CN103142716B - 一种治疗婴儿湿疹的中药外洗剂 - Google Patents
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Abstract
本发明公开了一种治疗婴儿湿疹的中药外洗剂。婴儿湿疹祖国医学称之为奶癣，又叫胎癣；本病多因禀性不耐，皮肤娇嫩，脾胃运化失职，内有胎火湿热，外受风湿热邪所侵，二者蕴阻于肌肤而致。为此，本发明选择中药黄刺皮、龙胆草、广东金钱草、算盘子叶、千里光、白头翁、土荆皮、紫草、猪苓、鸭儿芹、雪里开，水煎制成外洗剂，经我院临床试验，总有效率为95.0％，明显优于对照组。
Description
技术领域
本发明涉及一种中药组合物，尤其涉及一种治疗婴儿湿疹的中药外洗剂。
背景技术
婴儿湿疹是皮肤科常见病和多发病，婴儿湿疹俗称奶癣，常发于1～6月的婴儿，是由多种因素引起的一种具有明显渗出倾向的皮肤炎症反应，体胖婴儿多发。它的病因复杂，形态多样，渗出明显，部位不定，皮疹可反复发作，若治疗不及时，可出现较为明显的糜烂和渗液，很容易引起继发感染，常造成患儿及家长的不安和焦虑。近年来婴幼儿湿疹发病率有逐渐上升趋势，往往缠绵不愈，反复发作。西药目前常用口服抗组胺药，外用激素类软膏治疗，虽可暂时缓解症状，但停药易复发，不易为患者家属接受。
发明内容
本发明的目的是提供一种治疗婴儿湿疹的中药外洗剂。婴儿湿疹祖国医学称之为奶癣，又叫胎癣；本病多因禀性不耐，皮肤娇嫩，脾胃运化失职，内有胎火湿热，外受风湿热邪所侵，二者蕴阻于肌肤而致。
本发明的目的是通过以下技术方案实现的，该治疗婴儿湿疹的中药外洗剂由以下重量份的中药制成：黄刺皮10-25份、龙胆草10-15份、广东金钱草7-10份、算盘子叶5-10份、千里光10-35份、白头翁7-10份、土荆皮15-20份、紫草7-10份、猪苓10 -15份、鸭儿芹15-20份、雪里开10-25份。
优选的，黄刺皮20份、龙胆草13份、广东金钱草9份、算盘子叶8份、千里光20份、白头翁8份、土荆皮18份、紫草9份、猪苓12份、鸭儿芹17份、雪里开22份。
制备方法将上述中药煎煮30min，过滤取汁50mL，滤渣再加水煎煮30min，过滤取汁50mL，两煎药汁混合共为100mL备用。
方中：黄刺皮、龙胆草、广东金钱草、算盘子叶清热燥湿，利尿通淋，泻火解毒；千里光、白头翁清热解毒，凉血止痢；土荆皮杀虫止痒；紫草凉血活血，解毒透疹；猪苓、酸水草利水渗湿；鸭儿芹消炎解毒，活血消肿；雪里开行气活血，抗菌消炎。
临床资料
1、一般资料 本组患儿均为2008年12月至2010年12月我院收治的婴幼儿湿疹患儿，共120例，随机分为治疗组和对照组，每组各60例，治疗组中男42例，女8例；年龄最小35d，最大25月；病程35d至1年。其中轻者48例，仅在颜面出现红斑、脱屑，严重者12例，周身甚至四肢也可以出现；对照组中男38例，女22例；年龄最小40d，最大20月；病程40d至11月。其中轻者46例，仅在颜面出现红斑、脱屑，严重者14例。各病例病变部位多在头面部、肩、颈、胸部，少数可累及四肢。皮肤见红斑，有脱屑，甚或有潮湿、渗出糜烂面。两组患者在年龄、病程上经统计学分析，差异无统计意义(P>0.05)，具有可比性。
2、诊断标准 符合美国皮肤学会特应性皮炎诊断标准中的必备两项指标即可诊断。即(1)瘙痒；(2)具备典型表现及年龄特征， 婴儿面、颈及肢体屈侧急性、亚急性、慢性湿疹。排除疥疮、脂溢性皮炎、接触性皮炎、银屑病、鱼鳞病等。
3、治疗方法 治疗组使用本发明所述的中药外洗剂，即取黄刺皮20g、龙胆草13g、广东金钱草9g、算盘子叶8g、千里光20g、白头翁8g、土荆皮18g、紫草9g、猪苓12g、鸭儿芹17g、雪里开22g，水煎2次，两煎药汁混合共为100mL，2日1剂，每日50mL，水温在38～42℃为宜，每天洗浴2次，每次20min；对照组给予扑尔敏0.35mg/(kg·；d)，分3次口服。外涂康肤霜(本院制剂室研制，含少量去炎松、护肤霜等成分)，每日2次。对急性期有糜烂、渗出的患儿外敷黄连素溶液(黄连素5片研成粉加500mL开水溶解，温凉后用湿毛巾外敷患处)，每日2次，每次20min；两组均2周为一个疗程。
4、疗效标准 痊愈：经2个疗程治疗后，皮损及症状消失，无反复；显效：经2个疗程治疗后，皮损及症状明显减轻；无效：经2个疗程治疗后，皮损及症状无好转。
5、治疗结果 两组治疗两个疗程后统计疗效，治疗组60例，其中痊愈40例(66.7％)，有效18例(30.0％)，无效2例(3.3％)，总有效率为95.0％；对照组60例，其中痊愈26例(43.3％)，有效22例(36.7％)，无效12例(20.0％)总有效率为80.0％；两组比较可以看出，治疗组痊愈率、总有效率明显优于对照组，两组比较具有显著性差异，具有可比性(P<0.05)。
6、不良反应 治疗组有1例外洗后皮肤发红；对照组有5例出现皮肤色素沉着，2例出现轻度毛细血管扩张。均未影响治疗，未做特 殊处理。
具体实施方式
实施例一：称取黄刺皮20g、龙胆草13g、广东金钱草9g、算盘子叶8g、千里光20g、白头翁8g、土荆皮18g、紫草9g、猪苓12g、鸭儿芹17g、雪里开22g，将上述中药煎煮30min，过滤取汁50mL，滤渣再加水煎煮30min，过滤取汁50mL，两煎药汁混合共为100mL备用。
实施例二：称取黄刺皮10g、龙胆草15g、广东金钱草10g、算盘子叶5g、千里光35g、白头翁7g、土荆皮15g、紫草7g、猪苓15g、鸭儿芹20g、雪里开10g，制备方法同实施例一。
实施例三：称取黄刺皮25g、龙胆草10g、广东金钱草7g、算盘子叶10g、千里光10g、白头翁10g、土荆皮20g、紫草10g、猪苓10g、鸭儿芹15g、雪里开25g，制备方法同实施例一。
Claims (2)
1.一种治疗婴儿湿疹的中药外洗剂，其特征在于该中药外洗剂由以下重量份的中药制成：黄刺皮10-25份、龙胆草10-15份、广东金钱草7-10份、算盘子叶5-10份、千里光10-35份、白头翁7-10份、土荆皮15-20份、紫草7-10份、猪苓10-15份、鸭儿芹15-20份、雪里开10-25份。
2.根据权利要求1所述的一种治疗婴儿湿疹的中药外洗剂，其特征在于该中药外洗剂由以下重量份的中药制成：黄刺皮20份、龙胆草13份、广东金钱草9份、算盘子叶8份、千里光20份、白头翁8份、土荆皮18份、紫草9份、猪苓12份、鸭儿芹17份、雪里开22份。
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| CN105362349A (zh) * | 2015-09-17 | 2016-03-02 | 苗传娜 | 一种治疗掌跖部湿疹的中药外洗剂及护理方法 |
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