CN103142834A - Blood pressure reducing Chinese medicine composition and preparation method thereof - Google Patents
Blood pressure reducing Chinese medicine composition and preparation method thereof Download PDFInfo
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- CN103142834A CN103142834A CN2012103558082A CN201210355808A CN103142834A CN 103142834 A CN103142834 A CN 103142834A CN 2012103558082 A CN2012103558082 A CN 2012103558082A CN 201210355808 A CN201210355808 A CN 201210355808A CN 103142834 A CN103142834 A CN 103142834A
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Abstract
The invention provides a blood pressure reducing Chinese medicine composition and a preparation method thereof. The composition comprises Astragalus mongholicus, in a certain weight ratio of wolfberry fruit, root of red-rooted salvia, Prunella vulgaris, Schisandra, cassia seed, Radix Ophiopogonis, honeysuckle and Ligusticum wallichii. The blood pressure reducing Chinese medicine composition provided by the invention has advantages of reasonable prescription, mild properties of the medicines, simple and feasible preparation and remarkable curative effect on the patients with hypertension.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of blood pressure lowering Chinese medicinal composition and preparation method thereof.
Background technology
Hypertension is one of disease that sickness rate is the highest in the world at present, and it is the risk factor that causes apoplexy, coronary heart disease, and the more and more rejuvenation of hypertensive age of onset in this year is treated this disease at present take Western medicine as main, and Western medicine has certain side effect mostly.The traditional Chinese medical science is thought that hypertension is many and is fallen ill because psychentonia, the negative and positive of having a liking for the Liver and kidney such as food delicious food, insobriety are in the imbalance state for a long time, clinical dialectical " hyperactivity of YANG due to deficiency of YIN, deficiency of both YIN and YANG " amphitypy of dividing substantially.
Summary of the invention
In order to address the above problem, the invention provides a kind of significantly to hyperpietic's antihypertensive effect, and the property of medicine is gentle, the Chinese hypotensor combination that side effect is little.
Another object of the present invention is to provide the preparation method of said composition.
Technical scheme of the present invention is as follows:
A kind of blood pressure lowering Chinese medicinal composition, be comprised of the Radix Astragali, Fructus Lycii, Radix Salviae Miltiorrhizae, Spica Prunellae, Fructus Schisandrae Chinensis, Semen Cassiae, Radix Ophiopogonis, Flos Lonicerae, Rhizoma Chuanxiong, the parts by weight of each several part are: Radix Astragali 40-60 part, Fructus Lycii 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Spica Prunellae 5-15 part, Fructus Schisandrae Chinensis 5-15 part, Semen Cassiae 5-10 part, Radix Ophiopogonis 5-10 part, Flos Lonicerae 5-10 part, Rhizoma Chuanxiong 5-10 part.
Especially, described a kind of blood pressure lowering Chinese medicinal composition, the parts by weight of each several part are: 50 parts of the Radixs Astragali, 15 parts of Fructus Lycii, 15 parts of Radix Salviae Miltiorrhizaes, 10 parts of Spica Prunellaes, 10 parts of Fructus Schisandrae Chinensis, 8 parts of Semen Cassiaes, 8 parts of Radix Ophiopogonis, 8 parts of Flos Loniceraes, 8 parts of Rhizoma Chuanxiongs.
A kind of method for preparing described blood pressure lowering Chinese medicinal composition, concrete steps are:
(1) take the Radix Astragali, Fructus Lycii, Radix Salviae Miltiorrhizae, Spica Prunellae, Fructus Schisandrae Chinensis, Semen Cassiae, Radix Ophiopogonis, Flos Lonicerae, the Rhizoma Chuanxiong of weight portion, mix, add the decocting that 10-15 doubly measures and boil 2-3 time, each 2-3h, merging filtrate, being evaporated to relative density is 1.15-1.20(50 ℃), get extractum;
(2) extractum is dry under 60-70 ℃, dry rear extractum is pulverized, and makes patent medicine.
Especially, the preparation method of described a kind of blood pressure lowering Chinese medicinal composition can be with the agent of patent medicine add-on type agent granulation, capsule, tablet.
Behavior, the pharmacology of the medicine that the present invention adopts and act on as follows:
The Radix Astragali: sweet, tepor is returned lung, spleen, liver, kidney channel, has benefiting QI for strengthening the superficies, arresting sweating admittedly to take off, hold in the palm the effect of skin ulcer granulation promoting, inducing diuresis to remove edema.Contain the first-class antihypertensive compositions of γ-aminobutyric acid and Radix Astragali saponin in the Radix Astragali, can effectively expand peripheral blood vessel, have hypotensive effect.
Fructus Lycii: sweet, flat, the kidney invigorating nourishing the liver, nourishing blood for improving eyesight, control soreness of waist seminal emission.The parasympathetic nervous excitation that makes central and tip is arranged, reduce blood pressure.
Radix Salviae Miltiorrhizae: hardship, be slightly cold, blood circulation promoting and blood stasis dispelling, removing heat from blood mind calming, menstruction regulating and pain relieving.Contain TANSHINONES, thread crystal formation phenols, vitamin E etc.Blood pressure lowering and Dilation of coronary artery are arranged.
Spica Prunellae: sweet, hot cold, liver heat removing eliminating stagnation, excessive rising of liver-YANG, headache are dizzy.Contain the depressor substances such as triterpene saponin, significantly lasting hypotensive effect is arranged.
Fructus Schisandrae Chinensis: temperature, acid is sweet, astringing lung-QI and relieving cough, the arresting sweating that promotes the production of body fluid, kidney calming.
Semen Cassiae: salty, flat, liver heat removing kidney tonifying, dispelling pathogenic wind for improving eyesight, hypertension and hyperlipemia.Contain emodin, emodin, chrysophanol etc.
Radix Ophiopogonis: sweet, little hardship, cool, Yin-nourishing and body fluid promoting, nourishing the lung to arrest cough, relieving restlessness clears away heart-fire.
Flos Lonicerae: sweet, cold, heat-clearing and toxic substances removing, tonify deficiency are treated wind, blood pressure lowering blood fat reducing.Contain flavonoid, inositol, ortho acid, saponin etc.
Rhizoma Chuanxiong: suffering, temperature, the gas medicine in blood, blood circulation promoting and blood stasis dispelling, wind-expelling pain-stopping.
The specific embodiment
Form by the following examples, foregoing of the present invention is described in further detail again, but the scope that this should be interpreted as this bright above-mentioned theme only limits to following example, and all technology that realizes based on foregoing of the present invention all belong to scope of the present invention.
Embodiment 1
Prescription:
8 parts of 8 parts of Rhizoma Chuanxiongs of 10 parts of Semen Cassiaes of 10 parts of Fructus Schisandrae Chinensis of 15 parts of Spica Prunellaes of 15 parts of Radix Salviae Miltiorrhizaes of 50 parts of Fructus Lycii of the Radix Astragali, 8 portions of Flos Loniceraes, 8 parts of Radix Ophiopogonis
Preparation method:
(1) take 50 parts of the Radixs Astragali, 15 parts of Fructus Lycii, 15 parts of Radix Salviae Miltiorrhizaes, 10 parts of Spica Prunellaes, 10 parts of Fructus Schisandrae Chinensis, 8 parts of Semen Cassiaes, 8 parts of Radix Ophiopogonis, 8 parts of Flos Loniceraes, 8 parts of mixing of Rhizoma Chuanxiong after, the decocting that adds 10 times of amounts boils 3 times, each 2h, merging filtrate, being evaporated to relative density is 1.15(50 ℃), get extractum;
(2) extractum is dry under 60 ℃, dry rear extractum is pulverized;
(3) add dextrin, make granule.
Embodiment 2
Prescription:
5 parts of 5 parts of Fructus Schisandrae Chinensis of 10 parts of Spica Prunellaes of 10 parts of Radix Salviae Miltiorrhizaes of 40 parts of Fructus Lycii of the Radix Astragali
5 parts of 5 parts of Rhizoma Chuanxiongs of Semen Cassiae 5 portions of Flos Loniceraes, 5 parts of Radix Ophiopogonis
Preparation method:
(1) take 40 parts of the Radixs Astragali, 10 parts of Fructus Lycii, 10 parts of Radix Salviae Miltiorrhizaes, 5 parts of Spica Prunellaes, 5 parts of Fructus Schisandrae Chinensis, 5 parts of Semen Cassiaes, 5 parts of Radix Ophiopogonis, 5 parts of Flos Loniceraes, 5 parts of mixing of Rhizoma Chuanxiong after, the decocting that adds 12 times of amounts boils 2 times, each 2h, merging filtrate, being evaporated to relative density is 1.17(50 ℃), get extractum;
(2) extractum is dry under 70 ℃, dry rear extractum is pulverized;
(3) add amylum pregelatinisatum, magnesium stearate, make tablet.
Embodiment 3
Prescription:
10 parts of 10 parts of Rhizoma Chuanxiongs of 15 parts of Semen Cassiaes of 15 parts of Fructus Schisandrae Chinensis of 20 parts of Spica Prunellaes of 20 parts of Radix Salviae Miltiorrhizaes of 60 parts of Fructus Lycii of the Radix Astragali, 10 portions of Flos Loniceraes, 10 parts of Radix Ophiopogonis
Preparation method:
(1) take 60 parts of the Radixs Astragali, 20 parts of Fructus Lycii, 20 parts of Radix Salviae Miltiorrhizaes, 15 parts of Spica Prunellaes, 15 parts of Fructus Schisandrae Chinensis, 10 parts of Semen Cassiaes, 10 parts of Radix Ophiopogonis, 10 parts of Flos Loniceraes, 10 parts of mixing of Rhizoma Chuanxiong after, the decocting that adds 15 times of amounts boils 2 times, each 2h, merging filtrate, being evaporated to relative density is 1.20(50 ℃), get extractum;
(2) extractum is dry under 70 ℃, dry rear extractum is pulverized;
(3) add dextrin, granulate, fill gets capsule.
Claims (4)
1. blood pressure lowering Chinese medicinal composition, it is characterized in that being comprised of the Radix Astragali, Fructus Lycii, Radix Salviae Miltiorrhizae, Spica Prunellae, Fructus Schisandrae Chinensis, Semen Cassiae, Radix Ophiopogonis, Flos Lonicerae, Rhizoma Chuanxiong, the parts by weight of each several part are: Radix Astragali 40-60 part, Fructus Lycii 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Spica Prunellae 5-15 part, Fructus Schisandrae Chinensis 5-15 part, Semen Cassiae 5-10 part, Radix Ophiopogonis 5-10 part, Flos Lonicerae 5-10 part, Rhizoma Chuanxiong 5-10 part.
2. a kind of blood pressure lowering Chinese medicinal composition according to claim 1, is characterized in that the parts by weight of each several part are: 50 parts of the Radixs Astragali, 15 parts of Fructus Lycii, 15 parts of Radix Salviae Miltiorrhizaes, 10 parts of Spica Prunellaes, 10 parts of Fructus Schisandrae Chinensis, 8 parts of Semen Cassiaes, 8 parts of Radix Ophiopogonis, 8 parts of Flos Loniceraes, 8 parts of Rhizoma Chuanxiongs.
3. method for preparing claim 1 or 2 described blood pressure lowering Chinese medicinal composition is characterized in that concrete steps are:
(1) take the Radix Astragali, Fructus Lycii, Radix Salviae Miltiorrhizae, Spica Prunellae, Fructus Schisandrae Chinensis, Semen Cassiae, Radix Ophiopogonis, Flos Lonicerae, Rhizoma Chuanxiong and mix after, add the decocting that 10-15 doubly measures and boil 2-3 time, each 2-3h, merging filtrate, being evaporated to relative density is 1.15-1.20(50 ℃), get extractum;
(2) extractum is dry under 60-70 ℃, dry rear extractum is pulverized, and makes patent medicine.
4. a kind of preparation method of blood pressure lowering Chinese medicinal composition as claimed in claim 3, is characterized in that the agent of patent medicine add-on type agent granulation, capsule, tablet.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012103558082A CN103142834A (en) | 2012-09-24 | 2012-09-24 | Blood pressure reducing Chinese medicine composition and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112618654A (en) * | 2021-01-06 | 2021-04-09 | 孙勇博 | Oral traditional Chinese medicine wine for treating hypertension and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102274409A (en) * | 2010-06-10 | 2011-12-14 | 张天良 | Blood pressure lowering Chinese medicinal composition |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102274409A (en) * | 2010-06-10 | 2011-12-14 | 张天良 | Blood pressure lowering Chinese medicinal composition |
Non-Patent Citations (3)
| Title |
|---|
| 刘积高等: "鞑靼黄瓜菜降低血压作用的初步研究", 《兰州大学学报(自然科学版)》, no. 01, 1960 * |
| 李泽华: "高血压病中医药防治的临床文献研究", 《北京中医药》, vol. 28, no. 08, 25 August 2009 (2009-08-25) * |
| 黄淑芳等: "高血压病的中医综合治疗", 《中国临床医生》, vol. 34, no. 10, 1 October 2006 (2006-10-01) * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112618654A (en) * | 2021-01-06 | 2021-04-09 | 孙勇博 | Oral traditional Chinese medicine wine for treating hypertension and preparation method thereof |
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Application publication date: 20130612 |