CN103156070A - Choline chloride crystal - Google Patents
Choline chloride crystal Download PDFInfo
- Publication number
- CN103156070A CN103156070A CN2011104268326A CN201110426832A CN103156070A CN 103156070 A CN103156070 A CN 103156070A CN 2011104268326 A CN2011104268326 A CN 2011104268326A CN 201110426832 A CN201110426832 A CN 201110426832A CN 103156070 A CN103156070 A CN 103156070A
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- Prior art keywords
- choline chloride
- solution
- dressing
- chloride crystal
- ethyl cellulose
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to a choline chloride crystal. The choline chloride crystal contains the following active ingredients: 85%-95% of choline chloride particles, 1%-5% of inner-layer coatings, 1%-5% of additional-layer coatings and 1%-5% of outer-layer coatings. The choline chloride crystal has good moisture-proof effects. The slow-release purpose is achieved in a rumen, and absorption of choline chloride by small intestines is improved. The choline chloride crystal can serve as daily ration choline addition of ruminants such as cattle and sheep. Growth and absorption of animals are promoted, and the mortality of the animals is lowered.
Description
Technical field
The present invention relates to a kind of feed addictive, especially the Choline Chloride crystal.
Background technology
Choline Chloride is a kind of of Cobastab, and the fat metabolism that can promote liver, kidney is also one of synthetic required methyl source of methionine in body, and animal lacks choline can cause fatty liver, poor growth, and laying rate reduces, and death such as increases at the phenomenon.
Be widely used in Choline Chloride in the nursing of various nonruminants as animal feed additive, but due to the degradation of microorganism to Choline Chloride in the stomach of ruminant stomach animal, the application of Choline Chloride on the ruminant stomach animal is restricted, present Choline Chloride is pulvis or aqua mostly, in the time of in entering stomach of ruminants, most of can the degraded by rumen microorganism only has seldom a part to enter small intestine and is absorbed, and caused very large waste.
Summary of the invention
The purpose of this invention is to provide a kind of Choline Chloride crystal, add in the feed of ruminant, prevent that Choline Chloride is degraded in cud, can enter smoothly small intestine is absorbed, its performance of maximized performance reaches promotion growth of animal and absorption, reduces the purpose of its death rate.
The technical solution adopted for the present invention to solve the technical problems is: this Choline Chloride crystal contains effective ingredient Choline Chloride particle 85%～95%, and internal layer coating 1～5%, extra play dressing 1%～5%, outer dressing 1%～5%.
Described internal layer coating is take acrylic resin TV as raw material, and the extra play dressing is take ethyl cellulose as raw material, and outer dressing is take shitosan as raw material.
Described Choline Chloride particle is 16～40 orders.
Its preparation method is: acrylic resin IV is dissolved in makes acrylic resin IV solution for standby in 95% alcohol, ethyl cellulose is dissolved in to make ethyl cellulose solution in 95% alcohol standby, chitosan solution is dissolved in to make chitosan solution in 4% acetic acid solution standby; The Choline Chloride particle is sent into fluid bed, make it be the fluidisation attitude, then respectively aforesaid propylene acid resin IV solution, ethyl cellulose solution and chitosan solution are delivered to fluid bed through peristaltic pump, evenly be sprayed on successively the Choline Chloride particle surface as internal layer coating, additional dressing and outer dressing, make after drying the Choline Chloride crystal with dressing.
The invention has the beneficial effects as follows: this Choline Chloride crystal has moisture effect preferably, reach the purpose of slowly-releasing in cud, increase small intestine to the absorption of choline, the dietary choline that can be used as the ruminants such as ox, sheep adds, promote growth and the absorption of animal, reduce its death rate.
The specific embodiment
The invention will be further described below in conjunction with embodiment.
To prepare 1000 kilograms of Choline Chloride crystal as example.
Embodiment 1
880 kilograms of Choline Chloride particles, acrylic resin TV40 kilogram, 40 kilograms of ethyl celluloses, 40 kilograms of shitosans.
Its preparation method is: acrylic resin IV is dissolved in makes acrylic resin IV solution for standby in 95% alcohol, ethyl cellulose is dissolved in to make ethyl cellulose solution in 95% alcohol standby, chitosan solution is dissolved in to make chitosan solution in 4% acetic acid solution standby; The Choline Chloride particle is sent into fluid bed, make it be the fluidisation attitude, then respectively aforesaid propylene acid resin IV solution, ethyl cellulose solution and chitosan solution are delivered to fluid bed through peristaltic pump, evenly be sprayed on successively the Choline Chloride particle surface as internal layer coating, additional dressing and outer dressing, make after drying the Choline Chloride crystal with dressing.
Embodiment 2
900 kilograms of Choline Chloride particles, acrylic resin TV30 kilogram, 30 kilograms of ethyl celluloses, 40 kilograms of shitosans.
Its preparation method is with embodiment 1.
Claims (4)
1. Choline Chloride crystal is characterized in that: contain effective ingredient Choline Chloride particle 85%～95%, and internal layer coating 1～5%, extra play dressing 1%～5%, outer dressing 1%～5%.
2. according to claim 1, a kind of Choline Chloride crystal is characterized in that: described internal layer coating is take acrylic resin TV as raw material, and the extra play dressing is take ethyl cellulose as raw material, and outer dressing is take shitosan as raw material.
3. according to claim 1, a kind of Choline Chloride crystal is characterized in that: described Choline Chloride particle is 16～40 orders.
4. according to claim 1,2 and 3 is described, a kind of Choline Chloride crystal, it is characterized in that: its preparation method is: acrylic resin IV is dissolved in makes acrylic resin IV solution for standby in 95% alcohol, ethyl cellulose is dissolved in to make ethyl cellulose solution in 95% alcohol standby, chitosan solution is dissolved in to make chitosan solution in 4% acetic acid solution standby; The Choline Chloride particle is sent into fluid bed, make it be the fluidisation attitude, then respectively aforesaid propylene acid resin IV solution, ethyl cellulose solution and chitosan solution are delivered to fluid bed through peristaltic pump, evenly be sprayed on successively the Choline Chloride particle surface as internal layer coating, additional dressing and outer dressing, make after drying the Choline Chloride crystal with dressing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011104268326A CN103156070A (en) | 2011-12-19 | 2011-12-19 | Choline chloride crystal |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011104268326A CN103156070A (en) | 2011-12-19 | 2011-12-19 | Choline chloride crystal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103156070A true CN103156070A (en) | 2013-06-19 |
Family
ID=48579996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011104268326A Pending CN103156070A (en) | 2011-12-19 | 2011-12-19 | Choline chloride crystal |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103156070A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1219361A (en) * | 1997-12-09 | 1999-06-16 | 江西省食品机械研究所 | Preparation technology and equipment for choline chloride powder for feed |
| CN101223914A (en) * | 2008-01-03 | 2008-07-23 | 山东天普阳光生物科技有限公司 | Artificial milk for porkets |
| CN101269051A (en) * | 2008-05-08 | 2008-09-24 | 武汉工业学院 | Rumen bypass becholine microcapsule and preparation technique |
| CN101287381A (en) * | 2005-10-12 | 2008-10-15 | 金克克国际有限公司 | Stable, durable granules with active agents |
-
2011
- 2011-12-19 CN CN2011104268326A patent/CN103156070A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1219361A (en) * | 1997-12-09 | 1999-06-16 | 江西省食品机械研究所 | Preparation technology and equipment for choline chloride powder for feed |
| CN101287381A (en) * | 2005-10-12 | 2008-10-15 | 金克克国际有限公司 | Stable, durable granules with active agents |
| CN101223914A (en) * | 2008-01-03 | 2008-07-23 | 山东天普阳光生物科技有限公司 | Artificial milk for porkets |
| CN101269051A (en) * | 2008-05-08 | 2008-09-24 | 武汉工业学院 | Rumen bypass becholine microcapsule and preparation technique |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20130619 |