CN103120751B - Traditional Chinese medicine composition for treating insomnia - Google Patents
Traditional Chinese medicine composition for treating insomnia Download PDFInfo
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- CN103120751B CN103120751B CN201310083431.4A CN201310083431A CN103120751B CN 103120751 B CN103120751 B CN 103120751B CN 201310083431 A CN201310083431 A CN 201310083431A CN 103120751 B CN103120751 B CN 103120751B
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Abstract
The invention discloses a traditional Chinese medicine composition for treating insomnia. The traditional Chinese medicine composition for treating insomnia is prepared from the following components in parts by weight of 10-30 parts of spina date seed, 10-20 parts of tuber fleeceflower stem, 10-20 parts of dried radix rehmanniae, 3-8 parts of Chinese-date, 5-15 parts of lily, 5-15 parts of cortex albiziae, 5-15 parts of calcined keel and 3-7 parts of honey-fried licorice root. The traditional Chinese medicine composition is accurate in curative effect, high in total effective rate, low in toxic and side effects, wide in formula drug source, low in price, and good in development and application prospects, and can be prepared into various drugs required for clinic treatment according to common methods of the traditional Chinese pharmacology.
Description
Technical field
The invention belongs to field of medicaments, relate to a kind of Chinese medicine composition.
Background technology
Insomnia claims again DIMS, for difficulty falling asleep, Depth of sleep or the frequency that a variety of causes causes is too short, early awakening and the length of one's sleep not enough or of poor quality etc.Traditional insomnia crowd is mainly old people.In recent years, be subject to rhythm of life raising, operating pressure or the factors such as pressure increasing of entering a higher school affect, the sickness rate of insomnia rises year by year, and increasing youngster and teenager have added the ranks of insomnia, the rejuvenation day by day of having a sleepless night.From short-term effect, insomnia can directly affect work or the study of second day, and lethargy is tired out unable, and emotional lability is absent minded.From long-term effect, easily there are anxiety, short-tempered, photis, Immune Dysfunction, digestive function and sexual hypofunction, hypomnesis etc. in the patient of long-term insomnia, easily brings out the diseases such as hypertension, coronary heart disease, apoplexy, diabetes.Owing to being absorbed in for a long time in the worry of sleep and fear, insomniac's suspicious, responsive, irritability and self-doubt that also can become, and then affect its study and work.
For sleep better, some insomniac's custom is taken sleeping pill, but take sleeping pill, easily forms dependency, and excessive use also can damage health and brain.Traditional Chinese medicine in treating insomnia has no side effect safely.The successive dynasties traditional Chinese medical science thinks, the etiology and pathogenesis of insomnia be take internal injury caused by excess of seven emotions as Etiological, and the internal organs that relate to comprise the heart, spleen, liver, gallbladder, kidney, and pathogenesis always belongs to battalion to be defended and becomes estranged, imbalance of YIN and YANG be disease, or the deficiency of YIN can not receive sun, or the excess of YANG must not enter the moon.At present existing many bibliographical informations be used for the treatment of insomnia's Chinese medicine composition, but all there is shortcoming more or less in these Chinese medicine compositions, as prescription is complicated, part prescription price of medicinal material is expensive or poisonous etc.Therefore, need how efficient, safe, the inexpensive medicine of development.
Summary of the invention
In view of this, the object of the present invention is to provide a kind of insomnia's of being used for the treatment of Chinese medicine composition, determined curative effect, total effective rate is high, and toxic and side effects is low, and prescription crude drug source is extensive, cheap.
Concrete technical scheme is as follows:
The Chinese medicine composition that is used for the treatment of insomnia, composed of the following components by weight: 10 ~ 30 parts of Semen Ziziphi Spinosaes, 10 ~ 20 parts of Caulis Polygoni Multiflori, 10 ~ 20 parts, the Radix Rehmanniae, 3 ~ 8 parts, Fructus Jujubae, 5 ~ 15 parts of Bulbus Liliies, 5 ~ 15 parts of Cortex Albiziaes, 5 ~ 15 parts of Os Draconis (calcined)s, 3 ~ 7 parts of Radix Glycyrrhizae Preparatas.
Preferably, described Chinese medicine composition is composed of the following components by weight: 10 parts of Semen Ziziphi Spinosaes, 10 parts of Caulis Polygoni Multiflori, 10 parts, the Radix Rehmanniae, 3 parts, Fructus Jujubae, 15 parts of Bulbus Liliies, 15 parts of Cortex Albiziaes, 15 parts of Os Draconis (calcined)s, 7 parts of Radix Glycyrrhizae Preparatas.
Preferably, described Chinese medicine composition is composed of the following components by weight: 30 parts of Semen Ziziphi Spinosaes, 20 parts of Caulis Polygoni Multiflori, 20 parts, the Radix Rehmanniae, 8 parts, Fructus Jujubae, 5 parts of Bulbus Liliies, 5 parts of Cortex Albiziaes, 5 parts of Os Draconis (calcined)s, 3 parts of Radix Glycyrrhizae Preparatas.
Preferred, described Chinese medicine composition is composed of the following components by weight: 20 parts of Semen Ziziphi Spinosaes, 15 parts of Caulis Polygoni Multiflori, 15 parts, the Radix Rehmanniae, 5 parts, Fructus Jujubae, 10 parts of Bulbus Liliies, 10 parts of Cortex Albiziaes, 10 parts of Os Draconis (calcined)s, 5 parts of Radix Glycyrrhizae Preparatas.
In above-mentioned prescription, Semen Ziziphi Spinosae, Caulis Polygoni Multiflori are monarch drug altogether, tranquilizing by nourishing the heart, arresting sweating, dredging collateral; The Radix Rehmanniae, Fructus Jujubae, Bulbus Lilii, Cortex Albiziae, Os Draconis (calcined) are ministerial drug altogether, clearing away heat and cooling blood, nourishing YIN and moistening the lung, invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind; Radix Glycyrrhizae Preparata is adjuvant drug, spleen reinforcing stomach function regulating, Yiqi and vein recovery.All medicines share, and play altogether tranquilizing by nourishing the heart, the effect of enriching yin boost qi.
Beneficial effect of the present invention is: Chinese medicine composition provided by the invention is treatment of insomnia patients effectively, determined curative effect, obvious effective rate is 82.5 ~ 90.0%, total effective rate is 90.0 ~ 95.0%, and toxic and side effects is low, prescription crude drug source is extensive, cheap, can make the various medicaments that clinical treatment needs that are applicable to according to the conventional method of Chinese materia medica, has good development prospect.
The specific embodiment
In order to make the object, technical solutions and advantages of the present invention clearer, below the preferred embodiments of the present invention are described in detail.
the preparation of embodiment 1, Chinese medicine composition (prescription 1) and capsule thereof
1, the composition of Chinese medicine composition (by weight): 10 parts of Semen Ziziphi Spinosaes, 10 parts of Caulis Polygoni Multiflori, 10 parts, the Radix Rehmanniae, 3 parts, Fructus Jujubae, 15 parts of Bulbus Liliies, 15 parts of Cortex Albiziaes, 15 parts of Os Draconis (calcined)s, 7 parts of Radix Glycyrrhizae Preparatas.
2, the preparation of capsule: get the composition medical material of above-mentioned Chinese medicine composition, porphyrize, crosses 80 mesh sieves respectively, then by the proportion of composing mix homogeneously of above-mentioned Chinese medicine composition, pack capsulae vacuus (every dress 2g) into, obtain capsule.
the preparation of embodiment 2, Chinese medicine composition (prescription 2) and capsule thereof
1, the composition of Chinese medicine composition (by weight): 30 parts of Semen Ziziphi Spinosaes, 20 parts of Caulis Polygoni Multiflori, 20 parts, the Radix Rehmanniae, 8 parts, Fructus Jujubae, 5 parts of Bulbus Liliies, 5 parts of Cortex Albiziaes, 5 parts of Os Draconis (calcined)s, 3 parts of Radix Glycyrrhizae Preparatas.
2, the preparation of capsule: get the composition medical material of above-mentioned Chinese medicine composition, porphyrize, crosses 80 mesh sieves respectively, then by the proportion of composing mix homogeneously of above-mentioned Chinese medicine composition, pack capsulae vacuus (every dress 2g) into, obtain capsule.
the preparation of embodiment 3, Chinese medicine composition (prescription 3) and capsule thereof
1, the composition of Chinese medicine composition (by weight): 20 parts of Semen Ziziphi Spinosaes, 15 parts of Caulis Polygoni Multiflori, 15 parts, the Radix Rehmanniae, 5 parts, Fructus Jujubae, 10 parts of Bulbus Liliies, 10 parts of Cortex Albiziaes, 10 parts of Os Draconis (calcined)s, 5 parts of Radix Glycyrrhizae Preparatas.
2, the preparation of capsule: get the composition medical material of above-mentioned Chinese medicine composition, porphyrize, crosses 80 mesh sieves respectively, then by the proportion of composing mix homogeneously of above-mentioned Chinese medicine composition, pack capsulae vacuus (every dress 2g) into, obtain capsule.
the clinical efficacy of embodiment 4, Chinese medicine composition
1, physical data
In February, 2007 ~ 2012 are accepted hyperhidrosis patient 160 examples for medical treatment year February, are divided at random treatment group 1, treatment group 2, treatment group 3 and matched group.
Treatment group 1 is totally 40 examples: 23 ~ 62 years old age, 35 years old mean age; The course of disease 86 days to 6 years, average course of disease 287 days; State of an illness patients with mild 13 examples account for 32.5%, and moderate patient's 25 examples account for 62.5%, and severe patient's 2 examples account for 5.0%.
Treatment group 2 is totally 40 examples: 16 ~ 65 years old age, 37 years old mean age; The course of disease 115 days to 5 years, average course of disease 256 days; State of an illness patients with mild 11 examples account for 27.5%, and moderate patient's 26 examples account for 65.0%, and severe patient's 3 examples account for 7.5%.
Treatment group 3 is totally 40 examples: 21 ~ 58 years old age, 31 years old mean age; The course of disease 97 days to 5 years, average course of disease 271 days; State of an illness patients with mild 12 examples account for 30.0%, and moderate patient's 27 examples account for 67.5%, and severe patient's 1 example accounts for 2.5%.
Matched group is totally 40 examples: 18 ~ 59 years old age, 33 years old mean age; The course of disease 78 days to 5 years, average course of disease 235 days; State of an illness patients with mild 10 examples account for 25.0%, and moderate patient's 27 examples account for 67.5%, and severe patient's 3 examples account for 7.5%.
On age, the course of disease, severity extent, learn by statistics relatively there was no significant difference (P>0.05) for four groups.
2, Therapeutic Method
The capsule of oral embodiment 1 preparation for the treatment of group 1, every day 2 times, takes each 2 sooner or later; The capsule of oral embodiment 2 preparations for the treatment of group 2, every day 2 times, takes each 2 sooner or later; The capsule of oral embodiment 3 preparations for the treatment of group 3, every day 2 times, takes each 2 sooner or later; The oral ANSHEN BUXIN WAN of matched group (the heavy 2g of every 15 balls), every day 3 times, each 15 balls.
3, therapeutic outcome
Refer to table 1.
The curative effect comparison of table 1 treatment of insomnia patients
| Group | n | Obvious effective rate (%) | Effective percentage (%) | Total effective rate (%) |
| Treatment group 1 | 40 | 82.5（33/40） | 7.5（3/40） | 90.0（36/40） |
| Treatment group 2 | 40 | 87.5（35/40） | 5.0（2/40） | 92.5（37/40） |
| Treatment group 3 | 40 | 90.0（36/40） | 5.0（2/40） | 95.0（38/40） |
| Matched group | 40 | 67.5（27/40） | 10.0（4/40） | 77.5（31/40） |
4, model case
Case 1: Chen, man, 23 years old.Have a sleepless night 5 years, difficulty falling asleep, dizziness, hypomnesis.The capsule of taking embodiment 1 preparation is no longer dizzy after 10 days, and insomnia makes moderate progress, and takes obviously improvement of insomnia afterwards in 40 days, and memory is also obviously recovered.
Case 2: Lee, female, 38 years old.From before 2 years, dreaminess after sleeping, after waking up, spirit is poor, and mood is irritated, and brothers' heart is easily perspired, and pale tongue with thin fur is white, thready and rolling pulse.The capsule of taking embodiment 1 preparation after 5 days symptom alleviate, take symptom convalesce after 30 days, have no recurrence.
Case 3: week certain, female, 18 years old.Learning pressure is large, and 3 wheat harvesting periods come, difficulty falling asleep, and dreaminess after sleeping, the attention of attending class daytime cannot be concentrated, and emotion is impatient.The capsule of taking embodiment 2 preparation after 10 days symptom alleviate, take insomnia after 30 days and substantially disappear.
Case 4: section certain, man, 51 years old.Have a sleepless night 2 years, difficulty is fallen asleep, dreaming often and waking easily, and headache on daytime, emotion is irritated, low, anorexia.The capsule of taking embodiment 2 preparation after 20 days symptom obviously improve, take after 50 days and be almost recovered.
Case 5: Zou, female, 40 years old.Normal insomnia in nearly 5 years or dreaming often and waking easily, anxious, easily angry, dizzy weak.The capsule of taking embodiment 3 preparation after 20 days symptom obviously alleviate, take above-mentioned symptom after 60 days and substantially disappear, more than a year recurrence.
Case 6: Deng, female, 57 years old.Have a sleepless night nearly 1 year, bad dream is diverse and confused, gradually, to sitting up all night, accompanies vexed, scorching, cardio palmus shape.Take the capsule of embodiment 3 preparations and can gradually fall asleep after 15 days, insomnia is eased, and takes above-mentioned symptom after 20 days and substantially disappears.
Finally explanation is, above embodiment is only unrestricted in order to technical scheme of the present invention to be described, although by with reference to the preferred embodiments of the present invention, invention has been described, but those of ordinary skill in the art is to be understood that, can to it, make various changes in the form and details, and not depart from the spirit and scope of the present invention that appended claims limits.
Claims (4)
1. the Chinese medicine composition that is used for the treatment of insomnia, it is characterized in that, composed of the following components by weight: 10 ~ 30 parts of Semen Ziziphi Spinosaes, 10 ~ 20 parts of Caulis Polygoni Multiflori, 10 ~ 20 parts, the Radix Rehmanniae, 3 ~ 8 parts, Fructus Jujubae, 5 ~ 15 parts of Bulbus Liliies, 5 ~ 15 parts of Cortex Albiziaes, 5 ~ 15 parts of Os Draconis (calcined)s, 3 ~ 7 parts of Radix Glycyrrhizae Preparatas.
2. Chinese medicine composition according to claim 1, is characterized in that, composed of the following components by weight: 10 parts of Semen Ziziphi Spinosaes, 10 parts of Caulis Polygoni Multiflori, 10 parts, the Radix Rehmanniae, 3 parts, Fructus Jujubae, 15 parts of Bulbus Liliies, 15 parts of Cortex Albiziaes, 15 parts of Os Draconis (calcined)s, 7 parts of Radix Glycyrrhizae Preparatas.
3. Chinese medicine composition according to claim 1, is characterized in that, composed of the following components by weight: 30 parts of Semen Ziziphi Spinosaes, 20 parts of Caulis Polygoni Multiflori, 20 parts, the Radix Rehmanniae, 8 parts, Fructus Jujubae, 5 parts of Bulbus Liliies, 5 parts of Cortex Albiziaes, 5 parts of Os Draconis (calcined)s, 3 parts of Radix Glycyrrhizae Preparatas.
4. Chinese medicine composition according to claim 1, is characterized in that, composed of the following components by weight: 20 parts of Semen Ziziphi Spinosaes, 15 parts of Caulis Polygoni Multiflori, 15 parts, the Radix Rehmanniae, 5 parts, Fructus Jujubae, 10 parts of Bulbus Liliies, 10 parts of Cortex Albiziaes, 10 parts of Os Draconis (calcined)s, 5 parts of Radix Glycyrrhizae Preparatas.
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| CN103721107A (en) * | 2014-01-16 | 2014-04-16 | 彭玉华 | Traditional Chinese medicine composition for treatment of neurasthenia |
| CN105343589A (en) * | 2015-10-31 | 2016-02-24 | 柯前程 | Medicine for treating insomnia |
| CN107137646A (en) * | 2017-06-07 | 2017-09-08 | 陈胤峰 | A kind of seedling medicine for the treatment of of insomnia patients |
| CN112089769A (en) * | 2020-08-21 | 2020-12-18 | 郑州中一堂健康管理有限公司 | Traditional Chinese medicine composition for aiding sleep, preparation method thereof and traditional Chinese medicine sleep aiding bag |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101822790A (en) * | 2010-05-07 | 2010-09-08 | 成都海旺科技有限责任公司 | Prescription for treating insomnia |
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| CN101822790A (en) * | 2010-05-07 | 2010-09-08 | 成都海旺科技有限责任公司 | Prescription for treating insomnia |
Non-Patent Citations (2)
| Title |
|---|
| 丁树栋.治失眠验方 中国中医药报社数字报刊平台.《360doc个人图书馆》.2012,治失眠验方的第5个组方，http://www.360doc.com/content/12/0203/17/8507568_183926447.shtml. |
| 治失眠验方 中国中医药报社数字报刊平台;丁树栋;《360doc个人图书馆》;20120203;治失眠验方的第5条，http://www.360doc.com/content/12/0203/17/8507568_183926447.shtml * |
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