CN103156979A - Beverage-removing and whitening medicine - Google Patents

Beverage-removing and whitening medicine Download PDF

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Publication number
CN103156979A
CN103156979A CN2013100655850A CN201310065585A CN103156979A CN 103156979 A CN103156979 A CN 103156979A CN 2013100655850 A CN2013100655850 A CN 2013100655850A CN 201310065585 A CN201310065585 A CN 201310065585A CN 103156979 A CN103156979 A CN 103156979A
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parts
radix
medicine
poria
beverage
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CN103156979B (en
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厉君
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YUNNAN JUNCHOU PHARMACEUTICAL CO Ltd
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YUNNAN JUNCHOU PHARMACEUTICAL CO Ltd
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Abstract

The invention provides a beverage-removing and whitening medicine. By mass, the beverage-removing and whitening medicine comprises 10-20 parts of Chinese angelica, 9-15 parts of white paeony roots, 12-22 parts of Chinese yam, 12-22 parts of poria cocos, 9-15 parts of safflower, 9-15 parts of peach seeds, 9-15 parts of roots of Chinese thorowax, 9-15 parts of moutan bark, 24-34 parts of roots of rehmannia, 12-24 parts of pulps of dogwood fruit, 9-15 parts of rhizoma alismatis and 15-25 parts of lithospermum. The beverage-removing and whitening medicine has functions of soothing liver and nourishing yin and enriching blood and dispersing blood stasis, and is used for depression of hepatic qi, swelling pain of chest and hypochondrium, dizziness, appetite decrease, irregular menstruation, breast distending pain and pigment diseases including pigmentation such as chloasma on face and freckles. The beverage-removing and whitening medicine has the significant effects of being fast in recovery, low in the recurrence rate and high in safety, free of side effects and the like, and is low in cost and easy and convenient to prepare.

Description

A kind of dispelling speckles and whitening face medicine
  
Technical field
The present invention relates to a kind of Chinese medicine composition---the dispelling speckles and whitening face medicine belongs to biological technical field.
Background technology
Liver controlling conveyance and dispersion has the function of turnover QI and blood, and natural disposition just is contrary to, and dislikes the change of depression, and the stimulation of any feelings will all can cause irritability strongly fragrant, and catharsis is not normal and not smooth, the light stagnation of QI, even QI rising in reverse order, and stagnation of QI QI rising in reverse order can cause blood stasis and blood oozing from the body openings or subcuta neous tissue.Treatment is take suppressing hyperactive liver for descending adverse qi as main.Three blood stasis, irritability stasis can cause blood stasis.Difficult Classic is said: " liver is long-pending, and name is said lump at the left hypochondrium, under left flank, as multiple cup, cephalopodium is arranged ... "." have between skin thread red trace person, hematoma is also " that Zhu Danxi mentions, be all say cause the syndrome of the stasis of blood because of the stagnation of QI.Common sign such as hepatosplenomegaly, spider angiomas etc. in hepatopathy are all the results of blood stasis, and treatment is just often take blood circulation promoting and blood stasis dispelling as main.
And modern society, people often because of work and life stress cause depression of liver-QI, the long-term stagnation of QI cause the stasis of blood and with congestion, hemorrhage, menoxenia, dysmenorrhea, depression, have a dizzy spell, the symptoms such as the tired power of body, vomiting, insomnia and dreamful sleep, irritability, appetite are poor, distending pain in the chest and hypochondrium, bring inconvenience for life, work.
Summary of the invention
Cause for solving the stagnation of QI uncomfortable that the stasis of blood brings, the invention provides a kind of dispelling speckles and whitening face medicine.
The invention provides a kind of like this dispelling speckles and whitening face medicine, it is characterized in that being formed by the component of following mass parts:
10~20 parts of Radix Angelicae Sinensis
9~15 parts of the Radix Paeoniae Albas
12~22 parts of Rhizoma Dioscoreaes
12~22 parts, Poria
9~15 parts, Flos Carthami
9~15 parts, Semen Persicae
9~15 parts of Radix Bupleuri
9~15 parts of Cortex Moutans
24~34 parts, the Radix Rehmanniae
12~24 parts of Fructus Corni
9~15 parts of Rhizoma Alismatis
15~25 parts of Radix Arnebiae (Radix Lithospermi)s.
Wherein, the nature and flavor of Radix Angelicae Sinensis: warm in nature, sweet in the mouth, suffering; Return liver, the heart, spleen channel; Cure mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.The nature and flavor of the Radix Paeoniae Alba: picric acid is cool; Enter liver, spleen channel; Cure mainly: nourishing blood for regulating menstruation, easing the affected liver to relieve pain, astringing YIN to stop sweating, suppressing liver-YANG.The nature and flavor of Rhizoma Dioscoreae: sweet, flat; Return spleen, lung, kidney channel; Cure mainly: spleen reinforcing nourishing the stomach, the excessive lung that promotes the production of body fluid, the kidney invigorating arresting seminal emission.The nature and flavor of Poria: sweet, light, flat; GUIXIN warp, lung meridian, spleen channel, kidney channel; Cure mainly: promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.The nature and flavor of Flos Carthami: warm in nature, acrid in the mouth, GUIXIN, Liver Channel; Cure mainly: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.The nature and flavor of Semen Persicae: hardship, sweet, flat; GUIXIN, liver, large intestine channel; Cure mainly: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.The nature and flavor of Radix Bupleuri: warm in nature, acrid in the mouth; Enter liver, spleen, bladder three warps; Cure mainly: induce sweat, dispel the wind, victory is wet.The nature and flavor of Cortex Moutan: cold in nature, bitter in the mouth, cool, be slightly cold; GUIXIN, liver, kidney channel; Cure mainly: clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.The nature and flavor of the Radix Rehmanniae: sweet, cold; GUIXIN, liver, kidney channel; Cure mainly: clearing away heat and cooling blood, yin nourishing is promoted the production of body fluid.The nature and flavor of Fructus Corni: acid, puckery, tepor; Return liver, kidney channel; Cure mainly: liver and kidney tonifying, arresting collape syndrome by astringents.The nature and flavor of Rhizoma Alismatis: sweet, light, cold; Return kidney, urinary bladder channel; Cure mainly: promoting diuresis to eliminate damp pathogen, expel the heat-evil, change the candle blood fat reducing.The nature and flavor of Radix Arnebiae (Radix Lithospermi): sweet, salty, cold; GUIXIN, Liver Channel; Cure mainly: clearing away heat and cooling blood, promoting blood circulation and detoxication, rash speckle removing, coordinating the actions of various ingredients in a prescription.
Each composition of the present invention is the commercially available prod.
The invention provides the pharmacological action of medicine: Radix Angelicae Sinensis has the merit of enriching blood and invigorating blood circulation; The Radix Paeoniae Alba has the effect of nourishing blood to suppress the hyperactive liver; Poria has the effect of promoting diuresis to eliminate damp pathogen, mind tranquilizing and the heart calming; Flos Carthami has the merit of the latus rectum of invigorating blood circulation, eliminating stasis to stop pain; Radix Bupleuri has the effect of inducing sweat, dispeling the wind; Cortex Moutan has the merit of clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling; The Radix Rehmanniae has the effect of clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting.
Dispelling speckles and whitening face medicine of the present invention makes through following method:
(1) get the raw materials ready by following mass parts:
10~20 parts of Radix Angelicae Sinensis
9~15 parts of the Radix Paeoniae Albas
12~22 parts of Rhizoma Dioscoreaes
12~22 parts, Poria
9~15 parts, Flos Carthami
9~15 parts, Semen Persicae
9~15 parts of Radix Bupleuri
9~15 parts of Cortex Moutans
24~34 parts, the Radix Rehmanniae
12~24 parts of Fructus Corni
9~15 parts of Rhizoma Alismatis
15~25 parts of Radix Arnebiae (Radix Lithospermi)s;
(2) Poria of step (1), Radix Arnebiae (Radix Lithospermi) are cleaned after, drying and crushing, screening (crossing 80~300 orders) gets fine powder, and is standby; Be 1 ︰ 4~8 with all the other ten flavor medical materials by the solid-liquid mass ratio, decoct with water three times, the each decoction 1~3 hour, cross the leaching supernatant, the relative density when merging three filtrates and being condensed into 50 ℃ is 1.35~1.40 thick paste, drying, pulverize, with above-mentioned fine powder mixing, add appropriate pharmaceutic adjuvant, make according to a conventional method the oral formulations of pharmaceutically accepting.
Dispelling speckles and whitening face medicine of the present invention makes through following method:
(1) get the raw materials ready by following mass parts:
10~20 parts of Radix Angelicae Sinensis
9~15 parts of the Radix Paeoniae Albas
12~22 parts of Rhizoma Dioscoreaes
12~22 parts, Poria
9~15 parts, Flos Carthami
9~15 parts, Semen Persicae
9~15 parts of Radix Bupleuri
9~15 parts of Cortex Moutans
24~34 parts, the Radix Rehmanniae
12~24 parts of Fructus Corni
9~15 parts of Rhizoma Alismatis
15~25 parts of Radix Arnebiae (Radix Lithospermi)s;
(2) with the medicine of respectively distinguishing the flavor of of step (1), after carrying out clean routinely, drying, be ground into fine powder, add appropriate pharmaceutic adjuvant, make according to a conventional method the oral formulations of pharmaceutically accepting, perhaps directly make according to a conventional method the oral formulations of pharmaceutically accepting.
Described pharmaceutic adjuvant is the conventional pharmaceutic adjuvants such as starch, magnesium stearate, Mel.
The described oral formulations of pharmaceutically accepting is: tablet, decoction, capsule, soft capsule, granule, pill, oral liquid.
The effect that the present invention possesses and advantage: the dispelling speckles and whitening face medicine that adopts such scheme to obtain has the soothing liver-QI yin nourishing, an effect of the blood stasis dispelling of enriching blood; Be used for depression of liver-QI, distending pain in the chest and hypochondrium is had a dizzy spell, loss of appetite, menoxenia, distending pain of the breast, face chloasma, the calm pigment disease of the pigments such as freckle and having is recovered the significant curative effect such as fast, that relapse rate is low, safe, have no side effect, and cost is low, and is simple for production.
The specific embodiment
Further illustrate content of the present invention below in conjunction with embodiment, but protection scope of the present invention is not limited in these embodiment.
Embodiment 1
(1) by following mass parts feeding:
10 parts of Radix Angelicae Sinensis, 15 parts of the Radix Paeoniae Albas, 12 parts of Rhizoma Dioscoreaes, 22 parts, Poria, 9 parts, Flos Carthami, 15 parts, Semen Persicae, 9 parts of Radix Bupleuri, 15 parts of Cortex Moutans, 24 parts, the Radix Rehmanniae, 24 parts of Fructus Corni, 9 parts of Rhizoma Alismatis, 25 parts of Radix Arnebiae (Radix Lithospermi)s;
(2) Poria in step (1), Radix Arnebiae (Radix Lithospermi) are cleaned after, drying is pulverized, and crosses 80 mesh sieves, gets fine powder, and is standby; Be 1 ︰ 4 with all the other ten flavor medical materials by the solid-liquid mass ratio, decoct with water three times, each 1 hour, get supernatant, the relative density when merging three filtrates and being condensed into 50 ℃ is 1.35~1.40 thick paste, drying, pulverize, then with above-mentioned fine powder mixing, add appropriate amount of starch, make tablet by conventional method of the prior art.
Contain the Radix Paeoniae Alba in every with peoniflorin (C 23H 28O 11) meter, must not be less than 1.50mg.
Embodiment 2
(1) by following mass parts feeding:
20 parts of Radix Angelicae Sinensis, 9 parts of the Radix Paeoniae Albas, 22 parts of Rhizoma Dioscoreaes, 12 parts, Poria, 15 parts, Flos Carthami, 9 parts, Semen Persicae, 15 parts of Radix Bupleuri, 9 parts of Cortex Moutans, 34 parts, the Radix Rehmanniae, 12 parts of Fructus Corni, 15 parts of Rhizoma Alismatis, 15 parts of Radix Arnebiae (Radix Lithospermi)s;
(2) with step (1) with the clean system of the Poria in step (1), Radix Arnebiae (Radix Lithospermi) after, drying is pulverized, and crosses 300 mesh sieves, gets fine powder, and is standby; Be 1 ︰ 6 with all the other ten flavor medical materials by the solid-liquid mass ratio, decoct with water three times, each 2 hours, get supernatant, the relative density when merging three filtrates and being concentrated into 50 ℃ is 1.35~1.40 thick paste, drying, pulverize, then with above-mentioned fine powder mixing, add appropriate magnesium stearate, make electuary by conventional method of the prior art.
Embodiment 3
(1) by following mass parts feeding:
15 parts of Radix Angelicae Sinensis, 12 parts of the Radix Paeoniae Albas, 18 parts of Rhizoma Dioscoreaes, 17 parts, Poria, 12 parts, Flos Carthami, 13 parts, Semen Persicae, 12 parts of Radix Bupleuri, 13 parts of Cortex Moutans, 29 parts, the Radix Rehmanniae, 18 parts of Fructus Corni, 12 parts of Rhizoma Alismatis, 20 parts of Radix Arnebiae (Radix Lithospermi)s;
(2) with step (1) with the clean system of the Poria in step (1), Radix Arnebiae (Radix Lithospermi) after, drying is pulverized, and crosses 200 mesh sieves, gets fine powder, and is standby; Be 1 ︰ 8 with all the other ten flavor medical materials by the solid-liquid mass ratio, decoct with water each 3 hours three times, get supernatant, the relative density when merging three filtrates and being condensed into 50 ℃ is 1.40 thick paste, drying, pulverize then and above-mentioned fine powder mixing, directly make capsule by conventional method of the prior art.
Embodiment 4
(1) by following mass parts feeding:
20 parts of Radix Angelicae Sinensis, 15 parts of the Radix Paeoniae Albas, 22 parts of Rhizoma Dioscoreaes, 22 parts, Poria, 15 parts, Flos Carthami, 15 parts, Semen Persicae, 15 parts of Radix Bupleuri, 15 parts of Cortex Moutans, 24 parts, the Radix Rehmanniae, 24 parts of Fructus Corni, 9 parts of Rhizoma Alismatis, 15 parts of Radix Arnebiae (Radix Lithospermi)s;
(2) with the medicine of respectively distinguishing the flavor of of step (1), after carrying out clean routinely, drying is ground into fine powder, adds proper honey, makes according to a conventional method pill.
Pharmacology's toxicologic study of the Chinese medicine composition of dispelling speckles and whitening face medicine provided by the invention:
When giving rat with 20g/kg, 10g/kg, the amount of 5g/kg, after gavaging continuously 90 days, in rat general activity, body weight, blood hemoglobin, leukocyte, erythrocyte, platelet, leukocyte differential count, blood, GPT, GOT, BUN, G are all without abnormal, with normal saline group there was no significant difference, its numerical value is all in normal range, the main organs such as rats'liver, spleen, lung, kidney, intestinal, brain, testis, ovary are also had no adverse effects, i.e. the Chinese medicine composition clinical practice of dispelling speckles and whitening face medicine safely, have no side effect.
Get above-described embodiment 1 gained dispelling speckles and whitening face medicine, be used for following clinical treatment:
One, treatment target
The menoxenia, distending pain of the breast, distending pain in the chest and hypochondrium 300 examples that cause because of liver qi stagnation type, and with have a dizzy spell, inappetence, depression of liver-QI, face chloasma, the calm pigment disease symptoms of the pigments such as freckle, be divided at random treatment group and matched group each 150 examples, wherein chloasma 50 examples, freckle 50 examples, pigmentation 50 examples.
Two, instructions of taking
Treatment group is oral, each 2~4,3 times on the one, serve on 21.
Matched group is taken conventional soothing liver-QI medicine routinely, serve on 21.
Three, result:
dispelling speckles and whitening face medicine provided by the invention, the effective percentage of the menoxenia that depression of liver-QI is caused reaches 96%, the effective percentage of distending pain of the breast reaches 93%, the effective percentage of distending pain in the chest and hypochondrium reaches 89%, the effective percentage of face chloasma reaches 95%, the effective percentage of face freckle reaches 91%, the Pigmented effective percentage of face reaches 90%, and the effective percentage of the menoxenia that matched group causes depression of liver-QI only reaches 60%, the effective percentage of distending pain of the breast reaches 50%, the effective percentage of distending pain in the chest and hypochondrium reaches 56%, the effective percentage of face chloasma reaches, 61%, the effective percentage of face freckle reaches 52%, the Pigmented effective percentage of face reaches 55%.
Four, conclusion
The Chinese medicine composition of dispelling speckles and whitening face medicine provided by the invention is by HERBA BUPLEURI, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Rhizoma Dioscoreae, Poria, Flos Carthami, Semen Persicae, Radix Bupleuri, Cortex Moutan, the Radix Rehmanniae, Fructus Corni, Rhizoma Alismatis, Radix Arnebiae (Radix Lithospermi).The compound preparation for preparing and get, to the menoxenia that liver qi stagnation type causes, distending pain in the chest and hypochondrium, significant curative effect is arranged, can improve cerebral tissue, the impaired power of cardiac muscle to anoxia, suppress in addition thrombotic effect in experimental animals, its effect of menoxenia is better than matched group.
the Chinese medicine composition of this dispelling speckles and whitening face medicine is according to Yi nationality of Yunnan traditional medicine document " the sorrow jail is herbal ", on the basis of traditional Chinese medical science ancient prescription (Song " formulary of peaceful benevolent dispensary "), in conjunction with Ailaoshan mountain area Yi nationality, distributed over Yunnan, Sichuan and Guizhou folk medicine experience, the pure natural ethnic drug that develops through scientific composition, through over thousands of routine clinical verification, this Chinese medicine composition is the good medicine of regulating women's endocrine, has the soothing liver-QI yin nourishing, the enrich blood effect of blood stasis dispelling, for depression of liver-QI, distending pain in the chest and hypochondrium, have a dizzy spell, loss of appetite, menoxenia, distending pain of the breast, the face chloasma, the calm pigment disease of the pigments such as freckle has significant curative effect, the good medicine for the treatment of disease.
The advantage such as effective in cure good, the application safety of the Chinese medicine composition of this dispelling speckles and whitening face medicine, toxic and side effects are little, prepared constant product quality, easy to use, be more suitable in clinical application.

Claims (3)

1. dispelling speckles and whitening face medicine is characterized in that being comprised of the component of following mass parts:
10~20 parts of Radix Angelicae Sinensis
9~15 parts of the Radix Paeoniae Albas
12~22 parts of Rhizoma Dioscoreaes
12~22 parts, Poria
9~15 parts, Flos Carthami
9~15 parts, Semen Persicae
9~15 parts of Radix Bupleuri
9~15 parts of Cortex Moutans
24~34 parts, the Radix Rehmanniae
12~24 parts of Fructus Corni
9~15 parts of Rhizoma Alismatis
15~25 parts of Radix Arnebiae (Radix Lithospermi)s.
2. prepare the method for dispelling speckles and whitening face medicine as claimed in claim 1, it is characterized in that through following each step:
(1) get the raw materials ready by following mass parts:
10~20 parts of Radix Angelicae Sinensis
9~15 parts of the Radix Paeoniae Albas
12~22 parts of Rhizoma Dioscoreaes
12~22 parts, Poria
9~15 parts, Flos Carthami
9~15 parts, Semen Persicae
9~15 parts of Radix Bupleuri
9~15 parts of Cortex Moutans
24~34 parts, the Radix Rehmanniae
12~24 parts of Fructus Corni
9~15 parts of Rhizoma Alismatis
15~25 parts of Radix Arnebiae (Radix Lithospermi)s;
(2) Poria of step (1), Radix Arnebiae (Radix Lithospermi) are cleaned after, drying and crushing, screening (crossing 80~300 orders) gets fine powder, and is standby; Be 1 ︰ 4~8 with all the other ten flavor medical materials by the solid-liquid mass ratio, decoct with water three times, the each decoction 1~3 hour, cross the leaching supernatant, the relative density when merging three filtrates and being condensed into 50 ℃ is 1.35~1.40 thick paste, drying, pulverize, with above-mentioned fine powder mixing, add appropriate pharmaceutic adjuvant, make according to a conventional method the oral formulations of pharmaceutically accepting.
3. prepare the method for dispelling speckles and whitening face medicine as claimed in claim 1, it is characterized in that through following each step:
(1) get the raw materials ready by following mass parts:
10~20 parts of Radix Angelicae Sinensis
9~15 parts of the Radix Paeoniae Albas
12~22 parts of Rhizoma Dioscoreaes
12~22 parts, Poria
9~15 parts, Flos Carthami
9~15 parts, Semen Persicae
9~15 parts of Radix Bupleuri
9~15 parts of Cortex Moutans
24~34 parts, the Radix Rehmanniae
12~24 parts of Fructus Corni
9~15 parts of Rhizoma Alismatis
15~25 parts of Radix Arnebiae (Radix Lithospermi)s;
(2) with the medicine of respectively distinguishing the flavor of of step (1), after carrying out clean routinely, drying, be ground into fine powder, add appropriate pharmaceutic adjuvant, make according to a conventional method the oral formulations of pharmaceutically accepting, perhaps directly make according to a conventional method the oral formulations of pharmaceutically accepting.
CN201310065585.0A 2013-03-01 2013-03-01 A kind of dispelling speckles and whitening face medicine Active CN103156979B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107137474A (en) * 2017-06-09 2017-09-08 魏旭東 A kind of freckle removal traditional Chinese medicinal composition

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101934052A (en) * 2010-09-04 2011-01-05 魏玮 Medicament for treating facial chloasma and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101934052A (en) * 2010-09-04 2011-01-05 魏玮 Medicament for treating facial chloasma and preparation method thereof

Non-Patent Citations (2)

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Title
南京中医药大学: "红花等", 《中药大辞典》, 31 March 2006 (2006-03-31), pages 1378 *
石本玉等: "中西医结合治疗黄褐斑", 《中华皮肤科杂志》, vol. 25, no. 6, 15 December 1992 (1992-12-15), pages 399 - 400 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107137474A (en) * 2017-06-09 2017-09-08 魏旭東 A kind of freckle removal traditional Chinese medicinal composition

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