CN103110465A - Magnesium alloy coronary support frame - Google Patents

Magnesium alloy coronary support frame Download PDF

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Publication number
CN103110465A
CN103110465A CN201210442913XA CN201210442913A CN103110465A CN 103110465 A CN103110465 A CN 103110465A CN 201210442913X A CN201210442913X A CN 201210442913XA CN 201210442913 A CN201210442913 A CN 201210442913A CN 103110465 A CN103110465 A CN 103110465A
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China
Prior art keywords
magnesium alloy
main unit
support frame
straight line
coronary artery
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CN201210442913XA
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Chinese (zh)
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CN103110465B (en
Inventor
李莉
刘二宝
李珍
郑玉峰
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JIANGYIN BAOYIDE MEDICAL TECHNOLOGY CO., LTD.
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Harbin Engineering University
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Publication of CN103110465A publication Critical patent/CN103110465A/en
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Abstract

The invention provides a magnesium alloy coronary support frame and relates to a metal coronary artery support frame. The problems that metal preparation which is not degradable of stainless steel, cobalt chrome alloy, platinum iridium alloy, chromel alloy, tantalum and the like are adopted by the prior support frame, toxic reaction is caused due to the fact that the support frame is implanted in a blood vessel as a foreign material are solved. The support frame is carved into a net shape round pipe structure by the magnesium alloy through a laser. The net shape round pipe structure is composed of a plurality of subject units and a plurality of straight line connecting bodies. Each subject unit is composed of a half circular ring, two quarters of round rings and two arcs. The two quarters of the round rings are arranged symmetrically at two ends of the half circular ring. The quarters of the round rings are connected with the half circular ring through the arcs. The plurality of the subject units are uniformly arranged along the axial direction and the circumference direction of a net pipe. Every adjacent two subject units are arranged symmetrically relative to a straight line connecting body in the plurality of the subject units arranged along the circumference direction. Arc top ends of every adjacent two half circular rings are connected with one straight line connecting body. The magnesium alloy coronary support frame is used for clinical curing coronary disease.

Description

A kind of magnesium alloy coronary artery bracket
Technical field
The present invention relates to a kind of metal coronary stent, be specifically related to a kind of magnesium alloy coronary artery bracket.
Background technology
Percutaneous Intracoronary Arterial Stenting is one of effective method for the treatment of at present coronary heart disease.For limitation or interim narrow patient are arranged through the clear and definite coronary artery of selective coronary arteriography, send into by cardiac catheter and be with standoff sacculus, carry out balloon expandable at narrow coronary artery pathological changes place and place support with the support blood vessels effect, make the restoration of blood flow at angiostenosis place normal, effectively guarantee the blood supply of cardiac muscle.
The stent types of using clinically at present is a lot, and emphasis is different, but purpose is all to improve support force, compliance, improves the spreading performance of support etc.
Patent publication No. is in the patent of invention of CN2423899Y and CN2517403Y, disclose respectively the coronary stent of a kind of coronary stent and a kind of non-homogeneous waveform configuration, the axial shortening rate after expansion is large mainly for support, the metal surface coverage rate is large for above-mentioned two supports, the axial poor problem of flexibility.Though above-mentioned two supports have the effect that the metal surface coverage rate is low, the axial shortening rate is little, axial flexibility is good.Yet their waveform all exists the large holding power of radial deformation poor circumferentially asymmetric; In addition, the material of above-mentioned two supports is rustless steel.
Patent publication No. is in the patent of invention of CN2885177Y, discloses a kind of high radial holding power, axial soft, low section rate coronary stent, and radial support power is high although this support has, the characteristics of axial softness, low section rate.But, because the material of this support is rustless steel or cochrome.
At present, the support of extensive use generally adopts the nondegradable preparation of metals such as rustless steel, cochrome, platinumiridio, Nitinol, tantalum to form clinically, these metal rack stable chemical natures, owing to not containing above-mentioned element in human body, support is as in the long-term implantable intravascular of foreign body, incompatible with human body, can cause toxic reaction.
Summary of the invention
The objective of the invention is generally to adopt the nondegradable preparation of metals such as rustless steel, cochrome, platinumiridio, Nitinol, tantalum to form for solving the existing support of using clinically, support is as in the long-term implantable intravascular of foreign body, incompatible with human body, can cause the problem of toxic reaction, and a kind of magnesium alloy coronary artery bracket is provided.
The present invention is achieved through the following technical solutions:
support of the present invention reticulates circular tube structure by magnesium alloy through laser engraving, described netty circular tube structure is comprised of several main unit and several straight line connectors, each main unit is by a semicircular ring, two quadrant rings and two circular arcs form, two quadrant rings are symmetricly set on the two ends of semicircular ring, and be connected by circular arc between quadrant ring and semicircular ring, circular arc recessed to the center towards semicircular ring, several main unit have two to four along the axially-aligned of webmaster, several main unit have eight to 18 along the circumferential arrangement of webmaster, in several main unit of circumferential arrangement, every adjacent two main unit are symmetrical arranged with a straight line connector, straight line connector of circular arc top connection of every adjacent two semicircular ring.
The present invention compared with prior art has following effect:
1, coronary artery bracket of the present invention is to form tubular structure by magnesium alloy through laser engraving, and magnesium alloy is degradable metal, does not have inconsistent problem in human body, and because human body contains magnesium elements, so the magnesium alloy degraded time can not cause toxic reaction.
2, several main unit 1 are along the axial and circumferential of support and are arranged symmetrically with, therefore, the present invention have metal coverage rate moderate, preferably radial support power, compliance good, in the balloon expandable process, homogeneous deformation, easy fracture, not safe to use.And structure relatively simply is easy to processing, can reach few complication, improves the purpose of patients ' life quality.
3, being connected by the roundlet segmental arc of the semicircular ring in main unit of the present invention and quadrant ring, the roundlet segmental arc can dispersive stress, during the coronary artery bracket expanded radially, can reduce elastic recoil.
4, circumferential connection of the present invention connects by the straight line connector, can effectively increase the radial deformation capabilities of support, does not produce obvious axial retraction simultaneously, is convenient to accurate setting and location after support is expanded.
Description of drawings
Fig. 1 is the expanded view of magnesium alloy coronary artery bracket of the present invention; Fig. 2 is the structural front view of main unit 1.
The specific embodiment
the specific embodiment one: present embodiment is described in conjunction with Fig. 1 and Fig. 2, the support of present embodiment reticulates circular tube structure by magnesium alloy through laser engraving, described netty circular tube structure is comprised of several main unit 1 and several straight line connectors 2, each main unit 1 is by a semicircular ring 1-1, two quadrant ring 1-2 and two circular arc 1-3 form, two quadrant ring 1-2 are symmetricly set on the two ends of semicircular ring 1-1, and be connected by circular arc 1-3 between quadrant ring 1-2 and semicircular ring 1-1, circular arc 1-3's is recessed to the center towards semicircular ring 1-1, several main unit 1 have two to four along the axially-aligned of webmaster, several main unit 1 have eight to 18 along the circumferential arrangement of webmaster, in several main unit 1 of circumferential arrangement, every adjacent two main unit 1 are symmetrical arranged with a straight line connector 2, straight line connector 2 of circular arc top connection of every adjacent two semicircular ring 1-1.Main unit 1 can be used as coating stent of medicine, struts in process in expansion, and semicircular ring 1-1 and two quadrant ring 1-2 distortion are less, are conducive to the maintenance of medication coat, have reduced medication coat and have peeled off the risk of bringing.
The specific embodiment two: the external diameter of the netty circular tube structure of present embodiment is Φ 1mm~Φ 5mm, and wall thickness is 0.1mm~0.2mm, and the length of described netty circular tube structure is 5mm~50mm.Other composition and annexation are identical with the specific embodiment one.
The specific embodiment three: in conjunction with Fig. 1, present embodiment is described, the length of the straight line connector 2 of present embodiment is 0.1mm~0.3mm.Other composition and annexation are identical with the specific embodiment one or two.
The specific embodiment four: in conjunction with Fig. 2, present embodiment is described, the radius of the semicircular ring 1-1 of present embodiment is 0.3mm~0.6mm.Other composition and annexation are identical with the specific embodiment three.
The specific embodiment five: in conjunction with Fig. 2, present embodiment is described, the radius of the quadrant ring 1-2 of present embodiment is 0.3mm~0.6mm.Other composition and annexation are identical with the specific embodiment four.
The specific embodiment six: several main unit 1 of present embodiment have three along the axially-aligned of webmaster.Other composition and annexation are identical with the specific embodiment five.
The specific embodiment seven: in conjunction with Fig. 1, present embodiment is described, several main unit 1 of present embodiment have eight along the circumferential arrangement of webmaster.Other composition and annexation are identical with the specific embodiment six.

Claims (7)

1. magnesium alloy coronary artery bracket, described support reticulates circular tube structure by magnesium alloy through laser engraving, described netty circular tube structure is comprised of several main unit (1) and several straight line connectors (2), each main unit (1) is by a semicircular ring (1-1), two quadrant rings (1-2) and two circular arcs (1-3) form, two quadrant rings (1-2) are symmetricly set on the two ends of semicircular ring (1-1), and be connected by circular arc (1-3) between quadrant ring (1-2) and semicircular ring (1-1), circular arc (1-3) recessed to the center towards semicircular ring (1-1), several main unit (1) have two to four along the axially-aligned of webmaster, several main unit (1) have eight to 18 along the circumferential arrangement of webmaster, in several main unit (1) of circumferential arrangement, every adjacent two main unit (1) are symmetrical arranged with a straight line connector (2), a circular arc top connection straight line connector (2) of every adjacent two semicircular ring (1-1).
2. a kind of magnesium alloy coronary artery bracket according to claim 1, it is characterized in that: the external diameter of described netty circular tube structure is Φ 1mm~Φ 5mm, and wall thickness is 0.1mm~0.2mm, and the length of described netty circular tube structure is 5mm~50mm.
3. described a kind of magnesium alloy coronary artery bracket according to claim 1 and 2, it is characterized in that: the length of described straight line connector (2) is 0.1mm~0.3mm.
4. a kind of magnesium alloy coronary artery bracket according to claim 3, it is characterized in that: the radius of described semicircular ring (1-1) is 0.3mm~0.6mm.
5. a kind of magnesium alloy coronary artery bracket according to claim 4, it is characterized in that: the radius of described quadrant ring (1-2) is 0.3mm~0.6mm.
6. a kind of magnesium alloy coronary artery bracket according to claim 5, it is characterized in that: several main unit (1) have three along the axially-aligned of webmaster.
7. a kind of magnesium alloy coronary artery bracket according to claim 6, it is characterized in that: several main unit (1) have eight along the circumferential arrangement of webmaster.
CN201210442913.XA 2012-11-08 2012-11-08 Magnesium alloy coronary support frame Active CN103110465B (en)

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Application Number Priority Date Filing Date Title
CN201210442913.XA CN103110465B (en) 2012-11-08 2012-11-08 Magnesium alloy coronary support frame

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Application Number Priority Date Filing Date Title
CN201210442913.XA CN103110465B (en) 2012-11-08 2012-11-08 Magnesium alloy coronary support frame

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CN103110465B CN103110465B (en) 2015-02-25

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105559953A (en) * 2015-12-11 2016-05-11 青岛尤尼科技有限公司 Manufacturing method of magnesium alloy cardiovascular stent, stent and perform of stent
CN108186175A (en) * 2018-02-02 2018-06-22 青岛市中心医院 A kind of novel and multifunctional Internal Medicine-Cardiovascular Dept. coronary artery bracket
US10463513B2 (en) 2015-07-20 2019-11-05 Shanghai Jiao Tong University Biodegradable metallic vascular stent and application thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2664617Y (en) * 2003-11-13 2004-12-22 美国宙迪公司 Human body tract lumen rack
US20100262221A1 (en) * 2005-09-19 2010-10-14 Cook Incorporated Graft with bioabsorbable support frame
CN202184823U (en) * 2011-05-20 2012-04-11 浙江康正医疗器械有限公司 Micropore coronary absorbable stent
CN202277400U (en) * 2011-05-16 2012-06-20 北京众合赛福医疗科技发展有限公司 Cobalt, nickel and chrome alloy blood vessel stent

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2664617Y (en) * 2003-11-13 2004-12-22 美国宙迪公司 Human body tract lumen rack
US20100262221A1 (en) * 2005-09-19 2010-10-14 Cook Incorporated Graft with bioabsorbable support frame
CN202277400U (en) * 2011-05-16 2012-06-20 北京众合赛福医疗科技发展有限公司 Cobalt, nickel and chrome alloy blood vessel stent
CN202184823U (en) * 2011-05-20 2012-04-11 浙江康正医疗器械有限公司 Micropore coronary absorbable stent

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10463513B2 (en) 2015-07-20 2019-11-05 Shanghai Jiao Tong University Biodegradable metallic vascular stent and application thereof
CN105559953A (en) * 2015-12-11 2016-05-11 青岛尤尼科技有限公司 Manufacturing method of magnesium alloy cardiovascular stent, stent and perform of stent
CN108186175A (en) * 2018-02-02 2018-06-22 青岛市中心医院 A kind of novel and multifunctional Internal Medicine-Cardiovascular Dept. coronary artery bracket

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