CN103071118A - 一种治疗十二指肠炎的中药 - Google Patents
一种治疗十二指肠炎的中药 Download PDFInfo
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Abstract
本发明涉及一种治疗十二指肠炎的中药，由以下重量配比的药材制备而成：天青地白12份、三颗针10份、莪术8份、刘寄奴7份、白芍14份、连翘12份、青黛12份、穿心莲8份、菟丝子8份、杜仲8份、山药14份、金樱子12份、制马钱子10份、陈皮12份。临床实验证明，本发明能够安全有效治疗十二指肠炎。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗十二指肠炎的中药。
背景技术
十二指肠炎是指十二指肠的炎症，分为原发性和继发性两种，原发性者也称非特异性十二指肠炎。本病临床症状缺乏特征性，主要表现为上腹部疼痛、恶心、呕吐、呕血和黑便，有时和十二指肠溃疡不易区别，单纯临床症状无法确诊，本病常与慢性胃炎、慢性肝炎、肝硬化、胆道疾患或慢性胰腺炎并存。
对于十二指肠炎目前尚缺少公认安全有效的治疗药物。
本发明中药所涉及药材的研究现状如下：
天青地白【来源】于菊科植物日本鼠曲草全草。性：甘、凉。【功能主治】解表，清热，明目，利尿的功效。治疗感冒，咳嗽，头痛，喉痛，目赤翳鄣，小便热闭，淋浊，白带，痈肿，疔疮。
三颗针【来源】于小檗科植物刺黑珠、毛叶小檗、黑石珠等的根皮或茎皮。性寒，微苦。【功能主治】清热，利湿，散瘀的功效。治疗赤痢，黄疸，咽痛，目赤，跌打损伤。
莪术【来源】莪术为多年生宿根草本。姜科植物蓬莪术、广西莪术或温郁金的干燥根茎。【功能主治】行气破血，消积止痛。用于燀瘕痞块，瘀血经闭，食积胀痛；早期宫颈癌。
刘寄奴【来源】菊科植物奇蒿的全草。【功能主治】疗伤止血，破血痛经，消食化积，醒脾开胃的功效。它可用于急性黄疸型肝炎，牙痛，慢性气管炎，口腔炎，咽喉炎，扁桃体炎，肾炎，疟疾；外用治眼结膜炎，中耳炎，疮疡，湿疹，外伤出血。
白芍【来源】为双子叶植物药毛茛科植物芍药(栽培种)的根。已栽植3～4年的芍药根，除去根茎及须根，洗净，刮去粗皮，入沸水中略煮，使芍根发软，捞出晒干。【功能主治】养血柔肝，缓中止痛，敛阴收汗。治胸腹胁肋疼痛，泻痢腹痛，自汗盗汗，阴虚发热，月经不调，崩漏，带下。
连翘【来源】连翘为木犀科植物连翘的果实，内含挥发油，连翘酚，黄酮甙，生物碱等；【功能主治】连翘有广谱抗菌作用，抗炎、镇吐、利尿和强心；所含黄酮甙能增强毛细血管的致密度，其性微寒，味苦，清热解毒，散结消肿，适用于温热，丹毒，斑疹，痈疡肿毒及过敏性紫癜等。
青黛【来源】为爵床科植物马蓝Baphicacanthus cusia、蓼科植物蓼蓝Polygonum tinctorium或十字花科植物菘蓝Isatis indigotica Fort.的叶或茎叶经加工制得的干燥粉末、团块或颗粒。【功能主治】性寒味咸，归肝经。具有清热解毒，凉血消斑，泻火定惊之功效。用于温毒发斑，血热吐衄，胸痛咳血，口疮，痄腮，喉痹，小儿惊痫。
穿心莲【来源】：爵床科植物穿心莲(圆锥须药草)Andrographis paniculata(Burm.f.)Nees的干燥地上部分。秋初茎叶茂盛时采割，晒干。【功能主治】清热解毒，凉血，消肿，燥湿。主治：感冒发热，咽喉肿痛，口舌生疮，顿咳劳嗽，泄泻痢疾，热淋涩痛，痈肿疮疡，毒蛇咬伤。
菟丝子【来源】双子叶植物药旋花科植物菟丝子、南方菟丝子、金灯藤等的种子。【功能主治】具有补肾益精、养肝明目、固胎止泄之功效。
杜仲【来源】杜仲科植物杜仲(Eucommia ulmoides O1iver)的干燥树皮，是中国名贵滋补药材。【功能主治】补肝肾、强筋骨、降血压、安胎等诸多功效。
山药【来源】多年生草本植物，茎蔓生，常带紫色，块根圆柱形，叶子对生，卵形或椭圆形，花乳白色，雌雄异株。块根含淀粉和蛋白质。【功能主治】补脾养胃，生津益肺，补肾涩精。用于脾虚食少，久泻不止，肺虚喘咳，肾虚遗精，带下，尿频，虚热消渴。
金樱子【来源】常绿蔓性灌木，无毛根皮提制栲胶；果实入药。【功能主治】止咳平喘，抗痉挛，有利尿、补肾作用；抗菌消炎，降血脂。叶有解毒消肿作用；根药用，能活血散瘀、拔毒收敛、祛风驱湿。
制马钱子【来源】马钱科植物云南马钱的干燥成熟种子。主要成分是士的宁。【功能主治】治伤寒热病，咽喉痹痛，消痞块，散血热，消肿毒。治痈疽，恶疮。
陈皮【来源】芸香科植物橘及其栽培变种的成熟果皮。【功能主治】理气开胃，燥湿化痰，治脾胃病。
发明内容
本发明旨在提供一种治疗十二指肠炎的中药，通过选择合适的药材及其配比，达到安全有效治愈十二指肠炎的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗十二指肠炎的中药，其特征在于，由以下重量配比的药材制备而成：天青地白12份、三颗针10份、莪术8份、刘寄奴7份、白芍14份、连翘12份、青黛12份、穿心莲8份、菟丝子8份、杜仲8份、山药14份、金樱子12份、制马钱子10份、陈皮12份。
下面结合临床实验数据说明本发明的有益效果：
11、一般资料
发明人2010年6月-2011年10月间共收集67例十二指肠炎的门诊患者，年龄12-28岁，病程0.5-7年。随机分为：治疗组45例，空白组22例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗组口服本发明按照具体实施例1制得的胶囊，早晚各一次。疗程15天。
2.2空白组口服安慰剂胶囊，早晚各一次。疗程15天。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常。好转：临床症状减轻，病情得到控制，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1两组疗效比较
可见，本发明制得的药物能够安全有效治十二指肠炎。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取：天青地白12克、三颗针10克、莪术8克、刘寄奴7克、白芍14克、连翘12克、青黛12克、穿心莲8克、菟丝子8克、杜仲8克、山药14克、金樱子12克、制马钱子10克、陈皮12克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗十二指肠炎。口服，每日分早晚两次服用。
具体实施例2
称取：天青地白12克、三颗针10克、莪术8克、刘寄奴7克、白芍14克、连翘12克、青黛12克、穿心莲8克、菟丝子8克、杜仲8克、山药14克、金樱子12克、制马钱子10克、陈皮12克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，粉碎，即得符合正常成人1天用量的散剂。
用于治疗十二指肠炎。口服，每日分早晚两次服用。
具体实施例3
称取：天青地白12克、三颗针10克、莪术8克、刘寄奴7克、白芍14克、连翘12克、青黛12克、穿心莲8克、菟丝子8克、杜仲8克、山药14克、金樱子12克、制马钱子10克、陈皮12克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人1天用量的颗粒剂。用于治疗十二指肠炎。口服，每日分早晚两次服用。
Claims (1)
1.一种治疗十二指肠炎的中药，其特征在于，由以下重量配比的药材制备而成：天青地白12份、三颗针10份、莪术8份、刘寄奴7份、白芍14份、连翘12份、青黛12份、穿心莲8份、菟丝子8份、杜仲8份、山药14份、金樱子12份、制马钱子10份、陈皮12份。
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| CN1085786A (zh) * | 1993-05-13 | 1994-04-27 | 贺先楼 | 治疗胃肠疾病的中成药及制作工艺 |
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| CN102058780A (zh) * | 2010-12-31 | 2011-05-18 | 张林祥 | 一种治疗溃疡性结肠炎的灌肠中药剂 |
| CN102233027A (zh) * | 2010-04-30 | 2011-11-09 | 刘国昌 | 一种治疗肠炎的中药 |
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| CN1085786A (zh) * | 1993-05-13 | 1994-04-27 | 贺先楼 | 治疗胃肠疾病的中成药及制作工艺 |
| CN1380098A (zh) * | 2002-05-20 | 2002-11-20 | 张勇飞 | 一种抗感染复合制剂及其制备方法 |
| CN101884765A (zh) * | 2009-05-11 | 2010-11-17 | 刘汉光 | 用于治疗大腹便便俗称啤酒肚的药 |
| CN102233027A (zh) * | 2010-04-30 | 2011-11-09 | 刘国昌 | 一种治疗肠炎的中药 |
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