CN103080335B - 选择甲基化标记的方法 - Google Patents

选择甲基化标记的方法 Download PDF

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Publication number
CN103080335B
CN103080335B CN201180034459.8A CN201180034459A CN103080335B CN 103080335 B CN103080335 B CN 103080335B CN 201180034459 A CN201180034459 A CN 201180034459A CN 103080335 B CN103080335 B CN 103080335B
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dna
sharp
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CN103080335A (zh
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A·P·米德
M·J·威尔金森
C·M·R·罗佩茨
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Aberystwyth University
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201180034459.8A 2010-05-12 2011-05-12 选择甲基化标记的方法 Expired - Fee Related CN103080335B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1007944.0 2010-05-12
GBGB1007944.0A GB201007944D0 (en) 2010-05-12 2010-05-12 Methods
PCT/GB2011/000733 WO2011141711A1 (fr) 2010-05-12 2011-05-12 Procédés de sélection de marqueurs de méthylation

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CN103080335A CN103080335A (zh) 2013-05-01
CN103080335B true CN103080335B (zh) 2015-04-29

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EP (1) EP2580347A1 (fr)
JP (1) JP2013526271A (fr)
CN (1) CN103080335B (fr)
AU (1) AU2011251767A1 (fr)
BR (1) BR112012028957A2 (fr)
GB (1) GB201007944D0 (fr)
WO (1) WO2011141711A1 (fr)

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* Cited by examiner, † Cited by third party
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NZ717423A (en) * 2012-09-20 2017-08-25 Univ Hong Kong Chinese Non-invasive determination of methylome of fetus or tumor from plasma
CN105256379A (zh) * 2015-11-23 2016-01-20 武汉大学 一种新的基因组简化甲基化测序文库的制备方法
CN106755534B (zh) * 2017-03-01 2020-06-16 北京林业大学 一种植物dna甲基化组织特异性获取方法
CN107967410B (zh) * 2017-11-27 2021-07-30 电子科技大学 一种面向基因表达与甲基化数据的融合方法
CN110055326B (zh) * 2019-03-08 2022-10-11 宁波大学 预测肾透明细胞癌复发转移的分子标记物及其应用
CN113832163B (zh) * 2021-10-20 2023-06-02 浙江师范大学 有效提高植物果实生物量的方法

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GB1007944A (en) 1963-09-04 1965-10-22 Spartan Steel & Alloys Ltd Improvements in and relating to the casting of metals and alloys
DE60211324T2 (de) * 2001-03-01 2007-02-08 Epigenomics Ag Verfahren und rechnerprogrammprodukte zur erfassung der biologischen wirkung und/oder aktivität von arzneimitteln, chemischen substanzen und/oder pharmazeuitschen verbindungen auf der basis ihrer effekte auf den methylierungszustand der dna
US20060183128A1 (en) 2003-08-12 2006-08-17 Epigenomics Ag Methods and compositions for differentiating tissues for cell types using epigenetic markers
US20060278241A1 (en) * 2004-12-14 2006-12-14 Gualberto Ruano Physiogenomic method for predicting clinical outcomes of treatments in patients
US20070292866A1 (en) 2005-12-08 2007-12-20 Ambergen, Inc. Diagnosing human diseases by detecting DNA methylation changes
US7754428B2 (en) 2006-05-03 2010-07-13 The Chinese University Of Hong Kong Fetal methylation markers
GB0714058D0 (en) 2007-07-19 2007-08-29 Abertec Ltd detection of methylation in nucleic acid sequences

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Stress-induced DNA Methylation changes and their heritability in asexual dandelions;KOEN J.F. VERHOEVEN et al.;《New Phytologist》;20100301;第185卷(第4期);摘要，表1 *

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AU2011251767A1 (en) 2012-12-20
GB201007944D0 (en) 2010-06-30
EP2580347A1 (fr) 2013-04-17
CN103080335A (zh) 2013-05-01
BR112012028957A2 (pt) 2019-09-24
JP2013526271A (ja) 2013-06-24
WO2011141711A1 (fr) 2011-11-17

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