CN103168235A - 用于分析受试者血样中疾病标记物的存在的方法 - Google Patents
用于分析受试者血样中疾病标记物的存在的方法 Download PDFInfo
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- CN103168235A CN103168235A CN2011800449000A CN201180044900A CN103168235A CN 103168235 A CN103168235 A CN 103168235A CN 2011800449000 A CN2011800449000 A CN 2011800449000A CN 201180044900 A CN201180044900 A CN 201180044900A CN 103168235 A CN103168235 A CN 103168235A
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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Abstract
Description
Claims (16)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36483110P | 2010-07-16 | 2010-07-16 | |
EP10169897.5 | 2010-07-16 | ||
US61/364,831 | 2010-07-16 | ||
EP10169897 | 2010-07-16 | ||
EP11158912 | 2011-03-18 | ||
EP11158912.3 | 2011-03-18 | ||
EP11167973 | 2011-05-27 | ||
EP11167973.4 | 2011-05-27 | ||
PCT/NL2011/050518 WO2012008839A2 (en) | 2010-07-16 | 2011-07-15 | A method of analysing a blood sample of a subject for the presence of a disease marker |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103168235A true CN103168235A (zh) | 2013-06-19 |
CN103168235B CN103168235B (zh) | 2016-01-13 |
Family
ID=45469975
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201180044900.0A Expired - Fee Related CN103168235B (zh) | 2010-07-16 | 2011-07-15 | 用于分析受试者血样中疾病标记物的存在的方法 |
Country Status (11)
Country | Link |
---|---|
US (1) | US10174364B2 (zh) |
EP (1) | EP2593787B1 (zh) |
JP (2) | JP6076901B2 (zh) |
CN (1) | CN103168235B (zh) |
AU (1) | AU2011277178B2 (zh) |
BR (1) | BR112013001136B1 (zh) |
CA (1) | CA2805586C (zh) |
HK (1) | HK1186767A1 (zh) |
MX (1) | MX351242B (zh) |
SG (1) | SG187101A1 (zh) |
WO (1) | WO2012008839A2 (zh) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10174364B2 (en) | 2010-07-16 | 2019-01-08 | Stichting Vu-Vumc | Method of analysing a blood sample of a subject for the presence of a disease marker |
US10174365B2 (en) | 2011-03-18 | 2019-01-08 | Stichting Vu-Vumc | Method of analysing a blood sample of a subject for the presence of a disease marker |
CN109642259A (zh) * | 2017-02-17 | 2019-04-16 | 阿姆斯特丹自由大学医学中心基金会 | 使用肿瘤教育的血小板的针对癌症的群智能增强的诊断和治疗选择 |
CN112094907A (zh) * | 2019-06-18 | 2020-12-18 | 西湖大学 | 外周血红细胞微核dna及其应用 |
WO2021190124A1 (zh) * | 2020-03-23 | 2021-09-30 | 南京梅傲红清生物科技有限公司 | 红细胞核酸在鉴定肿瘤的突变类型中的应用 |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2015528895A (ja) * | 2012-06-15 | 2015-10-01 | オートテリック エルエルシー | Fsh、lh、hcgおよびbnp用ポイントオブケアデバイスによる個別化医療のための方法および組成物 |
WO2014134790A1 (zh) * | 2013-03-06 | 2014-09-12 | 广州百赫医疗信息科技有限公司 | 神经纤维瘤病pcr诊断试剂盒 |
EP3134546A4 (en) | 2014-04-24 | 2017-12-06 | Dana-Farber Cancer Institute, Inc. | Tumor suppressor and oncogene biomarkers predictive of anti-immune checkpoint inhibitor response |
WO2016172576A1 (en) | 2015-04-22 | 2016-10-27 | Board Of Trustees Of Northern Illinois University | Non-invasive occular biomarkers for early diagnosis of diseases |
US11667975B2 (en) * | 2018-04-24 | 2023-06-06 | Washington University | Methods and systems for noninvasive and localized brain liquid biopsy using focused ultrasound |
Citations (4)
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WO2002070738A2 (en) * | 2001-03-07 | 2002-09-12 | Andre Schuh | Diagnosis and treatment of blood disorders |
GB2380194A (en) * | 2001-10-01 | 2003-04-02 | Roger Michael Marchbanks | Mitochondrial mutation associated with schizophrenia |
CN1922304A (zh) * | 2003-10-31 | 2007-02-28 | 维特克公司 | 用于检测循环肿瘤和内皮细胞的血液测试样机和方法 |
CN101310025A (zh) * | 2005-09-15 | 2008-11-19 | 阿尔特弥斯康复公司 | 分析物富集的系统和方法 |
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US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
CA1323293C (en) | 1987-12-11 | 1993-10-19 | Keith C. Backman | Assay using template-dependent nucleic acid probe reorganization |
US5185244A (en) * | 1989-12-08 | 1993-02-09 | Emory University | Genetic test for hereditary neuromuscular disease |
US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
US5270184A (en) | 1991-11-19 | 1993-12-14 | Becton, Dickinson And Company | Nucleic acid target generation |
US5719028A (en) | 1992-12-07 | 1998-02-17 | Third Wave Technologies Inc. | Cleavase fragment length polymorphism |
SE9400522D0 (sv) | 1994-02-16 | 1994-02-16 | Ulf Landegren | Method and reagent for detecting specific nucleotide sequences |
US5942391A (en) | 1994-06-22 | 1999-08-24 | Mount Sinai School Of Medicine | Nucleic acid amplification method: ramification-extension amplification method (RAM) |
WO2000040749A2 (en) | 1999-01-06 | 2000-07-13 | Genenews Inc. | Method for the detection of gene transcripts in blood and uses thereof |
CA2370884A1 (en) * | 1999-04-20 | 2000-10-26 | Mitokor | Single nucleotide polymorphisms in mitochondrial genes that segregate with alzheimer's disease |
US6977162B2 (en) | 2002-03-01 | 2005-12-20 | Ravgen, Inc. | Rapid analysis of variations in a genome |
WO2005111231A2 (en) | 2004-05-11 | 2005-11-24 | Heptest Laboratories, Inc. | Compositions, kit and one-step method for monitoring compounds having anti-factor xa and/or anti factor iia activities |
FR2877013A1 (fr) * | 2004-10-27 | 2006-04-28 | Assist Publ Hopitaux De Paris | Indentification d'une mutation de jak2 impliquee dans la polyglobulie de vaquez |
CN105823877B (zh) * | 2005-06-22 | 2022-02-25 | 约翰·霍普金斯大学 | 卵巢癌的生物标记:ctap3-相关蛋白质 |
US20070059774A1 (en) | 2005-09-15 | 2007-03-15 | Michael Grisham | Kits for Prenatal Testing |
EP1931800A4 (en) | 2005-09-15 | 2011-06-15 | Artemis Health Inc | SYSTEMS AND METHODS FOR ENRICHING ANALYTES |
US20090042869A1 (en) * | 2007-06-20 | 2009-02-12 | University Of Utah Research Foundation | SIGNAL-DEPENDENT SPLICING OF TISSUE FACTOR PRE-mRNA IN PLATELET CELLS |
US11634747B2 (en) | 2009-01-21 | 2023-04-25 | Streck Llc | Preservation of fetal nucleic acids in maternal plasma |
EP2336353A1 (en) | 2009-12-17 | 2011-06-22 | febit holding GmbH | miRNA fingerprints in the diagnosis of diseases |
EP2593787B1 (en) | 2010-07-16 | 2018-07-04 | Stichting VUmc | A method of analysing a blood sample of a subject for the presence of a disease marker |
JP5934726B2 (ja) | 2011-03-18 | 2016-06-15 | フェレニヒング フォール クリステリック ホーヘル オンデルウィス,ウェテンシャペリク オンデルツォーケン パティエンテンツォルフ | 疾患マーカーの存在を被験者の血液サンプルで分析する方法 |
WO2013022342A1 (en) | 2011-08-09 | 2013-02-14 | Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patiëntenzorg | A method of analysing a blood sample of a subject for the presence of a foetal disease or condition marker |
-
2011
- 2011-07-15 EP EP11736199.8A patent/EP2593787B1/en active Active
- 2011-07-15 WO PCT/NL2011/050518 patent/WO2012008839A2/en active Application Filing
- 2011-07-15 CA CA2805586A patent/CA2805586C/en active Active
- 2011-07-15 JP JP2013519616A patent/JP6076901B2/ja active Active
- 2011-07-15 CN CN201180044900.0A patent/CN103168235B/zh not_active Expired - Fee Related
- 2011-07-15 BR BR112013001136-0A patent/BR112013001136B1/pt not_active IP Right Cessation
- 2011-07-15 AU AU2011277178A patent/AU2011277178B2/en not_active Ceased
- 2011-07-15 MX MX2013000606A patent/MX351242B/es active IP Right Grant
- 2011-07-15 SG SG2013003553A patent/SG187101A1/en unknown
- 2011-07-15 US US13/809,960 patent/US10174364B2/en active Active
-
2013
- 2013-12-18 HK HK13114039.9A patent/HK1186767A1/zh not_active IP Right Cessation
-
2016
- 2016-07-06 JP JP2016133808A patent/JP6171057B2/ja not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2002070738A2 (en) * | 2001-03-07 | 2002-09-12 | Andre Schuh | Diagnosis and treatment of blood disorders |
GB2380194A (en) * | 2001-10-01 | 2003-04-02 | Roger Michael Marchbanks | Mitochondrial mutation associated with schizophrenia |
CN1922304A (zh) * | 2003-10-31 | 2007-02-28 | 维特克公司 | 用于检测循环肿瘤和内皮细胞的血液测试样机和方法 |
CN101310025A (zh) * | 2005-09-15 | 2008-11-19 | 阿尔特弥斯康复公司 | 分析物富集的系统和方法 |
Non-Patent Citations (3)
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DMITRI V .GNATENKO ET AL: "Class prediction models of thrombocytosis using genetic biomarkers", 《BLOOD》 * |
MICHAEL GIRARDOT ET AL: "miR-28 is a thrombopoietin receptor targeting microRNA detected in a fraction of myeloproliferative neoplasm patient platelets", 《BLOOD》 * |
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10174364B2 (en) | 2010-07-16 | 2019-01-08 | Stichting Vu-Vumc | Method of analysing a blood sample of a subject for the presence of a disease marker |
US10174365B2 (en) | 2011-03-18 | 2019-01-08 | Stichting Vu-Vumc | Method of analysing a blood sample of a subject for the presence of a disease marker |
CN109642259A (zh) * | 2017-02-17 | 2019-04-16 | 阿姆斯特丹自由大学医学中心基金会 | 使用肿瘤教育的血小板的针对癌症的群智能增强的诊断和治疗选择 |
CN112094907A (zh) * | 2019-06-18 | 2020-12-18 | 西湖大学 | 外周血红细胞微核dna及其应用 |
CN112094907B (zh) * | 2019-06-18 | 2023-08-18 | 杭州太铭生物科技有限公司 | 外周血红细胞微核dna及其应用 |
WO2021190124A1 (zh) * | 2020-03-23 | 2021-09-30 | 南京梅傲红清生物科技有限公司 | 红细胞核酸在鉴定肿瘤的突变类型中的应用 |
Also Published As
Publication number | Publication date |
---|---|
EP2593787A2 (en) | 2013-05-22 |
MX2013000606A (es) | 2013-06-28 |
US10174364B2 (en) | 2019-01-08 |
SG187101A1 (en) | 2013-02-28 |
WO2012008839A2 (en) | 2012-01-19 |
US20130196873A1 (en) | 2013-08-01 |
HK1186767A1 (zh) | 2014-03-21 |
CA2805586C (en) | 2020-09-01 |
JP2017018099A (ja) | 2017-01-26 |
CN103168235B (zh) | 2016-01-13 |
BR112013001136B1 (pt) | 2020-12-15 |
EP2593787B1 (en) | 2018-07-04 |
WO2012008839A9 (en) | 2012-05-03 |
AU2011277178A2 (en) | 2013-02-07 |
JP6171057B2 (ja) | 2017-07-26 |
MX351242B (es) | 2017-10-05 |
JP6076901B2 (ja) | 2017-02-15 |
JP2013534429A (ja) | 2013-09-05 |
CA2805586A1 (en) | 2012-01-19 |
WO2012008839A3 (en) | 2012-03-01 |
AU2011277178B2 (en) | 2016-10-20 |
AU2011277178A1 (en) | 2013-01-31 |
BR112013001136A2 (pt) | 2016-07-05 |
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