CN103100050B - Chinese medicament for treating angina - Google Patents

Chinese medicament for treating angina Download PDF

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Publication number
CN103100050B
CN103100050B CN201310042796.2A CN201310042796A CN103100050B CN 103100050 B CN103100050 B CN 103100050B CN 201310042796 A CN201310042796 A CN 201310042796A CN 103100050 B CN103100050 B CN 103100050B
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parts
radix
chinese medicament
blood
chinese
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CN103100050A (en
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石玉生
吕红梅
季顺欣
沈建军
杨克科
张艳
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Shi Yusheng
Zhang Yan
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Abstract

The invention belongs to the field of Chinese medicaments, and particularly discloses a Chinese medicament for treating angina. The Chinese medicament for treating the angina is prepared from the following raw materials according to certain weight parts: allium macrostemon, dried tangerine peel, radix curcumae, nutgrass galingale rhizome, trichosanthes kirilowii maxim, raw rehmannia, red-rooted salvia roots, hemlock parsley, cattail pollen, purple perilla fruits, plum blossom borneol, lily, old rice, coconut shell and camphora wood. The Chinese medicament has the advantages of simpliness of preparation, good absorption effect, long drug effect duration, remarkable curative effect, no side effect, high safety and high production cost, and is advantageous to reducing symptoms of a patient in time.

Description

One treats anginal Chinese medicine
(1) technical field
The present invention relates to application in TCM field, particularly one treats anginal Chinese medicine.
(2) background technology
Angina pectoris refers to coronary insufficiency, and cardiac muscle transient ischemia sharply, the clinical syndrome caused by anoxia, belong to a kind of common clinical type of coronary heart disease.Often bring out because of excited or stronger physical exertion, often show the ictal angor in pareordia or constriction clinically, after being positioned at breastbone or left front breast, left shoulder arm can be emitted to, last of short duration, rest or buccal nitroglycerine tablets can be alleviated, and belong to " thoracic obstruction " category of the traditional Chinese medical science.The main pathogenesis of primary disease is yin-cold excess, yin subjugating yang position, functional activity of QI being not smooth, and the character of its pathogenesis is deficiency in origin and excess in superficiality.
At present, the medicine of patient with angina pectoris informal dress is more, but conventional medicine has pills for curing heart disease, Radix Salviae Miltiorrhizae Tabellae etc., although have certain curative effect at that time, but can not fundamentally effectively cure, thoroughly can not cure angina pectoris disease is a medical research difficult problem always, and patient with angina pectoris wishes that new treatment angina pectoris medicine comes out.
(3) summary of the invention
The present invention, in order to make up the deficiencies in the prior art, provides and a kind ofly prepares the anginal Chinese medicine for the treatment of simple, evident in efficacy.
The present invention is achieved through the following technical solutions:
One treats anginal Chinese medicine, is made up of the raw material of following parts by weight:
Bulbus Allii Macrostemonis 4 ~ 10 parts, Pericarpium Citri Reticulatae 3 ~ 9 parts, Radix Curcumae 3 ~ 9 parts, Rhizoma Cyperi 4 ~ 10 parts, Fructus Trichosanthis 9 ~ 15 parts, Radix Rehmanniae 9 ~ 15 parts, Radix Salviae Miltiorrhizae 6 ~ 12 parts, Rhizoma Chuanxiong 3 ~ 9 parts, Pollen Typhae 4 ~ 10 parts, Fructus Perillae 4 ~ 10 parts, MEIHUA BINGPIAN 0.1 ~ 0.3 part, Bulbus Lilii 6 ~ 12 parts, Oryza sativa L. 9 ~ 15 parts, Exocarpium cocois (Cocos nucifera L) 1 ~ 3 part, Radix Cinnamomi Camphorae 3 ~ 9 parts.
The weight proportion of its preferred each raw material is:
Bulbus Allii Macrostemonis 7 parts, Pericarpium Citri Reticulatae 6 parts, Radix Curcumae 6 parts, Rhizoma Cyperi 7 parts, Fructus Trichosanthis 12 parts, Radix Rehmanniae 12 parts, Radix Salviae Miltiorrhizae 9 parts, Rhizoma Chuanxiong 6 parts, Pollen Typhae 7 parts, Fructus Perillae 7 parts, MEIHUA BINGPIAN 0.2 part, Bulbus Lilii 9 parts, Oryza sativa L. 12 parts, Exocarpium cocois (Cocos nucifera L) 2 parts, Radix Cinnamomi Camphorae 6 parts.
Chinese medicine of the present invention is powder or pill, after being cleaned up by various raw material, plays powder mixing, makes powder or pill, quantitatively take.
The pharmaceutical characteristic of each raw material is as follows:
Bulbus Allii Macrostemonis: the chest stuffiness relieving of regulating the flow of vital energy, activating YANG and eliminating stagnation.Cure mainly the thorough back of the body of obstruction of qi in the chest and cardialgia, breast gastral cavity painful abdominal mass is vexed, cough with asthma abundant expectoration, epigastric pain, heavy after letting out dysentery, leucorrhea, furuncle carbuncle;
Pericarpium Citri Reticulatae: regulate the flow of vital energy in adjusting, stopping nausea and vomiting by lowering the adverse flow of QI, drying dampness to eliminate phlegm.Cure mainly chest and diaphragm full vexed, abdominal distention, anorexia, vomiting, hiccup; Cough with copious phlegm;
Radix Curcumae: promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, clear away heart-fire removing heat from blood, function of gallbladder promoting.The all pains of pillar breast abdomen side of body rib, dysmenorrhea , mass in the abdomen, calentura coma, demented, spit blood, epistaxis, stranguria with blood, sand Stranguria, jaundice;
Rhizoma Cyperi: resolving depression of regulating the flow of vital energy, regulating menstruation, antiabortive.Cure mainly distending pain over the hypochondrium, distending pain of the breast, hernia pain, menoxenia, gastral cavity abdomen feeling of fullness pain, belch acid regurgitation, vomiting and nausea, abdominal pain during menstruation;
Fructus Trichosanthis: removing heat-phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizes laxation.Cure mainly cough due to lung-heat, the thoracic obstruction, blocked-up chest, quench one's thirst, constipation, carbuncle sore tumefacting virus;
Fructus Crotonis: rush down lower cold long-pending, detumescence of relieving oedema or abdominal distension through diuresis or purgation, dispelling phlegm and relieving sore-throat, phagedenoma parasite killing.Cure mainly the distension and fullness of the chest and abdomen shoot caused by cold-evil's food stagnation, constipation, dysentery, edema enlarged abdomen, phlegm retention dyspnea with fullness of the chest;
Radix Rehmanniae: have another name called Radix Rehmanniae, clearing away heat from blood, easy cloudy blood, promoting blood circulation.Cure mainly epidemic febrile disease heating, jaundice, the haematemesis caused by heat in blood, epistaxis, metrorrhagia, hematuria, has blood in stool, and quenches one's thirst, hectic fever due to YIN-deficiency consumptive fever;
Radix Salviae Miltiorrhizae: blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, removing heat from blood eliminating carbuncle.Cure mainly trusted subordinate's pain, pyretic arthralgia swells and ache, traumatic injury, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore;
Rhizoma Chuanxiong: blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping.Cure mainly menoxenia, amenorrhea dysmenorrhea, the stasis of blood in puerperal stagnant stomachache , mass in the abdomen lump, pain in chest and hypochondrium, has a headache dizzy, anemofrigid-damp arthralgia;
Pollen Typhae: hemostasis, blood stasis dispelling, diuresis.Cure mainly haematemesis, spitting of blood, epistaxis, dysentery, has blood in stool, metrorrhagia, traumatic hemorrhage, trusted subordinate's cold type of pain, amenorrhea suffer from abdominal pain, puerperal the stasis of blood pain, dysmenorrhea, tumbling and swelling;
Fructus Perillae: sending down the abnormal ascending QI, expectorant, relievings asthma, intestine moistening.Cure mainly expectorant and stop up QI rising in reverse order, cough and asthma, dryness of the intestine constipation;
MEIHUA BINGPIAN: refreshment of having one's ideas straightened out, heat radiation pain relieving, improving eyesight removing nebula.Cure mainly apoplexy locked mouth, calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, conjunctivitis, sore throat, aphtha, carbuncle, hemorrhoid;
Bulbus Lilii: nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.Cure mainly deficiency of YIN chronic cough, sputum mixed with blood, the calentura later stage, waste heat is clear, or the unsuccessful caused fidgets due to deficiency palpitation with fear of feelings will, insomnia and dreamful sleep, absentminded;
Oryza sativa L.: adjust the intestines and stomach, diuresis, relieving thirst and restlessness.Cure mainly weakness of the spleen and stomach, lack of appetite and vomiting, fasting dysentery, excessive thirst.Appropriate 9-30
Exocarpium cocois (Cocos nucifera L): dispel the wind, dampness removing, antipruritic.Cure mainly syphilitic skin lesion, tinea corporis, tinea pedis;
Radix Cinnamomi Camphorae: warming middle-JIAO to relieve pain, and in, damp eliminating.Master looks gastralgia, and cholera is vomited and diarrhoea, rheumatic arthralgia, skin pruritus etc.
In formula, Bulbus Allii Macrostemonis, Pericarpium Citri Reticulatae, Fructus Trichosanthis, Fructus Perillae are mainly used in regulate the flow of vital energy the chest stuffiness relieving, activating YANG and eliminating stagnation, stopping nausea and vomiting by lowering the adverse flow of QI, drying dampness to eliminate phlegm; Add and join Radix Curcumae, Rhizoma Cyperi, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, be mainly used in promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, clear away heart-fire removing heat from blood; Joining again Fructus Crotonis, Pollen Typhae, Exocarpium cocois (Cocos nucifera L), Radix Cinnamomi Camphorae, cold to amass down for rushing down, detumescence of relieving oedema or abdominal distension through diuresis or purgation, dispelling phlegm and relieving sore-throat and middle damp eliminating; Join Radix Rehmanniae, MEIHUA BINGPIAN, Bulbus Lilii, Oryza sativa L. again, for the tonifying YIN that purifies the blood, logical blood regulating menstruation, tranquilizing by nourishing the heart, nourishing YIN and moistening the lung.
The present invention with blood circulation promoting and blood stasis dispelling, regulate the flow of vital energy activate yang, YIN nourishing and QI supplementing is for the rule for the treatment of, multiple medical material combination is collaborative, be mainly used in regulating the flow of vital energy the chest stuffiness relieving, activating YANG and eliminating stagnation, drying dampness to eliminate phlegm, promoting blood circulation and stopping pain, circulation of qi promoting dissipating blood stasis and middle damp eliminating, adjust blood dysmenorrhea, nourishing YIN and moistening the lung, angina pectoris is had significant therapeutic effect.
Clinical observation:
(1) clinical data
The present inventor in 2006 so far, carries out clinical observation treatment to 359 routine patient with angina pectoris, 41 ~ 67 years old age.
(2) Therapeutic Method
Oral, three times on the one, each 2 ~ 5g, one after each meal.Calculate treatment time according to conditions of patients weight, patients with mild takes about 10 ~ 15 days, and severe case serve on 20 ~ 60 days and can fully recover.
(3) curative effect determinate standard
Criterion of therapeutical effect is with reference to criterion of therapeutical effect relevant in " disease of tcm judgement criterion of therapeutical effect ".
Cure: clinical symptoms all disappears, and lab testing is normal.
Effective: clinical symptoms disappears substantially, test chamber checks that each index of correlation is close to normal level.
Effective: clinical symptom relief, test chamber checks that each index of correlation makes moderate progress, and sign is improved.
Invalid: clinical symptoms is without being clearly better or increasing the weight of.
(4) clinical effectiveness
Clinical cure 291 example (81.06%), effective 40 examples (11.14%), effective 23 examples (6.41%), invalid 5 examples (1.39%), total effective rate is 98.61%.
The present invention prepares simply, good absorbing effect, and duration of efficacy is long, evident in efficacy, has no side effect, and safety is high, and production cost is low, is conducive to sufferer and alleviates condition of illness in time.
(4) detailed description of the invention
Embodiment 1:
Get Bulbus Allii Macrostemonis 4g, Pericarpium Citri Reticulatae 3g, Radix Curcumae 3g, Rhizoma Cyperi 4g, Fructus Trichosanthis 9g, Radix Rehmanniae 9g, Radix Salviae Miltiorrhizae 6g, Rhizoma Chuanxiong 3g, Pollen Typhae 4g, Fructus Perillae 4g, MEIHUA BINGPIAN 0.1g, Bulbus Lilii 6g, Oryza sativa L. 9g, Exocarpium cocois (Cocos nucifera L) 1g, Radix Cinnamomi Camphorae 3g, above-mentioned raw materials is cleaned up, play powder mixing, make powder or pill.
Usage and dosage: oral, three times on the one, each 2 ~ 5g, one after each meal.
Embodiment 2:
Get Bulbus Allii Macrostemonis 10g, Pericarpium Citri Reticulatae 9g, Radix Curcumae 9g, Rhizoma Cyperi 10g, Fructus Trichosanthis 15g, Radix Rehmanniae 15g, Radix Salviae Miltiorrhizae 12g, Rhizoma Chuanxiong 9g, Pollen Typhae 10g, Fructus Perillae 10g, MEIHUA BINGPIAN 0.3g, Bulbus Lilii 12g, Oryza sativa L. 15g, Exocarpium cocois (Cocos nucifera L) 3g, Radix Cinnamomi Camphorae 9g, above-mentioned raw materials is cleaned up, play powder mixing, make powder or pill.
Usage and dosage: oral, three times on the one, each 2 ~ 5g, one after each meal.
Embodiment 3:
Get Bulbus Allii Macrostemonis 7g, Pericarpium Citri Reticulatae 6g, Radix Curcumae 6g, Rhizoma Cyperi 7g, Fructus Trichosanthis 12g, Radix Rehmanniae 12g, Radix Salviae Miltiorrhizae 9g, Rhizoma Chuanxiong 6g, Pollen Typhae 7g, Fructus Perillae 7g, MEIHUA BINGPIAN 0.2g, Bulbus Lilii 9g, Oryza sativa L. 12g, Exocarpium cocois (Cocos nucifera L) 2g, Radix Cinnamomi Camphorae 6g, above-mentioned raw materials is cleaned up, play powder mixing, make powder or pill.
Usage and dosage: oral, three times on the one, each 2 ~ 5g, one after each meal.

Claims (1)

1. the anginal Chinese medicine for the treatment of, it is characterized by, make powder or pill by the raw material of following parts by weight: Bulbus Allii Macrostemonis 7 parts, Pericarpium Citri Reticulatae 6 parts, Radix Curcumae 6 parts, Rhizoma Cyperi 7 parts, Fructus Trichosanthis 12 parts, Radix Rehmanniae 12 parts, Radix Salviae Miltiorrhizae 9 parts, Rhizoma Chuanxiong 6 parts, Pollen Typhae 7 parts, Fructus Perillae 7 parts, MEIHUA BINGPIAN 0.2 part, Bulbus Lilii 9 parts, Oryza sativa L. 12 parts, Exocarpium cocois (Cocos nucifera L) 2 parts, Radix Cinnamomi Camphorae 6 parts.
CN201310042796.2A 2013-02-04 2013-02-04 Chinese medicament for treating angina Expired - Fee Related CN103100050B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1334121A (en) * 2001-08-31 2002-02-06 石家庄以岭药业有限公司 Medicinal composition for restoring cardiac collaterals and its application
CN101698090A (en) * 2009-11-19 2010-04-28 泰一和浦(北京)中医药研究院有限公司 Traditional Chinese medicine composite for treating coma and heart syncope symptoms and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1334121A (en) * 2001-08-31 2002-02-06 石家庄以岭药业有限公司 Medicinal composition for restoring cardiac collaterals and its application
CN101698090A (en) * 2009-11-19 2010-04-28 泰一和浦(北京)中医药研究院有限公司 Traditional Chinese medicine composite for treating coma and heart syncope symptoms and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
中医中药治疗冠心病心绞痛近况;韦丽贞;《右江民族医学院学报》;19951231(第1期);全文 *

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