CN103141482B - Sterilization compound containing JS399-19 and mepanipyrim - Google Patents
Sterilization compound containing JS399-19 and mepanipyrim Download PDFInfo
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- CN103141482B CN103141482B CN201310043913.7A CN201310043913A CN103141482B CN 103141482 B CN103141482 B CN 103141482B CN 201310043913 A CN201310043913 A CN 201310043913A CN 103141482 B CN103141482 B CN 103141482B
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- mepanipyrim
- cyano
- amino
- bactericidal composition
- phenylancryic acetate
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- CIFWZNRJIBNXRE-UHFFFAOYSA-N mepanipyrim Chemical compound CC#CC1=CC(C)=NC(NC=2C=CC=CC=2)=N1 CIFWZNRJIBNXRE-UHFFFAOYSA-N 0.000 title claims abstract description 33
- 239000005805 Mepanipyrim Substances 0.000 title claims abstract description 31
- 230000001954 sterilising effect Effects 0.000 title abstract description 7
- 238000004659 sterilization and disinfection Methods 0.000 title abstract description 6
- 150000001875 compounds Chemical class 0.000 title abstract description 4
- 239000000203 mixture Substances 0.000 claims abstract description 24
- 206010039509 Scab Diseases 0.000 claims abstract description 17
- 241000209140 Triticum Species 0.000 claims abstract description 17
- 235000021307 Triticum Nutrition 0.000 claims abstract description 17
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims description 26
- 230000000844 anti-bacterial effect Effects 0.000 claims description 22
- 239000003899 bactericide agent Substances 0.000 claims description 8
- 239000000843 powder Substances 0.000 claims description 7
- 238000009736 wetting Methods 0.000 claims description 7
- 208000031888 Mycoses Diseases 0.000 claims description 4
- 239000004480 active ingredient Substances 0.000 claims description 2
- 239000007900 aqueous suspension Substances 0.000 claims description 2
- 239000012752 auxiliary agent Substances 0.000 claims description 2
- 239000004562 water dispersible granule Substances 0.000 claims description 2
- 238000009472 formulation Methods 0.000 claims 2
- 230000000694 effects Effects 0.000 abstract description 10
- 201000010099 disease Diseases 0.000 abstract description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 5
- 230000001988 toxicity Effects 0.000 abstract description 3
- 231100000419 toxicity Toxicity 0.000 abstract description 3
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 238000003912 environmental pollution Methods 0.000 abstract description 2
- 206010059866 Drug resistance Diseases 0.000 abstract 1
- 229930195482 Validamycin Natural products 0.000 abstract 1
- 244000052616 bacterial pathogen Species 0.000 abstract 1
- 244000144972 livestock Species 0.000 abstract 1
- JARYYMUOCXVXNK-IMTORBKUSA-N validamycin Chemical compound N([C@H]1C[C@@H]([C@H]([C@H](O)[C@H]1O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)CO)[C@H]1C=C(CO)[C@H](O)[C@H](O)[C@H]1O JARYYMUOCXVXNK-IMTORBKUSA-N 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 description 14
- 239000003814 drug Substances 0.000 description 10
- 238000000034 method Methods 0.000 description 5
- 239000000375 suspending agent Substances 0.000 description 5
- 230000010534 mechanism of action Effects 0.000 description 4
- 244000052769 pathogen Species 0.000 description 4
- 230000001717 pathogenic effect Effects 0.000 description 4
- 240000008067 Cucumis sativus Species 0.000 description 3
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 3
- 240000007594 Oryza sativa Species 0.000 description 3
- 235000007164 Oryza sativa Nutrition 0.000 description 3
- 239000013530 defoamer Substances 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 235000009566 rice Nutrition 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- FRXSZNDVFUDTIR-UHFFFAOYSA-N 6-methoxy-1,2,3,4-tetrahydroquinoline Chemical compound N1CCCC2=CC(OC)=CC=C21 FRXSZNDVFUDTIR-UHFFFAOYSA-N 0.000 description 2
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 241000223195 Fusarium graminearum Species 0.000 description 2
- 241000233679 Peronosporaceae Species 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 235000009754 Vitis X bourquina Nutrition 0.000 description 2
- 235000012333 Vitis X labruscana Nutrition 0.000 description 2
- 240000006365 Vitis vinifera Species 0.000 description 2
- 235000014787 Vitis vinifera Nutrition 0.000 description 2
- 239000002270 dispersing agent Substances 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 239000012467 final product Substances 0.000 description 2
- 230000009036 growth inhibition Effects 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 239000000575 pesticide Substances 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 239000002562 thickening agent Substances 0.000 description 2
- 239000000080 wetting agent Substances 0.000 description 2
- HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical compound C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 description 1
- UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- 239000004382 Amylase Substances 0.000 description 1
- 102000013142 Amylases Human genes 0.000 description 1
- 108010065511 Amylases Proteins 0.000 description 1
- 241001530056 Athelia rolfsii Species 0.000 description 1
- 241000193738 Bacillus anthracis Species 0.000 description 1
- 235000002566 Capsicum Nutrition 0.000 description 1
- TWFZGCMQGLPBSX-UHFFFAOYSA-N Carbendazim Natural products C1=CC=C2NC(NC(=O)OC)=NC2=C1 TWFZGCMQGLPBSX-UHFFFAOYSA-N 0.000 description 1
- 244000241235 Citrullus lanatus Species 0.000 description 1
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 description 1
- 241000222239 Colletotrichum truncatum Species 0.000 description 1
- 239000005758 Cyprodinil Substances 0.000 description 1
- 235000016623 Fragaria vesca Nutrition 0.000 description 1
- 240000009088 Fragaria x ananassa Species 0.000 description 1
- 235000011363 Fragaria x ananassa Nutrition 0.000 description 1
- 241000223218 Fusarium Species 0.000 description 1
- 241000223221 Fusarium oxysporum Species 0.000 description 1
- 241000233732 Fusarium verticillioides Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 239000006002 Pepper Substances 0.000 description 1
- 241000233616 Phytophthora capsici Species 0.000 description 1
- 235000016761 Piper aduncum Nutrition 0.000 description 1
- 235000017804 Piper guineense Nutrition 0.000 description 1
- 244000203593 Piper nigrum Species 0.000 description 1
- 235000008184 Piper nigrum Nutrition 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 241000220324 Pyrus Species 0.000 description 1
- 241000221696 Sclerotinia sclerotiorum Species 0.000 description 1
- 240000003768 Solanum lycopersicum Species 0.000 description 1
- 241000589634 Xanthomonas Species 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 150000005005 aminopyrimidines Chemical class 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 239000002518 antifoaming agent Substances 0.000 description 1
- 229960000892 attapulgite Drugs 0.000 description 1
- 238000000498 ball milling Methods 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 229920005551 calcium lignosulfonate Polymers 0.000 description 1
- RYAGRZNBULDMBW-UHFFFAOYSA-L calcium;3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Ca+2].COC1=CC=CC(CC(CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O RYAGRZNBULDMBW-UHFFFAOYSA-L 0.000 description 1
- 239000006013 carbendazim Substances 0.000 description 1
- JNPZQRQPIHJYNM-UHFFFAOYSA-N carbendazim Chemical compound C1=C[CH]C2=NC(NC(=O)OC)=NC2=C1 JNPZQRQPIHJYNM-UHFFFAOYSA-N 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- HAORKNGNJCEJBX-UHFFFAOYSA-N cyprodinil Chemical compound N=1C(C)=CC(C2CC2)=NC=1NC1=CC=CC=C1 HAORKNGNJCEJBX-UHFFFAOYSA-N 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000012990 dithiocarbamate Substances 0.000 description 1
- 150000004659 dithiocarbamates Chemical class 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000008686 ergosterol biosynthesis Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- BSDQITJYKQHXQR-UHFFFAOYSA-N methyl prop-2-eneperoxoate Chemical class COOC(=O)C=C BSDQITJYKQHXQR-UHFFFAOYSA-N 0.000 description 1
- 239000012452 mother liquor Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 229910052625 palygorskite Inorganic materials 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 235000021017 pears Nutrition 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 150000003014 phosphoric acid esters Chemical class 0.000 description 1
- 229940051841 polyoxyethylene ether Drugs 0.000 description 1
- 229920000056 polyoxyethylene ether Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 239000004576 sand Substances 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- HIEHAIZHJZLEPQ-UHFFFAOYSA-M sodium;naphthalene-1-sulfonate Chemical class [Na+].C1=CC=C2C(S(=O)(=O)[O-])=CC=CC2=C1 HIEHAIZHJZLEPQ-UHFFFAOYSA-M 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a sterilization compound containing JS399-19 and mepanipyrim, wherein a mass ratio of the JS399-19 and the mepanipyrim is 20:1-1:20. The sterilization compound containing the JS399-19 and the mepanipyrim has a good control effect against crop fungous diseases such as a wheat scab. Due to the fact that the JS399-19 and the mepanipyrim are matched in application, a dosage can be reduced, ecological damage and environmental pollution are effectively reduced, and output and quality of crops can be improved. Due to the fact that the JS399-19 and the mepanipyrim are both low in toxicity, the sterilization composition containing the mepanipyrim and the validamycin is safe to people, livestock and beneficial organisms, and can delay drug resistance of germs to a single agent.
Description
Technical field
The invention belongs to disinfectant use in agriculture field, be specifically related to the bactericidal composition of a kind of 2-cyano-3-amino-3-phenylancryic acetate and mepanipyrim.
Background technology
2-cyano-3-amino-3-phenylancryic acetate, molecular formula is C12H12N2O2, structural formula is as follows:
Chemical name: 2-cyano group-3-aminoacrylic acid ethyl ester; its mechanism of action is novel; all not identical with various sterilization agent mechanisms of action such as benzimidazole, dithiocarbamates, ergosterol biosynthesis inhibitor, methoxy acrylates; there is the effects such as protection, treatment, interior suction, transporting, can effectively control the caused plant disease of above each series bactericidal agent resistant strain.The Fusarium graminearum of Fusarium, fusarium moniliforme, Fusarium oxysporum etc. are all had to very high biologically active, be applicable to wheat scab, banded sclerotial blight, Phytophthora capsici disease, effective control of the crop pests such as bakanae disease of rice, gray mold of cucumber, watermelon blight, the cucumber downy mildew that the false downy mildew of Cuba is caused, the paddy rice blinds rot that rice Xanthomonas causes, the microbial pepper anthracnose of capsicum anthrax, the microbial talented stalk break in Belém lattice grape seat chamber also have certain inhibitory action.
Mepanipyrim (English common name: mepanipyrim), molecular formula is C
14h
13n
3, structural formula is as follows:
Chemistry adopted name is N-(4-methyl-6-third-1-alkynyl pyrimidine-2-base) aniline, for aminopyrimidine new type bactericide, the mechanism of action is for the cell wall amylase that suppresses pathogen and produce is to thalline exocrine secretion, suppress the absorption of thalline to nutrient sources such as amino acid and glucose simultaneously, thereby hinder pathogen infringement plant.Can be used for preventing and treating the various crop fungal diseases such as scab on tomato, strawberry, cucumber and grape grey mould and apple, pears.
Summary of the invention
The present invention proposes the new type bactericide composition of a kind of 2-cyano-3-amino-3-phenylancryic acetate-containing and mepanipyrim, for preventing and treating the various crop diseases such as wheat scab.2-cyano-3-amino-3-phenylancryic acetate possesses different structure types and discrepant mechanism of action from phonetic collarium, the two is combined by a certain percentage, there is in actual use bactericidal activity high, the selection pressure that can cause pathogen when avoiding to a greater extent 2-cyano-3-amino-3-phenylancryic acetate and mepanipyrim single dose to use separately simultaneously, delaying pathogen pesticide resistance produces and develops, and dosage total in unit are is declined, economical, efficient, environmental protection.
Technical scheme of the present invention is as follows
A bactericidal composition for 2-cyano-3-amino-3-phenylancryic acetate-containing and mepanipyrim, wherein the mass ratio of 2-cyano-3-amino-3-phenylancryic acetate and mepanipyrim is 20:1～1:20.
Described bactericidal composition, the mass ratio of preferred 2-cyano-3-amino-3-phenylancryic acetate and mepanipyrim is 10:1～1:10, more preferably 10:1～5:1.
In described bactericidal composition, be added with the upper conventional bactericide auxiliary agent of agricultural and can be made into aqueous suspension agent, wetting powder, water-dispersible granules.The agricultural bactericidal agent aid adopting comprises each analog assistants such as wetting agent, dispersant, thickener, defoamer, filler, and the wetting agent of employing, dispersant can be one or more in neopelex, fourth two base sodium naphthalene sulfonates, sodium lignin sulfonate, calcium lignosulfonate, alkylphenol-polyethenoxy base ether, alkylphenol-polyethenoxy base phosphate, castor oil polyoxyethylene ether etc.; The thickener adopting can be xanthans, polyvinyl alcohol etc.; The defoamer adopting can be in phosphoric acid ester defoamer and silicone defoaming agent one or more; The filler adopting can be one or more in white carbon, kaolin, attapulgite etc.;
Described bactericidal composition, preferred, the active ingredient that 2-cyano-3-amino-3-phenylancryic acetate and mepanipyrim form accounts for 20%～60% of bactericidal composition gross mass.
The application of described bactericidal composition in preventing and treating the crop fungal diseases such as wheat scab.
By the careful analysis to 2-cyano-3-amino-3-phenylancryic acetate and the mepanipyrim mechanism of action and sterilization idiocratic, use Wadley method to carry out experimental scheme and result treatment.First measure the EC of 2-cyano-3-amino-3-phenylancryic acetate and mepanipyrim two single compounds (hereinafter to be referred as medicament)
50, according to the EC of two single medicaments
50by Wadley method, set the portfolio ratio of two medicaments, and according to Wadley synergy index SR value, determine suitable composition ratio, then by the abundant method of Sun Yun, verified.
Test objective thing is wheat scab.Test adopts colony diameter method.Get 2-cyano-3-amino-3-phenylancryic acetate, mepanipyrim mother liquor, be configured to need liquid dull and stereotyped, the about 14ml of every ware arranges without the dull and stereotyped contrast of medicine (CK) simultaneously, and every processing repeats 3 wares, repeats 3 times.At preculture colony edge, with the card punch of sterilizing, produce the mycelia piece of 5mm diameter, move on to respectively on different culture media flat board, cultivate 4d for 28 ℃, measure colony diameter (mm), by following formula, calculate growth inhibition ratio:
Mycelial growth inhibition rate is converted into and suppresses probit value (Y), drug concentration is converted into concentration logarithm (X), by concentration logarithm, be that abscissa, probit value are that ordinate is made toxicity regression straight line, try to achieve 2-cyano-3-amino-3-phenylancryic acetate and mepanipyrim single dose and the virulence regression equation of mixture to fusarium graminearum thereof, and calculate EC
50, EC
90value and correlation coefficient r value.
According to the interaction of Wadley method evaluation mixture, computing formula is as follows:
EC
50 (theoretical values)=(a+b)/(a/EC
50a+ b/EC
50b), SR=EC
50 (theoretical values)/ EC
50 (real values).
Wherein a, b are each component content ratio in mixture, the effect being mixed with the analysis of SR value.SR≤0.5, two kinds of medicaments antagonism that has been mixed; SR=0.5～1.5, two kinds of medicaments addition that has been mixed; SR >=1.5, two kinds of medicaments synergistic effect that has been mixed.
Table 1 2-cyano-3-amino-3-phenylancryic acetate and mepanipyrim single dose and mixture thereof are to wheat scab toxicity test result
From table 1, data can be analyzed and obtain, and carbendazim and mepanipyrim can suppress the growth of wheat scab mycelia while being mixed with 15:1～1:15 ratio, with 5:1 and 1:5 ratio, are mixed, and can suppress more by force the growth of wheat scab mycelia, performance synergistic effect.
The present invention has good control efficiency to crop fungal diseases such as wheat scabs, and two medicament fit applications, can reduce dosage, effectively reduce ecological disruption and environmental pollution, and can improve crop yield and quality; In the present invention, 2-cyano-3-amino-3-phenylancryic acetate and mepanipyrim all belong to the toxicity such as low, to people and animals, beneficial organism safety; Can delay the pesticide resistance of germ to single medicament.
Embodiment
Following embodiment is usingd as the explaination to the technology of the present invention content for further illustrating of content of the present invention; but flesh and blood of the present invention is not limited in described in following embodiment, those of ordinary skill in the art can and should know any simple change or replacement based on connotation of the present invention all should belong to protection domain of the presently claimed invention.
Embodiment 1
The preparation method of 60% 2-cyano-3-amino-3-phenylancryic acetate mepanipyrim suspending agent: by mass percentage.
Preparation method: according to formula, above component is weighed in proportion, add ball mill ball milling 30 minutes, filter, suction dispersion tank high speed shear is fully ground by sand mill for 3 minutes, controls solid constituent particle diameter in 2 microns, grinding stirs after finishing, and obtains suspending agent product.Every mu of 60-80g is used for preventing and treating wheat scab effect and can reaches more than 88%.
Embodiment 2
The preparation method of 48% 2-cyano-3-amino-3-phenylancryic acetate mepanipyrim suspending agent: by mass percentage.
Preparation method, with embodiment 1.Every mu of 60-80g is used for preventing and treating wheat scab effect and can reaches 76%.
Embodiment 3
The preparation method of 55% 2-cyano-3-amino-3-phenylancryic acetate mepanipyrim suspending agent: by mass percentage.
Preparation method, with embodiment 1.Every mu of 60-80g is used for preventing and treating wheat scab effect and can reaches 80%.
Embodiment 4
The preparation method of 60% 2-cyano-3-amino-3-phenylancryic acetate mepanipyrim wetting powder: by mass percentage.
Preparation method: add mixer to mix laggard row air-flow crushing by formula rate above component, stir after having pulverized, get final product to obtain wetting powder product.Every mu of 60-80g is used for preventing and treating wheat sharp eyespot effect and can reaches 86%.
Embodiment 5
The preparation method of 22% 2-cyano-3-amino-3-phenylancryic acetate mepanipyrim wetting powder: by mass percentage.
Preparation method, with embodiment 4.Every mu of 60-80g is used for preventing and treating wheat scab effect and reaches 80%.
Embodiment 6
The preparation method of 30% 2-cyano-3-amino-3-phenylancryic acetate cyprodinil wetting powder: by mass percentage.
Preparation method: add mixer to mix laggard row air-flow crushing by formula rate above component, add a small amount of purified water to stir after having pulverized, extruder grain, gets final product to obtain wetting powder product after oven dry.Every mu of 60-80g is used for preventing and treating wheat scab effect and can reaches 82%.
Embodiment 7
The preparation method of 32% 2-cyano-3-amino-3-phenylancryic acetate mepanipyrim suspending agent: by mass percentage.
Preparation method, with embodiment 1.Every mu of 60-80g is used for preventing and treating wheat scab effect and can reaches 80%.
Claims (5)
1. a bactericidal composition for 2-cyano-3-amino-3-phenylancryic acetate-containing and mepanipyrim, is characterized in that: in described bactericidal composition, the mass ratio of 2-cyano-3-amino-3-phenylancryic acetate and mepanipyrim is 5:1 or 1:5.
2. bactericidal composition according to claim 1, is characterized in that: be added with the upper conventional bactericide auxiliary agent of agricultural and make the upper acceptable bactericide formulation of agricultural.
3. bactericidal composition according to claim 2, is characterized in that: described bactericide formulation is aqueous suspension agent, wetting powder or water-dispersible granules.
4. bactericidal composition according to claim 3, is characterized in that: the active ingredient that described 2-cyano-3-amino-3-phenylancryic acetate and mepanipyrim form accounts for 20%～60% of bactericidal composition gross mass.
5. the bactericidal composition described in claim 1-4 any one can be used for preventing and treating the crop fungal disease of wheat scab.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310043913.7A CN103141482B (en) | 2013-02-04 | 2013-02-04 | Sterilization compound containing JS399-19 and mepanipyrim |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310043913.7A CN103141482B (en) | 2013-02-04 | 2013-02-04 | Sterilization compound containing JS399-19 and mepanipyrim |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103141482A CN103141482A (en) | 2013-06-12 |
| CN103141482B true CN103141482B (en) | 2014-08-27 |
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|---|---|---|---|
| CN201310043913.7A Active CN103141482B (en) | 2013-02-04 | 2013-02-04 | Sterilization compound containing JS399-19 and mepanipyrim |
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| CN103493807B (en) * | 2013-09-29 | 2015-04-08 | 江苏省绿盾植保农药实验有限公司 | Bactericide composition containing JS399-19 and zoxamide |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1559210A (en) * | 2004-02-18 | 2005-01-05 | 江苏省农药研究所有限公司 | 2-cyano-3-amino-3-ethyl phenylacrylate used for prevention and control of plant disease and elimination of pests |
| CN1623390A (en) * | 2004-10-27 | 2005-06-08 | 江苏省农药研究所有限公司 | Application of 2-cydno-3-amino-3-phenylethyl acrylate for preventing and treating patty rice bakanae disease |
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2013
- 2013-02-04 CN CN201310043913.7A patent/CN103141482B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1559210A (en) * | 2004-02-18 | 2005-01-05 | 江苏省农药研究所有限公司 | 2-cyano-3-amino-3-ethyl phenylacrylate used for prevention and control of plant disease and elimination of pests |
| CN1623390A (en) * | 2004-10-27 | 2005-06-08 | 江苏省农药研究所有限公司 | Application of 2-cydno-3-amino-3-phenylethyl acrylate for preventing and treating patty rice bakanae disease |
Non-Patent Citations (4)
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| 嘧啶胺类杀菌剂的作用机制;马忠华等;《农药科学与管理》;19970215(第01期);30-32 * |
| 新型杀菌剂――氰烯菌酯(JS399-19);郎玉成等;《世界农药》;20071025;第29卷(第05期);52-53 * |
| 郎玉成等.新型杀菌剂――氰烯菌酯(JS399-19).《世界农药》.2007,第29卷(第05期),52-53. |
| 马忠华等.嘧啶胺类杀菌剂的作用机制.《农药科学与管理》.1997,(第01期),30-32. |
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| CN103141482A (en) | 2013-06-12 |
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