herba Centellae extract, 20 parts of Fructus Benincasae extracts.
Embodiment 4
A kind of skin care compositions with anti-aging effects comprises following component by weight:
20 parts of Ramulus Sambuci Williamsii extracts, 10 parts of Folium Ginkgo extract, 1 part of Fructus Piperis extract, 20 parts of Radix Scutellariae extracts, 5 parts of Fructus Crataegi extracts, 1 part of Japanese pagodatree leaf extract, 20 parts of Radix Puerariae extracts, 5 parts of Herba Centellae extracts, 1 part of Fructus Benincasae extract.
Embodiment 5
Contain the preparation of the essence of a kind of skin care compositions with anti-aging effects of the present invention:
Take by weighing the compositions of the various embodiments described above, (weight portion of each component changes gram among each embodiment) adds carbopol 940 resin 2g again, 1,3 butanediol 50g, and hydroxyethyl-cellulose 1g, triethanolamine 1.8g, deionized water adds to 1000g, and mixing gets final product.
Embodiment 6
Experiment
One, SOD, MDA, Determination of Hydroxyproline
1 material
1.1 animal.60 of SD rats, body weight 180 ± 20g, ♀ ♂ half and half.
1.2 material and reagent.Skin care compositions with anti-aging effects of the present invention; SOD mensuration test kit, MDA measure test kit, the hydroxyproline determination test kit builds up bio-engineering research by Nanjing and provides.
1.3 key instrument.Ultraviolet lamp tube (the Nanjing China limited department of forceful electric power, 80WUVA lamp and 160W UVB lamp); Uitraviolet intensity analyzer (Mei Ying Pu, Shanghai instrument and meter Manufacturing Co., Ltd, model: the ZQJ-254 type); Ultra-violet and visible spectrophotometer (east of a river, Suzhou precision instrument company limited, model: 752N); (magnetoelectricity scarabaeidae skill company limited, model: the T10 type) are got in Shanghai in tissue refiner.
2 methods
2.1 animal grouping and administration.
Be divided into 6 groups at random;
Matched group (being normal group): do not carry out ultra-vioket radiation and not administration;
Matrix group: rat was smeared the mixed liquor of adjuvant (embodiment 5 removes the remainder of the skin care compositions with anti-aging effects) in preceding 10 minutes carrying out ultraviolet radiation.
Of the present invention group (essence of the skin care compositions preparation with anti-aging effects of embodiment 1-4 preparation, be called for short: skin care compositions) rat was smeared skin care compositions of the present invention in preceding 10 minutes carrying out ultraviolet radiation.
2.2 modeling
Except that normal group, all the other respectively organize rat with mass concentration 10%Na
2The S aqueous solution loses hair or feathers to center, back skin, exposes 2cm * 2cm size skin.Simulation UV irradiation.Radiation source: UVA lamp 80W and UVB lamp 160W.Light source shines at the about 40cm of distance rat place.Shine 1 the 1st every day in week, each 1h, and the 2nd week rose and shines 2 times every day, each 40min, prolonged exposure to accumulative total exposure dose reaches UVA 304.5J/cm
2, UVB 6.3J/cm
2
2.3 draw materials.
Behind the 60th day last irradiation 2h, take off cervical vertebra and put to death rat, get the about 1cm of depilation position skin
2, the work done in the manner of a certain author hydroxyproline content detects; Get about surplus depilation skin of back 0.1g, work done in the manner of a certain author MDA and SOD detect.
2.4 hydroxyproline content detects.
Accurately take by weighing the 0.050g skin histology, add hydrolysis 40min in 95～100 ℃ of hydrolyzed solutions, centrifugal 10min gets the supernatant strictness and detects by hydroxyproline determination test kit operating instruction.
2.5MDA, the SOD content detection.
Got skin histology about 0.1g with pre-cold saline rinsing, remove connective tissue and subcutaneous fat, filter paper is wiped away dried weighing, in pouring into after tissue shredded in the cut homogenate pipe, measure the pre-cold saline of 9 times of these skin histology weight, take a morsel earlier to pour into homogenate 15min in the frozen water is housed in the piece of tissue homogenizer, pour the residue normal saline then into, make 10% tissue homogenate.It is standby that 10% tissue homogenate is got supernatant with the centrifugal 10min of 3000r/min.MDA is pressed in strictness, SOD test kit operating instruction detects.
2.6 statistical method.
(X ± S) expression is carried out check between variance analysis and group with SPSS11.5 software to the result with mean ± standard deviation.
3 results
3.1 rat skin general state.
The normal rats skin surface is smooth flexible, and texture is clear, no wrinkle; There is obvious erythema on matrix group rat skin surface, follows the string and gloss, and keratinization of epidermis, coarse companion's desquamation have dark fold; Skin care compositions group rat skin wrinkle of the present invention is not obvious, near normal rats skin.
3.2 various embodiments of the present invention skin care compositions group is to the influence of rat skin SOD, MDA.
See Table 1.With normal group relatively, active significantly reduce (P＜0.01) of matrix group skin SOD, MDA level significantly raise (P＜0.01).Skin care compositions group of the present invention is compared with matrix group, and the skin SOD activity all obviously raises (P＜0.01), MDA content obviously reduces (P＜0.01).
3.3 the essence of skin care compositions preparation of the present invention is to the influence of rat skin hydroxyproline content.See Table 1.
Table 1 pharmaceutical composition of the present invention to the influence of rat skin SOD, MDA, hydroxyproline content (X ± S, N=10)
Annotate: compare * * P＜0.01 with matrix group.
In this experimental result, skin care compositions group of the present invention can obviously strengthen photoaging rat skin tissue SOD activity, reduces MDA content, shows that the present composition can strengthen the oxidation resistance of skin histology, reduce the skin histology free-radical contents, the effect of performance delay skin aging.
Using method:
The said goods evenly is applied in facial getting final product in right amount.
Through the essence of 80 people's trial edition inventive embodiment 1-4 preparation of compositions 30 days, every group 20 people, result showed, the essence of preparation of compositions of the present invention can be put forward the bright colour of skin, and effective percentage 95% does not have irritated, non-stimulated.
Below the preparation of each extract be in order to enable those skilled in the art to implement the present invention, but the present invention is not imposed any restrictions, experimental results show that the commercially available various extracts similar to following preparation method, also can be used for the present invention.
Ramulus Sambuci Williamsii extract is to make with following method:
Take by weighing Ramulus Sambuci Williamsii, the volumetric concentration that adds 3 times of described Ramulus Sambuci Williamsii quality is 75% ethanol water, put in the ultrasonic waves for cleaning instrument of 85kHz ultrasonic 4 minutes, the volumetric concentration that adds 7 times of described Ramulus Sambuci Williamsii quality again is 75% ethanol water, normal pressure reflux 3 hours, filter concentrated filtrate, drying.
Folium Ginkgo extract is to make with following method:
Take by weighing Folium Ginkgo, the volumetric concentration that adds 8 times of described Folium Ginkgo quality is 70% ethanol water, put in the ultrasonic waves for cleaning instrument of 85kHz ultrasonic 4 minutes, the volumetric concentration that adds 8 times of described Folium Ginkgo quality again is 70% ethanol water, normal pressure reflux 3 hours, filter concentrated filtrate, drying.
Fructus Piperis extract is to make with following method:
Take by weighing Fructus Piperis, the volumetric concentration that adds 10 times of described Fructus Piperis quality is 75% ethanol water, puts in the ultrasonic waves for cleaning instrument of 85kHz ultrasonic 4 minutes, the volumetric concentration that adds 5 times of described Fructus Piperis quality again is 75% ethanol water, and normal pressure reflux 3 hours filters, concentrated filtrate, drying.
Radix Scutellariae extract is to make with following method:
Take by weighing Radix Scutellariae, the volumetric concentration that adds 10 times of described Radix Scutellariae quality is 60% ethanol water, put in the ultrasonic waves for cleaning instrument of 85kHz ultrasonic 4 minutes, the volumetric concentration that adds 10 times of described Radix Scutellariae quality again is 60% ethanol water, normal pressure reflux 3 hours, filter concentrated filtrate, drying.
Fructus Crataegi extract is to make with following method:
Take by weighing Fructus Crataegi, add the water of 14 times of described Fructus Crataegi quality, put in the ultrasonic waves for cleaning instrument of 85kHz ultrasonic 4 minutes, add the water of 12 times of described Fructus Crataegi quality again, normal pressure reflux 3 hours filters concentrated filtrate, drying.
The Japanese pagodatree leaf extract is to make with following method:
Take by weighing Japanese pagodatree leaf, the volumetric concentration that adds 20 times of described Japanese pagodatree leaf quality is 3% borax solution, puts in the ultrasonic waves for cleaning instrument of 85kHz ultrasonic 4 minutes, the volumetric concentration that adds 20 times of described Japanese pagodatree leaf quality again is 3% borax solution, and normal pressure reflux 3min filters, concentrated filtrate, drying.
Radix Puerariae extract is to make with following method:
Take by weighing Radix Puerariae, the volumetric concentration that adds 9 times of described Radix Puerariae quality is 30% ethanol water, puts in the ultrasonic waves for cleaning instrument of 85kHz ultrasonic 4 minutes, the volumetric concentration that adds 9 times of described Radix Puerariae quality again is 30% ethanol water, and normal pressure reflux 3 hours filters, concentrated filtrate, drying.
Herba Centellae extract is to make with following method:
Take by weighing Herba Centellae, add the ethanol water of 12 times of described Herba Centellae quality, put in the ultrasonic waves for cleaning instrument of 85kHz ultrasonic 4 minutes, add the ethanol water of 12 times of described Herba Centellae quality again, normal pressure reflux 3 hours filters concentrated filtrate, drying.
The Fructus Benincasae extract is to make with following method:
Take by weighing Fructus Benincasae, the volumetric concentration that adds 10 times of described Fructus Benincasae quality is 60% ethanol water, put in the ultrasonic waves for cleaning instrument of 85kHz ultrasonic 4 minutes, the volumetric concentration that adds 10 times of described Fructus Benincasae quality again is 60% ethanol water, normal pressure reflux 3 hours, filter concentrated filtrate, drying.
Claims (2)
1. skin care compositions with anti-aging effects is characterized in that comprising by weight following component:
Ramulus Sambuci Williamsii extract 1-20 part, Folium Ginkgo extract 1-20 part, Fructus Piperis extract 1-20 part, Radix Scutellariae extract 1-20 part, Fructus Crataegi extract 1-20 part, Japanese pagodatree leaf extract 1-20 part, Radix Puerariae extract 1-20 part, Herba Centellae extract 1-20 part, Fructus Benincasae extract 1-20 part.
2. skin care compositions according to claim 1, it is characterized in that described Ramulus Sambuci Williamsii extract is 10 parts, Folium Ginkgo extract is 10 parts, Fructus Piperis extract is 1 part, and Radix Scutellariae extract is 3 parts, and Fructus Crataegi extract is 3 parts, the Japanese pagodatree leaf extract is 3 parts, Radix Puerariae extract is 5 parts, and Herba Centellae extract is 2 parts, and the Fructus Benincasae extract is 2 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310131512.7A CN103211729B (en) | 2013-04-16 | 2013-04-16 | Skin-care composition with anti-aging effect |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310131512.7A CN103211729B (en) | 2013-04-16 | 2013-04-16 | Skin-care composition with anti-aging effect |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103211729A true CN103211729A (en) | 2013-07-24 |
| CN103211729B CN103211729B (en) | 2015-07-22 |
Family
ID=48810126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310131512.7A Expired - Fee Related CN103211729B (en) | 2013-04-16 | 2013-04-16 | Skin-care composition with anti-aging effect |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103211729B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104586727A (en) * | 2015-01-08 | 2015-05-06 | 福建春辉生物工程有限公司 | Anti-radiation plant-tea oil water replenishing liquid |
| CN104666176A (en) * | 2015-02-03 | 2015-06-03 | 天津科丝美特生物科技有限公司 | Skin care composition having anti-aging function |
| CN107353282A (en) * | 2017-06-28 | 2017-11-17 | 卓宇哲 | The technique of extracting high purity puerarin and a variety of rare medical components from the root of kudzu vine |
| CN110638860A (en) * | 2019-09-03 | 2020-01-03 | 山西大学 | Scutellaria baicalensis leaf extract and preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1410045A (en) * | 2001-09-29 | 2003-04-16 | 焦柏忠 | Cosmetics made of nano natural material |
| CN103070810A (en) * | 2013-02-06 | 2013-05-01 | 成都山信药业有限公司 | Anti-skin-aging composition |
| CN103405380A (en) * | 2013-09-06 | 2013-11-27 | 重庆市中药研究院 | White fungus skin-care composition and application thereof |
-
2013
- 2013-04-16 CN CN201310131512.7A patent/CN103211729B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1410045A (en) * | 2001-09-29 | 2003-04-16 | 焦柏忠 | Cosmetics made of nano natural material |
| CN103070810A (en) * | 2013-02-06 | 2013-05-01 | 成都山信药业有限公司 | Anti-skin-aging composition |
| CN103405380A (en) * | 2013-09-06 | 2013-11-27 | 重庆市中药研究院 | White fungus skin-care composition and application thereof |
Non-Patent Citations (3)
| Title |
|---|
| 吴伟: "中药抗衰老与清除自由基损伤", 《新中医》 * |
| 徐大鹏: "抗衰老中药的药理分析与研究", 《科技与企业》 * |
| 麦其鹏等: "复方抗衰老中药的性味归经与药效的BP神经网络研究", 《中国中药杂志》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104586727A (en) * | 2015-01-08 | 2015-05-06 | 福建春辉生物工程有限公司 | Anti-radiation plant-tea oil water replenishing liquid |
| CN104586727B (en) * | 2015-01-08 | 2017-10-10 | 福建春辉生物工程有限公司 | A kind of plant and tea oil radiation proof moisturizing liquid |
| CN104666176A (en) * | 2015-02-03 | 2015-06-03 | 天津科丝美特生物科技有限公司 | Skin care composition having anti-aging function |
| CN107353282A (en) * | 2017-06-28 | 2017-11-17 | 卓宇哲 | The technique of extracting high purity puerarin and a variety of rare medical components from the root of kudzu vine |
| CN110638860A (en) * | 2019-09-03 | 2020-01-03 | 山西大学 | Scutellaria baicalensis leaf extract and preparation method and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103211729B (en) | 2015-07-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105769698B (en) | A kind of cosmetic composition and its application without preservative | |
| CN101068525B (en) | Compositions and methods of their use for improving the condition and appearance of skin | |
| CN104434747B (en) | A kind of face cream with senile-resistant efficacy and preparation method thereof | |
| CN103027867A (en) | Finishing liquor applied on wet tissue and available for after-sun makeup removal and repair | |
| CN103126972B (en) | Skin care composition with anti-aging and whitening effects | |
| CN1253146C (en) | Cosmetic skin caring cream | |
| CN103845277A (en) | Natural traditional Chinese medicine mask powder as well as preparation method and mask thereof | |
| CN103211729B (en) | Skin-care composition with anti-aging effect | |
| CN102772355B (en) | Skin care composition with light aging resisting effect | |
| CN104984074A (en) | Feature-beautifying skin-care product and production method and application thereof | |
| CN104491003A (en) | Jiawei Yupingfeng gel, preparation method and purpose thereof | |
| CN104367522A (en) | Stretch mark removing beauty powder and preparation method thereof | |
| CN104127331A (en) | Skin-protecting product for improving skin anti-allergy and regeneration capacities and preparation method thereof | |
| CN105616334A (en) | Skin-caring composition having antioxidation and whitening effects | |
| CN104352397A (en) | Skin caring composition with effects of resisting light aging and whitening | |
| CN102743313B (en) | Natural medicinal composition for delaying skin aging and application thereof | |
| CN104434767A (en) | Tricholoma matsutake mask powder | |
| CN105560085B (en) | Iridin sunlight screening skin-protecting product | |
| CN108703911A (en) | A kind of composition and its preparation method and application with moisturizing white-skinned face function | |
| CN113332197A (en) | Plant sunscreen cream and preparation method thereof | |
| Minamisawa et al. | Protective effects of Jin Bai Mei Yan Prescription on oxidative damage and photoaging induced by ultraviolet B in HaCaT cells | |
| CN104306317A (en) | Plant skin-protecting composition with anti-oxidation and whitening effects | |
| CN111939107A (en) | Traditional Chinese medicine liquid with beautifying effect | |
| CN103330743A (en) | Skin care composition with function of retaining youthful looks | |
| CN110787123A (en) | Medical-grade cosmetic for removing freckles and wrinkles and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150722 Termination date: 20160416 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |